Multiple myeloma cells alter the senescence phenotype of bone marrow mesenchymal stromal cells under participation of the DLK1-DIO3 genomic region von Berenstein, Rimma, Blau, Olga, Nogai, Axel, Waechter, Marlies, Slonova, Ekaterina, Schmidt-Hieber, Martin, Kunitz, Annegret, Pezzutto, Antonio, Doerken, Bernd, Blau, Igor Wolfgang

Volltext

Parenteral nutrition support for patients with pancreatic cancer. Results of a phase II study von Pelzer, Uwe, Arnold, Dirk, Gövercin, Mehmet, Stieler, Jens, Doerken, Bernd, Riess, Hanno, Oettle, Helmut

Volltext

Pathogenesis of Non-Hodgkin's Lymphoma von Nogai, Hendrik, Dörken, Bernd, Lenz, Georg

Volltext

Senescence-associated reprogramming promotes cancer stemness von Milanovic, Maja, Fan, Dorothy N. Y., Belenki, Dimitri, Däbritz, J. Henry M., Zhao, Zhen, Yu, Yong, Dörr, Jan R., Dimitrova, Lora, Lenze, Dido, Monteiro Barbosa, Ines A., Mendoza-Parra, Marco A., Kanashova, Tamara, Metzner, Marlen, Pardon, Katharina, Reimann, Maurice, Trumpp, Andreas, Dörken, Bernd, Zuber, Johannes, Gronemeyer, Hinrich, Hummel, Michael, Dittmar, Gunnar, Lee, Soyoung, Schmitt, Clemens A.

Volltext

CONKO-005: Adjuvant Chemotherapy With Gemcitabine Plus Erlotinib Versus Gemcitabine Alone in Patients After R0 Resection of Pancreatic Cancer: A Multicenter Randomized Phase III Tr... von Sinn, Marianne, Bahra, Marcus, Liersch, Torsten, Gellert, Klaus, Messmann, Helmut, Bechstein, Wolf, Waldschmidt, Dirk, Jacobasch, Lutz, Wilhelm, Martin, Rau, Bettina M, Grützmann, Robert, Weinmann, Arndt, Maschmeyer, Georg, Pelzer, Uwe, Stieler, Jens M, Striefler, Jana K, Ghadimi, Michael, Bischoff, Sven, Dörken, Bernd, Oettle, Helmut, Riess, Hanno

Volltext

Best supportive care (BSC) versus oxaliplatin, folinic acid and 5-fluorouracil (OFF) plus BSC in patients for second-line advanced pancreatic cancer: A phase III-study from the Ger... von Pelzer, Uwe, Schwaner, Ingo, Stieler, Jens, Adler, Mathias, Seraphin, Jörg, Dörken, Bernd, Riess, Hanno, Oettle, Helmut

Volltext

BCR-ABL-positive acute myeloid leukemia: a new entity? Analysis of clinical and molecular features von Neuendorff, Nina Rosa, Burmeister, Thomas, Dörken, Bernd, Westermann, Jörg

Volltext

Efficacy of Prophylactic Low-Molecular Weight Heparin for Ambulatory Patients With Advanced Pancreatic Cancer: Outcomes From the CONKO-004 Trial von Pelzer, Uwe, Opitz, Bernhard, Deutschinoff, Gerd, Stauch, Martina, Reitzig, Peter C, Hahnfeld, Sabine, Müller, Lothar, Grunewald, Martina, Stieler, Jens M, Sinn, Marianne, Denecke, Timm, Bischoff, Sven, Oettle, Helmut, Dörken, Bernd, Riess, Hanno

Volltext

Second-Line Oxaliplatin, Folinic Acid, and Fluorouracil Versus Folinic Acid and Fluorouracil Alone for Gemcitabine-Refractory Pancreatic Cancer: Outcomes From the CONKO-003 Trial von OETTLE, Helmut, RIESS, Hanno, BISCHOFF, Sven, SINN, Marianne, DÖRKEN, Bernd, PELZER, Uwe, STIELER, Jens M, HEIL, Gerhard, SCHWANER, Ingo, SERAPHIN, Jörg, GÖRNER, Martin, MÖLLE, Matthias, GRETEN, Tim F, LAKNER, Volker

