Brain Tumor Stem Cells: Bringing Order to the Chaos of Brain Cancer von Dirks, Peter B

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Functional Enhancers Shape Extrachromosomal Oncogene Amplifications von Morton, Andrew R., Dogan-Artun, Nergiz, Faber, Zachary J., MacLeod, Graham, Bartels, Cynthia F., Piazza, Megan S., Allan, Kevin C., Mack, Stephen C., Wang, Xiuxing, Gimple, Ryan C., Wu, Qiulian, Rubin, Brian P., Shetty, Shashirekha, Angers, Stephane, Dirks, Peter B., Sallari, Richard C., Lupien, Mathieu, Rich, Jeremy N., Scacheri, Peter C.

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GLUT1 inhibition blocks growth of RB1-positive triple negative breast cancer von Wu, Qin, ba-alawi, Wail, Deblois, Genevieve, Cruickshank, Jennifer, Duan, Shili, Lima-Fernandes, Evelyne, Haight, Jillian, Tonekaboni, Seyed Ali Madani, Fortier, Anne-Marie, Kuasne, Hellen, McKee, Trevor D., Mahmoud, Hassan, Kushida, Michelle, Cameron, Sarina, Dogan-Artun, Nergiz, Chen, WenJun, Nie, Yan, Zhang, Lan Xin, Vellanki, Ravi N., Zhou, Stanley, Prinos, Panagiotis, Wouters, Bradly G., Dirks, Peter B., Done, Susan J., Park, Morag, Cescon, David W., Haibe-Kains, Benjamin, Lupien, Mathieu, Arrowsmith, Cheryl H.

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Brain tumor stem cells: The cancer stem cell hypothesis writ large von Dirks, Peter B.

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Single cell-derived clonal analysis of human glioblastoma links functional and genomic heterogeneity von Meyer, Mona, Reimand, Jüri, Lan, Xiaoyang, Head, Renee, Zhu, Xueming, Kushida, Michelle, Bayani, Jane, Pressey, Jessica C., Lionel, Anath C., Clarke, Ian D., Cusimano, Michael, Squire, Jeremy A., Scherer, Stephen W., Bernstein, Mark, Woodin, Melanie A., Bader, Gary D., Dirks, Peter B.

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Fate mapping of human glioblastoma reveals an invariant stem cell hierarchy von Lan, Xiaoyang, Jörg, David J., Cavalli, Florence M. G., Richards, Laura M., Nguyen, Long V., Vanner, Robert J., Guilhamon, Paul, Lee, Lilian, Kushida, Michelle M., Pellacani, Davide, Park, Nicole I., Coutinho, Fiona J., Whetstone, Heather, Selvadurai, Hayden J., Che, Clare, Luu, Betty, Carles, Annaick, Moksa, Michelle, Rastegar, Naghmeh, Head, Renee, Dolma, Sonam, Prinos, Panagiotis, Cusimano, Michael D., Das, Sunit, Bernstein, Mark, Arrowsmith, Cheryl H., Mungall, Andrew J., Moore, Richard A., Ma, Yussanne, Gallo, Marco, Lupien, Mathieu, Pugh, Trevor J., Taylor, Michael D., Hirst, Martin, Eaves, Connie J., Simons, Benjamin D., Dirks, Peter B.

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The current consensus on the clinical management of intracranial ependymoma and its distinct molecular variants von Pajtler, Kristian W., Mack, Stephen C., Ramaswamy, Vijay, Smith, Christian A., Witt, Hendrik, Smith, Amy, Hansford, Jordan R., von Hoff, Katja, Wright, Karen D., Hwang, Eugene, Frappaz, Didier, Kanemura, Yonehiro, Massimino, Maura, Faure-Conter, Cécile, Modena, Piergiorgio, Tabori, Uri, Warren, Katherine E., Holland, Eric C., Ichimura, Koichi, Giangaspero, Felice, Castel, David, von Deimling, Andreas, Kool, Marcel, Dirks, Peter B., Grundy, Richard G., Foreman, Nicholas K., Gajjar, Amar, Korshunov, Andrey, Finlay, Jonathan, Gilbertson, Richard J., Ellison, David W., Aldape, Kenneth D., Merchant, Thomas E., Bouffet, Eric, Pfister, Stefan M., Taylor, Michael D.

