Quantitative monitoring by polymerase colony assay of known mutations resistant to ABL kinase inhibitors von Nardi, V, Raz, T, Cao, X, Wu, C J, Stone, R M, Cortes, J, Deininger, M W N, Church, G, Zhu, J, Daley, G Q

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Dynamics of BCR-ABL mRNA expression in first-line therapy of chronic myelogenous leukemia patients with imatinib or interferon α/ara-C von MÜLLER, M. C, GATTERMANN, N, KRAUSE, S. W, NERL, C, SAYER, H. G, OTTMANN, O. G, WALLER, C, AULITZKY, W, LE COUTRE, P, FREUND, M, MERX, K, PASCHKA, P, LAHAYE, T, KÖNIG, H, KREIL, S, BERGER, U, GSCHAIDMEIER, H, HEHLMANN, R, HOCHHAUS, A, DEININGER, M. W. N, BERNDT, A, FRUEHAUF, S, NEUHAUER, A, FISCHER, T, HOSSFELD, D. K, SCHNELLER, F

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The function of the pleckstrin homology domain in BCR-ABL-mediated leukemogenesis von Demehri, S, O'Hare, T, Eide, C A, Smith, C A, Tyner, J W, Druker, B J, Deininger, M W N

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Zoledronate inhibits proliferation and induces apoptosis of imatinib-resistant chronic myeloid leukaemia cells von CHUAH, C, BARNES, D. J, KWOK, M, CORBIN, A, DEININGER, M. W. N, DRUKER, B. J, MELO, J. V

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Detection of ABL kinase domain mutations with denaturing high-performance liquid chromatography von DEININGER, M. W. N, MCGREEVEY, L, WILLIS, S, BAINBRIDGE, T. M, DRUKER, B. J, HEINRICH, M. C

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Asciminib in Chronic Myeloid Leukemia after ABL Kinase Inhibitor Failure von Hughes, Timothy P, Mauro, Michael J, Cortes, Jorge E, Minami, Hironobu, Rea, Delphine, DeAngelo, Daniel J, Breccia, Massimo, Goh, Yeow-Tee, Talpaz, Moshe, Hochhaus, Andreas, le Coutre, Philipp, Ottmann, Oliver, Heinrich, Michael C, Steegmann, Juan L, Deininger, Michael W.N, Janssen, Jeroen J.W.M, Mahon, Francois-Xavier, Minami, Yosuke, Yeung, David, Ross, David M, Tallman, Martin S, Park, Jae H, Druker, Brian J, Hynds, David, Duan, Yuyan, Meille, Christophe, Hourcade-Potelleret, Florence, Vanasse, K. Gary, Lang, Fabian, Kim, Dong-Wook

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A single nucleotide polymorphism in the coding region of ABL and its effects on sensitivity to imatinib von CROSSMAN, L. C, O'HARE, T, DEININGER, M. W. N, LANGE, T, WILLIS, S. G, STOFFREGEN, E. P, CORBIN, A. S, O'BRIEN, S. G, HEINRICH, M. C, DRUKER, B. J, MIDDLETON, P. G

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A Phase 2 Trial of Ponatinib in Philadelphia Chromosome–Positive Leukemias von Cortes, J.E, Kim, D.-W, Pinilla-Ibarz, J, le Coutre, P, Paquette, R, Chuah, C, Nicolini, F.E, Apperley, J.F, Khoury, H.J, Talpaz, M, DiPersio, J, DeAngelo, D.J, Abruzzese, E, Rea, D, Baccarani, M, Müller, M.C, Gambacorti-Passerini, C, Wong, S, Lustgarten, S, Rivera, V.M, Clackson, T, Turner, C.D, Haluska, F.G, Guilhot, F, Deininger, M.W, Hochhaus, A, Hughes, T, Goldman, J.M, Shah, N.P, Kantarjian, H

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Efficacy, safety, and survival with ruxolitinib in patients with myelofibrosis: results of a median 3-year follow-up of COMFORT-I von Verstovsek, Srdan, Mesa, Ruben A, Gotlib, Jason, Levy, Richard S, Gupta, Vikas, DiPersio, John F, Catalano, John V, Deininger, Michael W N, Miller, Carole B, Silver, Richard T, Talpaz, Moshe, Winton, Elliott F, Harvey, Jr, Jimmie H, Arcasoy, Murat O, Hexner, Elizabeth O, Lyons, Roger M, Raza, Azra, Vaddi, Kris, Sun, William, Peng, Wei, Sandor, Victor, Kantarjian, Hagop

