Spatiotemporal Regulation of Epithelial-Mesenchymal Transition Is Essential for Squamous Cell Carcinoma Metastasis von Tsai, Jeff H., Donaher, Joana Liu, Murphy, Danielle A., Chau, Sandra, Yang, Jing

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Integrin-β4 identifies cancer stem cell-enriched populations of partially mesenchymal carcinoma cells von Bierie, Brian, Pierce, Sarah E., Kroeger, Cornelia, Stover, Daniel G., Pattabiraman, Diwakar R., Thiru, Prathapan, Donaher, Joana Liu, Reinhardt, Ferenc, Chaffer, Christine L., Keckesova, Zuzana, Weinberg, Robert A.

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Slug and Sox9 Cooperatively Determine the Mammary Stem Cell State von Guo, Wenjun, Keckesova, Zuzana, Donaher, Joana Liu, Shibue, Tsukasa, Tischler, Verena, Reinhardt, Ferenc, Itzkovitz, Shalev, Noske, Aurelia, Zürrer-Härdi, Ursina, Bell, George, Tam, Wai Leong, Mani, Sendurai A., van Oudenaarden, Alexander, Weinberg, Robert A.

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Genome-wide CRISPR screen identifies PRC2 and KMT2D-COMPASS as regulators of distinct EMT trajectories that contribute differentially to metastasis von Zhang, Yun, Donaher, Joana Liu, Das, Sunny, Li, Xin, Reinhardt, Ferenc, Krall, Jordan A., Lambert, Arthur W., Thiru, Prathapan, Keys, Heather R., Khan, Mehreen, Hofree, Matan, Wilson, Molly M., Yedier-Bayram, Ozlem, Lack, Nathan A., Onder, Tamer T., Bagci-Onder, Tugba, Tyler, Michael, Tirosh, Itay, Regev, Aviv, Lees, Jacqueline A., Weinberg, Robert A.

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ΔNp63/p73 drive metastatic colonization by controlling a regenerative epithelial stem cell program in quasi-mesenchymal cancer stem cells von Lambert, Arthur W., Fiore, Christopher, Chutake, Yogesh, Verhaar, Elisha R., Strasser, Patrick C., Chen, Mei Wei, Farouq, Daneyal, Das, Sunny, Li, Xin, Eaton, Elinor Ng, Zhang, Yun, Liu Donaher, Joana, Engstrom, Ian, Reinhardt, Ferenc, Yuan, Bingbing, Gupta, Sumeet, Wollison, Bruce, Eaton, Matthew, Bierie, Brian, Carulli, John, Olson, Eric R., Guenther, Matthew G., Weinberg, Robert A.

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Twist, a Master Regulator of Morphogenesis, Plays an Essential Role in Tumor Metastasis von Yang, Jing, Mani, Sendurai A, Donaher, Joana Liu, Ramaswamy, Sridhar, Itzykson, Raphael A, Come, Christophe, Savagner, Pierre, Gitelman, Inna, Richardson, Andrea, Weinberg, Robert A

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Growth-Inhibitory and Tumor- Suppressive Functions of p53 Depend on Its Repression of CD44 Expression von Godar, Samuel, Ince, Tan A., Bell, George W., Feldser, David, Donaher, Joana Liu, Bergh, Jonas, Liu, Anne, Miu, Kevin, Watnick, Randolph S., Reinhardt, Ferenc, McAllister, Sandra S., Jacks, Tyler, Weinberg, Robert A.

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Human breast cancer cells generated by oncogenic transformation of primary mammary epithelial cells von Elenbaas, B, Spirio, L, Koerner, F, Fleming, M D, Zimonjic, D B, Donaher, J L, Popescu, N C, Hahn, W C, Weinberg, R A

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LACTB is a tumour suppressor that modulates lipid metabolism and cell state von Keckesova, Zuzana, Donaher, Joana Liu, De Cock, Jasmine, Freinkman, Elizaveta, Lingrell, Susanne, Bachovchin, Daniel A., Bierie, Brian, Tischler, Verena, Noske, Aurelia, Okondo, Marian C., Reinhardt, Ferenc, Thiru, Prathapan, Golub, Todd R., Vance, Jean E., Weinberg, Robert A.

