Contribution of amino acids in the active site of dipeptidyl peptidase 4 to the catalytic action of the enzyme von Gnoth, Kathrin, Bär, Joachim Wolfgang, Rosche, Fred, Rahfeld, Jens-Ulrich, Demuth, Hans-Ulrich

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Amyloid-Beta Peptides Trigger Aggregation of Alpha-Synuclein In Vitro von Koeppen, Janett, Schulze, Anja, Machner, Lisa, Wermann, Michael, Eichentopf, Rico, Guthardt, Max, Haehnel, Angelika, Klehm, Jessica, Kriegeskorte, Marie-Christin, Hartlage-Ruebsamen, Maike, Morawski, Markus, von Hoersten, Stephan, Demuth, Hans-Ulrich, Rossner, Steffen, Schilling, Stephan

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N-Terminal pyroglutamate formation of Aβ38 and Aβ40 enforces oligomer formation and potency to disrupt hippocampal long-term potentiation von Schlenzig, Dagmar, Rönicke, Raik, Cynis, Holger, Ludwig, Hans-Henning, Scheel, Eike, Reymann, Klaus, Saido, Takaomi, Hause, Gerd, Schilling, Stephan, Demuth, Hans-Ulrich

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Posttranslational modification impact on the mechanism by which amyloid‐β induces synaptic dysfunction von Grochowska, Katarzyna M, Yuanxiang, PingAn, Bär, Julia, Raman, Rajeev, Brugal, Gemma, Sahu, Giriraj, Schweizer, Michaela, Bikbaev, Arthur, Schilling, Stephan, Demuth, Hans‐Ulrich, Kreutz, Michael R

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Natural Products from Microalgae with Potential against Alzheimer's Disease: Sulfolipids Are Potent Glutaminyl Cyclase Inhibitors von Hielscher-Michael, Stephanie, Griehl, Carola, Buchholz, Mirko, Demuth, Hans-Ulrich, Arnold, Norbert, Wessjohann, Ludger A

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Pyroglutamate Formation Influences Solubility and Amyloidogenicity of Amyloid Peptides von Schlenzig, Dagmar, Manhart, Susanne, Cinar, Yeliz, Kleinschmidt, Martin, Hause, Gerd, Willbold, Dieter, Funke, Susanne Aileen, Schilling, Stephan, Demuth, Hans-Ulrich

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Kallikrein‐related peptidases are activators of the CC chemokine CCL14 von Grünberg, Mario, Quandt, Dagmar, Cynis, Holger, Demuth, Hans‐Ulrich, Kindermann, Andrea, Magdolen, Viktor, Forssmann, Wolf‐Georg, Seliger, Barbara, Mägert, Hans‐Jürgen

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QUINT: Workflow for Quantification and Spatial Analysis of Features in Histological Images From Rodent Brain von Yates, Sharon C, Groeneboom, Nicolaas E, Coello, Christopher, Lichtenthaler, Stefan F, Kuhn, Peer-Hendrik, Demuth, Hans-Ulrich, Hartlage-Rübsamen, Maike, Roßner, Steffen, Leergaard, Trygve, Kreshuk, Anna, Puchades, Maja A, Bjaalie, Jan G

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Crystal structure of the incretin-bound extracellular domain of a G protein-coupled receptor von Parthier, Christoph, Kleinschmidt, Martin, Neumann, Piotr, Rudolph, Rainer, Manhart, Susanne, Schlenzig, Dagmar, Fanghänel, Jörg, Rahfeld, Jens-Ulrich, Demuth, Hans-Ulrich, Stubbs, Milton T

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Enhanced Fibril Fragmentation of N-Terminally Truncated and Pyroglutamyl-Modified Aβ Peptides von Wulff, Melanie, Baumann, Monika, Thümmler, Anka, Yadav, Jay K., Heinrich, Liesa, Knüpfer, Uwe, Schlenzig, Dagmar, Schierhorn, Angelika, Rahfeld, Jens-Ulrich, Horn, Uwe, Balbach, Jochen, Demuth, Hans-Ulrich, Fändrich, Marcus

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Structure and Dynamics of Meprin β in Complex with a Hydroxamate-Based Inhibitor von Linnert, Miriam, Fritz, Claudia, Jaeger, Christian, Schlenzig, Dagmar, Ramsbeck, Daniel, Kleinschmidt, Martin, Wermann, Michael, Demuth, Hans-Ulrich, Parthier, Christoph, Schilling, Stephan

