Metagenomics of Parkinson’s disease implicates the gut microbiome in multiple disease mechanisms von Wallen, Zachary D., Demirkan, Ayse, Twa, Guy, Cohen, Gwendolyn, Dean, Marissa N., Standaert, David G., Sampson, Timothy R., Payami, Haydeh

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Genome-wide association study identifies novel genetic variants contributing to variation in blood metabolite levels von Draisma, Harmen H. M., Pool, René, Kobl, Michael, Jansen, Rick, Petersen, Ann-Kristin, Vaarhorst, Anika A. M., Yet, Idil, Haller, Toomas, Demirkan, Ayşe, Esko, Tõnu, Zhu, Gu, Böhringer, Stefan, Beekman, Marian, van Klinken, Jan Bert, Römisch-Margl, Werner, Prehn, Cornelia, Adamski, Jerzy, de Craen, Anton J. M., van Leeuwen, Elisabeth M., Amin, Najaf, Dharuri, Harish, Westra, Harm-Jan, Franke, Lude, de Geus, Eco J. C., Hottenga, Jouke Jan, Willemsen, Gonneke, Henders, Anjali K., Montgomery, Grant W., Nyholt, Dale R., Whitfield, John B., Penninx, Brenda W., Spector, Tim D., Metspalu, Andres, Eline Slagboom, P., van Dijk, Ko Willems, ‘t Hoen, Peter A. C., Strauch, Konstantin, Martin, Nicholas G., van Ommen, Gert-Jan B., Illig, Thomas, Bell, Jordana T., Mangino, Massimo, Suhre, Karsten, McCarthy, Mark I., Gieger, Christian, Isaacs, Aaron, van Duijn, Cornelia M., Boomsma, Dorret I.

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Integration of epidemiologic, pharmacologic, genetic and gut microbiome data in a drug–metabolite atlas von Liu, Jun, Lahousse, Lies, Nivard, Michel G., Bot, Mariska, Chen, Lianmin, van Klinken, Jan Bert, Thesing, Carisha S., Beekman, Marian, van den Akker, Erik Ben, Slieker, Roderick C., Waterham, Eveline, van der Kallen, Carla J. H., de Boer, Irene, Li-Gao, Ruifang, Vojinovic, Dina, Amin, Najaf, Radjabzadeh, Djawad, Kraaij, Robert, Alferink, Louise J. M., Murad, Sarwa Darwish, Uitterlinden, André G., Willemsen, Gonneke, Pool, Rene, Milaneschi, Yuri, van Heemst, Diana, Suchiman, H. Eka D., Rutters, Femke, Elders, Petra J. M., Beulens, Joline W. J., van der Heijden, Amber A. W. A., van Greevenbroek, Marleen M. J., Arts, Ilja C. W., Onderwater, Gerrit L. J., van den Maagdenberg, Arn M. J. M., Mook-Kanamori, Dennis O., Hankemeier, Thomas, Terwindt, Gisela M., Stehouwer, Coen D. A., Geleijnse, Johanna M., ‘t Hart, Leen M., Slagboom, P. Eline, van Dijk, Ko Willems, Zhernakova, Alexandra, Fu, Jingyuan, Penninx, Brenda W. J. H., Boomsma, Dorret I., Demirkan, Ayşe, Stricker, Bruno H. C., van Duijn, Cornelia M.

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The Neuronal Transporter Gene SLC6A15 Confers Risk to Major Depression von Kohli, Martin A., Lucae, Susanne, Saemann, Philipp G., Schmidt, Mathias V., Demirkan, Ayse, Hek, Karin, Czamara, Darina, Alexander, Michael, Salyakina, Daria, Ripke, Stephan, Hoehn, David, Specht, Michael, Menke, Andreas, Hennings, Johannes, Heck, Angela, Wolf, Christiane, Ising, Marcus, Schreiber, Stefan, Czisch, Michael, Müller, Marianne B., Uhr, Manfred, Bettecken, Thomas, Becker, Albert, Schramm, Johannes, Rietschel, Marcella, Maier, Wolfgang, Bradley, Bekh, Ressler, Kerry J., Nöthen, Markus M., Cichon, Sven, Craig, Ian W., Breen, Gerome, Lewis, Cathryn M., Hofman, Albert, Tiemeier, Henning, van Duijn, Cornelia M., Holsboer, Florian, Müller-Myhsok, Bertram, Binder, Elisabeth B.

