Fast skeletal muscle troponin activation increases force of mouse fast skeletal muscle and ameliorates weakness due to nebulin-deficiency von Lee, Eun-Jeong, De Winter, Josine M, Buck, Danielle, Jasper, Jeffrey R, Malik, Fady I, Labeit, Siegfried, Ottenheijm, Coen A, Granzier, Henk

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Mutation-specific effects on thin filament length in thin filament myopathy von Winter, Josine M. de, Joureau, Barbara, Lee, Eun-Jeong, Kiss, Balázs, Yuen, Michaela, Gupta, Vandana A., Pappas, Christopher T., Gregorio, Carol C., Stienen, Ger J. M., Edvardson, Simon, Wallgren-Pettersson, Carina, Lehtokari, Vilma-Lotta, Pelin, Katarina, Malfatti, Edoardo, Romero, Norma B., Engelen, Baziel G. van, Voermans, Nicol C., Donkervoort, Sandra, Bönnemann, C. G., Clarke, Nigel F., Beggs, Alan H., Granzier, Henk, Ottenheijm, Coen A. C.

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KBTBD13 is an actin-binding protein that modulates muscle kinetics von de Winter, Josine M, Molenaar, Joery P, Yuen, Michaela, van der Pijl, Robbert, Shen, Shengyi, Conijn, Stefan, van de Locht, Martijn, Willigenburg, Menne, Bogaards, Sylvia Jp, van Kleef, Esmee Sb, Lassche, Saskia, Persson, Malin, Rassier, Dilson E, Sztal, Tamar E, Ruparelia, Avnika A, Oorschot, Viola, Ramm, Georg, Hall, Thomas E, Xiong, Zherui, Johnson, Christopher N, Li, Frank, Kiss, Balazs, Lozano-Vidal, Noelia, Boon, Reinier A, Marabita, Manuela, Nogara, Leonardo, Blaauw, Bert, Rodenburg, Richard J, Küsters, Benno, Doorduin, Jonne, Beggs, Alan H, Granzier, Henk, Campbell, Ken, Ma, Weikang, Irving, Thomas, Malfatti, Edoardo, Romero, Norma B, Bryson-Richardson, Robert J, van Engelen, Baziel Gm, Voermans, Nicol C, Ottenheijm, Coen Ac

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Small molecule drugs to improve sarcomere function in those with acquired and inherited myopathies von Claassen, Wout J, Baelde, Rianne J, Galli, Ricardo A, de Winter, Josine M, Ottenheijm, Coen A C

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Acute and chronic tirasemtiv treatment improves in vivo and in vitro muscle performance in actin-based nemaline myopathy mice von de Winter, Josine M, Gineste, Charlotte, Minardi, Elisa, Brocca, Lorenza, Rossi, Maira, Borsboom, Tamara, Beggs, Alan H, Bernard, Monique, Bendahan, David, Hwee, Darren T, Malik, Fady I, Pellegrino, Maria Antonietta, Bottinelli, Roberto, Gondin, Julien, Ottenheijm, Coen A C

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KBTBD13 is an actin-binding protein that modulates muscle kinetics von de Winter, Josine M., Molenaar, Joery P., Yuen, Michaela, van der Pijl, Robbert, Shen, Shengyi, Conijn, Stefan, van de Locht, Martijn, Willigenburg, Menne, Bogaards, Sylvia J. P., van Kleef, Esmee S. B., Lassche, Saskia, Persson, Malin, Rassier, Dilson E., Sztal, Tamar E., Ruparelia, Avnika A., Oorschot, Viola, Ramm, Georg, Hall, Thomas E., Xiong, Zherui, Johnson, Christopher N., Li, Frank, Kiss, Balazs, Lozano-Vidal, Noelia, Boon, Reinier A., Marabita, Manuela, Nogara, Leonardo, Blaauw, Bert, Rodenburg, Richard J., Kusters, Benno, Doorduin, Jonne, Beggs, Alan H., Granzier, Henk, Campbell, Ken, Ma, Weikang, Irving, Thomas, Malfatti, Edoardo, Romero, Norma B., Bryson-Richardson, Robert J., van Engelen, Baziel G. M., Voermans, Nicol C., Ottenheijm, Coen A. C.

