Targeting Transcription Factors for Cancer Treatment von Lambert, Mélanie, Jambon, Samy, Depauw, Sabine, David-Cordonnier, Marie-Hélène

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Defective germinal center selection results in persistence of self-reactive B cells from the primary to the secondary repertoire in Primary Antiphospholipid Syndrome von Dieudonné, Yannick, Lorenzetti, Raquel, Rottura, Julien, Janowska, Iga, Frenger, Quentin, Jacquel, Léa, Vollmer, Olivier, Carbone, Francesco, Chengsong, Zhu, Luka, Marine, Depauw, Sabine, Wadier, Nadège, Giorgiutti, Stéphane, Nespola, Benoît, Herb, Agathe, Voll, Reinhard Edmund, Guffroy, Aurélien, Poindron, Vincent, Ménager, Mickaël, Martin, Thierry, Soulas-Sprauel, Pauline, Rizzi, Marta, Korganow, Anne-Sophie, Gies, Vincent

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Heterocyclic Diamidine DNA Ligands as HOXA9 Transcription Factor Inhibitors: Design, Molecular Evaluation, and Cellular Consequences in a HOXA9-Dependant Leukemia Cell Model von Depauw, Sabine, Lambert, Mélanie, Jambon, Samy, Paul, Ananya, Peixoto, Paul, Nhili, Raja, Marongiu, Laura, Figeac, Martin, Dassi, Christelle, Paul-Constant, Charles, Billoré, Benjamin, Kumar, Arvind, Farahat, Abdelbasset A, Ismail, Mohamed A, Mineva, Ekaterina, Sweat, Daniel P, Stephens, Chad E, Boykin, David W, Wilson, W. David, David-Cordonnier, Marie-Hélène

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Targeting the DNA-binding activity of the human ERG transcription factor using new heterocyclic dithiophene diamidines von Nhili, Raja, Peixoto, Paul, Depauw, Sabine, Flajollet, Sébastien, Dezitter, Xavier, Munde, Manoj M, Ismail, Mohamed A, Kumar, Arvind, Farahat, Abdelbasset A, Stephens, Chad E, Duterque-Coquillaud, Martine, David Wilson, W, Boykin, David W, David-Cordonnier, Marie-Hélène

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Novel Substituted Benzothiophene and Thienothiophene Carboxanilides and Quinolones: Synthesis, Photochemical Synthesis, DNA-Binding Properties, Antitumor Evaluation and 3D-Derived... von Aleksić, Maja, Bertoša, Branimir, Nhili, Raja, Uzelac, Lidija, Jarak, Ivana, Depauw, Sabine, David-Cordonnier, Marie-Hélène, Kralj, Marijeta, Tomić, Sanja, Karminski-Zamola, Grace

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Induction of AML cell differentiation using HOXA9/DNA binding inhibitors as a potential therapeutic option for HOXA9‐dependent AML von Lambert, Mélanie, Jambon, Samy, Bouhlel, Mohamed A., Depauw, Sabine, Vrevin, Julie, Blanck, Samuel, Marot, Guillemette, Figeac, Martin, Preudhomme, Claude, Quesnel, Bruno, Boykin, David W., David‐Cordonnier, Marie‐Hélène

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Protein Recognition in Drug-Induced DNA Alkylation: When the Moonlight Protein GAPDH Meets S23906-1/DNA Minor Groove Adducts von Savreux-Lenglet, Gaëlle, Depauw, Sabine, David-Cordonnier, Marie-Hélène

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Photochemical electrocyclisation of 3-vinylindoles to pyrido[2,3- a]-, pyrido[4,3- a]- and thieno[2,3- a]-carbazoles: Design, synthesis, DNA binding and antitumor cell cytotoxicity von Lemster, Thomas, Pindur, Ulf, Lenglet, Gaelle, Depauw, Sabine, Dassi, Christelle, David-Cordonnier, Marie-Hélène

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Influence of the Stereoisomeric Position of the Reactive Acetate Groups of the Benzo[b]Acronycine derivative S23906-1 on Its DNA Alkylation, Helix-Opening, Cytotoxic, and Antitumor... von Sabine Depauw, Thomas Gaslonde, Stéphane Léonce, Laurence Kraus-Berthier, William Laine, Gaëlle Lenglet, Angèle Chiaroni, Bruno Pfeiffer, Christian Bailly, Sylvie Michel, François Tillequin, Alain PierrÃ, Marie-Hélène David-Cordonnier

