Differential expression of CCR8 in tumors versus normal tissue allows specific depletion of tumor-infiltrating T regulatory cells by GS-1811, a novel Fc-optimized anti-CCR8 antibod... von Weaver, Jessica D., Stack, Edward C., Buggé, Joshua A., Hu, Changyun, McGrath, Lara, Mueller, Amy, Wong, Masie, Klebanov, Boris, Rahman, Tanzila, Kaufman, Rosemary, Fregeau, Christine, Spaulding, Vikki, Priess, Michelle, Legendre, Kristen, Jaffe, Sarah, Upadhyay, Dhruvkumar, Singh, Anirudh, Xu, Chang-Ai, Krukenberg, Kristin, Zhang, Yan, Ezzyat, Yassine, Saddier Axe, Dorothée, Kuhne, Michelle R., Meehl, Michael A., Shaffer, Donald R., Weist, Brian M., Wiederschain, Dmitri, Depis, Fabien, Gostissa, Monica

Volltext

Unstable FoxP3⁺ T regulatory cells in NZW mice von Dépis, Fabien, Kwon, Ho-Keun, Mathis, Diane, Benoist, Christophe

Volltext

T Regulatory Cells Support Plasma Cell Populations in the Bone Marrow von Glatman Zaretsky, Arielle, Konradt, Christoph, Dépis, Fabien, Wing, James B., Goenka, Radhika, Atria, Daniela Gomez, Silver, Jonathan S., Cho, Sunglim, Wolf, Amaya I., Quinn, William J., Engiles, Julie B., Brown, Dorothy C., Beiting, Daniel, Erikson, Jan, Allman, David, Cancro, Michael P., Sakaguchi, Shimon, Lu, Li-Fan, Benoist, Christophe O., Hunter, Christopher A.

Volltext

Stable Expression of FOXP3 and Core Tolerogenic Genes by Engineered Human Tregs von Zarin, Payam, Sassone-Corsi, Martina, Doherty, Abigail, Chicoine, Adam, DeVault, Victoria, Li, Xiang, Yam, Jennifer, Wickham, Thomas, Chen, Tiffany, Depis, Fabien

Volltext

Selective Antibody Intervention of Toll-like Receptor 4 Activation through Fc γ Receptor Tethering von Shang, Limin, Daubeuf, Bruno, Triantafilou, Martha, Olden, Robin, Dépis, Fabien, Raby, Anne-Catherine, Herren, Suzanne, Dos Santos, Anaelle, Malinge, Pauline, Dunn-Siegrist, Irene, Benmkaddem, Sanae, Geinoz, Antoine, Magistrelli, Giovanni, Rousseau, François, Buatois, Vanessa, Salgado-Pires, Susana, Reith, Walter, Monteiro, Renato, Pugin, Jérôme, Leger, Olivier, Ferlin, Walter, Kosco-Vilbois, Marie, Triantafilou, Kathy, Elson, Greg

Volltext

Combination therapies in the context of anti-CD3 antibodies for the treatment of autoimmune diseases von Dean, Yann, Dépis, Fabien, Kosco-Vilbois, Marie

Volltext

Pivotal Involvement of Fcγ Receptor IIA in the Neutralization of Lipopolysaccharide Signaling via a Potent Novel Anti-TLR4 Monoclonal Antibody 15C1 von Dunn-Siegrist, Irene, Leger, Olivier, Daubeuf, Bruno, Poitevin, Yves, Dépis, Fabien, Herren, Suzanne, Kosco-Vilbois, Marie, Dean, Yann, Pugin, Jérôme, Elson, Greg

Volltext

Long-term amelioration of established collagen-induced arthritis achieved with short-term therapy combining anti-CD3 and anti-tumor necrosis factor treatments von Dépis, Fabien, Hatterer, Eric, Lamacchia, Céline, Waldburger, Jean-Marc, Gabay, Cem, Reith, Walter, Kosco-Vilbois, Marie, Dean, Yann

