Pyridylpiperazine-based allosteric inhibitors of RND-type multidrug efflux pumps von Plé, Coline, Tam, Heng-Keat, Vieira Da Cruz, Anais, Compagne, Nina, Jiménez-Castellanos, Juan-Carlos, Müller, Reinke T., Pradel, Elizabeth, Foong, Wuen Ee, Malloci, Giuliano, Ballée, Alexia, Kirchner, Moritz A., Moshfegh, Parisa, Herledan, Adrien, Herrmann, Andrea, Deprez, Benoit, Willand, Nicolas, Vargiu, Attilio Vittorio, Pos, Klaas M., Flipo, Marion, Hartkoorn, Ruben C.

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Efficient propylphosphonic anhydride (®T3P) mediated synthesis of benzothiazoles, benzoxazoles and benzimidazoles von Wen, Xiaoan, Bakali, Jamal El, Deprez-Poulain, Rebecca, Deprez, Benoit

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Optimization of 1,2,4-Triazole-3-thiones toward Broad-Spectrum Metallo-β-lactamase Inhibitors Showing Potent Synergistic Activity on VIM- and NDM-1-Producing Clinical Isolates von Legru, Alice, Verdirosa, Federica, Vo-Hoang, Yen, Tassone, Giusy, Vascon, Filippo, Thomas, Caitlyn A., Sannio, Filomena, Corsica, Giuseppina, Benvenuti, Manuela, Feller, Georges, Coulon, Rémi, Marcoccia, Francesca, Devente, Savannah Rowane, Bouajila, Ezeddine, Piveteau, Catherine, Leroux, Florence, Deprez-Poulain, Rebecca, Deprez, Benoît, Licznar-Fajardo, Patricia, Crowder, Michael W., Cendron, Laura, Pozzi, Cecilia, Mangani, Stefano, Docquier, Jean-Denis, Hernandez, Jean-François, Gavara, Laurent

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The Bile Acid Chenodeoxycholic Acid Increases Human Brown Adipose Tissue Activity von Broeders, Evie P.M., Nascimento, Emmani B.M., Havekes, Bas, Brans, Boudewijn, Roumans, Kay H.M., Tailleux, Anne, Schaart, Gert, Kouach, Mostafa, Charton, Julie, Deprez, Benoit, Bouvy, Nicole D., Mottaghy, Felix, Staels, Bart, van Marken Lichtenbelt, Wouter D., Schrauwen, Patrick

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Catalytic site inhibition of insulin-degrading enzyme by a small molecule induces glucose intolerance in mice von Deprez-Poulain, Rebecca, Hennuyer, Nathalie, Bosc, Damien, Liang, Wenguang G., Enée, Emmanuelle, Marechal, Xavier, Charton, Julie, Totobenazara, Jane, Berte, Gonzague, Jahklal, Jouda, Verdelet, Tristan, Dumont, Julie, Dassonneville, Sandrine, Woitrain, Eloise, Gauriot, Marion, Paquet, Charlotte, Duplan, Isabelle, Hermant, Paul, Cantrelle, François- Xavier, Sevin, Emmanuel, Culot, Maxime, Landry, Valerie, Herledan, Adrien, Piveteau, Catherine, Lippens, Guy, Leroux, Florence, Tang, Wei-Jen, van Endert, Peter, Staels, Bart, Deprez, Benoit

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Rescue of nonsense mutations by amlexanox in human cells von Gonzalez-Hilarion, Sara, Beghyn, Terence, Jia, Jieshuang, Debreuck, Nadège, Berte, Gonzague, Mamchaoui, Kamel, Mouly, Vincent, Gruenert, Dieter C, Déprez, Benoit, Lejeune, Fabrice

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Insulin‐degrading enzyme inhibition increases the unfolded protein response and favours lipid accumulation in the liver von Andres, Marine, Hennuyer, Nathalie, Zibar, Khamis, Bicharel‐Leconte, Marie, Duplan, Isabelle, Enée, Emmanuelle, Vallez, Emmanuelle, Herledan, Adrien, Loyens, Anne, Staels, Bart, Deprez, Benoit, Endert, Peter, Deprez‐Poulain, Rebecca, Lancel, Steve

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Combination therapy for tuberculosis treatment: pulmonary administration of ethionamide and booster co-loaded nanoparticles von Costa-Gouveia, Joana, Pancani, Elisabetta, Jouny, Samuel, Machelart, Arnaud, Delorme, Vincent, Salzano, Giuseppina, Iantomasi, Raffaella, Piveteau, Catherine, Queval, Christophe J., Song, Ok-Ryul, Flipo, Marion, Deprez, Benoit, Saint-André, Jean-Paul, Hureaux, José, Majlessi, Laleh, Willand, Nicolas, Baulard, Alain, Brodin, Priscille, Gref, Ruxandra

