Whole-exome sequencing and high throughput genotyping identified KCNJ11 as the thirteenth MODY gene von Bonnefond, Amélie, Philippe, Julien, Durand, Emmanuelle, Dechaume, Aurélie, Huyvaert, Marlène, Montagne, Louise, Marre, Michel, Balkau, Beverley, Fajardy, Isabelle, Vambergue, Anne, Vatin, Vincent, Delplanque, Jérôme, Le Guilcher, David, De Graeve, Franck, Lecoeur, Cécile, Sand, Olivier, Vaxillaire, Martine, Froguel, Philippe

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A Genome-Wide Scan for Childhood Obesity–Associated Traits in French Families Shows Significant Linkage on Chromosome 6q22.31-q23.2 von MEYRE, David, LECOEUR, Cécile, DELPLANQUE, Jérome, FRANCKE, Stephan, VATIN, Vincent, DURAND, Emmanuelle, WEILL, Jacques, DINA, Christian, FROGUEL, Philippe

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Molecular diagnosis of neonatal diabetes mellitus using next-generation sequencing of the whole exome von Bonnefond, Amélie, Durand, Emmanuelle, Sand, Olivier, De Graeve, Franck, Gallina, Sophie, Busiah, Kanetee, Lobbens, Stéphane, Simon, Albane, Bellanné-Chantelot, Christine, Létourneau, Louis, Scharfmann, Raphael, Delplanque, Jérôme, Sladek, Robert, Polak, Michel, Vaxillaire, Martine, Froguel, Philippe

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Post genome-wide association studies of novel genes associated with type 2 diabetes show gene-gene interaction and high predictive value von Cauchi, Stéphane, Meyre, David, Durand, Emmanuelle, Proença, Christine, Marre, Michel, Hadjadj, Samy, Choquet, Hélène, De Graeve, Franck, Gaget, Stefan, Allegaert, Frederic, Delplanque, Jérôme, Permutt, Marshall Alan, Wasson, Jon, Blech, Ilana, Charpentier, Guillaume, Balkau, Beverley, Vergnaud, Anne-Claire, Czernichow, Sébastien, Patsch, Wolfgang, Chikri, Mohamed, Glaser, Benjamin, Sladek, Robert, Froguel, Philippe

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Two new Loci for body-weight regulation identified in a joint analysis of genome-wide association studies for early-onset extreme obesity in French and german study groups von Scherag, André, Dina, Christian, Hinney, Anke, Vatin, Vincent, Scherag, Susann, Vogel, Carla I G, Müller, Timo D, Grallert, Harald, Wichmann, H-Erich, Balkau, Beverley, Heude, Barbara, Jarvelin, Marjo-Riitta, Hartikainen, Anna-Liisa, Levy-Marchal, Claire, Weill, Jacques, Delplanque, Jérôme, Körner, Antje, Kiess, Wieland, Kovacs, Peter, Rayner, Nigel W, Prokopenko, Inga, McCarthy, Mark I, Schäfer, Helmut, Jarick, Ivonne, Boeing, Heiner, Fisher, Eva, Reinehr, Thomas, Heinrich, Joachim, Rzehak, Peter, Berdel, Dietrich, Borte, Michael, Biebermann, Heike, Krude, Heiko, Rosskopf, Dieter, Rimmbach, Christian, Rief, Winfried, Fromme, Tobias, Klingenspor, Martin, Schürmann, Annette, Schulz, Nadja, Nöthen, Markus M, Mühleisen, Thomas W, Erbel, Raimund, Jöckel, Karl-Heinz, Moebus, Susanne, Boes, Tanja, Illig, Thomas, Froguel, Philippe, Hebebrand, Johannes, Meyre, David

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TMEM240 mutations cause spinocerebellar ataxia 21 with mental retardation and severe cognitive impairment von DELPLANQUE, Jérôme, DEVOS, David, BUEE, Luc, DESTEE, Alain, GROLEZ, Guillaume, DELMAIRE, Christine, DUJARDIN, Kathy, DELLACHERIE, Delphine, BRICE, Alexis, STEVANIN, Giovanni, STRUBI-VUILLAUME, Isabelle, DÜRR, Alexandra, HUIN, Vincent, SABLONNIERE, Bernard, GENET, Alexandre, SAND, Olivier, MOREAU, Caroline, GOIZET, Cyril, CHARLES, Perrine, ANHEIM, Mathieu, MONIN, Marie Lorraine