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Large-scale whole-exome sequencing association studies identify rare functional variants influencing serum urate levels von Tin, Adrienne, Li, Yong, Brody, Jennifer A., Nutile, Teresa, Chu, Audrey Y., Huffman, Jennifer E., Yang, Qiong, Chen, Ming-Huei, Robinson-Cohen, Cassianne, Macé, Aurélien, Liu, Jun, Demirkan, Ayşe, Sorice, Rossella, Sedaghat, Sanaz, Swen, Melody, Yu, Bing, Ghasemi, Sahar, Teumer, Alexanda, Vollenweider, Peter, Ciullo, Marina, Li, Meng, Uitterlinden, André G., Kraaij, Robert, Amin, Najaf, van Rooij, Jeroen, Kutalik, Zoltán, Dehghan, Abbas, McKnight, Barbara, van Duijn, Cornelia M., Morrison, Alanna, Psaty, Bruce M., Boerwinkle, Eric, Fox, Caroline S., Woodward, Owen M., Köttgen, Anna

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Bile Microbiome Signatures Associated with Pancreatic Ductal Adenocarcinoma Compared to Benign Disease: A UK Pilot Study von Merali, Nabeel, Chouari, Tarak, Terroire, Julien, Jessel, Maria-Danae, Liu, Daniel S K, Smith, James-Halle, Wooldridge, Tyler, Dhillon, Tony, Jiménez, José I, Krell, Jonathan, Roberts, Keith J, Rockall, Timothy A, Velliou, Eirini, Sivakumar, Shivan, Giovannetti, Elisa, Demirkan, Ayse, Annels, Nicola E, Frampton, Adam E

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CDH6 and HAGH protein levels in plasma associate with Alzheimer’s disease in APOE ε4 carriers von Ahmad, Shahzad, Milan, Marta del Campo, Hansson, Oskar, Demirkan, Ayse, Agustin, Ruiz, Sáez, Maria E., Giagtzoglou, Nikolaos, Cabrera-Socorro, Alfredo, Bakker, Margot H. M., Ramirez, Alfredo, Hankemeier, Thomas, Stomrud, Erik, Mattsson-Carlgren, Niklas, Scheltens, Philip, van der Flier, Wiesje M., Ikram, M. Arfan, Malarstig, Anders, Teunissen, Charlotte E., Amin, Najaf, van Duijn, Cornelia M.

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Adipose Tissue Gene Expression of Adiponectin, Tumor Necrosis Factor-α and Leptin in Metabolic Syndrome Patients with Coronary Artery Disease von Gormez, Selcuk, Demirkan, Ayse, Atalar, Fatmahan, Caynak, Baris, Erdim, Refik, Sozer, Volkan, Gunay, Demet, Akpinar, Bellhan, Ozbek, Ugur, Buyukdevrim, Ahmet Sevim

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A novel method for serum lipoprotein profiling using high performance capillary isotachophoresis von Moreno-Gordaliza, Estefanía, van der Lee, Sven J., Demirkan, Ayşe, van Duijn, Cornelia M., Kuiper, Johan, Lindenburg, Petrus W., Hankemeier, Thomas

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Tumor necrosis factor α, interleukin-6 and interleukin-10 polymorphisms in preeclampsia von Vural, Pervin, Degirmencioglu, Sevgin, Saral, Neslihan Y., Demirkan, Ayse, Akgul, Cemil, Yildirim, Gokhan, Issever, Halim, Eroglu, Hacer

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Presence of fatty-acid-binding protein 4 expression in human epicardial adipose tissue in metabolic syndrome von Vural, Burcak, Atalar, Fatmahan, Ciftci, Cavlan, Demirkan, Ayse, Susleyici-Duman, Belgin, Gunay, Demet, Akpinar, Belhhan, Sagbas, Ertan, Ozbek, Ugur, Buyukdevrim, Ahmet Sevim

