Crystal Structure of a Soluble Cleaved HIV-1 Envelope Trimer von Julien, Jean-Philippe, Cupo, Albert, Sok, Devin, Stanfield, Robyn L., Lyumkis, Dmitry, Deller, Marc C., Klasse, Per-Johan, Burton, Dennis R., Sanders, Rogier W., Moore, John P., Ward, Andrew B., Wilson, Ian A.

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Protein stability: a crystallographer's perspective von Deller, Marc C., Kong, Leopold, Rupp, Bernhard

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Lipid interactions and angle of approach to the HIV-1 viral membrane of broadly neutralizing antibody 10E8: Insights for vaccine and therapeutic design von Irimia, Adriana, Serra, Andreia M, Sarkar, Anita, Jacak, Ronald, Kalyuzhniy, Oleksandr, Sok, Devin, Saye-Francisco, Karen L, Schiffner, Torben, Tingle, Ryan, Kubitz, Michael, Adachi, Yumiko, Stanfield, Robyn L, Deller, Marc C, Burton, Dennis R, Schief, William R, Wilson, Ian A

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Key gp120 Glycans Pose Roadblocks to the Rapid Development of VRC01-Class Antibodies in an HIV-1-Infected Chinese Donor von Kong, Leopold, Ju, Bin, Chen, Yajing, He, Linling, Ren, Li, Liu, Jiandong, Hong, Kunxue, Su, Bin, Wang, Zheng, Ozorowski, Gabriel, Ji, Xiaolin, Hua, Yuanzi, Chen, Yanli, Deller, Marc C., Hao, Yanling, Feng, Yi, Garces, Fernando, Wilson, Richard, Dai, Kaifan, O’Dell, Sijy, McKee, Krisha, Mascola, John R., Ward, Andrew B., Wyatt, Richard T., Li, Yuxing, Wilson, Ian A., Zhu, Jiang, Shao, Yiming

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Structure–Function Analysis of the Extended Conformation of a Polyketide Synthase Module von Li, Xiuyuan, Sevillano, Natalia, La Greca, Florencia, Deis, Lindsay, Liu, Yu-Chen, Deller, Marc C, Mathews, Irimpan I, Matsui, Tsutomu, Cane, David E, Craik, Charles S, Khosla, Chaitan

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Structure of Hepatitis C Virus Envelope Glycoprotein E2 Antigenic Site 412 to 423 in Complex with Antibody AP33 von KONG, Leopold, GIANG, Erick, NIEUSMA, Travis, ROBBINS, Justin B, DELLER, Marc C, STANFIELD, Robyn L, WILSONA, Ian A, LAW, Mansun

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Structure-based discovery of NANOG variant with enhanced properties to promote self-renewal and reprogramming of pluripotent stem cells von Hayashi, Yohei, Caboni, Laura, Das, Debanu, Yumoto, Fumiaki, Clayton, Thomas, Deller, Marc C., Nguyen, Phuong, Farr, Carol L., Chiu, Hsiu-Ju, Miller, Mitchell D., Elsliger, Marc-André, Deacon, Ashley M., Godzik, Adam, Lesley, Scott A., Tomoda, Kiichiro, Conklin, Bruce R., Wilson, Ian A., Yamanaka, Shinya, Fletterick, Robert J.

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Approaches to automated protein crystal harvesting von Deller, Marc C., Rupp, Bernhard

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Models of protein–ligand crystal structures: trust, but verify von Deller, Marc C., Rupp, Bernhard

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Functional and structural characterization of a thermostable acetyl esterase from Thermotoga maritima von Levisson, Mark, Han, Gye Won, Deller, Marc C., Xu, Qingping, Biely, Peter, Hendriks, Sjon, Ten Eyck, Lynn F., Flensburg, Claus, Roversi, Pietro, Miller, Mitchell D., McMullan, Daniel, von Delft, Frank, Kreusch, Andreas, Deacon, Ashley M., van der Oost, John, Lesley, Scott A., Elsliger, Marc-André, Kengen, Servé W. M., Wilson, Ian A.

