The TAM family: phosphatidylserine-sensing receptor tyrosine kinases gone awry in cancer von Graham, Douglas K., DeRyckere, Deborah, Davies, Kurtis D., Earp, H. Shelton

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Molecular Pathways: MERTK Signaling in Cancer von CUMMINGS, Christopher T, DERYCKERE, Deborah, EARP, H. Shelton, GRAHAM, Douglas K

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The Emerging Role of TYRO3 as a Therapeutic Target in Cancer von Smart, Sherri K, Vasileiadi, Eleana, Wang, Xiaodong, DeRyckere, Deborah, Graham, Douglas K

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MERTK activation drives osimertinib resistance in EGFR-mutant non-small cell lung cancer von Yan, Dan, Huelse, Justus M, Kireev, Dmitri, Tan, Zikang, Chen, Luxiao, Goyal, Subir, Wang, Xiaodong, Frye, Stephen V, Behera, Madhusmita, Schneider, Frank, Ramalingam, Suresh S, Owonikoko, Taofeek, Earp, H Shelton, DeRyckere, Deborah, Graham, Douglas K

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Obesity-induced galectin-9 is a therapeutic target in B-cell acute lymphoblastic leukemia von Lee, Miyoung, Hamilton, Jamie A. G., Talekar, Ganesh R., Ross, Anthony J., Michael, Langston, Rupji, Manali, Dwivedi, Bhakti, Raikar, Sunil S., Boss, Jeremy, Scharer, Christopher D., Graham, Douglas K., DeRyckere, Deborah, Porter, Christopher C., Henry, Curtis J.

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Single-cell analysis reveals altered tumor microenvironments of relapse- and remission-associated pediatric acute myeloid leukemia von Mumme, Hope, Thomas, Beena E., Bhasin, Swati S., Krishnan, Upaasana, Dwivedi, Bhakti, Perumalla, Pruthvi, Sarkar, Debasree, Ulukaya, Gulay B., Sabnis, Himalee S., Park, Sunita I., DeRyckere, Deborah, Raikar, Sunil S., Pauly, Melinda, Summers, Ryan J., Castellino, Sharon M., Wechsler, Daniel S., Porter, Christopher C., Graham, Douglas K., Bhasin, Manoj

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Pediatric T-cell acute lymphoblastic leukemia blast signature and MRD associated immune environment changes defined by single cell transcriptomics analysis von Bhasin, Swati S., Thomas, Beena E., Summers, Ryan J., Sarkar, Debasree, Mumme, Hope, Pilcher, William, Emam, Mohamed, Raikar, Sunil S., Park, Sunita I., Castellino, Sharon M., Graham, Douglas K., Bhasin, Manoj K., DeRyckere, Deborah

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MERTK receptor tyrosine kinase is a therapeutic target in melanoma von Schlegel, Jennifer, Sambade, Maria J, Sather, Susan, Moschos, Stergios J, Tan, Aik-Choon, Winges, Amanda, DeRyckere, Deborah, Carson, Craig C, Trembath, Dimitri G, Tentler, John J, Eckhardt, S Gail, Kuan, Pei-Fen, Hamilton, Ronald L, Duncan, Lyn M, Miller, C Ryan, Nikolaishvili-Feinberg, Nana, Midkiff, Bentley R, Liu, Jing, Zhang, Weihe, Yang, Chao, Wang, Xiaodong, Frye, Stephen V, Earp, H Shelton, Shields, Janiel M, Graham, Douglas K

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Inhibition of MERTK Promotes Suppression of Tumor Growth in BRAF Mutant and BRAF Wild-Type Melanoma von Sinik, Lenka, Minson, Katherine A, Tentler, John J, Carrico, Jacqueline, Bagby, Stacey M, Robinson, William A, Kami, Rotem, Burstyn-Cohen, Tal, Eckhardt, S Gail, Wang, Xiaodong, Frye, Stephen V, Earp, H Shelton, DeRyckere, Deborah, Graham, Douglas K

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Small Molecule Inhibition of MERTK Is Efficacious in Non-Small Cell Lung Cancer Models Independent of Driver Oncogene Status von Cummings, Christopher T, Zhang, Weihe, Davies, Kurtis D, Kirkpatrick, Gregory D, Zhang, Dehui, DeRyckere, Deborah, Wang, Xiaodong, Frye, Stephen V, Earp, H Shelton, Graham, Douglas K