Volltext

Hematopoietic lineage distribution and evolutionary dynamics of clonal hematopoiesis von Arends, Christopher Maximilian, Galan-Sousa, Joel, Hoyer, Kaja, Chan, Willy, Jäger, Marten, Yoshida, Kenichi, Seemann, Ricarda, Noerenberg, Daniel, Waldhueter, Nils, Fleischer-Notter, Helga, Christen, Friederike, Schmitt, Clemens A., Dörken, Bernd, Pelzer, Uwe, Sinn, Marianne, Zemojtel, Tomasz, Ogawa, Seishi, Märdian, Sven, Schreiber, Adrian, Kunitz, Annegret, Krüger, Ulrike, Bullinger, Lars, Mylonas, Elena, Frick, Mareike, Damm, Frederik

Volltext

Synthetic lethal metabolic targeting of cellular senescence in cancer therapy von Dörr, Jan R., Yu, Yong, Milanovic, Maja, Beuster, Gregor, Zasada, Christin, Däbritz, J. Henry M., Lisec, Jan, Lenze, Dido, Gerhardt, Anne, Schleicher, Katharina, Kratzat, Susanne, Purfürst, Bettina, Walenta, Stefan, Mueller-Klieser, Wolfgang, Gräler, Markus, Hummel, Michael, Keller, Ulrich, Buck, Andreas K., Dörken, Bernd, Willmitzer, Lothar, Reimann, Maurice, Kempa, Stefan, Lee, Soyoung, Schmitt, Clemens A.

Volltext

PTEN loss defines a PI3K/AKT pathway-dependent germinal center subtype of diffuse large B-cell lymphoma von Pfeifer, Matthias, Grau, Michael, Lenze, Dido, Wenzel, Sören-Sebastian, Wolf, Annette, Wollert-Wulf, Brigitte, Dietze, Kerstin, Nogai, Hendrik, Storek, Benjamin, Madle, Hannelore, Dörken, Bernd, Janz, Martin, Dirnhofer, Stephan, Lenz, Peter, Hummel, Michael, Tzankov, Alexandar, Lenz, Georg

Volltext

Pharmacological and genomic profiling identifies NF-κB–targeted treatment strategies for mantle cell lymphoma von Rahal, Rami, Frick, Mareike, Romero, Rodrigo, Korn, Joshua M, Kridel, Robert, Chun Chan, Fong, Meissner, Barbara, Bhang, Hyo-eun, Ruddy, Dave, Kauffmann, Audrey, Farsidjani, Ali, Derti, Adnan, Rakiec, Daniel, Naylor, Tara, Pfister, Estelle, Kovats, Steve, Kim, Sunkyu, Dietze, Kerstin, Dörken, Bernd, Steidl, Christian, Tzankov, Alexandar, Hummel, Michael, Monahan, John, Morrissey, Michael P, Fritsch, Christine, Sellers, William R, Cooke, Vesselina G, Gascoyne, Randy D, Lenz, Georg, Stegmeier, Frank

Volltext

Reduced Treatment Intensity in Patients with Early-Stage Hodgkin's Lymphoma von Engert, Andreas, Plütschow, Annette, Eich, Hans Theodor, Lohri, Andreas, Dörken, Bernd, Borchmann, Peter, Berger, Bernhard, Greil, Richard, Willborn, Kay C, Wilhelm, Martin, Debus, Jürgen, Eble, Michael J, Sökler, Martin, Ho, Antony, Rank, Andreas, Ganser, Arnold, Trümper, Lorenz, Bokemeyer, Carsten, Kirchner, Hartmut, Schubert, Jörg, Král, Zdenek, Fuchs, Michael, Müller-Hermelink, Hans-Konrad, Müller, Rolf-Peter, Diehl, Volker

Volltext

Reduced intensity conditioning prior to allogeneic stem cell transplantation in first complete remission is effective in patients with acute myeloid leukemia and an intermediate-ri... von Hemmati, Philipp G., Terwey, Theis H., Massenkeil, Gero, le Coutre, Philipp, Vuong, Lam G., Neuburger, Stefan, Dörken, Bernd, Arnold, Renate