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Glutaminyl cyclases from animals and plants: a case of functionally convergent protein evolution von Schilling, Stephan, Wasternack, Claus, Demuth, Hans-Ulrich

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N-terminal pyroglutamate formation in CX3CL1 is essential for its full biologic activity von Kehlen, Astrid, Haegele, Monique, Böhme, Livia, Cynis, Holger, Hoffmann, Torsten, Demuth, Hans-Ulrich

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Purification and Characterization of Recombinant N-Terminally Pyroglutamate-Modified Amyloid-β Variants and Structural Analysis by Solution NMR Spectroscopy von Dammers, Christina, Gremer, Lothar, Neudecker, Philipp, Demuth, Hans-Ulrich, Schwarten, Melanie, Willbold, Dieter

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Structural Analysis and Aggregation Propensity of Pyroglutamate Aβ(3-40) in Aqueous Trifluoroethanol von Dammers, Christina, Gremer, Lothar, Reiß, Kerstin, Klein, Antonia N, Neudecker, Philipp, Hartmann, Rudolf, Sun, Na, Demuth, Hans-Ulrich, Schwarten, Melanie, Willbold, Dieter

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A novel human tau knock-in mouse model reveals interaction of Abeta and human tau under progressing cerebral amyloidosis in 5xFAD mice von Barendrecht, Susan, Schreurs, An, Geissler, Stefanie, Sabanov, Victor, Ilse, Victoria, Rieckmann, Vera, Eichentopf, Rico, Künemund, Anja, Hietel, Benjamin, Wussow, Sebastian, Hoffmann, Katrin, Körber-Ferl, Kerstin, Pandey, Ravi, Carter, Gregory W, Demuth, Hans-Ulrich, Holzer, Max, Roßner, Steffen, Schilling, Stephan, Preuss, Christoph, Balschun, Detlef, Cynis, Holger

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The isoenzyme of glutaminyl cyclase is an important regulator of monocyte infiltration under inflammatory conditions von Cynis, Holger, Hoffmann, Torsten, Friedrich, Daniel, Kehlen, Astrid, Gans, Kathrin, Kleinschmidt, Martin, Rahfeld, Jens‐Ulrich, Wolf, Raik, Wermann, Michael, Stephan, Anett, Haegele, Monique, Sedlmeier, Reinhard, Graubner, Sigrid, Jagla, Wolfgang, Müller, Anke, Eichentopf, Rico, Heiser, Ulrich, Seifert, Franziska, Quax, Paul H. A., de Vries, Margreet R., Hesse, Isabel, Trautwein, Daniela, Wollert, Ulrich, Berg, Sabine, Freyse, Ernst‐Joachim, Schilling, Stephan, Demuth, Hans‐Ulrich

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Neuropeptide Y (NPY) in cerebrospinal fluid from patients with Huntington's Disease: increased NPY levels and differential degradation of the NPY1–30 fragment von Wagner, Leona, Björkqvist, Maria, Lundh, Sofia Hult, Wolf, Raik, Börgel, Arne, Schlenzig, Dagmar, Ludwig, Hans‐Henning, Rahfeld, Jens‐Ulrich, Leavitt, Blair, Demuth, Hans‐Ulrich, Petersén, Åsa, Hörsten, Stephan

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The Crystal Structure of Dipeptidyl Peptidase IV (CD26) Reveals Its Functional Regulation and Enzymatic Mechanism von Engel, Michael, Hoffmann, Torsten, Wagner, Leona, Wermann, Michael, Heiser, Ulrich, Kiefersauer, Reiner, Huber, Robert, Bode, Wolfram, Demuth, Hans-Ulrich, Brandstetter, Hans

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Immunohistochemical Evidence from APP-Transgenic Mice for Glutaminyl Cyclase as Drug Target to Diminish pE-Abeta Formation von Hartlage-Rübsamen, Maike, Bluhm, Alexandra, Piechotta, Anke, Linnert, Miriam, Rahfeld, Jens-Ulrich, Demuth, Hans-Ulrich, Lues, Inge, Kuhn, Peer-Hendrik, Lichtenthaler, Stefan F, Roßner, Steffen, Höfling, Corinna

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