Development of a potent and selective chemical probe for the pleiotropic kinase CK2 von Wells, Carrow I., Drewry, David H., Pickett, Julie E., Tjaden, Amelie, Krämer, Andreas, Müller, Susanne, Gyenis, Laszlo, Menyhart, Daniel, Litchfield, David W., Knapp, Stefan, Axtman, Alison D.

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Progress towards a public chemogenomic set for protein kinases and a call for contributions von Drewry, David H, Wells, Carrow I, Andrews, David M, Angell, Richard, Al-Ali, Hassan, Axtman, Alison D, Capuzzi, Stephen J, Elkins, Jonathan M, Ettmayer, Peter, Frederiksen, Mathias, Gileadi, Opher, Gray, Nathanael, Hooper, Alice, Knapp, Stefan, Laufer, Stefan, Luecking, Ulrich, Michaelides, Michael, Müller, Susanne, Muratov, Eugene, Denny, R Aldrin, Saikatendu, Kumar S, Treiber, Daniel K, Zuercher, William J, Willson, Timothy M

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Enhancements of screening collections to address areas of unmet medical need: an industry perspective von Drewry, David H, Macarron, Ricardo

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Discovery of I‑BRD9, a Selective Cell Active Chemical Probe for Bromodomain Containing Protein 9 Inhibition von Theodoulou, Natalie H, Bamborough, Paul, Bannister, Andrew J, Becher, Isabelle, Bit, Rino A, Che, Ka Hing, Chung, Chun-wa, Dittmann, Antje, Drewes, Gerard, Drewry, David H, Gordon, Laurie, Grandi, Paola, Leveridge, Melanie, Lindon, Matthew, Michon, Anne-Marie, Molnar, Judit, Robson, Samuel C, Tomkinson, Nicholas C. O, Kouzarides, Tony, Prinjha, Rab K, Humphreys, Philip G

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Comprehensive characterization of the Published Kinase Inhibitor Set von Elkins, Jonathan M, Fedele, Vita, Szklarz, Marta, Abdul Azeez, Kamal R, Salah, Eidarus, Mikolajczyk, Jowita, Romanov, Sergei, Sepetov, Nikolai, Huang, Xi-Ping, Roth, Bryan L, Al Haj Zen, Ayman, Fourches, Denis, Muratov, Eugene, Tropsha, Alex, Morris, Joel, Teicher, Beverly A, Kunkel, Mark, Polley, Eric, Lackey, Karen E, Atkinson, Francis L, Overington, John P, Bamborough, Paul, Müller, Susanne, Price, Daniel J, Willson, Timothy M, Drewry, David H, Knapp, Stefan, Zuercher, William J

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New Compound Sets Identified from High Throughput Phenotypic Screening Against Three Kinetoplastid Parasites: An Open Resource von Peña, Imanol, Pilar Manzano, M., Cantizani, Juan, Kessler, Albane, Alonso-Padilla, Julio, Bardera, Ana I., Alvarez, Emilio, Colmenarejo, Gonzalo, Cotillo, Ignacio, Roquero, Irene, de Dios-Anton, Francisco, Barroso, Vanessa, Rodriguez, Ana, Gray, David W., Navarro, Miguel, Kumar, Vinod, Sherstnev, Alexander, Drewry, David H., Brown, James R., Fiandor, Jose M., Julio Martin, J.

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Quantifying CDK inhibitor selectivity in live cells von Wells, Carrow I., Vasta, James D., Corona, Cesear R., Wilkinson, Jennifer, Zimprich, Chad A., Ingold, Morgan R., Pickett, Julie E., Drewry, David H., Pugh, Kathryn M., Schwinn, Marie K., Hwang, Byounghoon (Brian), Zegzouti, Hicham, Huber, Kilian V. M., Cong, Mei, Meisenheimer, Poncho L., Willson, Timothy M., Robers, Matthew B.

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Modulation of tau tubulin kinases (TTBK1 and TTBK2) impacts ciliogenesis von Bashore, Frances M., Marquez, Ariana B., Chaikuad, Apirat, Howell, Stefanie, Dunn, Andrea S., Beltran, Alvaro A., Smith, Jeffery L., Drewry, David H., Beltran, Adriana S., Axtman, Alison D.

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CaMKK2 in myeloid cells is a key regulator of the immune-suppressive microenvironment in breast cancer von Racioppi, Luigi, Nelson, Erik R., Huang, Wei, Mukherjee, Debarati, Lawrence, Scott A., Lento, William, Masci, Anna Maria, Jiao, Yiquin, Park, Sunghee, York, Brian, Liu, Yaping, Baek, Amy E., Drewry, David H., Zuercher, William J., Bertani, Francesca R., Businaro, Luca, Geradts, Joseph, Hall, Allison, Means, Anthony R., Chao, Nelson, Chang, Ching-yi, McDonnell, Donald P.

