Distinct Tau Prion Strains Propagate in Cells and Mice and Define Different Tauopathies von Sanders, David W., Kaufman, Sarah K., DeVos, Sarah L., Sharma, Apurwa M., Mirbaha, Hilda, Li, Aimin, Barker, Scarlett J., Foley, Alex C., Thorpe, Julian R., Serpell, Louise C., Miller, Timothy M., Grinberg, Lea T., Seeley, William W., Diamond, Marc I.

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The role of microglia in processing and spreading of bioactive tau seeds in Alzheimer's disease von Hopp, Sarah C, Lin, Yang, Oakley, Derek, Roe, Allyson D, DeVos, Sarah L, Hanlon, David, Hyman, Bradley T

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Increased 4R-Tau Induces Pathological Changes in a Human-Tau Mouse Model von Schoch, Kathleen M., DeVos, Sarah L., Miller, Rebecca L., Chun, Seung J., Norrbom, Michaela, Wozniak, David F., Dawson, Hana N., Bennett, C. Frank, Rigo, Frank, Miller, Timothy M.

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Lysosomal functions of progranulin and implications for treatment of frontotemporal dementia von Simon, Matthew J., Logan, Todd, DeVos, Sarah L., Di Paolo, Gilbert

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Heparan sulfate proteoglycans mediate internalization and propagation of specific proteopathic seeds von Holmes, Brandon B, DeVos, Sarah L, Kfoury, Najla, Li, Mei, Jacks, Rachel, Yanamandra, Kiran, Ouidja, Mohand O, Brodsky, Frances M, Marasa, Jayne, Bagchi, Devika P, Kotzbauer, Paul T, Miller, Timothy M, Papy-Garcia, Dulce, Diamond, Marc I

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Neuronal uptake and propagation of a rare phosphorylated high-molecular-weight tau derived from Alzheimer’s disease brain von Takeda, Shuko, Wegmann, Susanne, Cho, Hansang, DeVos, Sarah L., Commins, Caitlin, Roe, Allyson D., Nicholls, Samantha B., Carlson, George A., Pitstick, Rose, Nobuhara, Chloe K., Costantino, Isabel, Frosch, Matthew P., Müller, Daniel J., Irimia, Daniel, Hyman, Bradley T.

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Antisense Oligonucleotides: Treating Neurodegeneration at the Level of RNA von DeVos, Sarah L., Miller, Timothy M.

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Characterization of TauC3 antibody and demonstration of its potential to block tau propagation von Nicholls, Samantha B, DeVos, Sarah L, Commins, Caitlin, Nobuhara, Chloe, Bennett, Rachel E, Corjuc, Diana L, Maury, Eduardo, Eftekharzadeh, Bahareh, Akingbade, Ololade, Fan, Zhanyun, Roe, Allyson D, Takeda, Shuko, Wegmann, Susanne, Hyman, Bradley T

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Synaptic Tau Seeding Precedes Tau Pathology in Human Alzheimer's Disease Brain von DeVos, Sarah L, Corjuc, Bianca T, Oakley, Derek H, Nobuhara, Chloe K, Bannon, Riley N, Chase, Alison, Commins, Caitlin, Gonzalez, Jose A, Dooley, Patrick M, Frosch, Matthew P, Hyman, Bradley T

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Enhanced Tau Aggregation in the Presence of Amyloid β von Bennett, Rachel E, DeVos, Sarah L, Dujardin, Simon, Corjuc, Bianca, Gor, Rucha, Gonzalez, Jose, Roe, Allyson D, Frosch, Matthew P, Pitstick, Rose, Carlson, George A, Hyman, Bradley T

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Tau Protein Disrupts Nucleocytoplasmic Transport in Alzheimer’s Disease von Eftekharzadeh, Bahareh, Daigle, J. Gavin, Kapinos, Larisa E., Coyne, Alyssa, Schiantarelli, Julia, Carlomagno, Yari, Cook, Casey, Miller, Sean J., Dujardin, Simon, Amaral, Ana S., Grima, Jonathan C., Bennett, Rachel E., Tepper, Katharina, DeTure, Michael, Vanderburg, Charles R., Corjuc, Bianca T., DeVos, Sarah L., Gonzalez, Jose Antonio, Chew, Jeannie, Vidensky, Svetlana, Gage, Fred H., Mertens, Jerome, Troncoso, Juan, Mandelkow, Eckhard, Salvatella, Xavier, Lim, Roderick Y.H., Petrucelli, Leonard, Wegmann, Susanne, Rothstein, Jeffrey D., Hyman, Bradley T.

