Cryo-electron microscopy structures of the N501Y SARS-CoV-2 spike protein in complex with ACE2 and 2 potent neutralizing antibodies von Zhu, Xing, Mannar, Dhiraj, Srivastava, Shanti S., Berezuk, Alison M., Demers, Jean-Philippe, Saville, James W., Leopold, Karoline, Li, Wei, Dimitrov, Dimiter S., Tuttle, Katharine S., Zhou, Steven, Chittori, Sagar, Subramaniam, Sriram

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Therapeutically targeting glypican-2 via single-domain antibody-based chimeric antigen receptors and immunotoxins in neuroblastoma von Li, Nan, Fu, Haiying, Hewitt, Stephen M., Dimitrov, Dimiter S., Ho, Mitchell

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Eradication of Tumors through Simultaneous Ablation of CD276/B7-H3-Positive Tumor Cells and Tumor Vasculature von Seaman, Steven, Zhu, Zhongyu, Saha, Saurabh, Zhang, Xiaoyan M., Yang, Mi Young, Hilton, Mary Beth, Morris, Karen, Szot, Christopher, Morris, Holly, Swing, Deborah A., Tessarollo, Lino, Smith, Sean W., Degrado, Sylvia, Borkin, Dmitry, Jain, Nareshkumar, Scheiermann, Julia, Feng, Yang, Wang, Yanping, Li, Jinyu, Welsch, Dean, DeCrescenzo, Gary, Chaudhary, Amit, Zudaire, Enrique, Klarmann, Kimberly D., Keller, Jonathan R., Dimitrov, Dimiter S., St. Croix, Brad

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Anti-CD22–chimeric antigen receptors targeting B-cell precursor acute lymphoblastic leukemia von Haso, Waleed, Lee, Daniel W., Shah, Nirali N., Stetler-Stevenson, Maryalice, Yuan, Constance M., Pastan, Ira H., Dimitrov, Dimiter S., Morgan, Richard A., FitzGerald, David J., Barrett, David M., Wayne, Alan S., Mackall, Crystal L., Orentas, Rimas J.

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Therapeutic antibodies, vaccines and antibodyomes von Dimitrov, Dimiter S.

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Structural and biochemical rationale for enhanced spike protein fitness in delta and kappa SARS-CoV-2 variants von Saville, James W., Mannar, Dhiraj, Zhu, Xing, Srivastava, Shanti S., Berezuk, Alison M., Demers, Jean-Philippe, Zhou, Steven, Tuttle, Katharine S., Sekirov, Inna, Kim, Andrew, Li, Wei, Dimitrov, Dimiter S., Subramaniam, Sriram

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Junctional and allele-specific residues are critical for MERS-CoV neutralization by an exceptionally potent germline-like antibody von Ying, Tianlei, Prabakaran, Ponraj, Du, Lanying, Shi, Wei, Feng, Yang, Wang, Yanping, Wang, Lingshu, Li, Wei, Jiang, Shibo, Dimitrov, Dimiter S., Zhou, Tongqing

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Identification of GPC2 as an Oncoprotein and Candidate Immunotherapeutic Target in High-Risk Neuroblastoma von Bosse, Kristopher R., Raman, Pichai, Zhu, Zhongyu, Lane, Maria, Martinez, Daniel, Heitzeneder, Sabine, Rathi, Komal S., Kendsersky, Nathan M., Randall, Michael, Donovan, Laura, Morrissy, Sorana, Sussman, Robyn T., Zhelev, Doncho V., Feng, Yang, Wang, Yanping, Hwang, Jennifer, Lopez, Gonzalo, Harenza, Jo Lynne, Wei, Jun S., Pawel, Bruce, Bhatti, Tricia, Santi, Mariarita, Ganguly, Arupa, Khan, Javed, Marra, Marco A., Taylor, Michael D., Dimitrov, Dimiter S., Mackall, Crystal L., Maris, John M.