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Covalent inhibitors of EGFR family protein kinases induce degradation of human Tribbles 2 (TRIB2) pseudokinase in cancer cells von Foulkes, Daniel M, Byrne, Dominic P, Yeung, Wayland, Shrestha, Safal, Bailey, Fiona P, Ferries, Samantha, Eyers, Claire E, Keeshan, Karen, Wells, Carrow, Drewry, David H, Zuercher, William J, Kannan, Natarajan, Eyers, Patrick A

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Synergistic drug combinations and machine learning for drug repurposing in chordoma von Anderson, Edward, Havener, Tammy M., Zorn, Kimberley M., Foil, Daniel H., Lane, Thomas R., Capuzzi, Stephen J., Morris, Dave, Hickey, Anthony J., Drewry, David H., Ekins, Sean

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Profile of the GSK published protein kinase inhibitor set across ATP-dependent and-independent luciferases: implications for reporter-gene assays von Dranchak, Patricia, MacArthur, Ryan, Guha, Rajarshi, Zuercher, William J, Drewry, David H, Auld, Douglas S, Inglese, James

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EGFR inhibitors identified as a potential treatment for chordoma in a focused compound screen von Scheipl, Susanne, Barnard, Michelle, Cottone, Lucia, Jorgensen, Mette, Drewry, David H, Zuercher, William J, Turlais, Fabrice, Ye, Hongtao, Leite, Ana P, Smith, James A, Leithner, Andreas, Möller, Peter, Brüderlein, Silke, Guppy, Naomi, Amary, Fernanda, Tirabosco, Roberto, Strauss, Sandra J, Pillay, Nischalan, Flanagan, Adrienne M

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SGC-GAK-1: A Chemical Probe for Cyclin G Associated Kinase (GAK) von Asquith, Christopher R. M, Berger, Benedict-Tilman, Wan, Jing, Bennett, James M, Capuzzi, Stephen J, Crona, Daniel J, Drewry, David H, East, Michael P, Elkins, Jonathan M, Fedorov, Oleg, Godoi, Paulo H, Hunter, Debra M, Knapp, Stefan, Müller, Susanne, Torrice, Chad D, Wells, Carrow I, Earp, H. Shelton, Willson, Timothy M, Zuercher, William J

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Design of a Cyclin G Associated Kinase (GAK)/Epidermal Growth Factor Receptor (EGFR) Inhibitor Set to Interrogate the Relationship of EGFR and GAK in Chordoma von Asquith, Christopher R. M, Naegeli, Kaleb M, East, Michael P, Laitinen, Tuomo, Havener, Tammy M, Wells, Carrow I, Johnson, Gary L, Drewry, David H, Zuercher, William J, Morris, David C

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WNT Activates the AAK1 Kinase to Promote Clathrin-Mediated Endocytosis of LRP6 and Establish a Negative Feedback Loop von Agajanian, Megan J., Walker, Matthew P., Axtman, Alison D., Ruela-de-Sousa, Roberta R., Serafin, D. Stephen, Rabinowitz, Alex D., Graham, David M., Ryan, Meagan B., Tamir, Tigist, Nakamichi, Yuko, Gammons, Melissa V., Bennett, James M., Couñago, Rafael M., Drewry, David H., Elkins, Jonathan M., Gileadi, Carina, Gileadi, Opher, Godoi, Paulo H., Kapadia, Nirav, Müller, Susanne, Santiago, André S., Sorrell, Fiona J., Wells, Carrow I., Fedorov, Oleg, Willson, Timothy M., Zuercher, William J., Major, Michael B.

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LKB1 signaling and patient survival outcomes in hepatocellular carcinoma von Nguyen, Khoa, Hebert, Katherine, McConnell, Emily, Cullen, Nicole, Cheng, Thomas, Awoyode, Susanna, Martin, Elizabeth, Chen, Weina, Wu, Tong, Alahari, Suresh K., Izadpanah, Reza, Collins-Burow, Bridgette M., Lee, Sean B., Drewry, David H., Burow, Matthew E.

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Host-directed therapy, an untapped opportunity for antimalarial intervention von Wei, Ling, Adderley, Jack, Leroy, Didier, Drewry, David H., Wilson, Danny W., Kaushansky, Alexis, Doerig, Christian

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Strategic Fluorination to Achieve a Potent, Selective, Metabolically Stable, and Orally Bioavailable Inhibitor of CSNK2 von Ong, Han Wee, Yang, Xuan, Smith, Jeffery L, Taft-Benz, Sharon, Howell, Stefanie, Dickmander, Rebekah J, Havener, Tammy M, Sanders, Marcia K, Brown, Jason W, Couñago, Rafael M, Chang, Edcon, Krämer, Andreas, Moorman, Nathaniel J, Heise, Mark, Axtman, Alison D, Drewry, David H, Willson, Timothy M

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Defining the Neural Kinome: Strategies and Opportunities for Small Molecule Drug Discovery to Target Neurodegenerative Diseases von Krahn, Andrea I, Wells, Carrow, Drewry, David H, Beitel, Lenore K, Durcan, Thomas M, Axtman, Alison D

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