Targeting neuroinflammation in neuropathic pain and opioid use von Salvemini, Daniela, Doyle, Timothy M

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Sphingosine-1-phosphate receptor 1 activation in astrocytes contributes to neuropathic pain von Chen, Zhoumou, Doyle, Timothy M., Luongo, Livio, Largent-Milnes, Tally M., Giancotti, Luigino Antonio, Kolar, Grant, Squillace, Silvia, Boccella, Serena, Walker, John K., Pendleton, Alexander, Spiegel, Sarah, Neumann, William L., Vanderah, Todd W., Salvemini, Daniela

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Chemotherapy-induced pain is promoted by enhanced spinal adenosine kinase levels through astrocyte-dependent mechanisms von Wahlman, Carrie, Doyle, Timothy M., Little, Joshua W., Luongo, Livio, Janes, Kali, Chen, Zhoumou, Esposito, Emanuela, Tosh, Dilip K., Cuzzocrea, Salvatore, Jacobson, Kenneth A., Salvemini, Daniela

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Dysregulation of sphingolipid metabolism contributes to bortezomib-induced neuropathic pain von Stockstill, Katherine, Doyle, Timothy M, Yan, Xisheng, Chen, Zhoumou, Janes, Kali, Little, Joshua W, Braden, Kathryn, Lauro, Filomena, Giancotti, Luigino Antonio, Harada, Caron Mitsue, Yadav, Ruchi, Xiao, Wen Hua, Lionberger, Jack M, Neumann, William L, Bennett, Gary J, Weng, Han-Rong, Spiegel, Sarah, Salvemini, Daniela

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GPR160 de-orphanization reveals critical roles in neuropathic pain in rodents von Yosten, Gina Lc, Harada, Caron M, Haddock, Chris, Giancotti, Luigino Antonio, Kolar, Grant R, Patel, Ryan, Guo, Chun, Chen, Zhoumou, Zhang, Jinsong, Doyle, Timothy M, Dickenson, Anthony H, Samson, Willis K, Salvemini, Daniela

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Targeting the S1P/S1PR1 axis mitigates cancer-induced bone pain and neuroinflammation von Grenald, Shaness A., Doyle, Timothy M., Zhang, Hong, Slosky, Lauren M., Chen, Zhoumou, Largent-Milnes, Tally M., Spiegel, Sarah, Vanderah, Todd W., Salvemini, Daniela

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Sphingosine-1-phosphate receptor 1 activation in the central nervous system drives cisplatin-induced cognitive impairment von Squillace, Silvia, Niehoff, Michael L, Doyle, Timothy M, Green, Michael, Esposito, Emanuela, Cuzzocrea, Salvatore, Arnatt, Christopher K, Spiegel, Sarah, Farr, Susan A, Salvemini, Daniela

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Sexually dimorphic therapeutic response in bortezomib-induced neuropathic pain reveals altered pain physiology in female rodents von Stockstill, Katherine, Wahlman, Carrie, Braden, Kathryn, Chen, Zhoumou, Yosten, Gina L., Tosh, Dilip K., Jacobson, Kenneth A., Doyle, Timothy M., Samson, Willis K., Salvemini, Daniela

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Adenosine A3 receptor as a novel therapeutic target to reduce secondary events and improve neurocognitive functions following traumatic brain injury von Farr, Susan A, Cuzzocrea, Salvatore, Esposito, Emanuela, Campolo, Michela, Niehoff, Michael L, Doyle, Timothy M, Salvemini, Daniela

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Mini-Review: Mitochondrial dysfunction and chemotherapy-induced neuropathic pain von Doyle, Timothy M., Salvemini, Daniela

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Sphingosine-1-phosphate receptor subtype 1 activation in the central nervous system contributes to morphine withdrawal in rodents von Doyle, Timothy M, Hutchinson, Mark R, Braden, Kathryn, Janes, Kali, Staikopoulos, Vicky, Chen, Zhoumou, Neumann, William L, Spiegel, Sarah, Salvemini, Daniela