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Genome-Wide CRISPR-Cas9 Screens Expose Genetic Vulnerabilities and Mechanisms of Temozolomide Sensitivity in Glioblastoma Stem Cells von MacLeod, Graham, Bozek, Danielle A., Rajakulendran, Nishani, Monteiro, Vernon, Ahmadi, Moloud, Steinhart, Zachary, Kushida, Michelle M., Yu, Helen, Coutinho, Fiona J., Cavalli, Florence M.G., Restall, Ian, Hao, Xiaoguang, Hart, Traver, Luchman, H. Artee, Weiss, Samuel, Dirks, Peter B., Angers, Stephane

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Inhibition of Dopamine Receptor D4 Impedes Autophagic Flux, Proliferation, and Survival of Glioblastoma Stem Cells von Dolma, Sonam, Selvadurai, Hayden J., Lan, Xiaoyang, Lee, Lilian, Kushida, Michelle, Voisin, Veronique, Whetstone, Heather, So, Milly, Aviv, Tzvi, Park, Nicole, Zhu, Xueming, Xu, ChangJiang, Head, Renee, Rowland, Katherine J., Bernstein, Mark, Clarke, Ian D., Bader, Gary, Harrington, Lea, Brumell, John H., Tyers, Mike, Dirks, Peter B.

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The white matter is a pro-differentiative niche for glioblastoma von Brooks, Lucy J., Clements, Melanie P., Burden, Jemima J., Kocher, Daniela, Richards, Luca, Devesa, Sara Castro, Zakka, Leila, Woodberry, Megan, Ellis, Michael, Jaunmuktane, Zane, Brandner, Sebastian, Morrison, Gillian, Pollard, Steven M., Dirks, Peter B., Marguerat, Samuel, Parrinello, Simona

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BRAF mutation and CDKN2A deletion define a clinically distinct subgroup of childhood secondary high-grade glioma von Mistry, Matthew, Zhukova, Nataliya, Merico, Daniele, Rakopoulos, Patricia, Krishnatry, Rahul, Shago, Mary, Stavropoulos, James, Alon, Noa, Pole, Jason D, Ray, Peter N, Navickiene, Vilma, Mangerel, Joshua, Remke, Marc, Buczkowicz, Pawel, Ramaswamy, Vijay, Guerreiro Stucklin, Ana, Li, Martin, Young, Edwin J, Zhang, Cindy, Castelo-Branco, Pedro, Bakry, Doua, Laughlin, Suzanne, Shlien, Adam, Chan, Jennifer, Ligon, Keith L, Rutka, James T, Dirks, Peter B, Taylor, Michael D, Greenberg, Mark, Malkin, David, Huang, Annie, Bouffet, Eric, Hawkins, Cynthia E, Tabori, Uri

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Pervasive H3K27 Acetylation Leads to ERV Expression and a Therapeutic Vulnerability in H3K27M Gliomas von Krug, Brian, De Jay, Nicolas, Harutyunyan, Ashot S., Deshmukh, Shriya, Marchione, Dylan M., Guilhamon, Paul, Bertrand, Kelsey C., Mikael, Leonie G., McConechy, Melissa K., Chen, Carol C.L., Khazaei, Sima, Koncar, Robert F., Agnihotri, Sameer, Faury, Damien, Ellezam, Benjamin, Weil, Alexander G., Ursini-Siegel, Josie, De Carvalho, Daniel D., Dirks, Peter B., Lewis, Peter W., Salomoni, Paolo, Lupien, Mathieu, Arrowsmith, Cheryl, Lasko, Paul F., Garcia, Benjamin A., Kleinman, Claudia L., Jabado, Nada, Mack, Stephen C.

