Identification of Atuveciclib (BAY 1143572), the First Highly Selective, Clinical PTEFb/CDK9 Inhibitor for the Treatment of Cancer von Lücking, Ulrich, Scholz, Arne, Lienau, Philip, Siemeister, Gerhard, Kosemund, Dirk, Bohlmann, Rolf, Briem, Hans, Terebesi, Ildiko, Meyer, Kirstin, Prelle, Katja, Denner, Karsten, Bömer, Ulf, Schäfer, Martina, Eis, Knut, Valencia, Ray, Ince, Stuart, von Nussbaum, Franz, Mumberg, Dominik, Ziegelbauer, Karl, Klebl, Bert, Choidas, Axel, Nussbaumer, Peter, Baumann, Matthias, Schultz‐Fademrecht, Carsten, Rühter, Gerd, Eickhoff, Jan, Brands, Michael

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Drug–Drug Interaction Potential of Darolutamide: In Vitro and Clinical Studies von Zurth, Christian, Koskinen, Mikko, Fricke, Robert, Prien, Olaf, Korjamo, Timo, Graudenz, Kristina, Denner, Karsten, Bairlein, Michaela, von Bühler, Clemens-Jeremias, Wilkinson, Gary, Gieschen, Hille

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Effects of non-ionic surfactants on cytochrome P450-mediated metabolism in vitro von Christiansen, Anne, Backensfeld, Thomas, Denner, Karsten, Weitschies, Werner

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Changing for the Better: Discovery of the Highly Potent and Selective CDK9 Inhibitor VIP152 Suitable for Once Weekly Intravenous Dosing for the Treatment of Cancer von Lücking, Ulrich, Kosemund, Dirk, Böhnke, Niels, Lienau, Philip, Siemeister, Gerhard, Denner, Karsten, Bohlmann, Rolf, Briem, Hans, Terebesi, Ildiko, Bömer, Ulf, Schäfer, Martina, Ince, Stuart, Mumberg, Dominik, Scholz, Arne, Izumi, Raquel, Hwang, Stuart, von Nussbaum, Franz

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The protein-tyrosine phosphatase DEP-1 modulates growth factor-stimulated cell migration and cell-matrix adhesion von Jandt, Enrico, Denner, Karsten, Kovalenko, Marina, Östman, Arne, Böhmer, Frank-D

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Damage Incorporated: Discovery of the Potent, Highly Selective, Orally Available ATR Inhibitor BAY 1895344 with Favorable Pharmacokinetic Properties and Promising Efficacy in Monot... von Lücking, Ulrich, Wortmann, Lars, Wengner, Antje M, Lefranc, Julien, Lienau, Philip, Briem, Hans, Siemeister, Gerhard, Bömer, Ulf, Denner, Karsten, Schäfer, Martina, Koppitz, Marcus, Eis, Knut, Bartels, Florian, Bader, Benjamin, Bone, Wilhelm, Moosmayer, Dieter, Holton, Simon J, Eberspächer, Uwe, Grudzinska-Goebel, Joanna, Schatz, Christoph, Deeg, Gesa, Mumberg, Dominik, von Nussbaum, Franz

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Drug-drug interaction (DDI) of darolutamide with cytochrome P450 (CYP) and P-glycoprotein (P-gp) substrates: Results from clinical and in vitro studies von Zurth, Christian, Graudenz, Kristina, Denner, Karsten, Korjamo, Timo, Fricke, Robert, Wilkinson, Gary, Seitz, Friedeborg, Prien, Olaf

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Discovery of IRAK4 Inhibitors BAY1834845 (Zabedosertib) and BAY1830839 von Bothe, Ulrich, Günther, Judith, Nubbemeyer, Reinhard, Siebeneicher, Holger, Ring, Sven, Bömer, Ulf, Peters, Michaele, Rausch, Alexandra, Denner, Karsten, Himmel, Herbert, Sutter, Andreas, Terebesi, Ildiko, Lange, Martin, Wengner, Antje M., Guimond, Nicolas, Thaler, Tobias, Platzek, Johannes, Eberspächer, Uwe, Schäfer, Martina, Steuber, Holger, Zollner, Thomas M., Steinmeyer, Andreas, Schmidt, Nicole

