RASA1 and NF1 are Preferentially Co-Mutated and Define A Distinct Genetic Subset of Smoking-Associated Non-Small Cell Lung Carcinomas Sensitive to MEK Inhibition von Hayashi, Takuo, Desmeules, Patrice, Smith, Roger S, Drilon, Alexander, Somwar, Romel, Ladanyi, Marc

Volltext

PARP Inhibitor Activity Correlates with SLFN11 Expression and Demonstrates Synergy with Temozolomide in Small Cell Lung Cancer von Lok, Benjamin H, Gardner, Eric E, Schneeberger, Valentina E, Ni, Andy, Desmeules, Patrice, Rekhtman, Natasha, de Stanchina, Elisa, Teicher, Beverly A, Riaz, Nadeem, Powell, Simon N, Poirier, John T, Rudin, Charles M

Volltext

SMARCA4-Deficient Thoracic Sarcomatoid Tumors Represent Primarily Smoking-Related Undifferentiated Carcinomas Rather Than Primary Thoracic Sarcomas von Rekhtman, Natasha, Montecalvo, Joseph, Chang, Jason C., Alex, Deepu, Ptashkin, Ryan N., Ai, Ni, Sauter, Jennifer L., Kezlarian, Brie, Jungbluth, Achim, Desmeules, Patrice, Beras, Amanda, Bishop, Justin A., Plodkowski, Andrew J., Gounder, Mrinal M., Schoenfeld, Adam J., Namakydoust, Azadeh, Li, Bob T., Rudin, Charles M., Riely, Gregory J., Jones, David R., Ladanyi, Marc, Travis, William D.

Volltext

V-domain Ig-containing suppressor of T-cell activation (VISTA), a potentially targetable immune checkpoint molecule, is highly expressed in epithelioid malignant pleural mesothelio... von Muller, Stephanie, Victoria Lai, W., Adusumilli, Prasad S., Desmeules, Patrice, Frosina, Denise, Jungbluth, Achim, Ni, Ai, Eguchi, Takashi, Travis, William D., Ladanyi, Marc, Zauderer, Marjorie G., Sauter, Jennifer L.

Volltext

Comprehensive Molecular and Clinicopathologic Analysis of 200 Pulmonary Invasive Mucinous Adenocarcinomas Identifies Distinct Characteristics of Molecular Subtypes von Chang, Jason C, Offin, Michael, Falcon, Christina, Brown, David, Houck-Loomis, Brian R, Meng, Fanli, Rudneva, Vasilisa A, Won, Helen H, Amir, Sharon, Montecalvo, Joseph, Desmeules, Patrice, Kadota, Kyuichi, Adusumilli, Prasad S, Rusch, Valerie W, Teed, Sarah, Sabari, Joshua K, Benayed, Ryma, Nafa, Khedoudja, Borsu, Laetitia, Li, Bob T, Schram, Alison M, Arcila, Maria E, Travis, William D, Ladanyi, Marc, Drilon, Alexander, Rekhtman, Natasha

Volltext

Response to ERBB3-Directed Targeted Therapy in NRG1 -Rearranged Cancers von Drilon, Alexander, Somwar, Romel, Mangatt, Biju P, Edgren, Henrik, Desmeules, Patrice, Ruusulehto, Anja, Smith, Roger S, Delasos, Lukas, Vojnic, Morana, Plodkowski, Andrew J, Sabari, Joshua, Ng, Kenneth, Montecalvo, Joseph, Chang, Jason, Tai, Huichun, Lockwood, William W, Martinez, Victor, Riely, Gregory J, Rudin, Charles M, Kris, Mark G, Arcila, Maria E, Matheny, Christopher, Benayed, Ryma, Rekhtman, Natasha, Ladanyi, Marc, Ganji, Gopinath

Volltext

Stage IV lung carcinoids: spectrum and evolution of proliferation rate, focusing on variants with elevated proliferation indices von Rekhtman, Natasha, Desmeules, Patrice, Litvak, Anna M., Pietanza, Maria C., Santos-Zabala, Maria Lauren, Ni, Ai, Montecalvo, Joseph, Chang, Jason C., Beras, Amanda, Preeshagul, Isabel R., Sabari, Joshua K., Rudin, Charles M., Ladanyi, Marc, Klimstra, David S., Travis, William D., Lai, Wei-Chu

Volltext

Impact of Specimen Characteristics on PD-L1 Testing in Non–Small Cell Lung Cancer: Validation of the IASLC PD-L1 Testing Recommendations von Gagné, Andréanne, Wang, Emily, Bastien, Nathalie, Orain, Michèle, Desmeules, Patrice, Pagé, Sylvain, Trahan, Sylvain, Couture, Christian, Joubert, David, Joubert, Philippe

Volltext

Transcriptomic data helps refining classification of pulmonary carcinoid tumors with increased mitotic counts von Sazonova, Olga, Manem, Venkata, Orain, Michèle, Khoshkrood-Mansoori, Babak, Gaudreault, Nathalie, Desmeules, Patrice, Bossé, Yohan, Joubert, Philippe

