VHHs as tools for therapeutic protein delivery to the central nervous system von Wouters, Yessica, Jaspers, Tom, Rué, Laura, Serneels, Lutgarde, De Strooper, Bart, Dewilde, Maarten

Volltext

Exploring the Fate of Antibody-Encoding pDNA after Intramuscular Electroporation in Mice von Cuypers, Marie-Lynn, Geukens, Nick, Hollevoet, Kevin, Declerck, Paul, Dewilde, Maarten

Volltext

AAV‐mediated delivery of an anti‐BACE1 VHH alleviates pathology in an Alzheimer's disease model von Marino, Marika, Zhou, Lujia, Rincon, Melvin Y, Callaerts‐Vegh, Zsuzsanna, Verhaert, Jens, Wahis, Jérôme, Creemers, Eline, Yshii, Lidia, Wierda, Keimpe, Saito, Takashi, Marneffe, Catherine, Voytyuk, Iryna, Wouters, Yessica, Dewilde, Maarten, Duqué, Sandra I, Vincke, Cécile, Levites, Yona, Golde, Todd E, Saido, Takaomi C, Muyldermans, Serge, Liston, Adrian, De Strooper, Bart, Holt, Matthew G

Volltext

Clinically relevant dosing and pharmacokinetics of DNA-encoded antibody therapeutics in a sheep model von Hollevoet, Kevin, Thomas, Debby, Compernolle, Griet, Vermeire, Giles, De Smidt, Elien, De Vleeschauwer, Stéphanie, Smith, Trevor R. F., Fisher, Paul D., Dewilde, Maarten, Geukens, Nick, Declerck, Paul

Volltext

Novel Human/Non-Human Primate Cross-Reactive Anti-Transferrin Receptor Nanobodies for Brain Delivery of Biologics von Rué, Laura, Jaspers, Tom, Degors, Isabelle M S, Noppen, Sam, Schols, Dominique, De Strooper, Bart, Dewilde, Maarten

Volltext

Brain-penetrant complement inhibition mitigates neurodegeneration in an Alzheimer's disease mouse model von Zelek, Wioleta M, Bevan, Ryan J, Nimmo, Jacqui, Dewilde, Maarten, De Strooper, Bart, Morgan, B Paul

Volltext

Brain-penetrant complement inhibition mitigates neurodegeneration in an Alzheimer's disease mouse model von Zelek, Wioleta M, Bevan, Ryan J, Nimmo, Jacqui, Dewilde, Maarten, De Strooper, Bart, Morgan, B. Paul

Volltext

Subtle structural differences between human and mouse PAI-1 reveal the basis for biochemical differences von Dewilde, Maarten, Van De Craen, Britt, Compernolle, Griet, Madsen, Jeppe B., Strelkov, Sergei, Gils, Ann, Declerck, Paul J.

Volltext

Comparative study of inhibitory antibody derivatives towards thrombin activatable fibrinolysis inhibitor von Develter, Jan, Dewilde, Maarten, Gils, Ann, Declerck, Paul J.

Volltext

Applicability of cerebral open flow microperfusion and microdialysis to quantify a brain-penetrating nanobody in mice von Custers, Marie-Laure, Wouters, Yessica, Jaspers, Tom, De Bundel, Dimitri, Dewilde, Maarten, Van Eeckhaut, Ann, Smolders, Ilse

Volltext

Anti‐mouse CD98hc nanobodies for brain delivery of a therapeutic moiety von Rué, Laura, Jaspers, Tom, Degors, Isabelle, De Strooper, Bart, Dewilde, Maarten

Volltext

Selective inhibitors of the PSEN1–gamma-secretase complex von Serneels, Lutgarde, Narlawar, Rajeshwar, Perez-Benito, Laura, Municoy, Marti, Guallar, Victor, T’Syen, Dries, Dewilde, Maarten, Bischoff, François, Fraiponts, Erwin, Tresadern, Gary, Roevens, Peter W.M., Gijsen, Harrie J.M., De Strooper, Bart

Volltext

Applicability of cerebral open flow microperfusion and microdialysis to quantify a brain-penetrating nanobody in mice von Custers, Marie-Laure, Wouters, Yessica, Jaspers, Tom, De Bundel, Dimitri, Dewilde, Maarten, Van Eeckhaut, Ann, Smolders, Ilse

Volltext

Selective inhibitors of the PSEN1-gamma-secretase complex von Serneels, Lutgarde, Narlawar, Rajeshwar, Perez-Benito, Laura, Municoy, Marti, Guallar, Victor, T'Syen, Dries, Dewilde, Maarten, Bischoff, François, Fraiponts, Erwin, Tresadern, Gary, Roevens, Peter W.M, Gijsen, Harrie J.M, De Strooper, Bart

Volltext

LRRC37B is a human modifier of voltage-gated sodium channels and axon excitability in cortical neurons von Libé-Philippot, Baptiste, Lejeune, Amélie, Wierda, Keimpe, Louros, Nikolaos, Erkol, Emir, Vlaeminck, Ine, Beckers, Sofie, Gaspariunaite, Vaiva, Bilheu, Angéline, Konstantoulea, Katerina, Nyitrai, Hajnalka, De Vleeschouwer, Matthias, Vennekens, Kristel M, Vidal, Niels, Bird, Thomas W, Soto, Daniela C, Jaspers, Tom, Dewilde, Maarten, Dennis, Megan Y, Rousseau, Frederic, Comoletti, Davide, Schymkowitz, Joost, Theys, Tom, de Wit, Joris, Vanderhaeghen, Pierre

Volltext

VHHs as tools for therapeutic protein delivery to the central nervous system von Wouters, Yessica, Jaspers, Tom, Rue, Laura, Serneels, Lutgarde, De Strooper, Bart, Dewilde, Maarten

Volltext

Novel Human/Non-Human Primate Cross-Reactive Anti-Transferrin Receptor Nanobodies for Brain Delivery of Biologics von Rue, Laura, Jaspers, Tom, Degors, Isabelle M.S, Noppen, Sam, Schols, Dominique, De Strooper, Bart, Dewilde, Maarten

Volltext

Screening and Characterization Strategies for Nanobodies Targeting Membrane Proteins von Veugelen, Sarah, Dewilde, Maarten, De Strooper, Bart, Chávez-Gutiérrez, L

Volltext

Exploring the Fate of Antibody-Encoding pDNA after Intramuscular Electroporation in Mice von Cuypers, Marie-Lynn, Geukens, Nick, Hollevoet, Kevin, Declerck, Paul, Dewilde, Maarten

Volltext

Microfluidic Interfaces for Chronic Bidirectional Access to the Brain von Marcigaglia, Simone, De Plus, Robin, Vandendriessche, Charysse, Schiltz, Eleonore, Cuypers, Marie-Lynn, Cools, Jordi, Hoffman, Luis D, Vandenbroucke, Roosmarijn E, Dewilde, Maarten, Haesler, Sebastian

Volltext