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Common Variants in FTO, MC4R, TMEM18, PRL, AIF1, and PCSK1 Show Evidence of Association With Adult Obesity in the Greek Population von Rouskas, Konstantinos, Kouvatsi, Anastasia, Paletas, Konstantinos, Papazoglou, Dimitrios, Tsapas, Apostolos, Lobbens, Stéphane, Vatin, Vincent, Durand, Emmanuelle, Labrune, Yann, Delplanque, Jérôme, Meyre, David, Froguel, Philippe

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Genome-wide association study for early-onset and morbid adult obesity identifies three new risk loci in European populations von Froguel, Philippe, Lobbens, Stéphane, Elliott, Paul, Sladek, Rob, Levy-Marchal, Claire, Balkau, Beverley, Polychronakos, Constantin, Gallina, Sophie, Proença, Christine, Meyre, David, Vatin, Vincent, Delplanque, Jérôme, Potoczna, Natascha, Kovacs, Peter, Tauber, Maithé, Järvelin, Marjo-Riitta, Marre, Michel, Weill, Jacques, Walley, Andrew, Degraeve, Franck, Horber, Fritz, Hercberg, Serge, Tichet, Jean, Coin, Lachlan J M, Dina, Christian, Körner, Antje, Lecoeur, Cécile, Hartikainen, Anna-Liisa, Asher, Julian, McCarthy, Mark I, Montpetit, Alexandre, Gaget, Stefan, Durand, Emmanuelle, Balding, David, Heude, Barbara, Blakemore, Alexandra I F, Kiess, Wieland, Pattou, François, Chèvre, Jean-Claude, Visvikis-Siest, Sophie

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A variant near MTNR1B is associated with increased fasting plasma glucose levels and type 2 diabetes risk von Chèvre, Jean-Claude, Pedersen, Oluf, Walley, Andrew J, Elliott, Paul, Sparsø, Thomas, Marre, Michel, Charpentier, Guillaume, Rocheleau, Ghislain, Pattou, François, Blakemore, Alexandra I F, Jarvelin, Marjo-Riita, Vaxillaire, Martine, Heude, Barbara, Bouatia-Naji, Nabila, Balkau, Beverley, Hartikainen, Anna-Liisa, De Graeve, Franck, Dina, Christian, Lobbens, Stéphane, Borch-Johnsen, Knut, Weill, Jacques, Schuit, Frans, Ruokonen, Aimo, Tauber, Maithé, Sladek, Robert, Delplanque, Jérôme, Cavalcanti-Proença, Christine, Meyre, David, Holmkvist, Johan, Hadjadj, Samy, Jørgensen, Torben, Durand, Emmanuelle, Marchand, Marion, Lévy-Marchal, Claire, Bonnefond, Amélie, Cauchi, Stéphane, Visvikis-Siest, Sophie, Hansen, Torben, Froguel, Philippe, Tichet, Jean, Lemaire, Katleen

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Tissue Distribution and Evolution of Fructosamine 3-Kinase and Fructosamine 3-Kinase-related Protein von Delplanque, Jérôme, Delpierre, Ghislain, Opperdoes, Fred R, Van Schaftingen, Emile

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Variation in FTO contributes to childhood obesity and severe adult obesity von Balkau, Beverley, Marre, Michel, Lecoeur, Cecile, Jacobson, Peter, Gallina, Sophie, Meyre, David, Vatin, Vincent, Ruiz, Juan, Froguel, Philippe, Potoczna, Natascha, Carlsson, Lena M S, Dina, Christian, Körner, Antje, Levy-Marchal, Claire, Cauchi, Stéphane, Vaillant, Emmanuel, Hercberg, Serge, Le Stunff, Catherine, Durand, Emmanuelle, Weill, Jacques, Horber, Fritz, Delplanque, Jérome, Kiess, Wieland, Kovacs, Peter, Chèvre, Jean-Claude, Bougnères, Pierre, Pattou, François

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The gene MAPK8IP1 , encoding islet-brain-1, is a candidate for type 2 diabetes von H Hani, El, Delplanque, Jérôme, Dina, Christian, Waeber, Gérard, Vionnet, Nathalie, Mooser, Vincent, Widmann, Christian, Nicod, Pascal, Bonny, Christophe, Miklossy, Judith, Froguel, Philippe, Maillard, Anne, Steinmann, Myriam, Boutin, Philippe

