Impact of spliceosome mutations on RNA splicing in myelodysplasia: dysregulated genes/pathways and clinical associations von Pellagatti, Andrea, Armstrong, Richard N., Steeples, Violetta, Sharma, Eshita, Repapi, Emmanouela, Singh, Shalini, Sanchi, Andrea, Radujkovic, Aleksandar, Horn, Patrick, Dolatshad, Hamid, Roy, Swagata, Broxholme, John, Lockstone, Helen, Taylor, Stephen, Giagounidis, Aristoteles, Vyas, Paresh, Schuh, Anna, Hamblin, Angela, Papaemmanuil, Elli, Killick, Sally, Malcovati, Luca, Hennrich, Marco L., Gavin, Anne-Claude, Ho, Anthony D., Luft, Thomas, Hellström-Lindberg, Eva, Cazzola, Mario, Smith, Christopher W.J., Smith, Stephen, Boultwood, Jacqueline

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SF3B1 mutations induce R-loop accumulation and DNA damage in MDS and leukemia cells with therapeutic implications von Singh, Shalini, Ahmed, Doaa, Dolatshad, Hamid, Tatwavedi, Dharamveer, Schulze, Ulrike, Sanchi, Andrea, Ryley, Sarah, Dhir, Ashish, Carpenter, Lee, Watt, Suzanne M., Roberts, David J., Abdel-Aal, Amal M., Sayed, Sohair K., Mohamed, Somaia A., Schuh, Anna, Vyas, Paresh, Killick, Sally, Kotini, Andriana G., Papapetrou, Eirini P., Wiseman, Daniel H., Pellagatti, Andrea, Boultwood, Jacqueline

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Application of CRISPR/Cas9 genome editing to the study and treatment of disease von Pellagatti, Andrea, Dolatshad, Hamid, Valletta, Simona, Boultwood, Jacqueline

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ASXL1 mutations are associated with distinct epigenomic alterations that lead to sensitivity to venetoclax and azacytidine von Rahmani, Nora E., Ramachandra, Nandini, Sahu, Srabani, Gitego, Nadege, Lopez, Andrea, Pradhan, Kith, Bhagat, Tushar D., Gordon-Mitchell, Shanisha, Pena, Bianca Rivera, Kazemi, Mohammad, Rao, Keshav, Giricz, Orsi, Maqbool, Shahina Bano, Olea, Raul, Zhao, Yongmei, Zhang, Jinghang, Dolatshad, Hamid, Tittrea, Vickram, Tatwavedi, Dharamveer, Singh, Shalini, Lee, Juseong, Sun, Tianyu, Steidl, Ulrich, Shastri, Aditi, Inoue, Daichi, Abdel-Wahab, Omar, Pellagatti, Andrea, Gavathiotis, Evripidis, Boultwood, Jacqueline, Verma, Amit

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Embryonic Development of Circadian Oscillations in the Mouse Hypothalamus von Wreschnig, Daniel, Dolatshad, Hamid, Davis, Fred C.

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ASXL1 mutation correction by CRISPR/Cas9 restores gene function in leukemia cells and increases survival in mouse xenografts von Valletta, Simona, Dolatshad, Hamid, Bartenstein, Matthias, Yip, Bon Ham, Bello, Erica, Gordon, Shanisha, Yu, Yiting, Shaw, Jacqueline, Roy, Swagata, Scifo, Laura, Schuh, Anna, Pellagatti, Andrea, Fulga, Tudor A, Verma, Amit, Boultwood, Jacqueline

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Clustered Regularly Interspaced Short Palindromic Repeats/Cas9 Gene Editing Technique in Xenotransplantation von Naeimi Kararoudi, Meisam, Hejazi, Seyyed S, Elmas, Ezgi, Hellström, Mats, Naeimi Kararoudi, Maryam, Padma, Arvind M, Lee, Dean, Dolatshad, Hamid

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Differential expression of the circadian clock in maternal and embryonic tissues of mice von Dolatshad, Hamid, Cary, Andrew J, Davis, Fred C

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A fear-inducing odor alters PER2 and c-Fos expression in brain regions involved in fear memory von Pantazopoulos, Harry, Dolatshad, Hamid, Davis, Fred C

