Reagent and Catalyst Capsules: A Chemical Delivery System for Reaction Screening and Parallel Synthesis von Borlinghaus, Niginia, Kaschel, Johannes, Klee, Johanna, Haller, Vanessa, Schetterl, Jasmin, Heitz, Stephanie, Lindner, Tanja, Dietrich, Justin D, Braje, Wilfried M, Jolit, Anais

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The design, synthesis, and evaluation of 8 hybrid DFG-out allosteric kinase inhibitors: A structural analysis of the binding interactions of Gleevec®, Nexavar®, and BIRB-796 von Dietrich, Justin, Hulme, Christopher, Hurley, Laurence H.

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The EED protein–protein interaction inhibitor A-395 inactivates the PRC2 complex von He, Yupeng, Selvaraju, Sujatha, Curtin, Michael L, Jakob, Clarissa G, Zhu, Haizhong, Comess, Kenneth M, Shaw, Bailin, The, Juliana, Lima-Fernandes, Evelyne, Szewczyk, Magdalena M, Cheng, Dong, Klinge, Kelly L, Li, Huan-Qiu, Pliushchev, Marina, Algire, Mikkel A, Maag, David, Guo, Jun, Dietrich, Justin, Panchal, Sanjay C, Petros, Andrew M, Sweis, Ramzi F, Torrent, Maricel, Bigelow, Lance J, Senisterra, Guillermo, Li, Fengling, Kennedy, Steven, Wu, Qin, Osterling, Donald J, Lindley, David J, Gao, Wenqing, Galasinski, Scott, Barsyte-Lovejoy, Dalia, Vedadi, Masoud, Buchanan, Fritz G, Arrowsmith, Cheryl H, Chiang, Gary G, Sun, Chaohong, Pappano, William N

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Emerging molecular diversity from the intra-molecular Ugi reaction: iterative efficiency in medicinal chemistry von Hulme, Christopher, Dietrich, Justin

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Hydrophobic Pockets of HPMC Enable Extremely Short Reaction Times in Water von Petkova, Desislava, Borlinghaus, Niginia, Sharma, Sudripet, Kaschel, Johannes, Lindner, Tanja, Klee, Johanna, Jolit, Anais, Haller, Vanessa, Heitz, Stephanie, Britze, Katarina, Dietrich, Justin, Braje, Wilfried M, Handa, Sachin

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Identification and structure-based drug design of cell-active inhibitors of interleukin 17A at a novel C-terminal site von Goedken, Eric R., Argiriadi, Maria A., Dietrich, Justin D., Petros, Andrew M., Krishnan, Navasona, Panchal, Sanjay C., Qiu, Wei, Wu, Haihong, Zhu, Haizhong, Adams, Ashley M., Bodelle, Pierre M., Goguen, Lucas, Richardson, Paul L., Slivka, Peter F., Srikumaran, Myron, Upadhyay, Anup K., Wu, Bainan, Judge, Russell A., Vasudevan, Anil, Gopalakrishnan, Sujatha M., Cox, Philip B., Stoll, Vincent S., Sun, Chaohong

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Fragment-Based Discovery of an Apolipoprotein E4 (apoE4) Stabilizer von Petros, Andrew M, Korepanova, Alla, Jakob, Clarissa G, Qiu, Wei, Panchal, Sanjay C, Wang, Jie, Dietrich, Justin D, Brewer, Jason T, Pohlki, Frauke, Kling, Andreas, Wilcox, Kyle, Lakics, Viktor, Bahnassawy, Lamiaa, Reinhardt, Peter, Partha, Sarathy Karunan, Bodelle, Pierre M, Lake, Marc, Charych, Erik I, Stoll, Vincent S, Sun, Chaohong, Mohler, Eric G

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Development of Orally Efficacious Allosteric Inhibitors of TNFα via Fragment-Based Drug Design von Dietrich, Justin D, Longenecker, Kenton L, Wilson, Noel S, Goess, Christian, Panchal, Sanjay C, Swann, Steven L, Petros, Andrew M, Hobson, Adrian D, Ihle, David, Song, Danying, Richardson, Paul, Comess, Kenneth M, Cox, Philip B, Dombrowski, Amanda, Sarris, Kathy, Donnelly-Roberts, Diana L, Duignan, David B, Gomtsyan, Arthur, Jung, Paul, Krueger, A Chris, Mathieu, Suzanne, McClure, Andrea, Stoll, Vincent S, Wetter, Jill, Mankovich, John A, Hajduk, Philip J, Vasudevan, Anil, Stoffel, Robert H, Sun, Chaohong

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SAR of amino pyrrolidines as potent and novel protein-protein interaction inhibitors of the PRC2 complex through EED binding von Curtin, Michael L., Pliushchev, Marina A., Li, Huan-Qiu, Torrent, Maricel, Dietrich, Justin D., Jakob, Clarissa G., Zhu, Haizhong, Zhao, Hongyu, Wang, Ying, Ji, Zhiqin, Clark, Richard F., Sarris, Kathy A., Selvaraju, Sujatha, Shaw, Bailin, Algire, Mikkel A., He, Yupeng, Richardson, Paul L., Sweis, Ramzi F., Sun, Chaohong, Chiang, Gary G., Michaelides, Michael R.