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Direct and Indirect Targeting of HOXA9 Transcription Factor in Acute Myeloid Leukemia von Lambert, Mélanie, Alioui, Meryem, Jambon, Samy, Depauw, Sabine, Van Seuningen, Isabelle, David-Cordonnier, Marie-Hélène

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Novel amidino substituted benzimidazole and benzothiazole benzo[b]thieno-2-carboxamides exert strong antiproliferative and DNA binding properties von Cindrić, Maja, Jambon, Samy, Harej, Anja, Depauw, Sabine, David-Cordonnier, Marie-Hélène, Kraljević Pavelić, Sandra, Karminski-Zamola, Grace, Hranjec, Marijana

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Loss of function of XBP1 splicing activity of IRE1α favors B cell tolerance breakdown von Reuschlé, Quentin, Van Heddegem, Laurien, Bosteels, Victor, Moncan, Matthieu, Depauw, Sabine, Wadier, Nadège, Maréchal, Sandra, De Nolf, Clint, Delgado, Virginia, Messai, Yosra, Stolzenberg, Marie-Claude, Magérus, Aude, Werck, Angélique, Olagne, Jérôme, Li, Quan, Lefevre, Guillaume, Korganow, Anne-Sophie, Rieux-Laucat, Frédéric, Janssens, Sophie, Soulas-Sprauel, Pauline

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Synthesis, antitumor activity and DNA binding features of benzothiazolyl and benzimidazolyl substituted isoindolines von Sović, Irena, Jambon, Samy, Kraljević Pavelić, Sandra, Markova-Car, Elitza, Ilić, Nataša, Depauw, Sabine, David-Cordonnier, Marie-Hélène, Karminski-Zamola, Grace

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Direct and Indirect Targeting of HOXA9 Transcription Factor in Acute Myeloid Leukemia von Lambert, Mélanie, Alioui, M, Jambon, Samy, Depauw, Sabine, Seuningen, Isabelle Van, David-Cordonnier, Marie-Hélène

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Protein recognition of the S23906-1-DNA adduct by nuclear proteins: direct involvement of glyceraldehyde-3-phosphate dehydrogenase (GAPDH) von Lenglet, Gaëlle, Depauw, Sabine, Mendy, Denise, David-Cordonnier, Marie-Hélène

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Water-Mediated Binding of Agents that Target the DNA Minor Groove von Liu, Yang, Kumar, Arvind, Depauw, Sabine, Nhili, Raja, David-Cordonnier, Marie-Hélène, Lee, Michael P, Ismail, Mohamed A, Farahat, Abdelbasset A, Say, Martial, Chackal-Catoen, Sarah, Batista-Parra, Adalgisa, Neidle, Stephen, Boykin, David W, Wilson, W. David

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Synthesis, Antitumor Activity, and Mechanism of Action of Benzo[b]chromeno[6,5‑g][1,8]naphthyridin-7-one Analogs of Acronycine von Tian, Wen, Yougnia, Rodrigue, Depauw, Sabine, Lansiaux, Amélie, David-Cordonnier, Marie-Hélène, Pfeiffer, Bruno, Kraus-Berthier, Laurence, Léonce, Stéphane, Pierré, Alain, Dufat, Hanh, Michel, Sylvie

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Novel phenyl and pyridyl substituted derivatives of isoindolines: Synthesis, antitumor activity and DNA binding features von Sović, Irena, Kraljević Pavelić, Sandra, Markova-Car, Elitza, Ilić, Nataša, Nhili, Raja, Depauw, Sabine, David-Cordonnier, Marie-Hélène, Karminski-Zamola, Grace

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Anilides and quinolones with nitrogen-bearing substituents from benzothiophene and thienothiophene series: Synthesis, photochemical synthesis, cytostatic evaluation, 3D-derived QSA... von Aleksić, Maja, Bertoša, Branimir, Nhili, Raja, Depauw, Sabine, Martin-Kleiner, Irena, David-Cordonnier, Marie-Hélène, Tomić, Sanja, Kralj, Marijeta, Karminski-Zamola, Grace

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Mixed up minor groove binders: Convincing A·T specific compounds to recognize a G·C base pair von Paul, Ananya, Nanjunda, Rupesh, Kumar, Arvind, Laughlin, Sarah, Nhili, Raja, Depauw, Sabine, Deuser, Shelby Sheldon, Chai, Yun, Chaudhary, Arpana S., David-Cordonnier, Marie-Hélène, Boykin, David W., Wilson, W. David

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