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Single-cell RNA sequencing distinctly characterizes the wide heterogeneity in pediatric mixed phenotype acute leukemia von Mumme, Hope L, Raikar, Sunil S, Bhasin, Swati S, Thomas, Beena E, Lawrence, Taylor, Weinzierl, Elizabeth P, Pang, Yakun, DeRyckere, Deborah, Gawad, Chuck, Wechsler, Daniel S, Porter, Christopher C, Castellino, Sharon M, Graham, Douglas K, Bhasin, Manoj

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MERTK Inhibition Induces Polyploidy and Promotes Cell Death and Cellular Senescence in Glioblastoma Multiforme von Sufit, Alexandra, Lee-Sherick, Alisa B, DeRyckere, Deborah, Rupji, Manali, Dwivedi, Bhakti, Varella-Garcia, Marileila, Pierce, Angela M, Kowalski, Jeanne, Wang, Xiaodong, Frye, Stephen V, Earp, H Shelton, Keating, Amy K, Graham, Douglas K

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Pseudo-Cyclization through Intramolecular Hydrogen Bond Enables Discovery of Pyridine Substituted Pyrimidines as New Mer Kinase Inhibitors von Zhang, Weihe, Zhang, Dehui, Stashko, Michael A, DeRyckere, Deborah, Hunter, Debra, Kireev, Dmitri, Miley, Michael J, Cummings, Christopher, Lee, Minjung, Norris-Drouin, Jacqueline, Stewart, Wendy M, Sather, Susan, Zhou, Yingqiu, Kirkpatrick, Gregory, Machius, Mischa, Janzen, William P, Earp, H. Shelton, Graham, Douglas K, Frye, Stephen V, Wang, Xiaodong

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Discovery of Macrocyclic Pyrimidines as MerTK‐Specific Inhibitors von McIver, Andrew L., Zhang, Weihe, Liu, Qingyang, Jiang, Xinpeng, Stashko, Michael A., Nichols, James, Miley, Michael J., Norris‐Drouin, Jacqueline, Machius, Mischa, DeRyckere, Deborah, Wood, Edgar, Graham, Douglas K., Earp, H. Shelton, Kireev, Dmitri, Frye, Stephen V., Wang, Xiaodong

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Targeting the TAM Receptors in Leukemia von Huey, Madeline G, Minson, Katherine A, Earp, H Shelton, DeRyckere, Deborah, Graham, Douglas K

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Risk-associated alterations in marrow T cells in pediatric leukemia von Bailur, Jithendra Kini, McCachren, Samuel S., Pendleton, Katherine, Vasquez, Juan C., Lim, Hong Seo, Duffy, Alyssa, Doxie, Deon B., Kaushal, Akhilesh, Foster, Connor, DeRyckere, Deborah, Castellino, Sharon, Kemp, Melissa L., Qiu, Peng, Dhodapkar, Madhav, Dhodapkar, Kavita M.

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Efficacy of a Mer and Flt3 tyrosine kinase small molecule inhibitor, UNC1666, in acute myeloid leukemia von Lee-Sherick, Alisa B, Zhang, Weihe, Menachof, Kelly K, Hill, Amanda A, Rinella, Sean, Kirkpatrick, Gregory, Page, Lauren S, Stashko, Michael A, Jordan, Craig T, Wei, Qi, Liu, Jing, Zhang, Dehui, DeRyckere, Deborah, Wang, Xiaodong, Frye, Stephen, Earp, H Shelton, Graham, Douglas K

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Association of race/ethnicity with innate immune tumor microenvironment of children with B-acute lymphoblastic leukemia von Gilbert, Julie R, Sabnis, Himalee S, Radzievski, Roman, Doxie, Deon B, DeRyckere, Deborah, Castellino, Sharon M, Dhodapkar, Kavita

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Prolonged exposure to a Mer ligand in leukemia: Gas6 favors expression of a partial Mer glycoform and reveals a novel role for Mer in the nucleus von Migdall-Wilson, Justine, Bates, Christine, Schlegel, Jennifer, Brandão, Luis, Linger, Rachel M A, DeRyckere, Deborah, Graham, Douglas K

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Discovery of Small Molecule Mer Kinase Inhibitors for the Treatment of Pediatric Acute Lymphoblastic Leukemia von Liu, Jing, Yang, Chao, Simpson, Catherine, DeRyckere, Deborah, Van Deusen, Amy, Miley, Michael J, Kireev, Dmitri, Norris-Drouin, Jacqueline, Sather, Susan, Hunter, Debra, Korboukh, Victoria K, Patel, Hari S, Janzen, William P, Machius, Mischa, Johnson, Gary L, Earp, H. Shelton, Graham, Douglas K, Frye, Stephen V, Wang, Xiaodong

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