The next horizon in precision oncology: Proteogenomics to inform cancer diagnosis and treatment von Rodriguez, Henry, Zenklusen, Jean Claude, Staudt, Louis M., Doroshow, James H., Lowy, Douglas R.

Volltext

On the Design of Combination Cancer Therapy von Doroshow, James H., Simon, Richard M.

Volltext

Molecular Analysis for Therapy Choice: NCI MATCH von Conley, Barbara A, Doroshow, James H., MD

Volltext

Trapping of PARP1 and PARP2 by Clinical PARP Inhibitors von MURAI, Junko, HUANG, Shar-Yin N, BRATA DAS, Benu, RENAUD, Amelie, YIPING ZHANG, DOROSHOW, James H, JIUPING JI, TAKEDA, Shunichi, POMMIER, Yves

Volltext

TPM, FPKM, or Normalized Counts? A Comparative Study of Quantification Measures for the Analysis of RNA-seq Data from the NCI Patient-Derived Models Repository von Zhao, Yingdong, Li, Ming-Chung, Konaté, Mariam M, Chen, Li, Das, Biswajit, Karlovich, Chris, Williams, P. Mickey, Evrard, Yvonne A, Doroshow, James H, McShane, Lisa M

Volltext

Inhibiting the Activity of NADPH Oxidase in Cancer von Konaté, Mariam M, Antony, Smitha, Doroshow, James H

Volltext

Converting tabular data into images for deep learning with convolutional neural networks von Zhu, Yitan, Brettin, Thomas, Xia, Fangfang, Partin, Alexander, Shukla, Maulik, Yoo, Hyunseung, Evrard, Yvonne A., Doroshow, James H., Stevens, Rick L.

Volltext

Predicting tumor cell line response to drug pairs with deep learning von Xia, Fangfang, Shukla, Maulik, Brettin, Thomas, Garcia-Cardona, Cristina, Cohn, Judith, Allen, Jonathan E, Maslov, Sergei, Holbeck, Susan L, Doroshow, James H, Evrard, Yvonne A, Stahlberg, Eric A, Stevens, Rick L

Volltext

Analysis of Food and Drug Administration-approved anticancer agents in the NCI60 panel of human tumor cell lines von Holbeck, Susan L, Collins, Jerry M, Doroshow, James H

Volltext

Phosphorylated fraction of H2AX as a measurement for DNA damage in cancer cells and potential applications of a novel assay von Ji, Jiuping, Zhang, Yiping, Redon, Christophe E, Reinhold, William C, Chen, Alice P, Fogli, Laura K, Holbeck, Susan L, Parchment, Ralph E, Hollingshead, Melinda, Tomaszewski, Joseph E, Dudon, Quentin, Pommier, Yves, Doroshow, James H, Bonner, William M

Volltext

Putative DNA/RNA helicase Schlafen-11 (SLFN11) sensitizes cancer cells to DNA-damaging agents von Zoppoli, Gabriele, Regairaz, Marie, Leo, Elisabetta, Reinhold, William C, Varma, Sudhir, Ballestrero, Alberto, Doroshow, James H, Pommier, Yves

Volltext

Loss of 53BP1 causes PARP inhibitor resistance in Brca1-mutated mouse mammary tumors von Jaspers, Janneke E, Kersbergen, Ariena, Boon, Ute, Sol, Wendy, van Deemter, Liesbeth, Zander, Serge A, Drost, Rinske, Wientjens, Ellen, Ji, Jiuping, Aly, Amal, Doroshow, James H, Cranston, Aaron, Martin, Niall M B, Lau, Alan, O'Connor, Mark J, Ganesan, Shridar, Borst, Piet, Jonkers, Jos, Rottenberg, Sven

Volltext

Utilizing targeted cancer therapeutic agents in combination: novel approaches and urgent requirements von Doroshow, James H, Kummar, Shivanni, Chen, Helen X, Wright, John, Holbeck, Susan, Millin, Myrtle Davis, Tomaszewski, Joseph, Zweibel, James, Collins, Jerry

Volltext

DNA damage, demethylation and anticancer activity of DNA methyltransferase (DNMT) inhibitors von Laranjeira, Angelo B. A., Hollingshead, Melinda G., Nguyen, Dat, Kinders, Robert J., Doroshow, James H., Yang, Sherry X.

Volltext

ATR inhibitors VE-821 and VX-970 sensitize cancer cells to topoisomerase i inhibitors by disabling DNA replication initiation and fork elongation responses von Jossé, Rozenn, Martin, Scott E, Guha, Rajarshi, Ormanoglu, Pinar, Pfister, Thomas D, Reaper, Philip M, Barnes, Christopher S, Jones, Julie, Charlton, Peter, Pollard, John R, Morris, Joel, Doroshow, James H, Pommier, Yves

Volltext

NADPH oxidase 1 supports proliferation of colon cancer cells by modulating reactive oxygen species-dependent signal transduction von Juhasz, Agnes, Markel, Susan, Gaur, Shikha, Liu, Han, Lu, Jiamo, Jiang, Guojian, Wu, Xiwei, Antony, Smitha, Wu, Yongzhong, Melillo, Giovanni, Meitzler, Jennifer L., Haines, Diana C., Butcher, Donna, Roy, Krishnendu, Doroshow, James H.

Volltext

Advances in using PARP inhibitors to treat cancer von Kummar, Shivaani, Chen, Alice, Parchment, Ralph E, Kinders, Robert J, Ji, Jay, Tomaszewski, Joseph E, Doroshow, James H

Volltext

Cediranib for Metastatic Alveolar Soft Part Sarcoma von KUMMAR, Shivaani, ALLEN, Deborah, SIMON, Richard, STEINBERG, Seth M, DOROSHOW, James H, HELMAN, Lee, MONKS, Anne, POLLEY, Eric C, HOSE, Curtis D, IVY, S. Percy, TURKBEY, Ismail B, LAWRENCE, Scott, KINDERS, Robert J, CHOYKE, Peter

Volltext

Learning curves for drug response prediction in cancer cell lines von Partin, Alexander, Brettin, Thomas, Evrard, Yvonne A, Zhu, Yitan, Yoo, Hyunseung, Xia, Fangfang, Jiang, Songhao, Clyde, Austin, Shukla, Maulik, Fonstein, Michael, Doroshow, James H, Stevens, Rick L

Volltext

Overcoming Resistance to Targeted Anticancer Drugs von Doroshow, James H

Volltext