Sequence artifacts in DNA from formalin-fixed tissues: causes and strategies for minimization von Do, Hongdo, Dobrovic, Alexander

Volltext

Molecular and clinical determinants of response and resistance to rucaparib for recurrent ovarian cancer treatment in ARIEL2 (Parts 1 and 2) von Swisher, Elizabeth M., Kwan, Tanya T., Oza, Amit M., Tinker, Anna V., Ray-Coquard, Isabelle, Oaknin, Ana, Coleman, Robert L., Aghajanian, Carol, Konecny, Gottfried E., O’Malley, David M., Leary, Alexandra, Provencher, Diane, Welch, Stephen, Chen, Lee-may, Wahner Hendrickson, Andrea E., Ma, Ling, Ghatage, Prafull, Kristeleit, Rebecca S., Dorigo, Oliver, Musafer, Ashan, Kaufmann, Scott H., Elvin, Julia A., Lin, Douglas I., Chambers, Setsuko K., Dominy, Erin, Vo, Lan-Thanh, Goble, Sandra, Maloney, Lara, Giordano, Heidi, Harding, Thomas, Dobrovic, Alexander, Scott, Clare L., Lin, Kevin K., McNeish, Iain A.

Volltext

Combination Osimertinib and Gefitinib in C797S and T790M EGFR-Mutated Non–Small Cell Lung Cancer von Arulananda, Surein, Do, Hongdo, Musafer, Ashan, Mitchell, Paul, Dobrovic, Alexander, John, Thomas

Volltext

GRIDSS: sensitive and specific genomic rearrangement detection using positional de Bruijn graph assembly von Cameron, Daniel L, Schröder, Jan, Penington, Jocelyn Sietsma, Do, Hongdo, Molania, Ramyar, Dobrovic, Alexander, Speed, Terence P, Papenfuss, Anthony T

Volltext

A reference collection of patient-derived cell line and xenograft models of proneural, classical and mesenchymal glioblastoma von Stringer, Brett W., Day, Bryan W., D’Souza, Rochelle C. J., Jamieson, Paul R., Ensbey, Kathleen S., Bruce, Zara C., Lim, Yi Chieh, Goasdoué, Kate, Offenhäuser, Carolin, Akgül, Seçkin, Allan, Suzanne, Robertson, Thomas, Lucas, Peter, Tollesson, Gert, Campbell, Scott, Winter, Craig, Do, Hongdo, Dobrovic, Alexander, Inglis, Po-Ling, Jeffree, Rosalind L., Johns, Terrance G., Boyd, Andrew W.

Volltext

BRCA Mutation Frequency and Patterns of Treatment Response in BRCA Mutation–Positive Women With Ovarian Cancer: A Report From the Australian Ovarian Cancer Study Group von ALSOP, Kathryn, FEREDAY, Sian, FRIEDLANDER, Michael, FOX, Stephen, BOWTELL, David, MITCHELL, Gillian, MELDRUM, Cliff, DEFAZIO, Anna, EMMANUEL, Catherine, GEORGE, Joshy, DOBROVIC, Alexander, BIRRER, Michael J, WEBB, Penelope M, STEWART, Colin

Volltext

A critical review of the role of Fc gamma receptor polymorphisms in the response to monoclonal antibodies in cancer von Mellor, James D, Brown, Michael P, Irving, Helen R, Zalcberg, John R, Dobrovic, Alexander

Volltext

BCL-XL and MCL-1 are the key BCL-2 family proteins in melanoma cell survival von Lee, Erinna F., Harris, Tiffany J., Tran, Sharon, Evangelista, Marco, Arulananda, Surein, John, Thomas, Ramnac, Celeste, Hobbs, Chloe, Zhu, Haoran, Gunasingh, Gency, Segal, David, Behren, Andreas, Cebon, Jonathan, Dobrovic, Alexander, Mariadason, John M., Strasser, Andreas, Rohrbeck, Leona, Haass, Nikolas K., Herold, Marco J., Fairlie, W. Douglas

Volltext

Reducing sequence artifacts in amplicon-based massively parallel sequencing of formalin-fixed paraffin-embedded DNA by enzymatic depletion of uracil-containing templates von Do, Hongdo, Wong, Stephen Q, Li, Jason, Dobrovic, Alexander

