Glyburide inhibits the Cryopyrin/Nalp3 inflammasome von Lamkanfi, Mohamed, Mueller, James L, Vitari, Alberto C, Misaghi, Shahram, Fedorova, Anna, Deshayes, Kurt, Lee, Wyne P, Hoffman, Hal M, Dixit, Vishva M

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Disruption of XIAP-RIP2 Association Blocks NOD2-Mediated Inflammatory Signaling von Goncharov, Tatiana, Hedayati, Stefanie, Mulvihill, Melinda M., Izrael-Tomasevic, Anita, Zobel, Kerry, Jeet, Surinder, Fedorova, Anna V., Eidenschenk, Celine, deVoss, Jason, Yu, Kebing, Shaw, Andrey S., Kirkpatrick, Donald S., Fairbrother, Wayne J., Deshayes, Kurt, Vucic, Domagoj

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By Any Means Necessary: Discovering a Bcl-xL Specific Domain von Deshayes, Kurt D.

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Smac Mimetic Bypasses Apoptosis Resistance in FADD- or Caspase-8-Deficient Cells by Priming for Tumor Necrosis Factor α-Induced Necroptosis von Laukens, Bram, Jennewein, Claudia, Schenk, Barbara, Vanlangenakker, Nele, Schier, Alexander, Cristofanon, Silvia, Zobel, Kerry, Deshayes, Kurt, Vucic, Domagoj, Jeremias, Irmela, Bertrand, Mathieu J.M, Vandenabeele, Peter, Fulda, Simone

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Improved Quantitative Mass Spectrometry Methods for Characterizing Complex Ubiquitin Signals von Phu, Lilian, Izrael-Tomasevic, Anita, Matsumoto, Marissa L., Bustos, Daisy, Dynek, Jasmin N., Fedorova, Anna V., Bakalarski, Corey E., Arnott, David, Deshayes, Kurt, Dixit, Vishva M., Kelley, Robert F., Vucic, Domagoj, Kirkpatrick, Donald S.

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Requirement of Nuclear Factor κB for Smac Mimetic–Mediated Sensitization of Pancreatic Carcinoma Cells for Gemcitabine-Induced Apoptosis von Stadel, Dominic, Cristofanon, Silvia, Abhari, Behnaz Ahangarian, Deshayes, Kurt, Zobel, Kerry, Vucic, Domagoj, Debatin, Klaus-Michael, Fulda, Simone

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Antagonism of c-IAP and XIAP Proteins Is Required for Efficient Induction of Cell Death by Small-Molecule IAP Antagonists von Ndubaku, Chudi, Varfolomeev, Eugene, Wang, Lan, Zobel, Kerry, Lau, Kevin, Elliott, Linda O, Maurer, Brigitte, Fedorova, Anna V, Dynek, Jasmin N, Koehler, Michael, Hymowitz, Sarah G, Tsui, Vickie, Deshayes, Kurt, Fairbrother, Wayne J, Flygare, John A, Vucic, Domagoj

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Characterization of ML-IAP protein stability and physiological role in vivo von Varfolomeev, Eugene, Moradi, Elham, Dynek, Jasmin N, Zha, Jiping, Fedorova, Anna V, Deshayes, Kurt, Fairbrother, Wayne J, Newton, Kim, Le Couter, Jennifer, Vucic, Domagoj

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SMAC Negatively Regulates the Anti-apoptotic Activity of Melanoma Inhibitor of Apoptosis (ML-IAP) von Vucic, Domagoj, Deshayes, Kurt, Ackerly, Heidi, Pisabarro, Maria Teresa, Kadkhodayan, Saloumeh, Fairbrother, Wayne J., Dixit, Vishva M.

