RiPP antibiotics: biosynthesis and engineering potential von Hudson, Graham A, Mitchell, Douglas A

Volltext

YcaO-Dependent Posttranslational Amide Activation: Biosynthesis, Structure, and Function von Burkhart, Brandon J., Schwalen, Christopher J., Mann, Greg, Naismith, James H., Mitchell, Douglas A.

Volltext

Biosynthesis and Chemical Applications of Thioamides von Mahanta, Nilkamal, Szantai-Kis, D. Miklos, Petersson, E. James, Mitchell, Douglas A

Volltext

Bioinformatic Expansion and Discovery of Thiopeptide Antibiotics von Schwalen, Christopher J, Hudson, Graham A, Kille, Bryce, Mitchell, Douglas A

Volltext

Cell-Free Biosynthesis to Evaluate Lasso Peptide Formation and Enzyme–Substrate Tolerance von Si, Yuanyuan, Kretsch, Ashley M, Daigh, Laura M, Burk, Mark J, Mitchell, Douglas A

Volltext

Precursor peptide-targeted mining of more than one hundred thousand genomes expands the lanthipeptide natural product family von Walker, Mark C, Eslami, Sara M, Hetrick, Kenton J, Ackenhusen, Sarah E, Mitchell, Douglas A, van der Donk, Wilfred A

Volltext

Enzymatic Reconstitution and Biosynthetic Investigation of the Lasso Peptide Fusilassin von DiCaprio, Adam J, Firouzbakht, Arash, Hudson, Graham A, Mitchell, Douglas A

Volltext

Enzymatic reconstitution of ribosomal peptide backbone thioamidation von Mahanta, Nilkamal, Liu, Andi, Dong, Shihui, Nair, Satish K., Mitchell, Douglas A.

Volltext

In Vitro Biosynthesis of the Core Scaffold of the Thiopeptide Thiomuracin von Hudson, Graham A, Zhang, Zhengan, Tietz, Jonathan I, Mitchell, Douglas A, van der Donk, Wilfred A

Volltext

Reactivity-based screening for natural product discovery von Harris, Lonnie A, Mitchell, Douglas A

Volltext

Functional interactions between posttranslationally modified amino acids of methyl-coenzyme M reductase in Methanosarcina acetivorans von Nayak, Dipti D, Liu, Andi, Agrawal, Neha, Rodriguez-Carerro, Roy, Dong, Shi-Hui, Mitchell, Douglas A, Nair, Satish K, Metcalf, William W

Volltext

Thiazole/oxazole-modified microcins: complex natural products from ribosomal templates von Melby, Joel O, Nard, Nathan J, Mitchell, Douglas A

Volltext

Genome mining unveils a class of ribosomal peptides with two amino termini von Ren, Hengqian, Dommaraju, Shravan R., Huang, Chunshuai, Cui, Haiyang, Pan, Yuwei, Nesic, Marko, Zhu, Lingyang, Sarlah, David, Mitchell, Douglas A., Zhao, Huimin

Volltext

A scalable platform to discover antimicrobials of ribosomal origin von Ayikpoe, Richard S., Shi, Chengyou, Battiste, Alexander J., Eslami, Sara M., Ramesh, Sangeetha, Simon, Max A., Bothwell, Ian R., Lee, Hyunji, Rice, Andrew J., Ren, Hengqian, Tian, Qiqi, Harris, Lonnie A., Sarksian, Raymond, Zhu, Lingyang, Frerk, Autumn M., Precord, Timothy W., van der Donk, Wilfred A., Mitchell, Douglas A., Zhao, Huimin

Volltext

RadicalSAM.org: A Resource to Interpret Sequence-Function Space and Discover New Radical SAM Enzyme Chemistry von Oberg, Nils, Precord, Timothy W, Mitchell, Douglas A, Gerlt, John A

Volltext

Post-translational thioamidation of methyl-coenzyme M reductase, a key enzyme in methanogenic and methanotrophic Archaea von Nayak, Dipti D, Mahanta, Nilkamal, Mitchell, Douglas A, Metcalf, William W

Volltext

YcaO domains use ATP to activate amide backbones during peptide cyclodehydrations von Dunbar, Kyle L, Melby, Joel O, Mitchell, Douglas A

Volltext

Discovery of a new ATP-binding motif involved in peptidic azoline biosynthesis von Dunbar, Kyle L, Chekan, Jonathan R, Cox, Courtney L, Burkhart, Brandon J, Nair, Satish K, Mitchell, Douglas A

Volltext

The genomic landscape of ribosomal peptides containing thiazole and oxazole heterocycles von Cox, Courtney L, Doroghazi, James R, Mitchell, Douglas A

Volltext

Microviridin 1777: A Toxic Chymotrypsin Inhibitor Discovered by a Metabologenomic Approach von Sieber, Simon, Grendelmeier, Simone M, Harris, Lonnie A, Mitchell, Douglas A, Gademann, Karl

Volltext