A direct role for SNX9 in the biogenesis of filopodia von Jarsch, Iris K, Gadsby, Jonathan R, Nuccitelli, Annalisa, Mason, Julia, Shimo, Hanae, Pilloux, Ludovic, Marzook, Bishara, Mulvey, Claire M, Dobramysl, Ulrich, Bradshaw, Charles R, Lilley, Kathryn S, Hayward, Richard D, Vaughan, Tristan J, Dobson, Claire L, Gallop, Jennifer L

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Preclinical development of a high affinity α-synuclein antibody, MEDI1341, that can enter the brain, sequester extracellular α-synuclein and attenuate α-synuclein spreading in vivo... von Schofield, Darren J., Irving, Lorraine, Calo, Laura, Bogstedt, Anna, Rees, Gareth, Nuccitelli, Annalisa, Narwal, Rajesh, Petrone, Marcella, Roberts, Jennifer, Brown, Lee, Cusdin, Fiona, Dosanjh, Bhupinder, Lloyd, Christopher, Dobson, Claire, Gurrell, Ian, Fraser, Graham, McFarlane, Mary, Rockenstein, Edward, Spencer, Brian, Masliah, Eliezer, Spillantini, Maria Grazia, Tan, Keith, Billinton, Andrew, Vaughan, Tris, Chessell, Iain, Perkinton, Michael S.

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Antibodies binding the head domain of P2X4 inhibit channel function and reverse neuropathic pain von Williams, Wendy A., Linley, John E., Jones, Clare A., Shibata, Yoko, Snijder, Arjan, Button, James, Hatcher, Jon P., Huang, Ling, Taddese, Bruck, Thornton, Peter, Schofield, Darren J., Thom, George, Popovic, Bojana, Dosanjh, Bhupinder, Wilkinson, Trevor, Hughes, Jane, Dobson, Claire L., Groves, Maria A., Webster, Carl I., Billinton, Andy, Vaughan, Tristan J., Chessell, Iain

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Stochastic assembly of biomacromolecular complexes: impact and implications on charge interpretation in native mass spectrometry von Yin, Victor, Devine, Paul W. A, Saunders, Janet C, Barendregt, Arjan, Cusdin, Fiona, Ristani, Alexandra, Hines, Alistair, Shepherd, Sam, Dembek, Marcin, Dobson, Claire L, Snijder, Joost, Bond, Nicholas J, Heck, Albert J. R

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Engineering the surface properties of a human monoclonal antibody prevents self-association and rapid clearance in vivo von Dobson, Claire L., Devine, Paul W. A., Phillips, Jonathan J., Higazi, Daniel R., Lloyd, Christopher, Popovic, Bojana, Arnold, Joanne, Buchanan, Andrew, Lewis, Arthur, Goodman, Joanne, van der Walle, Christopher F., Thornton, Peter, Vinall, Lisa, Lowne, David, Aagaard, Anna, Olsson, Lise-Lotte, Ridderstad Wollberg, Anna, Welsh, Fraser, Karamanos, Theodoros K., Pashley, Clare L., Iadanza, Matthew G., Ranson, Neil A., Ashcroft, Alison E., Kippen, Alistair D., Vaughan, Tristan J., Radford, Sheena E., Lowe, David C.

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Chemically Defined, High-Density Insect Cell-Based Expression System for Scalable AAV Vector Production von Kurasawa, James H., Park, Andrew, Sowers, Carrie R., Halpin, Rebecca A., Tovchigrechko, Andrey, Dobson, Claire L., Schmelzer, Albert E., Gao, Changshou, Wilson, Susan D., Ikeda, Yasuhiro

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Isolation of high-affinity, neutralizing anti-idiotype antibodies by phage and ribosome display for application in immunogenicity and pharmacokinetic analyses von Chin, Stacey E., Ferraro, Franco, Groves, Maria, Liang, Meina, Vaughan, Tristan J., Dobson, Claire L.

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Activity of murine surrogate antibodies for durvalumab and tremelimumab lacking effector function and the ability to deplete regulatory T cells in mouse models of cancer von Schofield, Darren J, Percival-Alwyn, Jennifer, Rytelewski, Mateusz, Hood, John, Rothstein, Raymond, Wetzel, Leslie, McGlinchey, Kelly, Adjei, Grace, Watkins, Amanda, Machiesky, LeeAnn, Chen, Weimin, Andrews, John, Groves, Maria, Morrow, Michelle, Stewart, Ross A, Leinster, Andrew, Wilkinson, Robert W, Hammond, Scott A, Luheshi, Nadia, Dobson, Claire, Oberst, Michael

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A novel IgE-neutralizing antibody for the treatment of severe uncontrolled asthma von Cohen, E Suzanne, Dobson, Claire L, Käck, Helena, Wang, Bing, Sims, Dorothy A, Lloyd, Christopher O, England, Elizabeth, Rees, D Gareth, Guo, Hongwei, Karagiannis, Sophia N, O'Brien, Siobhan, Persdotter, Sofia, Ekdahl, Helena, Butler, Robin, Keyes, Feenagh, Oakley, Sarah, Carlsson, Mats, Briend, Emmanuel, Wilkinson, Trevor, Anderson, Ian K, Monk, Phillip D, von Wachenfeldt, Karin, Eriksson, Per-Olof F, Gould, Hannah J, Vaughan, Tristan J, May, Richard D

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The T Cell Leukemia LIM Protein Lmo2 is Necessary for Adult Mouse Hematopoiesis von Yamada, Yoshihiro, Warren, Alan J., Dobson, Claire, Forster, Alan, Pannell, Richard, Rabbitts, Terence H.