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Novel Bcl-2 Homology-3 Domain-like Sequences Identified from Screening Randomized Peptide Libraries for Inhibitors of the Pro-survival Bcl-2 Proteins von Lee, Erinna F., Fedorova, Anna, Zobel, Kerry, Boyle, Michelle J., Yang, Hong, Perugini, Matthew A., Colman, Peter M., Huang, David C.S., Deshayes, Kurt, Fairlie, W.Douglas

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cIAP1 and TAK1 protect cells from TNF-induced necrosis by preventing RIP1 RIP3-dependent reactive oxygen species production von Vanlangenakker, N, Vanden Berghe, T, Bogaert, P, Laukens, B, Zobel, K, Deshayes, K, Vucic, D, Fulda, S, Vandenabeele, P, Bertrand, M J M

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Crystal Structure of Human Insulin-like Growth Factor-1:  Detergent Binding Inhibits Binding Protein Interactions von Vajdos, Felix F, Ultsch, Mark, Schaffer, Michelle L, Deshayes, Kurt D, Liu, Jun, Skelton, Nicholas J, de Vos, Abraham M

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c-IAP1 and c-IAP2 Are Critical Mediators of Tumor Necrosis Factor α (TNFα)-induced NF-κB Activation von Varfolomeev, Eugene, Goncharov, Tatiana, Fedorova, Anna V., Dynek, Jasmin N., Zobel, Kerry, Deshayes, Kurt, Fairbrother, Wayne J., Vucic, Domagoj

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Cellular inhibitors of apoptosis are global regulators of NF-κB and MAPK activation by members of the TNF family of receptors von Varfolomeev, Eugene, Goncharov, Tatiana, Maecker, Heather, Zobel, Kerry, Kömüves, László G, Deshayes, Kurt, Vucic, Domagoj

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IAP Antagonists Induce Autoubiquitination of c-IAPs, NF-κB Activation, and TNFα-Dependent Apoptosis von Varfolomeev, Eugene, Blankenship, John W., Wayson, Sarah M., Fedorova, Anna V., Kayagaki, Nobuhiko, Garg, Parie, Zobel, Kerry, Dynek, Jasmin N., Elliott, Linda O., Wallweber, Heidi J.A., Flygare, John A., Fairbrother, Wayne J., Deshayes, Kurt, Dixit, Vishva M., Vucic, Domagoj

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Structure-guided design of a selective BCL-XL inhibitor von Lessene, Guillaume, Czabotar, Peter E, Sleebs, Brad E, Zobel, Kerry, Lowes, Kym N, Adams, Jerry M, Baell, Jonathan B, Colman, Peter M, Deshayes, Kurt, Fairbrother, Wayne J, Flygare, John A, Gibbons, Paul, Kersten, Wilhelmus J A, Kulasegaram, Sanji, Moss, Rebecca M, Parisot, John P, Smith, Brian J, Street, Ian P, Yang, Hong, Huang, David C S, Watson, Keith G

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c-IAP1 and UbcH5 promote K11-linked polyubiquitination of RIP1 in TNF signalling von Dynek, Jasmin N, Goncharov, Tatiana, Dueber, Erin C, Fedorova, Anna V, Izrael-Tomasevic, Anita, Phu, Lilian, Helgason, Elizabeth, Fairbrother, Wayne J, Deshayes, Kurt, Kirkpatrick, Donald S, Vucic, Domagoj

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OTUB1 modulates c-IAP1 stability to regulate signalling pathways von Goncharov, Tatiana, Niessen, Kyle, de Almagro, Maria Cristina, Izrael-Tomasevic, Anita, Fedorova, Anna V, Varfolomeev, Eugene, Arnott, David, Deshayes, Kurt, Kirkpatrick, Donald S, Vucic, Domagoj

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Antagonists Induce a Conformational Change in cIAP1 That Promotes Autoubiquitination von Dueber, Erin C., Schoeffler, Allyn J., Lingel, Andreas, Elliott, J. Michael, Fedorova, Anna V., Giannetti, Anthony M., Zobel, Kerry, Maurer, Brigitte, Varfolomeev, Eugene, Wu, Ping, Wallweber, Heidi J. A., Hymowitz, Sarah G., Deshayes, Kurt, Vucic, Domagoj, Fairbrother, Wayne J.

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Stabilizing the Pro-Apoptotic BimBH3 Helix (BimSAHB) Does Not Necessarily Enhance Affinity or Biological Activity von Okamoto, Toru, Zobel, Kerry, Fedorova, Anna, Quan, Clifford, Yang, Hong, Fairbrother, Wayne J, Huang, David C. S, Smith, Brian J, Deshayes, Kurt, Czabotar, Peter E

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