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Efficacy, safety and survival with ruxolitinib in patients with myelofibrosis: results of a median 2-year follow-up of COMFORT-I von Verstovsek, Srdan, Mesa, Ruben A, Gotlib, Jason, Levy, Richard S, Gupta, Vikas, DiPersio, John F, Catalano, John V, Deininger, Michael W N, Miller, Carole B, Silver, Richard T, Talpaz, Moshe, Winton, Elliott F, Harvey, Jr, Jimmie H, Arcasoy, Murat O, Hexner, Elizabeth O, Lyons, Roger M, Paquette, Ronald, Raza, Azra, Vaddi, Kris, Erickson-Viitanen, Susan, Sun, William, Sandor, Victor, Kantarjian, Hagop M

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e8a2 BCR-ABL: more frequent than other atypical BCR-ABL variants? von Demehri, S, Paschka, P, Schultheis, B, Lange, T, Koizumi, T, Sugimoto, T, Branford, S, Lim, L C, Kegel, T, Martinelli, G, Hochhaus, A, Druker, B J, Deininger, M W N

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FISH for BCR-ABL on interphases of peripheral blood neutrophils but not of unselected white cells correlates with bone marrow cytogenetics in CML patients treated with imatinib von Reinhold, U, Hennig, E, Leiblein, S, Niederwieser, D, Deininger, M W N

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Durability of molecular remission in chronic myeloid leukemia patients treated with imatinib vs allogeneic stem cell transplantation von Lange, T, Bumm, T, Mueller, M, Otto, S, Al-Ali, H-K, Grommisch, L, Musiol, S, Franke, C, Krahl, R, Niederwieser, D, Deininger, M W N

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The Tyrosine Kinase Inhibitor CGP57148B Selectively Inhibits the Growth of BCR-ABL–Positive Cells von Deininger, Michael W.N., Goldman, John M., Lydon, Nicholas, Melo, Junia V.

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Selective induction of leukemia-associated fusion genes by high-dose ionizing radiation von DEININGER, M. W. N, BOSE, S, GORA-TYBOR, J, YAN, X.-H, GOLDMAN, J. M, MELO, J. V

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Catalytic domains of tyrosine kinases determine the phosphorylation sites within c-Cbl von Grossmann, A.H., Kolibaba, K.S., Willis, S.G., Corbin, A.S., Langdon, W.S., Deininger, M.W.N., Druker, B.J.

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FISH for BRC-ABL on interphases of peripheral blood neutrophils but not of unselected white cells correlates with bone marrow cytogenetics in CML patients treated with imatinib von REINHOLD, U, HENNIG, E, LEIBLEIN, S, NIEDERWIESER, D, DEININGER, M. W. N

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Dynamics of BCR-ABL mRNA expression in first-line therapy of chronic myelogenous leukemia patients with imatinib or interferon ara-C von Müller, M C, Gattermann, N, Lahaye, T, Deininger, M W N, Berndt, A, Fruehauf, S, Neubauer, A, Fischer, T, Hossfeld, D K, Schneller, F, Krause, S W, C Nerl, Sayer, H G, Ottmann, O G, Waller, C, Aulitzky, W, P le Coutre, Freund, M, Merx, K, Paschka, P, König, H, Kreil, S

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Selection and characterization of BCR-ABL positive cell lines with differential sensitivity to the tyrosine kinase inhibitor STI571 : diverse mechanisms of resistance von MAHON, F. X, DEININGER, M. W. N, SCHULTHEIS, B, CHABROL, J, REIFFERS, J, GOLDMAN, J. M, MELO, J. V

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Ponatinib in Refractory Philadelphia Chromosome–Positive Leukemias von Cortes, Jorge E, Kantarjian, Hagop, Shah, Neil P, Bixby, Dale, Mauro, Michael J, Flinn, Ian, O'Hare, Thomas, Hu, Simin, Narasimhan, Narayana I, Rivera, Victor M, Clackson, Tim, Turner, Christopher D, Haluska, Frank G, Druker, Brian J, Deininger, Michael W.N, Talpaz, Moshe

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