Volltext

Reduced-intensity chemotherapy and PET-guided radiotherapy in patients with advanced stage Hodgkin's lymphoma (HD15 trial): a randomised, open-label, phase 3 non-inferiority trial von Engert, Andreas, MD, Haverkamp, Heinz, PhD, Kobe, Carsten, MD, Markova, Jana, MD, Renner, Christoph, MD, Ho, Antony, MD, Zijlstra, Josée, MD, Král, Zdenek, MD, Fuchs, Michael, MD, Hallek, Michael, MD, Kanz, Lothar, MD, Döhner, Hartmut, MD, Dörken, Bernd, MD, Engel, Nicole, MD, Topp, Max, MD, Klutmann, Susanne, MD, Amthauer, Holger, MD, Bockisch, Andreas, MD, Kluge, Regine, MD, Kratochwil, Clemens, MD, Schober, Otmar, MD, Greil, Richard, MD, Andreesen, Reinhard, MD, Kneba, Michael, MD, Pfreundschuh, Michael, MD, Stein, Harald, MD, Eich, Hans Theodor, MD, Müller, Rolf-Peter, MD, Dietlein, Markus, MD, Borchmann, Peter, MD, Diehl, Volker, MD

Volltext

Adjuvant Chemotherapy With Gemcitabine vs Observation in Patients Undergoing Curative-Intent Resection of Pancreatic Cancer: A Randomized Controlled Trial von Oettle, Helmut, Post, Stefan, Neuhaus, Peter, Gellert, Klaus, Langrehr, Jan, Ridwelski, Karsten, Schramm, Harald, Fahlke, Joerg, Zuelke, Carl, Burkart, Christof, Gutberlet, Klaus, Kettner, Erika, Schmalenberg, Harald, Weigang-Koehler, Karin, Bechstein, Wolf-Otto, Niedergethmann, Marco, Schmidt-Wolf, Ingo, Roll, Lars, Doerken, Bernd, Riess, Hanno

Volltext

Targeting the Senescence-Overriding Cooperative Activity of Structurally Unrelated H3K9 Demethylases in Melanoma von Yu, Yong, Schleich, Kolja, Yue, Bin, Ji, Sujuan, Lohneis, Philipp, Kemper, Kristel, Silvis, Mark R., Qutob, Nouar, van Rooijen, Ellen, Werner-Klein, Melanie, Li, Lianjie, Dhawan, Dhriti, Meierjohann, Svenja, Reimann, Maurice, Elkahloun, Abdel, Treitschke, Steffi, Dörken, Bernd, Speck, Christian, Mallette, Frédérick A., Zon, Leonard I., Holmen, Sheri L., Peeper, Daniel S., Samuels, Yardena, Schmitt, Clemens A., Lee, Soyoung

Volltext

The AP-1-BATF and -BATF3 module is essential for growth, survival and TH17/ILC3 skewing of anaplastic large cell lymphoma von Schleussner, Nikolai, Merkel, Olaf, Costanza, Mariantonia, Liang, Huan-Chang, Hummel, Franziska, Romagnani, Chiara, Durek, Pawel, Anagnostopoulos, Ioannis, Hummel, Michael, Jöhrens, Korinna, Niedobitek, Antonia, Griffin, Patrick R., Piva, Roberto, Sczakiel, Henrike L., Woessmann, Wilhelm, Damm-Welk, Christine, Hinze, Christian, Stoiber, Dagmar, Gillissen, Bernd, Turner, Suzanne D., Kaergel, Eva, von Hoff, Linda, Grau, Michael, Lenz, Georg, Dörken, Bernd, Scheidereit, Claus, Kenner, Lukas, Janz, Martin, Mathas, Stephan

Volltext

Malt1-dependent RelB cleavage promotes canonical NF-κB activation in lymphocytes and lymphoma cell lines von Hailfinger, Stephan, Nogai, Hendrik, Pelzer, Christiane, Jaworski, Maike, Cabalzar, Katrin, Charton, Jean-Enno, Guzzardi, Montserrat, Décaillet, Chantal, Grau, Michael, Dörken, Bernd, Lenz, Peter, Lenz, Georg, Thome, Margot

Volltext