Alterations in the PI3K Pathway Drive Resistance to MET Inhibitors in NSCLC Harboring MET Exon 14 Skipping Mutations von Jamme, Philippe, Fernandes, Marie, Copin, Marie-Christine, Descarpentries, Clotilde, Escande, Fabienne, Morabito, Angela, Grégoire, Valérie, Jamme, Matthieu, Baldacci, Simon, Tulasne, David, Kherrouche, Zoulika, Cortot, Alexis B.

Volltext

Optimization of Routine Testing for MET Exon 14 Splice Site Mutations in NSCLC Patients von Descarpentries, Clotilde, Leprêtre, Frédéric, Escande, Fabienne, Kherrouche, Zoulika, Figeac, Martin, Sebda, Shéhérazade, Baldacci, Simon, Grégoire, Valérie, Jamme, Philippe, Copin, Marie-Christine, Tulasne, David, Cortot, Alexis B.

Volltext

Complete and prolonged response to anti-PD1 therapy in an ALK rearranged lung adenocarcinoma von Baldacci, Simon, Grégoire, Valérie, Patrucco, Enrico, Chiarle, Roberto, Jamme, Philippe, Wasielewski, Eric, Descarpentries, Clotilde, Copin, Marie-Christine, Awad, Mark M, Cortot, Alexis B

Volltext

MET exon 14 skipping mutation is a hepatocyte growth factor (HGF)-dependent oncogenic driver in vitro and in humanised HGF knock-in mice von Fernandes, Marie, Hoggard, Brynna, Jamme, Philippe, Paget, Sonia, Truong, Marie-José, Grégoire, Valérie, Vinchent, Audrey, Descarpentries, Clotilde, Morabito, Angela, Stanislovas, Justas, Farage, Enoir, Meneboo, Jean-Pascal, Sebda, Shéhérazade, Bouchekioua-Bouzaghou, Katia, Nollet, Marie, Humez, Sarah, Perera, Timothy, Fromme, Paul, Grumolato, Luca, Figeac, Martin, Copin, Marie-Christine, Tulasne, David, Cortot, Alexis B, Kermorgant, Stéphanie, Kherrouche, Zoulika

Volltext

Relevance of Detection of Mechanisms of Resistance to ALK Inhibitors in ALK-Rearranged NSCLC in Routine Practice von Jamme, Philippe, Descarpentries, Clotilde, Gervais, Radj, Dansin, Eric, Wislez, Marie, Grégoire, Valérie, Richard, Nicolas, Baldacci, Simon, Rabbe, Nathalie, Kyheng, Maeva, Kherrouche, Zoulika, Escande, Fabienne, Copin, Marie Christine, Cortot, Alexis B.

Volltext

Tyrosine kinase inhibitors induce down-regulation of c-Kit by targeting the ATP pocket von D'allard, Diane, Gay, Julie, Descarpentries, Clotilde, Frisan, Emilie, Adam, Kevin, Verdier, Frederique, Floquet, Célia, Dubreuil, Patrice, Lacombe, Catherine, Fontenay, Michaela, Mayeux, Patrick, Kosmider, Olivier

Volltext

Exon 14 Deleted MET Receptor as a New Biomarker and Target in Cancers von Cortot, Alexis B, Kherrouche, Zoulika, Descarpentries, Clotilde, Wislez, Marie, Baldacci, Simon, Furlan, Alessandro, Tulasne, David

Volltext

Response to Capmatinib in a MET Fusion-positive Cholangiocarcinoma von Turpin, Anthony, Descarpentries, Clotilde, Grégoire, Valérie, Farchi, Olivier, Cortot, Alexis B, Jamme, Philippe

Volltext

MET kinase mutations in lung cancer patients von Kalmuk, Louise, Descarpentries, Clotilde, Mascaux, Celine, Munck, Camille, Kherrouche, Zoulika, Wasielewski, Eric, Ulmer, Lucie, Farchi, Olivier, Escande, Fabienne, Beau-Faller, Michele, Cortot, Alexis B

Volltext

Transforming properties of MET receptor exon 14 skipping can be recapitulated by loss of the CBL ubiquitin ligase binding site von Fernandes, Marie, Paget, Sonia, Kherrouche, Zoulika, Truong, Marie-José, Vinchent, Audrey, Meneboo, Jean-Pascal, Sebda, Shéhérazade, Werkmeister, Elisabeth, Descarpentries, Clotilde, Figeac, Martin, Cortot, Alexis B, Tulasne, David

Volltext

Capmatinib efficacy for METex14 non-small cell lung cancer patients: Results of the IFCT-2104 CAPMATU study von Ferreira, Marion, Swalduz, Aurélie, Greillier, Laurent, du Rusquec, Pauline, Curcio, Hubert, Raimbourg, Judith, Toffart, Anne-Claire, Gounant, Valérie, Couraud, Sebastien, De Chabot, Gonzague, Friard, Sylvie, Hureaux, José, Jeannin, Gaëlle, Odier, Luc, Ricordel, Charles, Wislez, Marie, Descarpentries, Clotilde, Herbreteau, Guillaume, Missy, Pascale, Morin, Franck, Westeel, Virginie, Cortot, Alexis B.

