Additive genetic effect of GCKR, G6PC2, and SLC30A8 variants on fasting glucose levels and risk of type 2 diabetes von Chen, Guanjie, Shriner, Daniel, Zhang, Jianhua, Zhou, Jie, Adikaram, Poorni, Doumatey, Ayo P, Bentley, Amy R, Adeyemo, Adebowale, Rotimi, Charles N

Volltext

The genomic landscape of African populations in health and disease von Rotimi, Charles N, Bentley, Amy R, Doumatey, Ayo P, Chen, Guanjie, Shriner, Daniel, Adeyemo, Adebowale

Volltext

Gut Microbiome Profiles Are Associated With Type 2 Diabetes in Urban Africans von Doumatey, Ayo P, Adeyemo, Adebowale, Zhou, Jie, Lei, Lin, Adebamowo, Sally N, Adebamowo, Clement, Rotimi, Charles N

Volltext

High sensitivity C-reactive protein (Hs-CRP) remains highly stable in long-term archived human serum von Doumatey, Ayo P., Zhou, Jie, Adeyemo, Adebowale, Rotimi, Charles

Volltext

Genome-wide association study of type 2 diabetes in Africa von Chen, Ji, Sun, Meng, Adeyemo, Adebowale, Pirie, Fraser, Carstensen, Tommy, Pomilla, Cristina, Doumatey, Ayo P., Chen, Guanjie, Young, Elizabeth H., Sandhu, Manjinder, Morris, Andrew P., Barroso, Inês, McCarthy, Mark I., Mahajan, Anubha, Wheeler, Eleanor, Rotimi, Charles N., Motala, Ayesha A.

Volltext

Genetic risk scores for cardiometabolic traits in sub-Saharan African populations von Ekoru, Kenneth, Adeyemo, Adebowale A, Chen, Guanjie, Doumatey, Ayo P, Zhou, Jie, Bentley, Amy R, Shriner, Daniel, Rotimi, Charles N

Volltext

Genes, environment, and African ancestry in cardiometabolic disorders von Doumatey, Ayo P., Bentley, Amy R., Akinyemi, Rufus, Olanrewaju, Timothy O., Adeyemo, Adebowale, Rotimi, Charles

Volltext

Lipidomics profiling and circulating triglyceride concentrations in sub-Saharan African individuals von Bentley, Amy R., Doumatey, Ayo P., Zhou, Jie, Lei, Lin, Meeks, Karlijn A. C., Heuston, Elisabeth F., Rotimi, Charles N., Adeyemo, Adebowale A.

Volltext

Serum fructosamine and glycemic status in the presence of the sickle cell mutation von Doumatey, Ayo P., Feron, Hermon, Ekoru, Kenneth, Zhou, Jie, Adeyemo, Adebowale, Rotimi, Charles N.

Volltext

Evolution of the primate trypanolytic factor APOL1 von Thomson, Russell, Genovese, Giulio, Canon, Chelsea, Kovacsics, Daniella, Higgins, Matthew K, Carrington, Mark, Winkler, Cheryl A, Kopp, Jeffrey, Rotimi, Charles, Adeyemo, Adebowale, Doumatey, Ayo, Ayodo, George, Alper, Seth L, Pollak, Martin R, Friedman, David J, Raper, Jayne

Volltext

Mendelian randomization study reveals a causal relationship between adiponectin and LDL cholesterol in Africans von Meeks, Karlijn A. C., Bentley, Amy R., Doumatey, Ayo P., Adeyemo, Adebowale A., Rotimi, Charles N.

Volltext

A genome-wide association study of hypertension and blood pressure in African Americans von Adeyemo, Adebowale, Gerry, Norman, Chen, Guanjie, Herbert, Alan, Doumatey, Ayo, Huang, Hanxia, Zhou, Jie, Lashley, Kerrie, Chen, Yuanxiu, Christman, Michael, Rotimi, Charles

Volltext

Genetic Basis of Obesity and Type 2 Diabetes in Africans: Impact on Precision Medicine von Doumatey, Ayo P., Ekoru, Kenneth, Adeyemo, Adebowale, Rotimi, Charles N.

Volltext

Association study in African-admixed populations across the Americas recapitulates asthma risk loci in non-African populations von Daya, Michelle, Rafaels, Nicholas, Brunetti, Tonya M., Chavan, Sameer, Levin, Albert M., Shetty, Aniket, Gignoux, Christopher R., Boorgula, Meher Preethi, Wojcik, Genevieve, Campbell, Monica, Vergara, Candelaria, Torgerson, Dara G., Ortega, Victor E., Doumatey, Ayo, Johnston, Henry Richard, Acevedo, Nathalie, Araujo, Maria Ilma, Avila, Pedro C., Belbin, Gillian, Bleecker, Eugene, Bustamante, Carlos, Caraballo, Luis, Cruz, Alvaro, Dunston, Georgia M., Eng, Celeste, Faruque, Mezbah U., Ferguson, Trevor S., Figueiredo, Camila, Ford, Jean G., Gan, Weiniu, Gourraud, Pierre-Antoine, Hansel, Nadia N., Hernandez, Ryan D., Herrera-Paz, Edwin Francisco, Jiménez, Silvia, Kenny, Eimear E., Knight-Madden, Jennifer, Kumar, Rajesh, Lange, Leslie A., Lange, Ethan M., Lizee, Antoine, Maul, Pissamai, Maul, Trevor, Mayorga, Alvaro, Meyers, Deborah, Nicolae, Dan L., O’Connor, Timothy D., Oliveira, Ricardo Riccio, Olopade, Christopher O., Olopade, Olufunmilayo, Qin, Zhaohui S., Rotimi, Charles, Vince, Nicolas, Watson, Harold, Wilks, Rainford J., Wilson, James G., Salzberg, Steven, Ober, Carole, Burchard, Esteban G., Williams, L. Keoki, Beaty, Terri H., Taub, Margaret A., Ruczinski, Ingo, Mathias, Rasika A., Barnes, Kathleen C.

