Synthesis of Amino Acid Cofactor in Cysteine Dioxygenase Is Regulated by Substrate and Represents a Novel Post-translational Regulation of Activity von Dominy, John E., Hwang, Jesse, Guo, Stephanie, Hirschberger, Lawrence L., Zhang, Sheng, Stipanuk, Martha H.

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Glycine Decarboxylase Cleaves a “Malignant” Metabolic Path to Promote Tumor Initiation von Dominy, John E., Vazquez, Francisca, Puigserver, Pere

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The cAMP/PKA Pathway Rapidly Activates SIRT1 to Promote Fatty Acid Oxidation Independently of Changes in NAD von Gerhart-Hines, Zachary, Dominy, John E., Blättler, Sharon M., Jedrychowski, Mark P., Banks, Alexander S., Lim, Ji-Hong, Chim, Helen, Gygi, Steven P., Puigserver, Pere

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The Deacetylase Sirt6 Activates the Acetyltransferase GCN5 and Suppresses Hepatic Gluconeogenesis von Dominy, John E., Lee, Yoonjin, Jedrychowski, Mark P., Chim, Helen, Jurczak, Michael J., Camporez, Joao Paulo, Ruan, Hai-Bin, Feldman, Jessica, Pierce, Kerry, Mostoslavsky, Raul, Denu, John M., Clish, Clary B., Yang, Xiaoyong, Shulman, Gerald I., Gygi, Steven P., Puigserver, Pere

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The sirtuin family's role in aging and age-associated pathologies von Hall, Jessica A, Dominy, John E, Lee, Yoonjin, Puigserver, Pere

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Nuclear FoxO1 inflames insulin resistance von Dominy, John E, Puigserver, Pere

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Mammalian Cysteine Metabolism: New Insights into Regulation of Cysteine Metabolism von Stipanuk, Martha H, Dominy, John E. Jr, Lee, Jeong-In, Coloso, Relicardo M

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Discovery and Characterization of a Second Mammalian Thiol Dioxygenase, Cysteamine Dioxygenase von Dominy, John E., Simmons, Chad R., Hirschberger, Lawrence L., Hwang, Jesse, Coloso, Relicardo M., Stipanuk, Martha H.

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Cyclin D1–Cdk4 controls glucose metabolism independently of cell cycle progression von Lee, Yoonjin, Dominy, John E., Choi, Yoon Jong, Jurczak, Michael, Tolliday, Nicola, Camporez, Joao Paulo, Chim, Helen, Lim, Ji-Hong, Ruan, Hai-Bin, Yang, Xiaoyong, Vazquez, Francisca, Sicinski, Piotr, Shulman, Gerald I., Puigserver, Pere

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Thiol dioxygenases: unique families of cupin proteins von Stipanuk, Martha H, Simmons, Chad R, Andrew Karplus, P, Dominy, John E. Jr

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HepG2/C3A cells respond to cysteine deprivation by induction of the amino acid deprivation/integrated stress response pathway von Lee, Jeong-In, Dominy, John E., Jr, Sikalidis, Angelos K, Hirschberger, Lawrence L, Wang, Wei, Stipanuk, Martha H

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Overexpression of cysteine dioxygenase reduces intracellular cysteine and glutathione pools in HepG2/C3A cells von Dominy, John E., Jr, Hwang, Jesse, Stipanuk, Martha H

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Mitochondrial biogenesis through activation of nuclear signaling proteins von Dominy, John E, Puigserver, Pere

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Identification and Characterization of Bacterial Cysteine Dioxygenases: a New Route of Cysteine Degradation for Eubacteria von DOMINY, John E, SIMMONS, Chad R, KARPLUS, P. Andrew, GEHRING, Amy M, STIPANUK, Martha H

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A Putative Fe2+-Bound Persulfenate Intermediate in Cysteine Dioxygenase von Simmons, Chad R, Krishnamoorthy, Kalyanaraman, Granett, Spencer L, Schuller, David J, Dominy, John E, Begley, Tadhg P, Stipanuk, Martha H, Karplus, P. Andrew

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Genetic inhibition of hepatic acetyl-CoA carboxylase activity increases liver fat and alters global protein acetylation von Chow, Jenny D.Y, Lawrence, Robert T, Healy, Marin E, Dominy, John E, Liao, Jason A, Breen, David S, Byrne, Frances L, Kenwood, Brandon M, Lackner, Carolin, Okutsu, Saeko, Mas, Valeria R, Caldwell, Stephen H, Tomsig, Jose L, Cooney, Gregory J, Puigserver, Pere B, Turner, Nigel, James, David E, Villén, Judit, Hoehn, Kyle L

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Regulation of cysteine dioxygenase degradation is mediated by intracellular cysteine levels and the ubiquitin-26 S proteasome system in the living rat von Dominy, Jr, John E, Hirschberger, Lawrence L, Coloso, Relicardo M, Stipanuk, Martha H

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Oleic Acid Stimulates Complete Oxidation of Fatty Acids through Protein Kinase A-dependent Activation of SIRT1-PGC1α Complex von Lim, Ji-Hong, Gerhart-Hines, Zachary, Dominy, John E., Lee, Yoonjin, Kim, Sungjin, Tabata, Mitsuhisa, Xiang, Yang K., Puigserver, Pere

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Selective Chemical Inhibition of PGC-1α Gluconeogenic Activity Ameliorates Type 2 Diabetes von Sharabi, Kfir, Lin, Hua, Tavares, Clint D.J., Dominy, John E., Camporez, Joao Paulo, Perry, Rachel J., Schilling, Roger, Rines, Amy K., Lee, Jaemin, Hickey, Marc, Bennion, Melissa, Palmer, Michelle, Nag, Partha P., Bittker, Joshua A., Perez, José, Jedrychowski, Mark P., Ozcan, Umut, Gygi, Steve P., Kamenecka, Theodore M., Shulman, Gerald I., Schreiber, Stuart L., Griffin, Patrick R., Puigserver, Pere

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New Roles for Cysteine and Transsulfuration Enzymes: Production of H2S, A Neuromodulator and Smooth Muscle Relaxant von Dominy, John E., Stipanuk, Martha H.

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