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Pathogenic tau accelerates aging-associated activation of transposable elements in the mouse central nervous system von Ramirez, Paulino, Zuniga, Gabrielle, Sun, Wenyan, Beckmann, Adrian, Ochoa, Elizabeth, DeVos, Sarah L., Hyman, Bradley, Chiu, Gabriel, Roy, Ethan R., Cao, Wei, Orr, Miranda, Buggia-Prevot, Virginie, Ray, William J., Frost, Bess

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Direct intraventricular delivery of drugs to the rodent central nervous system von DeVos, Sarah L, Miller, Timothy M

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Tau Antibody Targeting Pathological Species Blocks Neuronal Uptake and Interneuron Propagation of Tau in Vitro von Nobuhara, Chloe K., DeVos, Sarah L., Commins, Caitlin, Wegmann, Susanne, Moore, Benjamin D., Roe, Allyson D., Costantino, Isabel, Frosch, Matthew P., Pitstick, Rose, Carlson, George A., Hock, Christoph, Nitsch, Roger M., Montrasio, Fabio, Grimm, Jan, Cheung, Anne E., Dunah, Anthone W., Wittmann, Marion, Bussiere, Thierry, Weinreb, Paul H., Hyman, Bradley T., Takeda, Shuko

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Antisense reduction of tau in adult mice protects against seizures von DeVos, Sarah L, Goncharoff, Dustin K, Chen, Guo, Kebodeaux, Carey S, Yamada, Kaoru, Stewart, Floy R, Schuler, Dorothy R, Maloney, Susan E, Wozniak, David F, Rigo, Frank, Bennett, C Frank, Cirrito, John R, Holtzman, David M, Miller, Timothy M

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In vivo rate-determining steps of tau seed accumulation in Alzheimer's disease von Meisl, Georg, Hidari, Eric, Allinson, Kieren, Rittman, Timothy, DeVos, Sarah L, Sanchez, Justin S, Xu, Catherine K, Duff, Karen E, Johnson, Keith A, Rowe, James B, Hyman, Bradley T, Knowles, Tuomas P J, Klenerman, David

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Seed-competent high-molecular-weight tau species accumulates in the cerebrospinal fluid of Alzheimer's disease mouse model and human patients von Takeda, Shuko, Commins, Caitlin, DeVos, Sarah L., Nobuhara, Chloe K., Wegmann, Susanne, Roe, Allyson D., Costantino, Isabel, Fan, Zhanyun, Nicholls, Samantha B., Sherman, Alexis E., Trisini Lipsanopoulos, Ana T., Scherzer, Clemens R., Carlson, George A., Pitstick, Rose, Peskind, Elaine R., Raskind, Murray A., Li, Ge, Montine, Thomas J., Frosch, Matthew P., Hyman, Bradley T.

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Tau reduction in the presence of amyloid-β prevents tau pathology and neuronal death in vivo von DeVos, Sarah L, Corjuc, Bianca T, Commins, Caitlin, Dujardin, Simon, Bannon, Riley N, Corjuc, Diana, Moore, Benjamin D, Bennett, Rachel E, Jorfi, Mehdi, Gonzales, Jose A, Dooley, Patrick M, Roe, Allyson D, Pitstick, Rose, Irimia, Daniel, Frosch, Matthew P, Carlson, George A, Hyman, Bradley T

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Removing endogenous tau does not prevent tau propagation yet reduces its neurotoxicity von Wegmann, Susanne, Maury, Eduardo A, Kirk, Molly J, Saqran, Lubna, Roe, Allyson, DeVos, Sarah L, Nicholls, Samantha, Fan, Zhanyun, Takeda, Shuko, Cagsal-Getkin, Ozge, William, Christopher M, Spires-Jones, Tara L, Pitstick, Rose, Carlson, George A, Pooler, Amy M, Hyman, Bradley T

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Tau at the Crossroads between Neurotoxicity and Neuroprotection von DeVos, Sarah L., Hyman, Bradley T.

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