Volltext

Refining genome-wide associated loci for serum uric acid in individuals with African ancestry von Chen, Guanjie, Shriner, Daniel, Doumatey, Ayo P, Zhou, Jie, Bentley, Amy R, Lei, Lin, Adeyemo, Adebowale, Rotimi, Charles N

Volltext

Mendelian randomization analyses suggest a causal role for circulating GIP and IL-1RA levels in homeostatic model assessment-derived measures of β-cell function and insulin sensiti... von Meeks, Karlijn A C, Bentley, Amy R, Assimes, Themistocles L, Franceschini, Nora, Adeyemo, Adebowale A, Rotimi, Charles N, Doumatey, Ayo P

Volltext

Multi-omics in nasal epithelium reveals three axes of dysregulation for asthma risk in the African Diaspora populations von Szczesny, Brooke, Boorgula, Meher Preethi, Chavan, Sameer, Campbell, Monica, Johnson, Randi K., Kammers, Kai, Thompson, Emma E., Cox, Madison S., Shankar, Gautam, Cox, Corey, Morin, Andréanne, Lorizio, Wendy, Daya, Michelle, Kelada, Samir N. P., Beaty, Terri H., Doumatey, Ayo P., Cruz, Alvaro A., Watson, Harold, Naureckas, Edward T., Giles, B. Louise, Arinola, Ganiyu A., Sogaolu, Olumide, Falade, Adegoke G., Hansel, Nadia N., Yang, Ivana V., Olopade, Christopher O., Rotimi, Charles N., Landis, R. Clive, Figueiredo, Camila A., Altman, Matthew C., Kenny, Eimear, Ruczinski, Ingo, Liu, Andrew H., Ober, Carole, Taub, Margaret A., Barnes, Kathleen C., Mathias, Rasika A.

Volltext

Untargeted metabolomic profiling reveals molecular signatures associated with type 2 diabetes in Nigerians von Doumatey, Ayo P, Shriner, Daniel, Zhou, Jie, Lei, Lin, Chen, Guanjie, Oluwasola-Taiwo, Omolara, Nkem, Susan, Ogundeji, Adela, Adebamowo, Sally N, Bentley, Amy R, Gouveia, Mateus H, Meeks, Karlijn A C, Adebamowo, Clement A, Adeyemo, Adebowale A, Rotimi, Charles N

Volltext

GWAS in Africans identifies novel lipids loci and demonstrates heterogenous association within Africa von Bentley, Amy R, Chen, Guanjie, Doumatey, Ayo P, Shriner, Daniel, Meeks, Karlijn A C, Gouveia, Mateus H, Ekoru, Kenneth, Zhou, Jie, Adeyemo, Adebowale, Rotimi, Charles N

Volltext

Meta-analysis of genome-wide association studies in African Americans provides insights into the genetic architecture of type 2 diabetes von Ng, Maggie C Y, Shriner, Daniel, Chen, Brian H, Li, Jiang, Chen, Wei-Min, Guo, Xiuqing, Liu, Jiankang, Bielinski, Suzette J, Yanek, Lisa R, Nalls, Michael A, Comeau, Mary E, Rasmussen-Torvik, Laura J, Jensen, Richard A, Evans, Daniel S, Sun, Yan V, An, Ping, Patel, Sanjay R, Lu, Yingchang, Long, Jirong, Armstrong, Loren L, Wagenknecht, Lynne, Yang, Lingyao, Snively, Beverly M, Palmer, Nicholette D, Mudgal, Poorva, Langefeld, Carl D, Keene, Keith L, Freedman, Barry I, Mychaleckyj, Josyf C, Nayak, Uma, Raffel, Leslie J, Goodarzi, Mark O, Chen, Y-D Ida, Taylor, Jr, Herman A, Correa, Adolfo, Sims, Mario, Couper, David, Pankow, James S, Boerwinkle, Eric, Adeyemo, Adebowale, Doumatey, Ayo, Chen, Guanjie, Mathias, Rasika A, Vaidya, Dhananjay, Singleton, Andrew B, Zonderman, Alan B, Igo, Jr, Robert P, Sedor, John R, Kabagambe, Edmond K, Siscovick, David S, McKnight, Barbara, Rice, Kenneth, Liu, Yongmei, Hsueh, Wen-Chi, Zhao, Wei, Bielak, Lawrence F, Kraja, Aldi, Province, Michael A, Bottinger, Erwin P, Gottesman, Omri, Cai, Qiuyin, Zheng, Wei, Blot, William J, Lowe, William L, Pacheco, Jennifer A, Crawford, Dana C, Grundberg, Elin, Rich, Stephen S, Hayes, M Geoffrey, Shu, Xiao-Ou, Loos, Ruth J F, Borecki, Ingrid B, Peyser, Patricia A, Cummings, Steven R, Psaty, Bruce M, Fornage, Myriam, Iyengar, Sudha K, Evans, Michele K, Becker, Diane M, Kao, W H Linda, Wilson, James G, Rotter, Jerome I, Sale, Michèle M, Liu, Simin, Rotimi, Charles N, Bowden, Donald W

Volltext