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A Mendelian Randomization Study of Metabolite Profiles, Fasting Glucose, and Type 2 Diabetes von Liu, Jun, van Klinken, Jan Bert, Semiz, Sabina, van Dijk, Ko Willems, Verhoeven, Aswin, Hankemeier, Thomas, Harms, Amy C, Sijbrands, Eric, Sheehan, Nuala A, van Duijn, Cornelia M, Demirkan, Ayşe

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A multi-omics study of circulating phospholipid markers of blood pressure von Liu, Jun, de Vries, Paul S., Del Greco M., Fabiola, Johansson, Åsa, Schraut, Katharina E., Hayward, Caroline, van Dijk, Ko Willems, Franco, Oscar. H., Hicks, Andrew A., Vitart, Veronique, Rudan, Igor, Campbell, Harry, Polašek, Ozren, Pramstaller, Peter P., Wilson, James F., Gyllensten, Ulf, van Duijn, Cornelia M., Dehghan, Abbas, Demirkan, Ayşe

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Lipidomic profiling identifies signatures of metabolic risk von Yin, Xiaoyan, Willinger, Christine M., Keefe, Joshua, Liu, Jun, Fernández-Ortiz, Antonio, Ibáñez, Borja, Peñalvo, José, Adourian, Aram, Chen, George, Corella, Dolores, Pamplona, Reinald, Portero-Otin, Manuel, Jove, Mariona, Courchesne, Paul, van Duijn, Cornelia M., Fuster, Valentín, Ordovás, José M., Demirkan, Ayşe, Larson, Martin G., Levy, Daniel

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Insight in genome-wide association of metabolite quantitative traits by exome sequence analyses von Demirkan, Ayşe, Henneman, Peter, Verhoeven, Aswin, Dharuri, Harish, Amin, Najaf, van Klinken, Jan Bert, Karssen, Lennart C, de Vries, Boukje, Meissner, Axel, Göraler, Sibel, van den Maagdenberg, Arn M J M, Deelder, André M, C 't Hoen, Peter A, van Duijn, Cornelia M, van Dijk, Ko Willems

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Metabolomics based markers predict type 2 diabetes in a 14-year follow-up study von Liu, Jun, Semiz, Sabina, van der Lee, Sven J., van der Spek, Ashley, Verhoeven, Aswin, van Klinken, Jan B., Sijbrands, Eric, Harms, Amy C., Hankemeier, Thomas, van Dijk, Ko Willems, van Duijn, Cornelia M., Demirkan, Ayşe

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comorbidPGS: An R Package Assessing Shared Predisposition between Phenotypes Using Polygenic Scores von Pascat, Vincent, Zudina, Liudmila, Ulrich, Anna, Maina, Jared G., Kaakinen, Marika, Pupko, Igor, Bonnefond, Amélie, Demirkan, Ayse, Balkhiyarova, Zhanna, Froguel, Philippe, Prokopenko, Inga

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Plasma phosphatidylcholine and sphingomyelin concentrations are associated with depression and anxiety symptoms in a Dutch family-based lipidomics study von Demirkan, Ayşe, Isaacs, Aaron, Ugocsai, Peter, Liebisch, Gerhard, Struchalin, Maksim, Rudan, Igor, Wilson, James F, Pramstaller, Peter P, Gyllensten, Ulf, Campbell, Harry, Schmitz, Gerd, Oostra, Ben A, van Duijn, Cornelia M

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Metabolic profiling of intra- and extracranial carotid artery atherosclerosis von Vojinovic, Dina, van der Lee, Sven J., van Duijn, Cornelia M., Vernooij, Meike W., Kavousi, Maryam, Amin, Najaf, Demirkan, Ayşe, Ikram, M. Arfan, van der Lugt, Aad, Bos, Daniel

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Bile Microbiome Signatures as Biomarkers for Differentiating Pancreatic Ductal Adenocarcinoma from Benign Disease: Discovery of novel microbial signatures in a UK pilot study von Merali, Nabeel, Terroire, Julien, Jessel, Maria Danae, Demirkan, Ayse, Annells, Nicola, Frampton, Adam

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