Volltext

BCG vaccination provides protection against IAV but not SARS-CoV-2 von Kaufmann, Eva, Khan, Nargis, Tran, Kim A., Ulndreaj, Antigona, Pernet, Erwan, Fontes, Ghislaine, Lupien, Andréanne, Desmeules, Patrice, McIntosh, Fiona, Abow, Amina, Moorlag, Simone J.C.F.M., Debisarun, Priya, Mossman, Karen, Banerjee, Arinjay, Karo-Atar, Danielle, Sadeghi, Mina, Mubareka, Samira, Vinh, Donald C., King, Irah L., Robbins, Clinton S., Behr, Marcel A., Netea, Mihai G., Joubert, Philippe, Divangahi, Maziar

Volltext

Feasibility of endobronchial ultrasound transbronchial needle aspiration for massively parallel next-generation sequencing in thoracic cancer patients von Turner, Simon R., Buonocore, Darren, Desmeules, Patrice, Rekhtman, Natasha, Dogan, Snjezana, Lin, Oscar, Arcila, Maria E., Jones, David R., Huang, James

Volltext

Retrospective Assessment of Complementary Liquid Biopsy on Tissue Single-Gene Testing for Tumor Genotyping in Advanced NSCLC von Desmeules, Patrice, Dusselier, Matthieu, Bouffard, Cédrik, Bafaro, Josée, Fortin, Marc, Labbé, Catherine, Joubert, Philippe

Volltext

Canadian Consensus for Biomarker Testing and Treatment of TRK Fusion Cancer in Adults von Bebb, D Gwyn, Banerji, Shantanu, Blais, Normand, Desmeules, Patrice, Gill, Sharlene, Grin, Andrea, Feilotter, Harriet, Hansen, Aaron R, Hyrcza, Martin, Krzyzanowska, Monika, Melosky, Barbara, Noujaim, Jonathan, Purgina, Bibiana, Ruether, Dean, Simmons, Christine E, Soulieres, Denis, Torlakovic, Emina Emilia, Tsao, Ming-Sound

Volltext

Omega-3 Fatty Acids Survey in Men under Active Surveillance for Prostate Cancer: from Intake to Prostate Tissue Level von Moussa, Hanane, Nguile-Makao, Molière, Robitaille, Karine, Guertin, Marie-Hélène, Allaire, Janie, Pelletier, Jean-François, Moreel, Xavier, Gevariya, Nikunj, Diorio, Caroline, Desmeules, Patrice, Têtu, Bernard, Lamarche, Benoît, Julien, Pierre, Fradet, Vincent

Volltext

Consensus Recommendations to Optimize the Detection and Reporting of NTRK Gene Fusions by RNA-Based Next-Generation Sequencing von Stockley, Tracy L, Lo, Bryan, Box, Adrian, Gomez Corredor, Andrea, DeCoteau, John, Desmeules, Patrice, Feilotter, Harriet, Grafodatskaya, Daria, Hawkins, Cynthia, Huang, Weei Yuarn, Izevbaye, Iyare, Lepine, Guylaine, Papadakis, Andreas I, Park, Paul C, Sheffield, Brandon S, Tran-Thanh, Danh, Yip, Stephen, Sound Tsao, Ming

Volltext

Performance of an RNA-Based Next-Generation Sequencing Assay for Combined Detection of Clinically Actionable Fusions and Hotspot Mutations in NSCLC von Desmeules, Patrice, Boudreau, Dominique K., Bastien, Nathalie, Boulanger, Marie-Chloé, Bossé, Yohan, Joubert, Philippe, Couture, Christian

Volltext

Prognostic significance of TIMP-2, MMP-2, and MMP-9 on high-grade serous ovarian carcinoma using digital image analysis von Desmeules, Patrice, MD, MSc, Trudel, Dominique, MD, PhD, Turcotte, Stéphane, MSc, Sirois, Jennifer, MD, Plante, Marie, MD, Grégoire, Jean, MD, Renaud, Marie-Claude, MD, Orain, Michèle, MLT, Têtu, Bernard, MD, Bairati, Isabelle, MD, PhD

Volltext

Canadian Consensus Recommendations on the Management of MET -Altered NSCLC von Cheema, Parneet K, Banerji, Shantanu O, Blais, Normand, Chu, Quincy S-C, Desmeules, Patrice, Juergens, Rosalyn A, Leighl, Natasha B, Sheffield, Brandon S, Wheatley-Price, Paul F, Melosky, Barbara L

Volltext

Comparison of digital image analysis and visual scoring of KI-67 in prostate cancer prognosis after prostatectomy von Desmeules, Patrice, Hovington, Hélène, Nguilé-Makao, Molière, Léger, Caroline, Caron, André, Lacombe, Louis, Fradet, Yves, Têtu, Bernard, Fradet, Vincent

Volltext

High Yield of RNA Sequencing for Targetable Kinase Fusions in Lung Adenocarcinomas with No Mitogenic Driver Alteration Detected by DNA Sequencing and Low Tumor Mutation Burden von Benayed, Ryma, Offin, Michael, Mullaney, Kerry, Sukhadia, Purvil, Rios, Kelly, Desmeules, Patrice, Ptashkin, Ryan, Won, Helen, Chang, Jason, Halpenny, Darragh, Schram, Alison M, Rudin, Charles M, Hyman, David M, Arcila, Maria E, Berger, Michael F, Zehir, Ahmet, Kris, Mark G, Drilon, Alexander, Ladanyi, Marc

Volltext