Evidence for Direct Activation of mTORC2 Kinase Activity by Phosphatidylinositol 3,4,5-Trisphosphate von Gan, Xiaoqing, Wang, Jiyong, Su, Bing, Wu, Dianqing

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LDL receptor-related protein 5 selectively transports unesterified polyunsaturated fatty acids to intracellular compartments von Tang, Wenwen, Luan, Yi, Yuan, Qianying, Li, Ao, Chen, Song, Menacherry, Stanley, Young, Lawrence, Wu, Dianqing

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Genetic Deletion of Catalytic Subunits of AMP-activated Protein Kinase Increases Osteoclasts and Reduces Bone Mass in Young Adult Mice von Kang, Heeseog, Viollet, Benoit, Wu, Dianqing

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Endothelial exocytosis of angiopoietin-2 resulting from CCM3 deficiency contributes to cerebral cavernous malformation von Zhou, Huanjiao Jenny, Qin, Lingfeng, Zhang, Haifeng, Tang, Wenwen, Ji, Weidong, He, Yun, Liang, Xiaoling, Wang, Zongren, Yuan, Qianying, Vortmeyer, Alexander, Toomre, Derek, Fuh, Germaine, Yan, Minghong, Kluger, Martin S, Wu, Dianqing, Min, Wang

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Mechanism of substrate specificity of phosphatidylinositol phosphate kinases von Muftuoglu, Yagmur, Xue, Yi, Gao, Xiang, Wu, Dianqing, Ha, Ya

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GSK3: a multifaceted kinase in Wnt signaling von Wu, Dianqing, Pan, Weijun

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The CUL5 E3 ligase complex negatively regulates central signaling pathways in CD8+ T cells von Liao, Xiaofeng, Li, Wenxue, Zhou, Hongyue, Rajendran, Barani Kumar, Li, Ao, Ren, Jingjing, Luan, Yi, Calderwood, David A., Turk, Benjamin, Tang, Wenwen, Liu, Yansheng, Wu, Dianqing

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Sclerostin Binds to LRP5/6 and Antagonizes Canonical Wnt Signaling von Li, Xiaofeng, Zhang, Yazhou, Kang, Heeseog, Liu, Wenzhong, Liu, Peng, Zhang, Jianghong, Harris, Stephen E., Wu, Dianqing

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Small GTPase ARF6 Is a Coincidence-Detection Code for RPH3A Polarization in Neutrophil Polarization von Ren, Chunguang, Yuan, Qianying, Jian, Xiaoying, Randazzo, Paul A, Tang, Wenwen, Wu, Dianqing

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Essential roles of grp94 in gut homeostasis via chaperoning canonical Wnt pathway von Liu, Bei, Staron, Matthew, Hong, Feng, Wu, Bill X., Sun, Shaoli, Morales, Crystal, Crosson, Craig E., Tomlinson, Stephen, Kim, Ingyu, Wu, Dianqing, Li, Zihai

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Lanosterol Modulates TLR4-Mediated Innate Immune Responses in Macrophages von Araldi, Elisa, Fernández-Fuertes, Marta, Canfrán-Duque, Alberto, Tang, Wenwen, Cline, Gary W., Madrigal-Matute, Julio, Pober, Jordan S., Lasunción, Miguel A., Wu, Dianqing, Fernández-Hernando, Carlos, Suárez, Yajaira

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Wnt5 controls splenic myelopoiesis and neutrophil functional ambivalency during DSS-induced colitis von Luan, Yi, Hu, Jiajia, Wang, Qijun, Wang, Xujun, Li, Wenxue, Qu, Rihao, Yang, Chuan, Rajendran, Barani Kumar, Zhou, Hongyue, Liu, Peng, Zhang, Ningning, Shi, Yu, Liu, Yansheng, Tang, Wenwen, Lu, Jun, Wu, Dianqing

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The structural basis of DKK-mediated inhibition of Wnt/LRP signaling von Bao, Ju, Zheng, Jie J, Wu, Dianqing

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Ubl4A is required for insulin-induced Akt plasma membrane translocation through promotion of Arp2/3-dependent actin branching von Zhao, Yu, Lin, Yuting, Zhang, Honghong, Mañas, Adriana, Tang, Wenwen, Zhang, Yuzhu, Wu, Dianqing, Lin, Anning, Xiang, Jialing

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Endothelial miR-17∼92 cluster negatively regulates arteriogenesis via miRNA-19 repression of WNT signaling von Landskroner-Eiger, Shira, Qiu, Cong, Perrotta, Paola, Siragusa, Mauro, Lee, Monica Y., Ulrich, Victoria, Luciano, Amelia K., Zhuang, Zhen W., Corti, Federico, Simons, Michael, Montgomery, Rusty L., Wu, Dianqing, Yu, Jun, Sessa, William C.

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Regulation of Phosphatidylinositol Kinases and Metabolism by Wnt3a and Dvl von Qin, Yuanbo, Li, Lin, Pan, Weijun, Wu, Dianqing

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Clathrin and AP2 are required for PtdIns(4,5)P2-mediated formation of LRP6 signalosomes von Kim, Ingyu, Pan, Weijun, Jones, Sara A, Zhang, Youxin, Zhuang, Xiaowei, Wu, Dianqing

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Rapamycin treatment dose‐dependently improves the cystic kidney in a new ADPKD mouse model via the mTORC1 and cell‐cycle‐associated CDK1/cyclin axis von Li, Ao, Fan, Song, Xu, Yuchen, Meng, Jialin, Shen, Xufeng, Mao, Jun, Zhang, Li, Zhang, Xiansheng, Moeckel, Gilbert, Wu, Dianqing, Wu, Guanqing, Liang, Chaozhao

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PLCβ2 negatively regulates the inflammatory response to virus infection by inhibiting phosphoinositide-mediated activation of TAK1 von Wang, Lin, Zhou, Yilong, Chen, Zijuan, Sun, Lei, Wu, Juehui, Li, Haohao, Liu, Feng, Wang, Fei, Yang, Chunfu, Yang, Juhao, Leng, Qibin, Zhang, Qingli, Xu, Ajing, Shen, Lisong, Sun, Jinqiao, Wu, Dianqing, Fang, Caiyun, Lu, Haojie, Yan, Dapeng, Ge, Baoxue

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The canonical Wnt signaling antagonist DKK2 is an essential effector of PITX2 function during normal eye development von Gage, Philip J., Qian, Min, Wu, Dianqing, Rosenberg, Kevin I.

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