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R125W coding variant in TBC1D1 confers risk for familial obesity and contributes to linkage on chromosome 4p14 in the French population von Meyre, David, Farge, Morgane, Lecoeur, Cécile, Proenca, Christine, Durand, Emmanuelle, Allegaert, Frédéric, Tichet, Jean, Marre, Michel, Balkau, Beverley, Weill, Jacques, Delplanque, Jérôme, Froguel, Philippe

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Monoallelic pathogenic variants in LEPR do not cause obesity von Delplanque, Jérôme, Le Collen, Lauriane, Loiselle, Hélène, Leloire, Audrey, Toussaint, Bénédicte, Vaillant, Emmanuel, Charpentier, Guillaume, Franc, Sylvia, Balkau, Beverley, Marre, Michel, Henriques, Emma, Buse Falay, Emmanuel, Derhourhi, Mehdi, Froguel, Philippe, Bonnefond, Amélie

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Evaluating the Association of FAAH Common Gene Variation with Childhood, Adult Severe Obesity and Type 2 Diabetes in the French Population von Durand, Emmanuelle, Lecoeur, Cécile, Delplanque, Jérôme, Benzinou, Michael, Degraeve, Franck, Boutin, Philippe, Marre, Michel, Balkau, Beverley, Charpentier, Guillaume, Froguel, Philippe, Meyre, David

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Genome-wide association scans identified CTNNBL1 as a novel gene for obesity von Liu, Yong-Jun, Liu, Xiao-Gang, Wang, Liang, Dina, Christian, Yan, Han, Liu, Jian-Feng, Levy, Shawn, Papasian, Christopher J., Drees, Betty M., Hamilton, James J., Meyre, David, Delplanque, Jerome, Pei, Yu-Fang, Zhang, Lei, Recker, Robert R., Froguel, Philippe, Deng, Hong-Wen

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Type 2 Diabetes Whole-Genome Association Study in Four Populations: The DiaGen Consortium von Salonen, Jukka T., Uimari, Pekka, Aalto, Juha-Matti, Pirskanen, Mia, Kaikkonen, Jari, Todorova, Boryana, Hyppönen, Jelena, Korhonen, Veli-Pekka, Asikainen, Janne, Devine, Christopher, Tuomainen, Tomi-Pekka, Luedemann, Jan, Nauck, Matthias, Kerner, Wolfgang, Stephens, Richard H., New, John P., Ollier, William E., Gibson, J. Martin, Payton, Antony, Horan, Michael A., Pendleton, Neil, Mahoney, Walt, Meyre, David, Delplanque, Jerôme, Froguel, Philippe, Luzzatto, Oren, Yakir, Benjamin, Darvasi, Ariel

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Endocannabinoid receptor 1 gene variations increase risk for obesity and modulate body mass index in European populations von Benzinou, Michael, Chèvre, Jean-Claude, Ward, Kirsten J., Lecoeur, Cécile, Dina, Christian, Lobbens, Stephane, Durand, Emmanuelle, Delplanque, Jérome, Horber, Fritz F., Heude, Barbara, Balkau, Beverley, Borch-Johnsen, Knut, Jørgensen, Torben, Hansen, Torben, Pedersen, Oluf, Meyre, David, Froguel, Philippe

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Tryptophan metabolism activation by indoleamine 2,3-dioxygenase in adipose tissue of obese women: an attempt to maintain immune homeostasis and vascular tone von Wolowczuk, Isabelle, Hennart, Benjamin, Leloire, Audrey, Bessede, Alban, Soichot, Marion, Taront, Solenne, Caiazzo, Robert, Raverdy, Violeta, Pigeyre, Marie, Guillemin, Gilles J, Allorge, Delphine, Pattou, François, Froguel, Philippe, Poulain-Godefroy, Odile

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Genome-wide association for abdominal subcutaneous and visceral adipose reveals a novel locus for visceral fat in women von Fox, Caroline S, Liu, Yongmei, White, Charles C, Feitosa, Mary, Smith, Albert V, Heard-Costa, Nancy, Lohman, Kurt, Johnson, Andrew D, Foster, Meredith C, Greenawalt, Danielle M, Griffin, Paula, Ding, Jinghong, Newman, Anne B, Tylavsky, Fran, Miljkovic, Iva, Kritchevsky, Stephen B, Launer, Lenore, Garcia, Melissa, Eiriksdottir, Gudny, Carr, J Jeffrey, Gudnason, Vilmunder, Harris, Tamara B, Cupples, L Adrienne, Borecki, Ingrid B

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