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Human monomeric antibody fragments to TRAIL-R1 and TRAIL-R2 that display potent in vitro agonism von Dobson, Claire L., Main, Sarah, Newton, Philip, Chodorge, Matthieu, Cadwallader, Karen, Humphreys, Robin C., Albert, Vivian, Vaughan, Tristan J., Minter, Ralph R., Edwards, Bryan M.

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Juvenile Violent Victimization and Adult Criminal Outcomes: The Role of Military Service as a Turning Point in Young Adulthood von Orak, Ugur, Soileau, Christine, Harter, Jessica, Dobson, Claire, Huey Dye, Meredith

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The open to closed D-loop conformational switch determines length in filopodia-like actin bundles von Gadsby, Jonathan R, Ioannou, Pantelis Savvas, Butler, Richard, Mason, Julia, Smith, Alison J, Dobramysl, Ulrich, Chin, Stacey E, Dobson, Claire, Gallop, Jennifer L

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Characterization and preclinical evaluation of a protease activated receptor 2 (PAR2) monoclonal antibody as a preventive therapy for migraine von Kopruszinski, Caroline M, Thornton, Peter, Arnold, Joanne, Newton, Philip, Lowne, David, Navratilova, Edita, Swiokla, Juliana, Dodick, David W, Dobson, Claire, Gurrell, Ian, Chessell, Iain Patrick, Porreca, Frank

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Autoantibodies are associated with disease progression in idiopathic pulmonary fibrosis von Koether, Katerina, Besnard, Valérie, Sandig, Hilary, Carruthers, Alan, Miranda, Elena, Grootenboer-Mignot, Sabine, Taillé, Camille, Chevret, Sylvie, Valeyre, Dominique, Nunes, Hilario, Israel-Biet, Dominique, Lim, Wei Keat, Cottin, Vincent, Corkill, Dominic, Dobson, Claire, Groves, Maria, Ferraro, Franco, Guenzi, Edouard, Huang, Ling, Sulikowski, Michal, Mailleux, Arnaud, Murray, Lynne Anne, Mustelin, Thomas, Strickland, Ian, Sleeman, Matthew A, Crestani, Bruno

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Abstract 1828: AZD8853: A novel antibody targeting GDF15 for immunotherapy refractory tumors von Hurt, Elaine, Thomas, Suneetha, Mulgrew, Kathy, Blackmore, Stephen, Moynihan, James, Cusdin, Fiona, Dodd, Roger, Cariuk, Peter, Sigurdardottir, Anna, Brannigan, Emily, Dobson, Claire, Kumar, Rakesh, Cobbold, Mark

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Stochastic assembly of biomacromolecular complexes: impact and implications on charge interpretation in native mass spectrometry von Yin, Victor, Devine, Paul W A, Saunders, Janet C, Barendregt, Arjan, Cusdin, Fiona, Ristani, Alexandra, Hines, Alistair, Shepherd, Sam, Dembek, Marcin, Dobson, Claire L, Snijder, Joost, Bond, Nicholas J, Heck, Albert J R

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Assessment of AAV9 distribution and transduction in rats after administration through Intrastriatal, Intracisterna magna and Lumbar Intrathecal routes von Chandran, Jayanth, Chowdhury, Ekram Ahmed, Perkinton, Michael, Jamier, Tanguy, Sutton, Daniel, Wu, Shengjia, Dobson, Claire, Shah, Dhaval K., Chessell, Iain, Meno-Tetang, Guy M. L.

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Cranial osteology of the Middle Jurassic (Callovian) Martillichthys renwickae (Neopterygii, Pachycormiformes) with comments on the evolution and ecology of edentulous pachycormifor... von Dobson, Claire, Giles, Sam, Johanson, Zerina, Liston, Jeff, Friedman, Matt, Cavin, Lionel

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Structure and characterization of a high affinity C5a monoclonal antibody that blocks binding to C5aR1 and C5aR2 receptors von Colley, Caroline S, Popovic, Bojana, Sridharan, Sudharsan, Debreczeni, Judit E, Hargeaves, David, Fung, Michael, An, Ling-Ling, Edwards, Bryan, Arnold, Joanne, England, Elizabeth, Eghobamien, Laura, Sivars, Ulf, Flavell, Liz, Renshaw, Jonathan, Wickson, Kate, Warrener, Paul, Zha, Jingying, Bonnell, Jessica, Woods, Rob, Wilkinson, Trevor, Dobson, Claire, Vaughan, Tristan J

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