Volltext

Characterization of a surrogate murine antibody to model anti-human CD3 therapies von Dépis, Fabien, Hatterer, Eric, Ballet, Romain, Daubeuf, Bruno, Cons, Laura, Glatt, Sophie, Reith, Walter, Kosco-Vilbois, Marie, Dean, Yann

Volltext

COMBINATION THERAPIES AND METHODS USING ANTI-CD3 MODULATING AGENTS AND ANTI-IL-6 ANTAGONISTS von DEAN, Yann, DEPIS, Fabien

Volltext bestellen

ENGINEERED REPAIR REGULATORY T CELLS von WICKHAM, Tom, ZARIN, Payam, KIEFFER-KWON, Philippe, DEPIS, Fabien

Volltext bestellen

Abstract 4532: Preclinical evaluation of JTX-1811, an anti-CCR8 antibody with enhanced ADCC activity, for preferential depletion of tumor-infiltrating regulatory T cells von Dépis, Fabien, Hu, Changyun, Weaver, Jessica, McGrath, Lara, Klebanov, Boris, Buggé, Joshua, Umiker, Ben, Fregeau, Christine, Upadhyay, Dhruvkumar, Singh, Anirudh, Xu, Chang-Ai, Spaulding, Vikki, Priess, Michelle, Wong, Masie, Naheed, Seema, Zhang, Yan, Legendre, Kristin, Stack, Edward C., Mora, Alessandro, Willer, Margaret, Meetze, Kristan, Gostissa, Monica, Meehl, Michael A., Shaffer, Donald R.

Volltext

Combination Therapies and Methods Using Anti-CD3 Modulating Agents and Anti-IL-6 Antagonists von DEPIS FABIEN, DEAN YANN

Volltext bestellen

ANTIBODIES AND FUSION PROTEINS THAT BIND TO CCR8 AND USES THEREOF von DEPIS, FABIEN, PRESTA, LEONARD G, MCGRATH, LARA LEWIS, HU, CHANGYUN, BUGGE, JOSHUA ADAM

Volltext bestellen

COMBINATION THERAPIES AND METHODS USING ANTI-CD3 MODULATING AGENTS AND ANTI-IL-6 ANTAGONISTS von DEAN, YANN, DEPIS, FABIEN

Volltext bestellen

Combination Therapies and Methods Using Anti-CD3 Modulating Agents and Anti-IL-6 Antagonists von DEPIS FABIEN, DEAN YANN

Volltext bestellen

ANTI-TNFR2 ANTIBODIES AND USES THEREOF von KURELLA, Vinodh B, TANG, Jian, TAM, Eric M, MUDA, Marco, FULTON, Ross Bane, DUGAST, Anne-Sophie, DRUMMOND, Daryl Clark, RAUE, Klaus Andreas, DEPIS, Fabien, KUMAR, Sandeep

Volltext bestellen

Antibodies and fusion proteins that bind to CCR8 and uses thereof von DEPIS, FABIEN, PRESTA, LEONARD G, MCGRATH, LARA LEWIS, HU, CHANG-YUN, BUGGE, JOSHUA ADAM

Volltext bestellen

ANTIBODIES AND FUSION PROTEINS THAT BIND TO CCR8, AND USES THEREOF von JOSHUA ADAM BUGGE, FABIEN DEPIS, LARA LEWIS MCGRATH, LEONARD G PRESTA, HU CHANGYUN

Volltext bestellen

ANTI-TNFR2 ANTIBODIES AND USES THEREOF von RAUE, Klaus, Andreas, KURELLA, Vinodh, B, FULTON, Ross, Bane, TANG, Jian, TAM, Eric, M, MUDA, Marco, DUGAST, Anne-sophie, DRUMMOND, Daryl, Clark, DEPIS, Fabien, KUMAR, Sandeep

Volltext bestellen