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Mass Balance and Metabolic Pathways of Eliapixant, a P2X3 Receptor Antagonist, in Healthy Male Volunteers von Reif, Stefanie, Schultze-Mosgau, Marcus-Hillert, Engelen, Anna, Piel, Isabel, Denner, Karsten, Roffel, Ad, Tiessen, Renger, Klein, Stefan, Francke, Klaus, Rottmann, Antje

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Discovery of BAY 2666605, a Molecular Glue for PDE3A and SLFN12 von Lewis, Timothy A., Ellermann, Manuel, Kopitz, Charlotte, Lange, Martin, de Waal, Luc, Wu, Xiaoyun, Tersteegen, Adrian, Denner, Karsten, Lienau, Philip, Kaulfuss, Stefan, Goldoni, Silvia, Meyerson, Matthew, Greulich, Heidi, Gradl, Stefan N.

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Metabolism and Mass Balance of the Novel Nonsteroidal Androgen Receptor Inhibitor Darolutamide in Humans von Taavitsainen, Päivi, Prien, Olaf, Kähkönen, Marja, Niehues, Michael, Korjamo, Timo, Denner, Karsten, Nykänen, Pirjo, Vuorela, Annamari, Jungmann, Natalia A., von Bühler, Clemens-Jeremias, Koskinen, Mikko, Zurth, Christian, Gieschen, Hille

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Drug–Drug Interaction Potential of Darolutamide: In Vitro and Clinical Studies von Zurth, Christian, Koskinen, Mikko, Fricke, Robert, Prien, Olaf, Korjamo, Timo, Graudenz, Kristina, Denner, Karsten, Bairlein, Michaela, Clemens-Jeremias Von Bühler, Wilkinson, Gary, Gieschen, Hille

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Site-selective Dephosphorylation of the Platelet-derived Growth Factor β-Receptor by the Receptor-like Protein-tyrosine Phosphatase DEP-1 von Kovalenko, Marina, Denner, Karsten, Sandström, Jill, Persson, Camilla, Groβ, Steffen, Jandt, Enrico, Vilella, Ramon, Böhmer, Frank, Östman, Arne

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Functional Characterization of Atherosclerosis-Associated Ser128Arg and Leu554Phe E-Selectin Mutations von Wenzel, K., Stahn, R., Speer, A., Denner, K., Gläser, C., Affeldt, M., Moobed, M., Scheer, A., Baumann, G., Felix, S.B.

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Cloning of CYP11B1 and CYP11B2 from normal human adrenal and their functional expression in COS-7 and V79 chinese hamster cells von Denner, Karsten, Doehmer, Johannes, Bernhardt, Rita

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Conferring aldosterone synthesis to human CYP11B1 by replacing key amino acid residues with CYP11B2‐specific ones von Böttner, Benjamin, Denner, Karsten, Bernhardt, Rita

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Site-selective Dephosphorylation of the Platelet-derived Growth Factor β-Receptor by the Receptor-like Protein-tyrosine Phosphatase DEP-1 von Marina Kovalenko, Karsten Denner, Jill Sandström, Camilla Persson, Steffen GroÎ, Enrico Jandt, Ramon Vilella, Frank Böhmer, Arne Östman

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Demineralized Bone Matrix-stimulated Bone Regeneration in Rats Enhanced by an Angiogenic Dipeptide Derivate von Hansen, A, Pruss, A, Gollnick, K, Bochentin, B, Denner, K, Von Versen, R

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Carrier-mediated residual K+ and Na+ transport of human red blood cells von DENNER, K, HEINRICH, R, BERNHARDT, I

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DIAMINOHETEROARYL SUBSTITUTED INDAZOLES von HITCHCOCK Marion, FERNANDEZ-MONTALVAN Amaury Ernesto, BRIEM Hans, SCHRÖDER Jens, HILGER Christoph-Stephan, SIEMEISTER Gerhard, HOLTON Simon, PREUßE Cornelia, DENNER Karsten

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