Semi-synthetic vNAR libraries screened against therapeutic antibodies primarily deliver anti-idiotypic binders von Könning, Doreen, Rhiel, Laura, Empting, Martin, Grzeschik, Julius, Sellmann, Carolin, Schröter, Christian, Zielonka, Stefan, Dickgießer, Stephan, Pirzer, Thomas, Yanakieva, Desislava, Becker, Stefan, Kolmar, Harald

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From strain engineering to process development: monoclonal antibody production with an unnatural amino acid in Pichia pastoris von Tir, Nora, Heistinger, Lina, Grünwald-Gruber, Clemens, Jakob, Leo A, Dickgiesser, Stephan, Rasche, Nicolas, Mattanovich, Diethard

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A Generic Approach for Miniaturized Unbiased High-Throughput Screens of Bispecific Antibodies and Biparatopic Antibody-Drug Conjugates von Barron, Nadine, Dickgiesser, Stephan, Fleischer, Markus, Bachmann, Angelika-Nicole, Klewinghaus, Daniel, Hannewald, Jens, Ciesielski, Elke, Kusters, Ilja, Hammann, Til, Krause, Volker, Fuchs, Sebastian Winfried, Siegmund, Vanessa, Gross, Alec W, Mueller-Pompalla, Dirk, Krah, Simon, Zielonka, Stefan, Doerner, Achim

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Shark Strikes Twice: Hypervariable Loop 2 of Shark IgNAR Antibody Variable Domains and Its Potential to Function as an Autonomous Paratope von Zielonka, Stefan, Empting, Martin, Könning, Doreen, Grzeschik, Julius, Krah, Simon, Becker, Stefan, Dickgießer, Stephan, Kolmar, Harald

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Cystine-knot peptides targeting cancer-relevant human cytotoxic T lymphocyte-associated antigen 4 (CTLA-4) von Maaß, Franziska, Wüstehube-Lausch, Joycelyn, Dickgießer, Stephan, Valldorf, Bernhard, Reinwarth, Michael, Schmoldt, Hans-Ulrich, Daneschdar, Matin, Avrutina, Olga, Sahin, Ugur, Kolmar, Harald

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Site-Specific Antibody–Drug Conjugation Using Microbial Transglutaminase von Dickgiesser, Stephan, Deweid, Lukas, Kellner, Roland, Kolmar, Harald, Rasche, Nicolas

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EGFR binding Fc domain-drug conjugates: stable and highly potent cytotoxic molecules mediate selective cell killing von Jäger, Sebastian, Dickgiesser, Stephan, Tonillo, Jason, Hecht, Stefan, Kolmar, Harald, Schröter, Christian

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Sortagged anti-EGFR immunoliposomes exhibit increased cytotoxicity on target cells von Wöll, Steffen, Dickgiesser, Stephan, Rasche, Nicolas, Schiller, Stefan, Scherließ, Regina

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Site-Specific Conjugation of Thiol-Reactive Cytotoxic Agents to Nonnative Cysteines of Engineered Monoclonal Antibodies von Dickgiesser, Stephan, Kellner, Roland, Kolmar, Harald, Rasche, Nicolas

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Effect of Conjugation Site and Technique on the Stability and Pharmacokinetics of Antibody-Drug Conjugates von Kaempffe, Anna, Dickgiesser, Stephan, Rasche, Nicolas, Paoletti, Andrea, Bertotti, Elisa, De Salve, Ilse, Sirtori, Federico Riccardi, Kellner, Roland, Könning, Doreen, Hecht, Stefan, Anderl, Jan, Kolmar, Harald, Schröter, Christian

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Site-Specific Conjugation of Native Antibodies Using Engineered Microbial Transglutaminases von Dickgiesser, Stephan, Rieker, Marcel, Mueller-Pompalla, Dirk, Schröter, Christian, Tonillo, Jason, Warszawski, Shira, Raab-Westphal, Sabine, Kühn, Stefanie, Knehans, Tim, Könning, Doreen, Dotterweich, Julia, Betz, Ulrich A. K, Anderl, Jan, Hecht, Stefan, Rasche, Nicolas