Volltext

Characterization of 164 patients with NRAS mutated non-small cell lung cancer (NSCLC) von Dehem, Agathe, Mazieres, Julien, Chour, Ali, Guisier, Florian, Ferreira, Marion, Boussageon, Maxime, Girard, Nicolas, Moro-Sibilot, Denis, Cadranel, Jacques, Zalcman, Gérard, Ricordel, Charles, Wislez, Marie, Munck, Camille, Poulet, Claire, Gauvain, Clément, Descarpentries, Clotilde, Wasielewski, Eric, Cortot, Alexis B., Baldacci, Simon

Volltext

High MET Overexpression Does Not Predict the presence of MET exon 14 Splice Mutations in NSCLC: Results From the IFCT PREDICT.amm study von Baldacci, Simon, Figeac, Martin, Antoine, Martine, Descarpentries, Clotilde, Kherrouche, Zoulika, Jamme, Philippe, Copin, Marie-Christine, Tulasne, David, Nanni, Isabelle, Beau-Faller, Michèle, Melaabi, Samia, Levallet, Guénaëlle, Quoix, Elisabeth, Moro-Sibilot, Denis, Friard, Sylvie, Missy, Pascale, Barlesi, Fabrice, Cadranel, Jacques, Cortot, Alexis B.

Volltext

Abstract 3683: MET exon 14 skipping mutations in lung cancer: Screening, functional and clinical impact von Fernandes, Marie, Jamme, Philippe, Paget, Sonia, Morabito, Angela, Leprêtre, Frédéric, Figeac, Martin, Descarpentries, Clotilde, Escande, Fabienne, Baldacci, Simon, Chotteau-Lelièvre, Anne, Grumolato, Luca, Copin, Marie-Christine, Kherrouche, Zoulika, Cortot, Alexis B., Tulasne, David

Volltext

Brief report : High MET overexpression does not predict the presence of MET exon 14 splice mutations in NSCLC : results from the IFCT Predict.amm study von Baldacci, Simon, Figeac, Martin, Antoine, Martine, Descarpentries, Clotilde, Kherrouche, Zoulika, Jamme, Philippe, Copin, Marie-Christine, Tulasne, David, Nanni, Isabelle, Beau-Faller, Michèle, Melaabi, Samia, Levallet, Guenaelle, Quoix, Elisabeth, Moro-Sibilot, Denis, Friard, Sylvie, Missy, Pascale, Barlesi, Fabrice, Cadranel, Jacques, Cortot, Alexis

Volltext

MA 07.06 Detection of Mechanisms of Resistance to ALK Inhibitors in Routine Practice: A Retrospective Study von Jamme, P., Descarpentries, C., Wislez, M., Dansin, E., Grégoire, V., Baldacci, S., Escande, F., Mathiot, N., Kyheng, M., Kherrouche, Z., Copin, M.C., Cortot, A.

Volltext

Spatial heterogeneity of KRAS mutations in colorectal cancers in northern France von Turpin, Anthony, Genin, Michael, Hebbar, Mohamed, Occelli, Florent, Lanier, Caroline, Vasseur, Francis, Descarpentries, Clotilde, Pannier, Diane, Ploquin, Anne

Volltext

BMET-31. DETECTION OF EGFR MUTATIONS IN THE CEREBRO-SPINAL FLUID OF NON-SMALL CELL LUNG CANCERS von Le Rhun, Emilie, Grégoire, Valérie, Girard, Edwina, Baranzelli, Anne, Baldacci, Simon, Descarpentries, Clotilde, Maurage, Claude Alain, Cortot, Alexis B, Escande, Fabienne

Volltext

Three Rounds of External Quality Assessment in France to Evaluate the Performance of 28 Platforms for Multiparametric Molecular Testing in Metastatic Colorectal and Non-Small Cell... von Dequeker, Elisabeth M.C, Keppens, Cleo, Egele, Caroline, Delen, Sofie, Lamy, Aude, Lemoine, Antoinette, Sabourin, Jean-Christophe, Andrieu, Catherine, Ligtenberg, Marjolijn, Fetique, Dominique, Tops, Bastiaan, Descarpentries, Clotilde, Blons, Hélène, Denoux, Yves, Aube, Cécile, Penault-Llorca, Frederique, Hofman, Paul, Leroy, Karen, Le Marechal, Cédric, Doucet, Laurent, Duranton-Tanneur, Valérie, Pedeutour, Florence, Soubeyran, Isabelle, Côté, Jean-François, Emile, Jean-François, Vignaud, Jean-Michel, Monhoven, Nathalie, Haddad, Véronique, Laurent-Puig, Pierre, van Krieken, Han, Nowak, Frederique, Lonchamp, Etienne, Bellocq, Jean-Pierre, Rouleau, Etienne

Volltext

Is Modification of Diet in Renal Disease Formula Similar to Cockcroft–Gault Formula to Assess Renal Function in Elderly Hospitalized Patients Treated With Low-Molecular-Weight Hepa... von Gouin-Thibault, Isabelle, Pautas, Eric, Mahé, Isabelle, Descarpentries, Clotilde, Nivet-Antoine, Valérie, Golmard, Jean-Louis, Siguret, Virginie

Volltext