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Activation of Sphingosine-1-Phosphate Receptor 1 in the Spinal Cord Produces Mechanohypersensitivity Through the Activation of Inflammasome and IL-1β Pathway von Doyle, Timothy M., Chen, Zhoumou, Durante, Mariaconcetta, Salvemini, Daniela

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Activation of GPR183 by 7 α,25-Dihydroxycholesterol Induces Behavioral Hypersensitivity through Mitogen-Activated Protein Kinase and Nuclear Factor-κ B von Braden, Kathryn, Campolo, Michela, Li, Ying, Chen, Zhoumou, Doyle, Timothy M., Giancotti, Luigino Antonio, Esposito, Emanuela, Zhang, Jinsong, Cuzzocrea, Salvatore, Arnatt, Christopher Kent, Salvemini, Daniela

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CARTp/GPR160 mediates behavioral hypersensitivities in mice through NOD2 von Schafer, Rachel M, Giancotti, Luigino A, Chrivia, John C, Li, Ying, Mufti, Fatma, Kufer, Thomas A, Zhang, Jinsong, Doyle, Timothy M, Salvemini, Daniela

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Investigating the Molecular Mechanisms Driving 7α,25‐dihydroxycholesterol‐GPR183‐Induced Hypersensitivity von Braden, Kathryn, Campolo, Michela, Chen, Zhoumou, Giancotti, Luigi, Doyle, Timothy M., Esposito, Emanuela, Zhang, Jinsong, Cuzzocrea, Salvatore, Arnatt, Christopher K., Salvemini, Daniela

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Activation of sphingosine-1-phosphate receptor subtype 1 in the central nervous system contributes to morphine-induced hyperalgesia and antinociceptive tolerance in rodents von Doyle, Timothy M., Janes, Kali, Chen, Zhoumou, Grace, Peter M., Esposito, Emanuela, Cuzzocrea, Salvatore, Largent-Milnes, Tally M., Neumann, William L., Watkins, Linda R., Spiegel, Sarah, Vanderah, Todd W., Salvemini, Daniela

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GPR183-Oxysterol Axis in Spinal Cord Contributes to Neuropathic Pain von Braden, Kathryn, Giancotti, Luigino Antonio, Chen, Zhoumou, DeLeon, Chelsea, Latzo, Nick, Boehm, Terri, D’Cunha, Napoleon, Thompson, Bonne M., Doyle, Timothy M., McDonald, Jeffrey G., Walker, John K., Kolar, Grant R., Arnatt, Christopher Kent, Salvemini, Daniela

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Chronic Morphine-Induced Changes in Signaling at the A3 Adenosine Receptor Contribute to Morphine-Induced Hyperalgesia, Tolerance, and Withdrawal von Doyle, Timothy M., Largent-Milnes, Tally M., Chen, Zhoumou, Staikopoulos, Vasiliki, Esposito, Emanuela, Dalgarno, Rebecca, Fan, Churmy, Tosh, Dilip K., Cuzzocrea, Salvatore, Jacobson, Kenneth A., Trang, Tuan, Hutchinson, Mark R., Bennett, Gary J., Vanderah, Todd W., Salvemini, Daniela

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Chronic morphine-induced changes in signaling at the A 3 adenosine receptor contribute to morphine-induced hyperalgesia, tolerance and withdrawal von Doyle, Timothy M, Largent-Milnes, Tally Marie, Chen, Zhoumou, Staikopoulos, Vicky, Esposito, Emanuela, Delgarno, Rebecca, Fan, Churmy, Tosh, Dilip K, Cuzzocrea, Salvatore, Jacobson, Kenneth A, Trang, Tuan, Hutchinson, Mark R, Bennett, Gary J, Vanderah, Todd W, Salvemini, Daniela

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Novel Non-Opioid Based Therapeutics for Chronic Neuropathic Pain von Doyle, Timothy M, Braden, Kathryn, Harada, Caron M, Mufti, Fatma, Schafer, Rachel M, Salvemini, Daniela

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