Comprehensive Analysis of the Human SH3 Domain Family Reveals a Wide Variety of Non-canonical Specificities von Teyra, Joan, Huang, Haiming, Jain, Shobhit, Guan, Xinyu, Dong, Aiping, Liu, Yanli, Tempel, Wolfram, Min, Jinrong, Tong, Yufeng, Kim, Philip M., Bader, Gary D., Sidhu, Sachdev S.

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The structural basis for selective binding of non-methylated CpG islands by the CFP1 CXXC domain von Min, Jinrong, Xu, Chao, Bian, Chuanbing, Lam, Robert, Dong, Aiping

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Structural insights into trans-histone regulation of H3K4 methylation by unique histone H4 binding of MLL3/4 von Liu, Yanli, Qin, Su, Chen, Tsai-Yu, Lei, Ming, Dhar, Shilpa S., Ho, Jolene Caifeng, Dong, Aiping, Loppnau, Peter, Li, Yanjun, Lee, Min Gyu, Min, Jinrong

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Structure and Biochemical Functions of SIRT6 von Pan, Patricia W., Feldman, Jessica L., Devries, Mark K., Dong, Aiping, Edwards, Aled M., Denu, John M.

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A chemical probe selectively inhibits G9a and GLP methyltransferase activity in cells von Vedadi, Masoud, Barsyte-Lovejoy, Dalia, Liu, Feng, Rival-Gervier, Sylvie, Allali-Hassani, Abdellah, Labrie, Viviane, Wigle, Tim J, DiMaggio, Peter A, Wasney, Gregory A, Siarheyeva, Alena, Dong, Aiping, Tempel, Wolfram, Wang, Sun-Chong, Chen, Xin, Chau, Irene, Mangano, Thomas J, Huang, Xi-ping, Simpson, Catherine D, Pattenden, Samantha G, Norris, Jacqueline L, Kireev, Dmitri B, Tripathy, Ashutosh, Edwards, Aled, Roth, Bryan L, Janzen, William P, Garcia, Benjamin A, Petronis, Arturas, Ellis, James, Brown, Peter J, Frye, Stephen V, Arrowsmith, Cheryl H, Jin, Jian

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Structure of the catalytic domain of EZH2 reveals conformational plasticity in cofactor and substrate binding sites and explains oncogenic mutations von Wu, Hong, Zeng, Hong, Dong, Aiping, Li, Fengling, He, Hao, Senisterra, Guillermo, Seitova, Alma, Duan, Shili, Brown, Peter J, Vedadi, Masoud, Arrowsmith, Cheryl H, Schapira, Matthieu

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(R)-PFI-2 is a potent and selective inhibitor of SETD7 methyltransferase activity in cells von Barsyte-Lovejoy, Dalia, Li, Fengling, Oudhoff, Menno J., Tatlock, John H., Dong, Aiping, Zeng, Hong, Wu, Hong, Freeman, Spencer A., Schapira, Matthieu, Senisterra, Guillermo A., Kuznetsova, Ekaterina, Marcellus, Richard, Allali-Hassani, Abdellah, Kennedy, Steven, Lambert, Jean-Philippe, Couzens, Amber L., Aman, Ahmed, Gingras, Anne-Claude, Al-Awar, Rima, Fish, Paul V., Gerstenberger, Brian S., Roberts, Lee, Benn, Caroline L., Grimley, Rachel L., Braam, Mitchell J. S., Rossi, Fabio M. V., Sudol, Marius, Brown, Peter J., Bunnage, Mark E., Owen, Dafydd R., Zaph, Colby, Vedadi, Masoud, Arrowsmith, Cheryl H.

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Chemical basis for the recognition of trimethyllysine by epigenetic reader proteins von Kamps, Jos J.A.G., Huang, Jiaxin, Poater, Jordi, Xu, Chao, Pieters, Bas J.G.E., Dong, Aiping, Min, Jinrong, Sherman, Woody, Beuming, Thijs, Matthias Bickelhaupt, F., Li, Haitao, Mecinović, Jasmin

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Structural basis for the regulatory role of the PPxY motifs in the thioredoxin-interacting protein TXNIP von Liu, Yanli, Lau, Johnathan, Li, Weiguo, Tempel, Wolfram, Li, Li, Dong, Aiping, Narula, Ashrut, Qin, Su, Min, Jinrong

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Molecular Basis for the Regulation of the H3K4 Methyltransferase Activity of PRDM9 von Wu, Hong, Mathioudakis, Nikolas, Diagouraga, Boubou, Dong, Aiping, Dombrovski, Ludmila, Baudat, Frédéric, Cusack, Stephen, de Massy, Bernard, Kadlec, Jan

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Structural Basis of the Recruitment of Ubiquitin-specific Protease USP15 by Spliceosome Recycling Factor SART3 von Zhang, Qi, Harding, Rachel, Hou, Feng, Dong, Aiping, Walker, John R., Bteich, Joseph, Tong, Yufeng