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Survival and functional outcomes of molecularly defined childhood posterior fossa ependymoma: Cure at a cost von Zapotocky, Michal, Beera, Kiran, Adamski, Jenny, Laperierre, Normand, Guger, Sharon, Janzen, Laura, Lassaletta, Alvaro, Figueiredo Nobre, Liana, Bartels, Ute, Tabori, Uri, Hawkins, Cynthia, Urbach, Stacey, Tsang, Derek S., Dirks, Peter B., Taylor, Michael D., Bouffet, Eric, Mabbott, Donald J., Ramaswamy, Vijay

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DNA hypermethylation within TERT promoter upregulates TERT expression in cancer von Lee, Donghyun D, Leão, Ricardo, Komosa, Martin, Gallo, Marco, Zhang, Cindy H, Lipman, Tatiana, Remke, Marc, Heidari, Abolfazl, Nunes, Nuno Miguel, Apolónio, Joana D, Price, Aryeh J, De Mello, Ramon Andrade, Dias, João S, Huntsman, David, Hermanns, Thomas, Wild, Peter J, Vanner, Robert, Zadeh, Gelareh, Karamchandani, Jason, Das, Sunit, Taylor, Michael D, Hawkins, Cynthia E, Wasserman, Jonathan D, Figueiredo, Arnaldo, Hamilton, Robert J, Minden, Mark D, Wani, Khalida, Diplas, Bill, Yan, Hai, Aldape, Kenneth, Akbari, Mohammad R, Danesh, Arnavaz, Pugh, Trevor J, Dirks, Peter B, Castelo-Branco, Pedro, Tabori, Uri

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ASCL1 Reorganizes Chromatin to Direct Neuronal Fate and Suppress Tumorigenicity of Glioblastoma Stem Cells von Park, Nicole I., Guilhamon, Paul, Desai, Kinjal, McAdam, Rochelle F., Langille, Ellen, O’Connor, Madlen, Lan, Xiaoyang, Whetstone, Heather, Coutinho, Fiona J., Vanner, Robert J., Ling, Erick, Prinos, Panagiotis, Lee, Lilian, Selvadurai, Hayden, Atwal, Gurnit, Kushida, Michelle, Clarke, Ian D., Voisin, Veronique, Cusimano, Michael D., Bernstein, Mark, Das, Sunit, Bader, Gary, Arrowsmith, Cheryl H., Angers, Stephane, Huang, Xi, Lupien, Mathieu, Dirks, Peter B.

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Prediction model for wheel profile wear and rolling contact fatigue von Dirks, B., Enblom, R.

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Foramen magnum stenosis in a 5-month-old boy with achondroplasia von Malhotra, Armaan K, Parker, Whitney, Dirks, Peter B

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Quiescent Sox2+ Cells Drive Hierarchical Growth and Relapse in Sonic Hedgehog Subgroup Medulloblastoma von Vanner, Robert J., Remke, Marc, Gallo, Marco, Selvadurai, Hayden J., Coutinho, Fiona, Lee, Lilian, Kushida, Michelle, Head, Renee, Morrissy, Sorana, Zhu, Xueming, Aviv, Tzvi, Voisin, Veronique, Clarke, Ian D., Li, Yisu, Mungall, Andrew J., Moore, Richard A., Ma, Yussanne, Jones, Steven J.M., Marra, Marco A., Malkin, David, Northcott, Paul A., Kool, Marcel, Pfister, Stefan M., Bader, Gary, Hochedlinger, Konrad, Korshunov, Andrey, Taylor, Michael D., Dirks, Peter B.

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Cancer stem cells--perspectives on current status and future directions: AACR Workshop on cancer stem cells von Clarke, Michael F, Dick, John E, Dirks, Peter B, Eaves, Connie J, Jamieson, Catriona H M, Jones, D Leanne, Visvader, Jane, Weissman, Irving L, Wahl, Geoffrey M

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Single-cell chromatin profiling of the primitive gut tube reveals regulatory dynamics underlying lineage fate decisions von Smith, Ryan J., Zhang, Hongpan, Hu, Shengen Shawn, Yung, Theodora, Francis, Roshane, Lee, Lilian, Onaitis, Mark W., Dirks, Peter B., Zang, Chongzhi, Kim, Tae-Hee

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