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Welding PROxAb Shuttles: A Modular Approach for Generating Bispecific Antibodies via Site-Specific Protein–Protein Conjugation von Lehmann, Tanja, Schneider, Hendrik, Tonillo, Jason, Schanz, Jennifer, Schwarz, Daniel, Schröter, Christian, Jäger, Sebastian, Kolmar, Harald, Hecht, Stefan, Anderl, Jan, Rasche, Nicolas, Rieker, Marcel, Dickgiesser, Stephan

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Efficient spontaneous site-selective cysteine-mediated toxin attachment within a structural loop of antibodies von Stadlmayr, Gerhard, Stracke, Florian, Stadlbauer, Katharina, Rybka, Jakub, Dickgiesser, Stephan, Rasche, Nicolas, Becker, Stefan, Toleikis, Lars, Rüker, Florian, Knopp, Gordana Wozniak

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Engineering bispecific antibodies with defined chain pairing von Krah, Simon, Sellmann, Carolin, Rhiel, Laura, Schröter, Christian, Dickgiesser, Stephan, Beck, Jan, Zielonka, Stefan, Toleikis, Lars, Hock, Björn, Kolmar, Harald, Becker, Stefan

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Potent antitumor activity of anti-HER2 antibody-topoisomerase I inhibitor conjugate based on self-immolative dendritic dimeric-linker von Liubomirski, Yulia, Tiram, Galia, Scomparin, Anna, Gnaim, Samer, Das, Sayantan, Gholap, Sachin, Ge, Liang, Yeini, Eilam, Shelef, Omri, Zauberman, Arie, Berger, Nir, Kalimi, Doron, Toister-Achituv, Mira, Schröter, Christian, Dickgiesser, Stephan, Tonillo, Jason, Shan, Min, Deutsch, Carl, Sweeney-Lasch, Stanley, Shabat, Doron, Satchi-Fainaro, Ronit

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An Apoptosis-Inducing Peptidic Heptad That Efficiently Clusters Death Receptor5 von Valldorf, Bernhard, Fittler, Heiko, Deweid, Lukas, Ebenig, Aileen, Dickgiesser, Stephan, Sellmann, Carolin, Becker, Janine, Zielonka, Stefan, Empting, Martin, Avrutina, Olga, Kolmar, Harald

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An Apoptosis-Inducing Peptidic Heptad That Efficiently Clusters Death Receptor 5 von Valldorf, Bernhard, Fittler, Heiko, Deweid, Lukas, Ebenig, Aileen, Dickgiesser, Stephan, Sellmann, Carolin, Becker, Janine, Zielonka, Stefan, Empting, Martin, Avrutina, Olga, Kolmar, Harald

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Isolation of Anti-Hapten Antibodies by Fluorescence-Activated Cell Sorting of Yeast-Displayed B-Cell Receptor Gene Repertoires von Jäger, Sebastian, Krah, Simon, Könning, Doreen, Rosskopf, Janis, Dickgiesser, Stephan, Rasche, Nicolas, Kolmar, Harald, Hecht, Stefan, Schröter, Christian

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Locked by Design: A Conformationally Constrained Transglutaminase Tag Enables Efficient Site-Specific Conjugation von Siegmund, Vanessa, Schmelz, Stefan, Dickgiesser, Stephan, Beck, Jan, Ebenig, Aileen, Fittler, Heiko, Frauendorf, Holm, Piater, Birgit, Betz, Ulrich A. K., Avrutina, Olga, Scrima, Andrea, Fuchsbauer, Hans-Lothar, Kolmar, Harald

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Self-Assembled Hybrid Aptamer-Fc Conjugates for Targeted Delivery: A Modular Chemoenzymatic Approach von Dickgiesser, Stephan, Rasche, Nicolas, Nasu, Daichi, Middel, Stephen, Hörner, Sebastian, Avrutina, Olga, Diederichsen, Ulf, Kolmar, Harald

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