Volltext

Acquired RAD51C Promoter Methylation Loss Causes PARP Inhibitor Resistance in High-Grade Serous Ovarian Carcinoma von Nesic, Ksenija, Kondrashova, Olga, Hurley, Rachel M, McGehee, Cordelia D, Vandenberg, Cassandra J, Ho, Gwo-Yaw, Lieschke, Elizabeth, Dall, Genevieve, Bound, Nirashaa, Shield-Artin, Kristy, Radke, Marc, Musafer, Ashan, Chai, Zi Qing, Ghamsari, Mohammad Reza Eftekhariyan, Harrell, Maria I, Kee, Damien, Olesen, Inger, McNally, Orla, Traficante, Nadia, Australian Ovarian Cancer Study, DeFazio, Anna, Bowtell, David D L, Swisher, Elizabeth M, Weroha, S John, Nones, Katia, Waddell, Nicola, Kaufmann, Scott H, Dobrovic, Alexander, Wakefield, Matthew J, Scott, Clare L

Volltext

The role of aberrant DNA methylation in cancer initiation and clinical impacts von Geissler, Franziska, Nesic, Ksenija, Kondrashova, Olga, Dobrovic, Alexander, Swisher, Elizabeth M., Scott, Clare L., J. Wakefield, Matthew

Volltext

High resolution melting analysis for rapid and sensitive EGFR and KRAS mutation detection in formalin fixed paraffin embedded biopsies von Do, Hongdo, Krypuy, Michael, Mitchell, Paul L, Fox, Stephen B, Dobrovic, Alexander

Volltext

High resolution melting analysis for the rapid and sensitive detection of mutations in clinical samples: KRAS codon 12 and 13 mutations in non-small cell lung cancer von Krypuy, Michael, Newnham, Genni M, Thomas, David M, Conron, Matthew, Dobrovic, Alexander

Volltext

Empirical array quality weights in the analysis of microarray data von Ritchie, Matthew E, Diyagama, Dileepa, Neilson, Jody, van Laar, Ryan, Dobrovic, Alexander, Holloway, Andrew, Smyth, Gordon K

Volltext

Mismatch Repair Protein Defects and Microsatellite Instability in Malignant Pleural Mesothelioma von Arulananda, Surein, Thapa, Bibhusal, Walkiewicz, Marzena, Zapparoli, Giada V., Williams, David S., Dobrovic, Alexander, John, Thomas

Volltext

Probe-Free Digital PCR Quantitative Methodology to Measure Donor-Specific Cell-Free DNA after Solid-Organ Transplantation von Goh, Su Kah, Muralidharan, Vijayaragavan, Christophi, Christopher, Do, Hongdo, Dobrovic, Alexander

Volltext

Homologous Recombination DNA Repair Pathway Disruption and Retinoblastoma Protein Loss Are Associated with Exceptional Survival in High-Grade Serous Ovarian Cancer von Garsed, Dale W, Alsop, Kathryn, Fereday, Sian, Emmanuel, Catherine, Kennedy, Catherine J, Etemadmoghadam, Dariush, Gao, Bo, Gebski, Val, Garès, Valérie, Christie, Elizabeth L, Wouters, Maartje C A, Milne, Katy, George, Joshy, Patch, Ann-Marie, Li, Jason, Arnau, Gisela Mir, Semple, Timothy, Gadipally, Sreeja R, Chiew, Yoke-Eng, Hendley, Joy, Mikeska, Thomas, Zapparoli, Giada V, Amarasinghe, Kaushalya, Grimmond, Sean M, Pearson, John V, Waddell, Nicola, Hung, Jillian, Stewart, Colin J R, Sharma, Raghwa, Allan, Prue E, Rambau, Peter F, McNally, Orla, Mileshkin, Linda, Hamilton, Anne, Ananda, Sumitra, Grossi, Marisa, Cohen, Paul A, Leung, Yee C, Rome, Robert M, Beale, Philip, Blomfield, Penny, Friedlander, Michael, Brand, Alison, Dobrovic, Alexander, Köbel, Martin, Harnett, Paul, Nelson, Brad H, Bowtell, David D L, deFazio, Anna

Volltext

Limited copy number-high resolution melting (LCN-HRM) enables the detection and identification by sequencing of low level mutations in cancer biopsies von Do, Hongdo, Dobrovic, Alexander

Volltext

Wnt inhibitory factor 1 is epigenetically silenced in human osteosarcoma, and targeted disruption accelerates osteosarcomagenesis in mice von Kansara, Maya, Tsang, Michael, Kodjabachian, Laurent, Sims, Natalie A, Trivett, Melanie K, Ehrich, Mathias, Dobrovic, Alexander, Slavin, John, Choong, Peter F M, Simmons, Paul J, Dawid, Igor B, Thomas, David M

Volltext

Reducing Artifactual EGFR T790M Mutations in DNA from Formalin-Fixed Paraffin-Embedded Tissue by Use of Thymine-DNA Glycosylase von Do, Hongdo, Molania, Ramyar, Mitchell, Paul L, Vaiskunaite, Rita, Murdoch, John D, Dobrovic, Alexander

Volltext