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Ensemble cryoEM elucidates the mechanism of insulin capture and degradation by human insulin degrading enzyme von Zhang, Zhening, Liang, Wenguang G, Bailey, Lucas J, Tan, Yong Zi, Wei, Hui, Wang, Andrew, Farcasanu, Mara, Woods, Virgil A, McCord, Lauren A, Lee, David, Shang, Weifeng, Deprez-Poulain, Rebecca, Deprez, Benoit, Liu, David R, Koide, Akiko, Koide, Shohei, Kossiakoff, Anthony A, Li, Sheng, Carragher, Bridget, Potter, Clinton S, Tang, Wei-Jen

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NMR Spectroscopy of the Main Protease of SARS‐CoV‐2 and Fragment‐Based Screening Identify Three Protein Hotspots and an Antiviral Fragment von Cantrelle, François‐Xavier, Boll, Emmanuelle, Brier, Lucile, Moschidi, Danai, Belouzard, Sandrine, Landry, Valérie, Leroux, Florence, Dewitte, Frédérique, Landrieu, Isabelle, Dubuisson, Jean, Deprez, Benoit, Charton, Julie, Hanoulle, Xavier

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Controlling Plasma Stability of Hydroxamic Acids: A MedChem Toolbox von Hermant, Paul, Bosc, Damien, Piveteau, Catherine, Gealageas, Ronan, Lam, BaoVy, Ronco, Cyril, Roignant, Matthieu, Tolojanahary, Hasina, Jean, Ludovic, Renard, Pierre-Yves, Lemdani, Mohamed, Bourotte, Marilyne, Herledan, Adrien, Bedart, Corentin, Biela, Alexandre, Leroux, Florence, Deprez, Benoit, Deprez-Poulain, Rebecca

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Design and synthesis of water-soluble prodrugs of rifabutin for intraveneous administration von Antraygues, Kevin, Maingot, Mathieu, Schellhorn, Birgit, Trebosc, Vincent, Gitzinger, Marc, Deprez, Benoit, Defert, Olivier, Dale, Glenn E., Bourotte, Marilyne, Lociuro, Sergio, Willand, Nicolas

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Drug repurposing and phenotypic screening: innovative strategies for treating ultra-rare disorders von Paquot, Adrien, Deprez, Benoit, Beghyn, Terence

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Reversion of antibiotic resistance in Mycobacterium tuberculosis by spiroisoxazoline SMARt-420 von Blondiaux, Nicolas, Moune, Martin, Desroses, Matthieu, Frita, Rosangela, Flipo, Marion, Mathys, Vanessa, Soetaert, Karine, Kiass, Mehdi, Delorme, Vincent, Djaout, Kamel, Trebosc, Vincent, Kemmer, Christian, Wintjens, René, Wohlkönig, Alexandre, Antoine, Rudy, Huot, Ludovic, Hot, David, Coscolla, Mireia, Feldmann, Julia, Gagneux, Sebastien, Locht, Camille, Brodin, Priscille, Gitzinger, Marc, Déprez, Benoit, Willand, Nicolas, Baulard, Alain R.

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Molecular Design in Practice: A Review of Selected Projects in a French Research Institute That Illustrates the Link between Chemical Biology and Medicinal Chemistry von Deprez, Benoit, Bosc, Damien, Charton, Julie, Couturier, Cyril, Deprez-Poulain, Rebecca, Flipo, Marion, Leroux, Florence, Villemagne, Baptiste, Willand, Nicolas

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Modulators of hERAP2 discovered by high-throughput screening von Medve, Laura, Gealageas, Ronan, Lam, Bao Vy, Guillaume, Valentin, Castillo-Aguilera, Omar, Camberlein, Virgyl, Piveteau, Catherine, Rosell, Melissa, Fleau, Charlotte, Warenghem, Sandrine, Charton, Julie, Dumont-Ryckembusch, Julie, Bosc, Damien, Leroux, Florence, van Endert, Peter, Deprez, Benoit, Deprez-Poulain, Rebecca

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Tuberculosis: The drug development pipeline at a glance von Villemagne, Baptiste, Crauste, Céline, Flipo, Marion, Baulard, Alain R., Déprez, Benoit, Willand, Nicolas

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Kinetic target-guided synthesis in drug discovery and chemical biology: a comprehensive facts and figures survey von Bosc, Damien, Jakhlal, Jouda, Deprez, Benoit, Deprez-Poulain, Rebecca

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Friedländer synthesis of polysubstituted quinolines and naphthyridines promoted by propylphosphonic anhydride (T3P®) under mild conditions von Jida, Mouhamad, Deprez, Benoit

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Insulin-Degrading Enzyme, an Under-Estimated Potential Target to Treat Cancer? von Lesire, Laetitia, Leroux, Florence, Deprez-Poulain, Rebecca, Deprez, Benoit

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