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Therapeutically targeting glypican-3 via a conformation-specific single-domain antibody in hepatocellular carcinoma von Feng, Mingqian, Gao, Wei, Wang, Ruoqi, Chen, Weizao, Man, Yan-Gao, Figg, William Douglas, Wang, Xin Wei, Dimitrov, Dimiter S, Ho, Mitchell

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Tumor stroma-targeted antibody-drug conjugate triggers localized anticancer drug release von Szot, Christopher, Saha, Saurabh, Zhang, Xiaoyan M, Zhu, Zhongyu, Hilton, Mary Beth, Morris, Karen, Seaman, Steven, Dunleavey, James M, Hsu, Kuo-Sheng, Yu, Guo-Jun, Morris, Holly, Swing, Deborah A, Haines, Diana C, Wang, Yanping, Hwang, Jennifer, Feng, Yang, Welsch, Dean, DeCrescenzo, Gary, Chaudhary, Amit, Zudaire, Enrique, Dimitrov, Dimiter S, St Croix, Brad

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Editorial: Therapeutic antibody domains against cancer von Zhao, Qi, Li, Wei, Dimitrov, Dimiter S.

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A neutralizing human monoclonal antibody protects against lethal disease in a new ferret model of acute nipah virus infection von Bossart, Katharine N, Zhu, Zhongyu, Middleton, Deborah, Klippel, Jessica, Crameri, Gary, Bingham, John, McEachern, Jennifer A, Green, Diane, Hancock, Timothy J, Chan, Yee-Peng, Hickey, Andrew C, Dimitrov, Dimiter S, Wang, Lin-Fa, Broder, Christopher C

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SARS-CoV-2 variants of concern: spike protein mutational analysis and epitope for broad neutralization von Mannar, Dhiraj, Saville, James W., Sun, Zehua, Zhu, Xing, Marti, Michelle M., Srivastava, Shanti S., Berezuk, Alison M., Zhou, Steven, Tuttle, Katharine S., Sobolewski, Michele D., Kim, Andrew, Treat, Benjamin R., Da Silva Castanha, Priscila Mayrelle, Jacobs, Jana L., Barratt-Boyes, Simon M., Mellors, John W., Dimitrov, Dimiter S., Li, Wei, Subramaniam, Sriram

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Therapeutic Proteins von Dimitrov, Dimiter S.

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Germline-like predecessors of broadly neutralizing antibodies lack measurable binding to HIV-1 envelope glycoproteins: Implications for evasion of immune responses and design of va... von Xiao, Xiaodong, Chen, Weizao, Feng, Yang, Zhu, Zhongyu, Prabakaran, Ponraj, Wang, Yanping, Zhang, Mei-Yun, Longo, Nancy S., Dimitrov, Dimiter S.

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Chimeric antigen receptor-T cells are effective against CEACAM5 expressing non-small cell lung cancer cells resistant to antibody-drug conjugates von Kim, Ye-Jin, Li, Wei, Zhelev, Doncho V, Mellors, John W, Dimitrov, Dimiter S, Baek, Du-San

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Therapeutic Antibodies: Current State and Future Trends – Is a Paradigm Change Coming Soon? von Dimitrov, Dimiter S., Marks, James D.

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Fully human single-domain antibody targeting a highly conserved cryptic epitope on the Nipah virus G protein von Wang, Yulu, Sun, Yifang, Shen, Zhaoling, Wang, Cong, Qian, Jun, Mao, Qiyu, Wang, Yajie, Song, Wenping, Kong, Yu, Zhan, Changyou, Chen, Zhenguo, Dimitrov, Dimiter S., Yang, Zhenlin, Jiang, Shibo, Wu, Fan, Lu, Lu, Ying, Tianlei, Sun, Lei, Wu, Yanling

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Cancer cell survival depends on collagen uptake into tumor-associated stroma von Hsu, Kuo-Sheng, Dunleavey, James M., Szot, Christopher, Yang, Liping, Hilton, Mary Beth, Morris, Karen, Seaman, Steven, Feng, Yang, Lutz, Emily M., Koogle, Robert, Tomassoni-Ardori, Francesco, Saha, Saurabh, Zhang, Xiaoyan M., Zudaire, Enrique, Bajgain, Pradip, Rose, Joshua, Zhu, Zhongyu, Dimitrov, Dimiter S., Cuttitta, Frank, Emenaker, Nancy J., Tessarollo, Lino, St. Croix, Brad

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Construction of a Large Size Human Immunoglobulin Heavy Chain Variable (VH) Domain Library, Isolation and Characterization of Novel Human Antibody VH Domains Targeting PD-L1 and CD... von Sun, Zehua, Li, Wei, Mellors, John W, Orentas, Rimas, Dimitrov, Dimiter S

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