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Targeting aPKC disables oncogenic signaling by both the EGFR and the proinflammatory cytokine TNFα in glioblastoma von Kusne, Yael, Carrera-Silva, Eugenio A, Perry, Anthony S, Rushing, Elisabeth J, Mandell, Edward K, Dietrich, Justin D, Errasti, Andrea E, Gibbs, Daniel, Berens, Michael E, Loftus, Joseph C, Hulme, Christopher, Yang, Weiwei, Lu, Zhimin, Aldape, Kenneth, Sanai, Nader, Rothlin, Carla V, Ghosh, Sourav

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Discovery and optimization of novel constrained pyrrolopyridone BET family inhibitors von Fidanze, Steven D., Liu, Dachun, Mantei, Robert A., Hasvold, Lisa A., Pratt, John K., Sheppard, George S., Wang, Le, Holms, James H., Dai, Yujia, Aguirre, Ana, Bogdan, Andrew, Dietrich, Justin D., Marjanovic, Jasmina, Park, Chang H., Hutchins, Charles W., Lin, Xiaoyu, Bui, Mai H., Huang, Xiaoli, Wilcox, Denise, Li, Leiming, Wang, Rongqi, Kovar, Peter, Magoc, Terrance J., Rajaraman, Ganesh, Albert, Daniel H., Shen, Yu, Kati, Warren M., McDaniel, Keith F.

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ERK Crosstalks with 4EBP1 to Activate Cyclin D1 Translation during Quinol-Thioether-Induced Tuberous Sclerosis Renal Cell Carcinoma von Cohen, Jennifer D., Gard, Jaime M. C., Nagle, Raymond B., Dietrich, Justin D., Monks, Terrence J., Lau, Serrine S.

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2,4-Diphenyl-6-trifluoromethyl-2,3-dihydro-1H,5H-pyrrolo[3,4-c]pyrrole-1,3-dione von Sue A. Roberts, Guillermo Martinez-Ariza, Justin Dietrich, Christopher Hulme

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A novel route to synthesize libraries of quinoxalines via Petasis methodology in two synthetic operations von Ayaz, Muhammad, Dietrich, Justin, Hulme, Christopher

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A Strategy for the Synthesis of Sulfonamides on DNA von Liu, Wei, Deng, Wei, Sun, Saisai, Yu, Chunyan, Su, Xubo, Wu, Aliang, Yuan, Youlang, Ma, Zhonglin, Li, Ke, Yang, Hongfang, Peng, Xuanjia, Dietrich, Justin

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A simple, cheap alternative to ‘designer convertible isonitriles’ expedited with microwaves von Hulme, Christopher, Chappeta, Shashi, Dietrich, Justin

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2-Butyl-11-phenyl-5,10-dihydro-1H-benzo[e]imidazo[1,5-a][1,4]diazepine-1,3(2H)-dione von Nichol, Gary S, Gunawan, Steven, Dietrich, Justin, Hulme, Christopher

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2-Propyl 3,3-dibromo-2-hydroxypyrrolidine-1-carboxylate von Nichol, Gary S., Gunawan, Steven, Xu, Zhigang, Dietrich, Justin, Hulme, Christopher

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Concise two-step solution phase syntheses of four novel dihydroquinazoline scaffolds von Dietrich, Justin, Kaiser, Christine, Meurice, Nathalie, Hulme, Christopher

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De Novo Design, Synthesis, and Biological Evaluation of 3,4-Disubstituted Pyrrolidine Sulfonamides as Potent and Selective Glycine Transporter 1 Competitive Inhibitors von Wang, Ying, Zhao, Hongyu, Brewer, Jason T, Li, Huanqiu, Lao, Yanbin, Amberg, Willi, Behl, Berthold, Akritopoulou-Zanze, Irini, Dietrich, Justin, Lange, Udo E. W, Pohlki, Frauke, Hoft, Carolin, Hornberger, Wilfried, Djuric, Stevan W, Sydor, Jens, Mezler, Mario, Relo, Ana Lucia, Vasudevan, Anil

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