Optimized Clostridium-Directed Enzyme Prodrug Therapy Improves the Antitumor Activity of the Novel DNA Cross-Linking Agent PR-104 von LIU, Shie-Chau, AHN, G-One, KIOI, Mitomu, DONE, Mary-Jo, PATTERSON, Adam V, BROWN, J. Martin

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Association of reactive oxygen species levels and radioresistance in cancer stem cells von Diehn, Maximilian, Cho, Robert W., Lobo, Neethan A., Kalisky, Tomer, Dorie, Mary Jo, Kulp, Angela N., Qian, Dalong, Lam, Jessica S., Ailles, Laurie E., Wong, Manzhi, Joshua, Benzion, Kaplan, Michael J., Wapnir, Irene, Dirbas, Frederick M., Somlo, George, Garberoglio, Carlos, Paz, Benjamin, Shen, Jeannie, Lau, Sean K., Quake, Stephen R., Brown, J. Martin, Weissman, Irving L., Clarke, Michael F.

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Inhibition of Mac-1 (CD11b/CD18) enhances tumor response to radiation by reducing myeloid cell recruitment von Ahn, G. One, Tseng, Diane, Liao, Cho-Hwa, Dorie, Mary Jo, Czechowicz, Agnieszka, Brown, J. Martin

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ATR/ATM Targets Are Phosphorylated by ATR in Response to Hypoxia and ATM in Response to Reoxygenation von Hammond, Ester M, Dorie, Mary Jo, Giaccia, Amato J

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Hypoxia Links ATR and p53 through Replication Arrest von Hammond, Ester M., Denko, Nicholas C., Dorie, Mary Jo, Abraham, Robert T., Giaccia, Amato J.

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Renal Oxygenation Suppresses VHL Loss-Induced Senescence That Is Caused by Increased Sensitivity to Oxidative Stress von Welford, Scott M., Dorie, Mary Jo, Li, Xiaofeng, Haase, Volker H., Giaccia, Amato J.

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Inhibition of ATR leads to increased sensitivity to hypoxia/reoxygenation von HAMMOND, Ester M, DORIE, Mary Jo, GIACCIA, Amato J

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Pharmacokinetic/Pharmacodynamic Modeling Identifies SN30000 and SN29751 as Tirapazamine Analogues with Improved Tissue Penetration and Hypoxic Cell Killing in Tumors von HICKS, Kevin O, SIIM, Bronwyn G, DENNY, William A, HAY, Michael P, WILSON, William R, JAISWAL, Jagdish K, PRUIJN, Frederik B, FRASER, Annie M, PATEL, Rita, HOGG, Alison, SARATH LIYANAGE, H. D, JO DORIE, Mary, BROWN, J. Martin

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DNA Damage during Reoxygenation Elicits a Chk2-Dependent Checkpoint Response von Freiberg, Rachel A., Hammond, Ester M., Dorie, Mary Jo, Welford, Scott M., Giaccia, Amato J.

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Mature results from a randomized Phase II trial of cisplatin plus 5‐fluorouracil and radiotherapy with or without tirapazamine in patients with resectable Stage IV head and neck sq... von Le, Quynh‐Thu, Taira, Al, Budenz, Sherie, Jo Dorie, Mary, Goffinet, Don R., Fee, Willard E., Goode, Richard, Bloch, Daniel, Koong, Albert, Martin Brown, J., Pinto, Harlan A.

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Comparison of the comet assay and the oxygen microelectrode for measuring tumor oxygenation in head-and-neck cancer patients von Le, Quynh-Thu, Kovacs, Mary S, Dorie, Mary Jo, Koong, Albert, Terris, David J, Pinto, Harlan A, Goffinet, Don R, Nowels, Kent, Bloch, Dan, Brown, J.Martin

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DNA Damage Measured by the Comet Assay in Head and Neck Cancer Patients Treated with Tirapazamine von Dorie, Mary Jo, Kovacs, Mary S., Gabalski, Edward C., Adam, Markus, Le, Quynh-T, Bloch, Daniel A., Pinto, Harlan A., Terris, David J., Brown, J. Martin

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Optimized Clostridia-Directed Enzyme Prodrug Therapy Improves the Antitumor Activity of the Novel DNA-Cross-Linking Agent PR-104 von Liu, Shie-Chau, Ahn, G-One, Kioi, Mitomu, Dorie, Mary-Jo, Patterson, Adam V., Brown, J. Martin

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128 von Dorie, Mary Jo, Ahn, G-one, Menke, Douglas, Douglas, Rachelle, Siim, Bronwyn, Patterson, Adam, Wilson, William, Brown, Martin

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Oxygen tension measurements of tumors growing in mice von Adam, Markus F, Dorie, Mary Jo, Brown, J.Martin

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128: Prediction of Antitumor Activity of PR-104, a New Hypoxia Activated Mustard, Using Measurements of DNA Interstrand Crosslinks by the Comet Assay von Dorie, Mary Jo, Ahn, G-one, Menke, Douglas, Douglas, Rachelle, Siim, Bronwyn, Patterson, Adam, Wilson, William, Brown, Martin

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Modification of the antitumor activity of chemotherapeutic drugs by the hypoxic cytotoxic agent tirapazamine von DORIE, M. J, BROWN, J. M

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Tirapazamine-induced cytotoxicity and DNA damage in transplanted tumors : Relationship to tumor hypoxia von SIIM, B. G, MENKE, D. R, DORIE, M. J, BROWN, J. M

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Mature results from a randomized phase II trial of cisplatin plus 5-fluorouracil and radiotherapy with or without tirapazamine in patients with resectable stage IV p ead and neck s... von LE, Quynh-Thu, TAIRA, Al, PINTO, Harlan A, BUDENZ, Sherie, DORIE, Mary Jo, GOFFINET, Don R, FEE, Willard E, GOODE, Richard, BLOCH, Daniel, KOONG, Albert, BROWN, J. Martin

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Mitochondrial dysfunction after aerobic exposure to the hypoxic cytotoxin tirapazamine von WOUTERS, Bradly G, DELAHOUSSAYE, Yvette M, EVANS, James W, BIRRELL, Geoffrey W, DORIE, Mary Jo, JINGLI WANG, MACDERMED, Dhara, CHIU, Roland K, BROWN, J. Martin

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