Pyrido[2,3-d]pyrimidines: Discovery and preliminary SAR of a novel series of DYRK1B and DYRK1A inhibitors von Anderson, Kevin, Chen, Yi, Chen, Zhi, Dominique, Romyr, Glenn, Kelli, He, Yang, Janson, Cheryl, Luk, Kin-Chun, Lukacs, Christine, Polonskaia, Ann, Qiao, Qi, Railkar, Aruna, Rossman, Pamela, Sun, Hongmao, Xiang, Qing, Vilenchik, Masha, Wovkulich, Peter, Zhang, Xiaolei

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Effects of LTB4 receptor antagonism on pulmonary inflammation in rodents and non-human primates von Hicks, Alexandra, Goodnow, Robert, Cavallo, Gary, Tannu, Shahid A., Ventre, Jessica D., Lavelle, Danielle, Lora, Jose M., Satjawatcharaphong, John, Brovarney, Martin, Dabbagh, Karim, Tare, Nadine S., Oh, Hyesun, Lamb, Martin, Sidduri, Achyutharao, Dominique, Romyr, Qiao, Qi, Lou, Jian Ping, Gillespie, Paul, Fotouhi, Nader, Kowalczyk, Agnieszka, Kurylko, Grazyna, Hamid, Rachid, Wright, Matthew B., Pamidimukkala, Anjula, Egan, Thomas, Gubler, Ueli, Hoffman, Ann F., Wei, Xin, Li, Ying L., O’Neil, John, Marcano, Ruben, Pozzani, Karen, Molinaro, Tina, Santiago, Jennifer, Singer, Laura, Hargaden, Maureen, Moore, David, Catala, A. Robert, Chao, Lisa C.F., Benson, Janet, March, Thomas, Venkat, Radhika, Mancebo, Helena, Renzetti, Louis M.

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Abstract LB006: PC14586: The first orally bioavailable small molecule reactivator of Y220C mutant p53 in clinical development von Dumble, Melissa, Xu, Lizhong, Dominique, Romyr, Liu, Binbin, Yang, Hong, McBrayer, Mary-Kate, Thomas, Dafydd, Fahr, Bruce, Li, Hongju, Huang, Kuo-Sen, Robell, Kimberly, Mulligan, Chris, Russo, Brandon, Puzio-Kuter, Anna, Davis, Thomas, Vu, Binh

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Discovery of Rezatapopt (PC14586), a First-in-Class, Small-Molecule Reactivator of p53 Y220C Mutant in Development von Vu, Binh T., Dominique, Romyr, Fahr, Bruce J., Li, Hongju H., Fry, David C., Xu, Lizhong, Yang, Hong, Puzio-Kuter, Anna, Good, Andrew, Liu, Binbin, Huang, Kuo-Sen, Tanaka, Naoko, Davis, Thomas W., Dumble, Melissa L.

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Transition metal catalyzed neoglycoconjugate syntheses von Roy, R., Das, S. K., Dominique, Romyr, Trono, M. C., Hernández-Mateo, Fernando, Santoyo-González, F.

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A facile new procedure for the deprotection of allyl ethers under mild conditions von Hu, Yun-Jin, Dominique, Romyr, Das, Sanjoy Kumar, Roy, René

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Process Research on a Phenoxybutyric Acid LTB4 Receptor Antagonist. Efficient Kilogram-Scale Synthesis of a 3,5-Bisarylphenol Core von Shu, Lianhe, Wang, Ping, Radinov, Roumen, Dominique, Romyr, Wright, James, Alabanza, Lady Mae, Dong, Yan

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Discovery of Novel and Potent Leukotriene B 4 Receptor Antagonists. Part 1 von Goodnow, Robert A., Hicks, Alexandra, Sidduri, Achyutharao, Kowalczyk, Agnieszka, Dominique, Romyr, Qiao, Qi, Lou, Jian Ping, Gillespie, Paul, Fotouhi, Nader, Tilley, Jefferson, Cohen, Noal, Choudhry, Satish, Cavallo, Gary, Tannu, Shahid A., Ventre, Jessica D., Lavelle, Danielle, Tare, Nadine S., Oh, Hyesun, Lamb, Martin, Kurylko, Grazyna, Hamid, Rachid, Wright, Matthew B., Pamidimukkala, Anjula, Egan, Thomas, Gubler, Ueli, Hoffman, Ann F., Wei, Xin, Li, Ying L., O’Neil, John, Marcano, Ruben, Pozzani, Karen, Molinaro, Tina, Santiago, Jennifer, Singer, Laura, Hargaden, Maureen, Moore, David, Catala, A. Robert, Chao, Lisa C. F., Hermann, Gesine, Venkat, Radhika, Mancebo, Helena, Renzetti, Louis M.

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Extended Alkenyl Glycosides by Ruthenium-Catalyzed Cross-Metathesis Reaction and Application toward Novel C-Linked Pseudodisaccharides von Roy, René, Dominique, Romyr, Das, Sanjoy K

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Discovery of Novel and Potent Leukotriene B4 Receptor Antagonists. Part 1 von Goodnow, Robert A, Hicks, Alexandra, Sidduri, Achyutharao, Kowalczyk, Agnieszka, Dominique, Romyr, Qiao, Qi, Lou, Jian Ping, Gillespie, Paul, Fotouhi, Nader, Tilley, Jefferson, Cohen, Noal, Choudhry, Satish, Cavallo, Gary, Tannu, Shahid A, Ventre, Jessica D, Lavelle, Danielle, Tare, Nadine S, Oh, Hyesun, Lamb, Martin, Kurylko, Grazyna, Hamid, Rachid, Wright, Matthew B, Pamidimukkala, Anjula, Egan, Thomas, Gubler, Ueli, Hoffman, Ann F, Wei, Xin, Li, Ying L, O’Neil, John, Marcano, Ruben, Pozzani, Karen, Molinaro, Tina, Santiago, Jennifer, Singer, Laura, Hargaden, Maureen, Moore, David, Catala, A. Robert, Chao, Lisa C. F, Hermann, Gesine, Venkat, Radhika, Mancebo, Helena, Renzetti, Louis M

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Alkenyl O- and C-glycopyranoside homodimerization by olefin metathesis reaction von Dominique, Romyr, Das, Sanjoy K., Roy, René

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Methods and compounds for restoring mutant p53 function von Li, Hongju, Vu, Binh, Dominique, Romyr

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Heterocycles as WIP1 Inhibitors von Li, Hongju, Vu, Binh, Chen, Yi, Dominique, Romyr

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Methods and compounds for restoring mutant p53 function von Fahr, Bruce, Li, Hongju, Vu, Binh, Chen, Yi, Dominique, Romyr

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METHODS AND COMPOUNDS FOR RESTORING MUTANT p53 FUNCTION von Li, Hongju, Vu, Binh, Dominique, Romyr

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Stereoselective synthesis of glycoclusters using an olefin metathesis and Sharpless dihydroxylation sequence von Dominique, Romyr, Roy, René

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METHODS AND COMPOUNDS FOR RESTORING MUTANT p53 FUNCTION von Fahr, Bruce, Good, Andrew, Li, Hongju, Vu, Binh, Dominique, Romyr

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Methods and compounds for restoring mutant p53 function von Li, Hongju, Vu, Binh, Dominique, Romyr

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Methods and compounds for restoring mutant p53 function von Fahr, Bruce, Good, Andrew, Li, Hongju, Vu, Binh, Dominique, Romyr

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Methods and compounds for restoring mutant p53 function von Fahr, Bruce, Good, Andrew, Li, Hongju, Vu, Binh, Dominique, Romyr

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