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Abstract PR05: Loss of PRC2 or KMT2D-COMPASS generates two quasi-mesenchymal cell states with distinct metastatic abilities von Zhang, Yun, Donaher, Joana Liu, Das, Sunny, Li, Xin, Reinhardt, Ferenc, Krall, Jordan A., Lambert, Arthur W., Thiru, Prathapan, Keys, Heather R., Khan, Mehreen, Hofree, Matan, Wilson, Molly M., Yedier-Bayram, Ozlem, Lack, Nathan A., Onder, Tamer T., Bagci-Onder, Tugba, Tyler, Michael, Tirosh, Itay, Regev, Aviv, Lees, Jacqueline, Weinberg, Robert A.

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Integrin-[alpha]4 identifies cancer stem cell-enriched populations of partially mesenchymal carcinoma cells von Bierie, Brian, Pierce, Sarah E, Kroeger, Cornelia, Stover, Daniel G, Pattabiraman, Diwakar R, Thiru, Prathapan, Donaher, Joana Liu, Reinhardt, Ferenc, Chaffer, Christine L, Keckesova, Zuzana, Weinberg, Robert A

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LACTB is a tumour suppressor that modulates lipid metabolism and cell state von Keckesova, Zuzana, Donaher, Joana Liu, De Cock, Jasmine, Freinkman, Elizaveta, Lingrell, Susanne, Bachovchin, Daniel A, Bierie, Brian, Tischler, Verena, Noske, Aurelia, Okondo, Marian C, Reinhardt, Ferenc, Thiru, Prathapan, Golub, Todd R, Vance, Jean E, Weinberg, Robert A

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Abstract B48: Spatiotemporal regulation of epithelial-mesenchymal transition is essential for carcinoma metastasis von Tsai, Jeff H., Donaher, Joana Liu, Murphy, Danielle A., Chau, Sandra, Yang, Jing

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Cyclin D2 is an FSH-responsive gene involved in gonadal cell proliferation and oncogenesis von Sicinski, Piotr, Donaher, Joana Liu, Geng, Yan, Parker, Susan B., Gardner, Humphrey, Park, Mary Y., Robker, Rebecca L, Richards, JoAnne S., McGinnis, Lynda K., Biggers, John D., Eppig, John J., Bronson, Roderick T., Elledge, Stephen J., Weinberg, Robert A.

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AIB1 enhances estrogen-dependent induction of cyclin D1 expression von PLANAS-SILVA, Maricarmen D, YONGFENG SHANG, DONAHER, Joana Liu, BROWN, Myles, WEINBERG, Robert A

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Slug and Sox9 cooperatively determine the mammary stem cell state von Guo, Wenjun, Keckesova, Zuzana, Donaher, Joana Liu, Shibue, Tsukasa, Tischler, Verena, Reinhardt, Ferenc, Itzkovitz, Shalev, Noske, Aurelia, Zürrer-Härdi, Ursina, Bell, George, Tam, Wai Leong, Mani, Sendurai A, van Oudenaarden, Alexander, Weinberg, Robert A

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Cyclin D1 provides a link between development and oncogenesis in the retina and breast von Sicinski, Piotr, Donaher, Joana Liu, Parker, Susan B., Li, Tiansen, Fazeli, Amin, Gardner, Humphrey, Haslam, Sandra Z., Bronson, Roderick T., Elledge, Stephen J., Weinberg, Robert A.

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Functional activity of ectopically expressed estrogen receptor is not sufficient for estrogen-mediated cyclin D1 expression von PLANAS-SILVA, M. D, DONAHER, J. L, WEINBERG, R. A

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Human breast cancer cells generated by oncogenic transformation of primary mammary epithelial cells von Elenbaas, Brian, Spirio, Lisa, Koerner, Frederick, Fleming, Mark D, Zimonjic, Drazen B, Donaher, Joana Liu, Popescu, Nicholas C, Hahn, William C, Weinberg, Robert A

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Cyclin D1 Provides a Link Between Development and Oncogenesis in the Retina and Breast von Sicinski, Piotr, Donaher, Joana Liu, Parker, Susan B, Li, Tiansen, Fazeli, Amin, Gardner, Humphrey, Haslam, Sandra Z, Bronson, Roderick T, Elledge, Stephen, Weinberg, Robert A

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