Synthesis and bioevaluation of 22-hydroxyacuminatine analogs von Grillet, François, Baumlová, Barbora, Prévost, Grégoire, Constant, Jean-François, Chaumeron, Sophie, Bigg, Dennis C.H., Greene, Andrew E., Kanazawa, Alice

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Homocamptothecins:  Synthesis and Antitumor Activity of Novel E-Ring-Modified Camptothecin Analogues von Lavergne, Olivier, Lesueur-Ginot, Laurence, Pla Rodas, Francesc, Kasprzyk, Philip G, Pommier, Jacques, Demarquay, Danièle, Prévost, Grégoire, Ulibarri, Gérard, Rolland, Alain, Schiano-Liberatore, Anne-Marie, Harnett, Jeremiah, Pons, Dominique, Camara, José, Bigg, Dennis C. H

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IRC‐083864, a novel bis quinone inhibitor of CDC25 phosphatases active against human cancer cells von Brezak, Marie‐Christine, Valette, Annie, Quaranta, Muriel, Contour‐Galcera, Marie‐Odile, Jullien, Denis, Lavergne, Olivier, Frongia, Céline, Bigg, Dennis, Kasprzyk, Philip G., Prevost, Grégoire Pierre, Ducommun, Bernard

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BN80927: A novel homocamptothecin that inhibits proliferation of human tumor cells in vitro and in vivo von DEMARQUAY, Danièle, HUCHET, Marion, COULOMB, Helène, LESUEUR-GINOT, Laurence, LAVERGNE, Olivier, CAMARA, José, KASPRZYK, Philip G, PREVOST, Grégoire, BIGG, Dennis C. H

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Topoisomerase I-Mediated Antiproliferative Activity of Enantiomerically Pure Fluorinated Homocamptothecins von Lavergne, Olivier, Demarquay, Danièle, Bailly, Christian, Lanco, Christophe, Rolland, Alain, Huchet, Marion, Coulomb, Helène, Muller, Nicole, Baroggi, Nicole, Camara, José, Le Breton, Christine, Manginot, Eric, Cazaux, Jean-Bernard, Bigg, Dennis C. H

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Homocamptothecin, an E-Ring-Modified Camptothecin Analogue, Generates New Topoisomerase I-Mediated DNA Breaks von Bailly, Christian, Lansiaux, Amélie, Dassonneville, Laurent, Demarquay, Danièle, Coulomb, Hélène, Huchet, Marion, Lavergne, Olivier, Bigg, Dennis C. H

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IRC-083927 is a new tubulin binder that inhibits growth of human tumor cells resistant to standard tubulin-binding agents von Liberatore, Anne-Marie, Coulomb, Hélène, Pons, Dominique, Dutruel, Olivier, Kasprzyk, Philip G, Carlson, Mark, Nelson, Ann Savola, Newman, Simon P, Stengel, Chloe, Auvray, Pierrïck, Hesry, Vincent, Foll, Béatrice, Narboux, Nadine, Morlais, Delphine, Le Moing, Mélissa, Bernetiere, Sonia, Dellile, Raphael, Camara, Jose, Ferrandis, Eric, Bigg, Dennis C, Prévost, Grégoire P

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BN 80933, a Dual Inhibitor of Neuronal Nitric Oxide Synthase and Lipid Peroxidation: A Promising Neuroprotective Strategy von Chabrier, Pierre-Etienne, Auguet, Michel, Spinnewyn, Brigitte, Auvin, Serge, Cornet, Sylvie, Demerle-Pallardy, Caroline, Guilmard-Favre, Christine, Marin, Jean-Gregoire, Pignol, Bernadette, Gillard-Roubert, Veronique, Roussillot-Charnet, Christelle, Schulz, Jocelyne, Viossat, Isabelle, Bigg, Dennis, Moncada, Salvador

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New Method of Synthesis of Vinca Alkaloid Derivatives von Fahy, Jacques, Thillaye du Boullay, Valérie, Bigg, Dennis C.H

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Unusual potency of BN 80915, a novel fluorinated E-ring modified camptothecin, toward human colon carcinoma cells von LARSEN, Annette K, GILBERT, Cristèle, CHYZAK, Ginette, PLISOV, Sergey Y, NAGUIBNEVA, Irina, LAVERGNE, Olivier, LESUEUR-GINOT, Laurence, BIGG, Dennis C. H

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Aluminum Chloride-Promoted Transamidation Reactions von Bon, Eric, Bigg, Dennis C. H, Bertrand, Guy

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What's new on CDC25 phosphatase inhibitors von Contour-Galcera, Marie-Odile, Sidhu, Alban, Prévost, Grégoire, Bigg, Dennis, Ducommun, Bernard

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Novel azoles as potent and selective cannabinoid CB2 receptor agonists von Harnett, Jeremiah J., Dolo, Christine, Viossat, Isabelle, Auger, Florence, Ferrandis, Eric, Bigg, Dennis, Auguet, Michel, Auvin, Serge, Chabrier, Pierre-E.

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Apoptosis Induced by the Homocamptothecin Anticancer Drug BN80915 in HL-60 Cells von Lansiaux, A, Facompré, M, Wattez, N, Hildebrand, M P, Bal, C, Demarquay, D, Lavergne, O, Bigg, D C, Bailly, C

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Homocamptothecin, an E-Ring-modified Camptothecin, Exerts More Potent Antiproliferative Activity than Other Topoisomerase I Inhibitors in Human Colon Cancers Obtained from Surgery... von PHILIPPART, P, HARPER, L, MENDES DA COSTA, P, KISS, R, CHABOTEAUX, C, DECAESTECKER, C, BRONCKART, Y, GORDOVER, L, LESUEUR-GINOT, L, MALONNE, H, LAVERGNE, O, BIGG, D. C. H

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Aluminum Chloride-Promoted Aminolysis of N-Tosyl Lactams von Bon, Eric, Biggs, Dennis C. H, Bertrand, Guy, Bigg, Dennis C. H

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Activation of Imidazolides Using Methyl Trifluoromethanesulfonate: A Convenient Method for the Preparation of Hindered Esters and Amides von Ulibarri, Gerardo, Choret, Nadège, Bigg, Dennis C. H.

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Aluminum trichloride-promoted aminolysis of cyclic imides and oxazolidinones von Bon, Eric, Réau, Régis, Bertrand, Guy, Bigg, Dennis C.H

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Homocamptothecin, an E-ring modified camptothecin with enhanced lactone stability, retains topoisomerase I-targeted activity and antitumor properties von LESUEUR-GINOT, L, DEMARQUAY, D, KISS, R, KASPRZYK, P. G, DASSONNEVILLE, L, BAILLY, C, CAMARA, J, LAVERGNE, O, BIGG, D. C. H

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Novel [2-(4-Piperidinyl)ethyl](thio)ureas: synthesis and antiacetylcholinesterase activity von Vidaluc, Jean-Louis, Calmel, Francis, Bigg, Dennis, Carilla, Elisabeth, Stenger, Antoine, Chopin, Philippe, Briley, Mike

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