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Application of induced pluripotent stem cell technology for the investigation of hematological disorders von Dolatshad, Hamid, Tatwavedi, Dharamveer, Ahmed, Doaa, Tegethoff, Jana F., Boultwood, Jacqueline, Pellagatti, Andrea

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Effects of prolactin on movement disorders and APOE, GFAP, and PRL receptor gene expression following intracerebral hemorrhage in rats von Yousefvand, Shiba, Hadjzadeh, Mousa-Al-Reza, Keshavarzi, Zakieh, Dolatshad, Hamid, Vafaee, Farzaneh, Mahmoudabady, Maryam, Gholamzadeh Virany, Zahra

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The role of splicing factor mutations in the pathogenesis of the myelodysplastic syndromes von Boultwood, Jacqueline, Dolatshad, Hamid, Varanasi, Satya S., Yip, Bon Ham, Pellagatti, Andrea

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The U2AF1S34F mutation induces lineage-specific splicing alterations in myelodysplastic syndromes von Yip, Bon Ham, Steeples, Violetta, Repapi, Emmanouela, Armstrong, Richard N, Llorian, Miriam, Roy, Swagata, Shaw, Jacqueline, Dolatshad, Hamid, Taylor, Stephen, Verma, Amit, Bartenstein, Matthias, Vyas, Paresh, Cross, Nicholas Cp, Malcovati, Luca, Cazzola, Mario, Hellström-Lindberg, Eva, Ogawa, Seishi, Smith, Christopher Wj, Pellagatti, Andrea, Boultwood, Jacqueline

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The Neuroprotective Effects of Heat Shock Protein 27 Overexpression in Transgenic Animals against Kainate-induced Seizures and Hippocampal Cell Death von Akbar, Mohammed T., Lundberg, Anna M.C., Liu, Ke, Vidyadaran, Sharmili, Wells, Kim E., Dolatshad, Hamid, Wynn, Sarah, Wells, Dominic J., Latchman, David S., de Belleroche, Jacqueline

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Combining gene mutation with gene expression data improves outcome prediction in myelodysplastic syndromes von Gerstung, Moritz, Pellagatti, Andrea, Malcovati, Luca, Giagounidis, Aristoteles, Porta, Matteo G Della, Jädersten, Martin, Dolatshad, Hamid, Verma, Amit, Cross, Nicholas C. P., Vyas, Paresh, Killick, Sally, Hellström-Lindberg, Eva, Cazzola, Mario, Papaemmanuil, Elli, Campbell, Peter J., Boultwood, Jacqueline

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The protective effects of prolactin on brain injury von Yousefvand, Shiba, Hadjzadeh, Mousa-Al-Reza, Vafaee, Farzaneh, Dolatshad, Hamid

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ASXL1 Mutations Are Associated with Widespread and Distinct DNA Methylation Alterations von Rahmani, Nora E, Ramachandra, Nandini, Bhagat, Tushar D, Gordon, Shanisha, Pradhan, Kith, Rivera Pena, Bianca, Kazemi, Mohammad, Giricz, Orsi, Maqbool, Shahina, Olea, Raul, Dolatshad, Hamid, Tittrea, Vickram, Tatwavedi, Dharamveer, Singh, Shalini, Pellagatti, Andrea, Boultwood, Jacqueline, Verma, Amit

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Generation of Knock-out Primary and Expanded Human NK Cells Using Cas9 Ribonucleoproteins von Naeimi Kararoudi, Meisam, Dolatshad, Hamid, Trikha, Prashant, Hussain, Syed-Rehan A, Elmas, Ezgi, Foltz, Jennifer A, Moseman, Jena E, Thakkar, Aarohi, Nakkula, Robin J, Lamb, Margaret, Chakravarti, Nitin, McLaughlin, K John, Lee, Dean A

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Lineage-Specific Aberrant mRNA Splicing By U2AF1 Mutation Alters Erythroid and Granulomonocytic Differentiation von Yip, Bon Ham, Roy, Swagata, Dolatshad, Hamid, Shaw, Jacqueline, Ogawa, Seishi, Pellagatti, Andrea, Boultwood, Jacqueline

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versatile transgenic allele for mouse overexpression studies von Dolatshad, Hamid, Biggs, Daniel, Diaz, Rebeca, Hortin, Nicole, Preece, Christopher, Davies, Benjamin

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