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Discovery of a 2,4-Diamino-7-aminoalkoxyquinazoline as a Potent and Selective Inhibitor of Histone Lysine Methyltransferase G9a von Liu, Feng, Chen, Xin, Allali-Hassani, Abdellah, Quinn, Amy M, Wasney, Gregory A, Dong, Aiping, Barsyte, Dalia, Kozieradzki, Ivona, Senisterra, Guillermo, Chau, Irene, Siarheyeva, Alena, Kireev, Dmitri B, Jadhav, Ajit, Herold, J. Martin, Frye, Stephen V, Arrowsmith, Cheryl H, Brown, Peter J, Simeonov, Anton, Vedadi, Masoud, Jin, Jian

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Protein Lysine Methyltransferase G9a Inhibitors: Design, Synthesis, and Structure Activity Relationships of 2,4-Diamino-7-aminoalkoxy-quinazolines von Liu, Feng, Chen, Xin, Allali-Hassani, Abdellah, Quinn, Amy M, Wigle, Tim J, Wasney, Gregory A, Dong, Aiping, Senisterra, Guillermo, Chau, Irene, Siarheyeva, Alena, Norris, Jacqueline L, Kireev, Dmitri B, Jadhav, Ajit, Herold, J. Martin, Janzen, William P, Arrowsmith, Cheryl H, Frye, Stephen V, Brown, Peter J, Simeonov, Anton, Vedadi, Masoud, Jin, Jian

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Structural and functional consequences of the STAT5BN642H driver mutation von de Araujo, Elvin D., Erdogan, Fettah, Neubauer, Heidi A., Meneksedag-Erol, Deniz, Manaswiyoungkul, Pimyupa, Eram, Mohammad S., Seo, Hyuk-Soo, Qadree, Abdul K., Israelian, Johan, Orlova, Anna, Suske, Tobias, Pham, Ha T. T., Boersma, Auke, Tangermann, Simone, Kenner, Lukas, Rülicke, Thomas, Dong, Aiping, Ravichandran, Manimekalai, Brown, Peter J., Audette, Gerald F., Rauscher, Sarah, Dhe-Paganon, Sirano, Moriggl, Richard, Gunning, Patrick T.

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Entropy-driven binding of opioid peptides induces a large domain motion in human dipeptidyl peptidase III von Bezerra, Gustavo A., Dobrovetsky, Elena, Viertlmayr, Roland, Dong, Aiping, Binter, Alexandra, Abramić, Marija, Macheroux, Peter, Dhe-Paganon, Sirano, Gruber, Karl

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A chemical probe of CARM1 alters epigenetic plasticity against breast cancer cell invasion von Cai, Xiao-Chuan, Zhang, Tuo, Kim, Eui-Jun, Jiang, Ming, Wang, Ke, Wang, Junyi, Chen, Shi, Zhang, Nawei, Wu, Hong, Li, Fengling, Dela Seña, Carlo C, Zeng, Hong, Vivcharuk, Victor, Niu, Xiang, Zheng, Weihong, Lee, Jonghan P, Chen, Yuling, Barsyte, Dalia, Szewczyk, Magda, Hajian, Taraneh, Ibáñez, Glorymar, Dong, Aiping, Dombrovski, Ludmila, Zhang, Zhenyu, Deng, Haiteng, Min, Jinrong, Arrowsmith, Cheryl H, Mazutis, Linas, Shi, Lei, Vedadi, Masoud, Brown, Peter J, Xiang, Jenny, Qin, Li-Xuan, Xu, Wei, Luo, Minkui

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Structural and chemical profiling of the human cytosolic sulfotransferases von Allali-Hassani, Abdellah, Pan, Patricia W, Dombrovski, Ludmila, Najmanovich, Rafael, Tempel, Wolfram, Dong, Aiping, Loppnau, Peter, Martin, Fernando, Thornton, Janet, Thonton, Janet, Edwards, Aled M, Bochkarev, Alexey, Plotnikov, Alexander N, Vedadi, Masoud, Arrowsmith, Cheryl H

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In situ proteolysis for protein crystallization and structure determination von Edwards, Aled M, Dong, Aiping, Xu, Xiaohui

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Methylation-state-specific recognition of histones by the MBT repeat protein L3MBTL2 von Guo, Yahong, Nady, Nataliya, Qi, Chao, Allali-Hassani, Abdellah, Zhu, Haizhong, Pan, Patricia, Adams-Cioaba, Melanie A, Amaya, Maria F, Dong, Aiping, Vedadi, Masoud, Schapira, Matthieu, Read, Randy J, Arrowsmith, Cheryl H, Min, Jinrong

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Genome-scale protein expression and structural biology of Plasmodium falciparum and related Apicomplexan organisms von Vedadi, Masoud, Lew, Jocelyne, Artz, Jennifer, Amani, Mehrnaz, Zhao, Yong, Dong, Aiping, Wasney, Gregory A., Gao, Mian, Hills, Tanya, Brokx, Stephen, Qiu, Wei, Sharma, Sujata, Diassiti, Angelina, Alam, Zahoor, Melone, Michelle, Mulichak, Anne, Wernimont, Amy, Bray, James, Loppnau, Peter, Plotnikova, Olga, Newberry, Kate, Sundararajan, Emayavaram, Houston, Simon, Walker, John, Tempel, Wolfram, Bochkarev, Alexey, Kozieradzki, Ivona, Edwards, Aled, Arrowsmith, Cheryl, Roos, David, Kain, Kevin, Hui, Raymond

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