A defined structural unit enables de novo design of small-molecule-binding proteins von Polizzi, Nicholas F, DeGrado, William F

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De novo protein design, a retrospective von Korendovych, Ivan V, DeGrado, William F

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De Novo Design of Four-Helix Bundle Metalloproteins: One Scaffold, Diverse Reactivities von Lombardi, Angela, Pirro, Fabio, Maglio, Ornella, Chino, Marco, DeGrado, William F

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Signal Transduction in Histidine Kinases: Insights from New Structures von Bhate, Manasi P., Molnar, Kathleen S., Goulian, Mark, DeGrado, William F.

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The Role of Hydrophobicity in the Antimicrobial and Hemolytic Activities of Polymethacrylate Derivatives von Kuroda, Kenichi, Caputo, Gregory A., DeGrado, William F.

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Self-assembling dipeptide antibacterial nanostructures with membrane disrupting activity von Schnaider, Lee, Brahmachari, Sayanti, Schmidt, Nathan W., Mensa, Bruk, Shaham-Niv, Shira, Bychenko, Darya, Adler-Abramovich, Lihi, Shimon, Linda J. W., Kolusheva, Sofiya, DeGrado, William F., Gazit, Ehud

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Structural basis for proton conduction and inhibition by the influenza M2 protein von Hong, Mei, DeGrado, William F.

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Comparative mechanistic studies of brilacidin, daptomycin, and the antimicrobial peptide LL16 von Mensa, Bruk, Howell, Gabriella L, Scott, Richard, DeGrado, William F

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Inhibitors of the M2 Proton Channel Engage and Disrupt Transmembrane Networks of Hydrogen-Bonded Waters von Thomaston, Jessica L, Polizzi, Nicholas F, Konstantinidi, Athina, Wang, Jun, Kolocouris, Antonios, DeGrado, William F

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Salt bridges: Geometrically specific, designable interactions von Donald, Jason E., Kulp, Daniel W., DeGrado, William F.

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Water Distribution, Dynamics, and Interactions with Alzheimer’s β‑Amyloid Fibrils Investigated by Solid-State NMR von Wang, Tuo, Jo, Hyunil, DeGrado, William F, Hong, Mei

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Structure of the amantadine binding site of influenza M2 proton channels in lipid bilayers von Schmidt-Rohr, Klaus, Wang, Jun, Hong, Mei, DeGrado, William F, Cady, Sarah D, Soto, Cinque S

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De novo design of a transmembrane Zn2+-transporting four-helix bundle von Joh, Nathan H., Wang, Tuo, Bhate, Manasi P., Acharya, Rudresh, Wu, Yibing, Grabe, Michael, Hong, Mei, Grigoryan, Gevorg, DeGrado, William F.

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De Novo Design of Antimicrobial Polymers, Foldamers, and Small Molecules: From Discovery to Practical Applications von Tew, Gregory N, Scott, Richard W, Klein, Michael L, DeGrado, William F

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Brilacidin, a COVID‐19 drug candidate, demonstrates broad‐spectrum antiviral activity against human coronaviruses OC43, 229E, and NL63 through targeting both the virus and the host... von Hu, Yanmei, Jo, Hyunil, DeGrado, William F., Wang, Jun

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Packing of apolar side chains enables accurate design of highly stable membrane proteins von Mravic, Marco, Thomaston, Jessica L, Tucker, Maxwell, Solomon, Paige E, Liu, Lijun, DeGrado, William F

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Stacked binding of a PET ligand to Alzheimer’s tau paired helical filaments von Merz, Gregory E., Chalkley, Matthew J., Tan, Sophia K., Tse, Eric, Lee, Joanne, Prusiner, Stanley B., Paras, Nick A., DeGrado, William F., Southworth, Daniel R.

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Amphiphilic Polymethacrylate Derivatives as Antimicrobial Agents von Kuroda, Kenichi, DeGrado, William F

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Foldamers as versatile frameworks for the design and evolution of function von Shandler, Scott, Choi, Sungwook, DeGrado, William F, Goodman, Catherine M

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Influenza A M2 Inhibitor Binding Understood through Mechanisms of Excess Proton Stabilization and Channel Dynamics von Watkins, Laura C, DeGrado, William F, Voth, Gregory A

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