Synthesis and antiproliferative activity of sulfonamide-based peptidomimetic calpain inhibitors von Donkor, Isaac O., Xu, Jin, Liu, Jiuyu, Cameron, Keyuna

Volltext

Peptidomimetic Probes and Molecular Modeling Suggest That Alzheimer's γ-Secretase Is an Intramembrane-Cleaving Aspartyl Protease von Wolfe, Michael S, Xia, Weiming, Moore, Chad L, Leatherwood, Dartha D, Ostaszewski, Beth, Rahmati, Talat, Donkor, Isaac O, Selkoe, Dennis J

Volltext

Structural Basis for the Potent Calpain Inhibitory Activity of Peptidyl α-Ketoacids von Donkor, Isaac O, Assefa, Haregewein, Liu, Jiuyu

Volltext

Synthesis and calpain inhibitory activity of peptidomimetic compounds with constrained amino acids at the P2 position von Donkor, Isaac O., Korukonda, Rajani

Volltext

A Substrate-Based Difluoro Ketone Selectively Inhibits Alzheimer's γ-Secretase Activity von Wolfe, Michael S, Citron, Martin, Diehl, Thekla S, Xia, Weiming, Donkor, Isaac O, Selkoe, Dennis J

Volltext

Synthesis and DHFR inhibitory activity of a series of 6-substituted-2,4-diaminothieno[2,3- d]pyrimidines von Donkor, Isaac O, Li, Hui, Queener, Sherry F

Volltext

Trypanocidal Activity of Conformationally Restricted Pentamidine Congeners von Donkor, Isaac O, Huang, Tien L, Tao, Bin, Rattendi, Donna, Lane, Schennella, Vargas, Marc, Goldberg, Burt, Bacchi, Cyrus

Volltext

Trypanocidal activity of piperazine-linked bisbenzamidines and bisbenzamidoxime, an orally active prodrug von Huang, Tien L, Bacchi, Cyrus J, Kode, Nageswara R, Zhang, Qiang, Wang, Guangdi, Yartlet, Nigel, Rattendi, Donna, Londono, Indira, Mazumder, Lakshman, Vanden Eynde, Jean Jacques, Mayence, Annie, Donkor, Isaac O

Volltext

Novel piperazine induces apoptosis in U937 cells von Sampson, 3rd, Josiah J, Donkor, Isaac O, Huang, Tien L, Adunyah, Samuel E

Volltext

Apoptosis induced by novel aldehyde calpain inhibitors in human tumor cell lines von NA GUAN, KORUKONDA, Rajani, HURH, Eunju, SCHMITTGEN, Thomas D, DONKOR, Isaac O, DALTON, James T

Volltext

A novel series of urea-based peptidomimetic calpain inhibitors von Sanders, M. Lee, Donkor, Isaac O.

Volltext

Significance of hydrogen bonding at the S1' subsite of calpain I von DONKOR, Isaac O, XIAOZHANG ZHENG, JIE HAN, LACY, Calvin, MILLER, Duane D

Volltext

Anti-plasmodial and anti-leishmanial activity of conformationally restricted pentamidine congeners von Huang, Tien L., Vanden Eynde, Jean Jacques, Mayence, Annie, Donkor, Isaac O., Khan, Shabana I., Tekwani, Babu L.

Volltext

Synthesis, Calpain Inhibitory Activity, and Cytotoxicity of P2-Substituted Proline and Thiaproline Peptidyl Aldehydes and Peptidyl α-Ketoamides von Korukonda, Rajani, Guan, Na, Dalton, James T, Liu, Jiuyu, Donkor, Isaac O

Volltext

Peptidyl aldehyde inhibitors of calpain incorporating P2-Proline mimetics von DONKOR, Isaac O, KORUKONDA, Rajani, HUANG, Tien L, LECOUR, Louis JR

Volltext

Design, Synthesis, Molecular Modeling Studies, and Calpain Inhibitory Activity of Novel α-Ketoamides Incorporating Polar Residues at the P1‘-Position von Donkor, Isaac O, Han, Jie, Zheng, Xiaozhang

Volltext

Trypanocidal activity of dicationic compounds related to pentamidine von Donkor, Isaac O, Assefa, Haregewein, Rattendi, Donna, Lane, Schennella, Vargas, Marc, Goldberg, Burt, Bacchi, Cyrus

Volltext

N, N′-Bis[4-( N-alkylamidino)phenyl]homopiperazines as anti- Pneumocystis carinii agents von Huang, Tien L, Tao, Bin, Quarshie, Yvonne, Queener, Sherry F, Donkor, Isaac O

Volltext

Synthesis and anti- Pneumocystis carinii activity of conformationally restricted analogues of pentamidine von Tao, Bin, Huang, Tien L, Zhang, Qian, Jackson, Latasha, Queener, Sherry F, Donkor, Isaac O

Volltext

Synthesis and calpain inhibitory activity of α-ketoamides with 2,3-methanoleucine stereoisomers at the P2 position von DONKOR, Isaac O, XIAOZHANG ZHENG, MILLER, Duane D

Volltext