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Structural insights into the recognition of phosphopeptide by the FHA domain of kanadaptin von Xu, Qingping, Deller, Marc C, Nielsen, Tine K, Grant, Joanna C, Lesley, Scott A, Elsliger, Marc-André, Deacon, Ashley M, Wilson, Ian A

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Crystal structure of a two-subunit TrkA octameric gating ring assembly von Deller, Marc C, Johnson, Hope A, Miller, Mitchell D, Spraggon, Glen, Elsliger, Marc-André, Wilson, Ian A, Lesley, Scott A

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The Role of the Secondary Coordination Sphere in a Fungal Polysaccharide Monooxygenase von Span, Elise A, Suess, Daniel L. M, Deller, Marc C, Britt, R. David, Marletta, Michael A

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Supersite of immune vulnerability on the glycosylated face of HIV-1 envelope glycoprotein gp120 von Kong, Leopold, Lee, Jeong Hyun, Doores, Katie J, Murin, Charles D, Julien, Jean-Philippe, McBride, Ryan, Liu, Yan, Marozsan, Andre, Cupo, Albert, Klasse, Per-Johan, Hoffenberg, Simon, Caulfield, Michael, King, C Richter, Hua, Yuanzi, Le, Khoa M, Khayat, Reza, Deller, Marc C, Clayton, Thomas, Tien, Henry, Feizi, Ten, Sanders, Rogier W, Paulson, James C, Moore, John P, Stanfield, Robyn L, Burton, Dennis R, Ward, Andrew B, Wilson, Ian A

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Validation of Protein–Ligand Crystal Structure Models: Small Molecule and Peptide Ligands von Pozharski, Edwin, Deller, Marc C., Rupp, Bernhard

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Discovery of (4-Pyrazolyl)-2-aminopyrimidines as Potent and Selective Inhibitors of Cyclin-Dependent Kinase 2 von Hummel, Joshua R., Xiao, Kai-Jiong, Yang, Jeffrey C., Epling, Leslie B., Mukai, Ken, Ye, Qinda, Xu, Meizhong, Qian, Dingquan, Huo, Lu, Weber, Michael, Roman, Valerie, Lo, Yvonne, Drake, Katherine, Stump, Kristine, Covington, Maryanne, Kapilashrami, Kanishk, Zhang, Guofeng, Ye, Min, Diamond, Sharon, Yeleswaram, Swamy, Macarron, Ricardo, Deller, Marc C., Wee, Susan, Kim, Sunkyu, Wang, Xiaozhao, Wu, Liangxing, Yao, Wenqing

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Discovery of Potent and Selective Inhibitors of Wild-Type and Gatekeeper Mutant Fibroblast Growth Factor Receptor (FGFR) 2/3 von Shvartsbart, Artem, Roach, Jeremy J., Witten, Michael R., Koblish, Holly, Harris, Jennifer J., Covington, Maryanne, Hess, Rodrigo, Lin, Luping, Frascella, Michelle, Truong, Lisa, Leffet, Lynn, Conlen, Patricia, Beshad, Elham, Klabe, Ron, Katiyar, Kamna, Kaldon, Laura, Young-Sciame, Ruth, He, Xin, Petusky, Susan, Chen, Kwang-Jong, Horsey, April, Lei, Hsiang-Ting, Epling, Leslie B., Deller, Marc C., Vechorkin, Oleg, Yao, Wenqing

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Discovery of INCB159020, an Orally Bioavailable KRAS G12D Inhibitor von Ye, Qinda, Shvartsbart, Artem, Li, Zhenwu, Gan, Pei, Policarpo, Rocco L, Qi, Chao, Roach, Jeremy J, Zhu, Wenyu, McCammant, Matthew S, Hu, Bin, Li, Gencheng, Yin, Haolin, Carlsen, Peter, Hoang, Gia, Zhao, Le, Susick, Robert, Zhang, Fenglei, Lai, Cheng-Tsung, Allali Hassani, Abdellah, Epling, Leslie B, Gallion, Alexandra, Kurzeja-Lipinski, Kerri, Gallagher, Karen, Roman, Valerie, Farren, Matthew R, Kong, Weixi, Deller, Marc C, Zhang, Guofeng, Covington, Maryanne, Diamond, Sharon, Kim, Sunkyu, Yao, Wenqing, Sokolsky, Alexander, Wang, Xiaozhao

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Complete epitopes for vaccine design derived from a crystal structure of the broadly neutralizing antibodies PGT128 and 8ANC195 in complex with an HIV-1 Env trimer von Kong, Leopold, Torrents de la Peña, Alba, Deller, Marc C., Garces, Fernando, Sliepen, Kwinten, Hua, Yuanzi, Stanfield, Robyn L., Sanders, Rogier W., Wilson, Ian A.

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Crystal structure of a metal-dependent phosphoesterase (YP_910028.1) from Bifidobacterium adolescentis: Computational prediction and experimental validation of phosphoesterase acti... von Han, Gye Won, Ko, Jaeju, Farr, Carol L., Deller, Marc C., Xu, Qingping, Chiu, Hsiu-Ju, Miller, Mitchell D., Sefcikova, Jana, Somarowthu, Srinivas, Beuning, Penny J., Elsliger, Marc-André, Deacon, Ashley M., Godzik, Adam, Lesley, Scott A., Wilson, Ian A., Ondrechen, Mary Jo

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