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Tirasemtiv enhances submaximal muscle tension in an Acta1:p.Asp286Gly mouse model of nemaline myopathy von Galli, Ricardo A, Borsboom, Tamara C, Gineste, Charlotte, Brocca, Lorenza, Rossi, Maira, Hwee, Darren T, Malik, Fady I, Bottinelli, Roberto, Gondin, Julien, Pellegrino, Maria-Antonietta, de Winter, Josine M, Ottenheijm, Coen A C

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A two-faced cysteine residue modulates skeletal muscle contraction. Focus on "S-nitrosylation and S-glutathionylation of Cys134 on troponin I have opposing competitive actions on C... von de Winter, Josine M, Ottenheijm, Coen A C

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A two-faced cysteine residue modulates skeletal muscle contraction . Focus on " S -nitrosylation and S -glutathionylation of Cys134 on troponin I have opposing competitive actions... von de Winter, Josine M, Ottenheijm, Coen A C

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Pathogenic variants in TNNC2 cause congenital myopathy due to an impaired force response to calcium von van de Locht, Martijn, Donkervoort, Sandra, de Winter, Josine M., Conijn, Stefan, Begthel, Leon, Kusters, Benno, Mohassel, Payam, Hu, Ying, Medne, Livija, Quinn, Colin, Moore, Steven A., Foley, A. Reghan, Seo, Gwimoon, Hwee, Darren T., Malik, Fady, Irving, Thomas, Ma, Weikang, Granzier, Henk L., Kamsteeg, Erik-Jan, Immadisetty, Kalyan, Kekenes-Huskey, Peter, Pinto, Jose R., Voermans, Nicol, Bonnemann, Carsten G., Ottenheijm, Coen A. C.

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Sarcomere Dysfunction in Nemaline Myopathy von de Winter, Josine M., Ottenheijm, Coen A.C.

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KBTBD13 is a novel cardiomyopathy gene von Winter, Josine M., Bouman, Karlijn, Strom, Joshua, Methawasin, Mei, Jongbloed, Jan D. H., Roest, Wilma, Wijngaarden, Jan van, Timmermans, Janneke, Nijveldt, Robin, Heuvel, Frederik, Kamsteeg, Erik‐Jan, Engelen, Baziel G., Galli, Ricardo, Bogaards, Sylvia J. P., Boon, Reinier A., Pijl, Robbert J., Granzier, Henk, Koeleman, Bobby, Amin, Ahmad S., Velden, Jolanda, Tintelen, J. Peter, Berg, Maarten P., Spaendonck‐Zwarts, Karin Y., Voermans, Nicol C., Ottenheijm, Coen A. C.

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NEM6, KBTBD13-Related Congenital Myopathy: Myopathological Analysis in 18 Dutch Patients Reveals Ring Rods Fibers, Cores, Nuclear Clumps, and Granulo-Filamentous Protein Material von Bouman, Karlijn, Küsters, Benno, De Winter, Josine M, Gillet, Cynthia, Van Kleef, Esmee S B, Eshuis, Lilian, Brochier, Guy, Madelaine, Angeline, Labasse, Clémence, Boulogne, Claire, Van Engelen, Baziel G M, Ottenheijm, Coen A C, Romero, Norma B, Voermans, Nicol C, Malfatti, Edoardo

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Muscle weakness in TPM3-myopathy is due to reduced Ca2+-sensitivity and impaired acto-myosin cross-bridge cycling in slow fibres von Yuen, Michaela, Cooper, Sandra T, Marston, Steve B, Nowak, Kristen J, McNamara, Elyshia, Mokbel, Nancy, Ilkovski, Biljana, Ravenscroft, Gianina, Rendu, John, de Winter, Josine M, Klinge, Lars, Beggs, Alan H, North, Kathryn N, Ottenheijm, Coen A C, Clarke, Nigel F

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TPM3 deletions cause a hypercontractile congenital muscle stiffness phenotype von Donkervoort, Sandra, Papadaki, Maria, de Winter, Josine M., Neu, Matthew B., Kirschner, Janbernd, Bolduc, Véronique, Yang, Michele L., Gibbons, Melissa A., Hu, Ying, Dastgir, Jahannaz, Leach, Meganne E., Rutkowski, Anne, Foley, A. Reghan, Krüger, Marcus, Wartchow, Eric P., McNamara, Elyshia, Ong, Royston, Nowak, Kristen J., Laing, Nigel G., Clarke, Nigel F., Ottenheijm, Coen A. C., Marston, Steven B., Bönnemann, Carsten G.

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Muscle weakness in respiratory and peripheral skeletal muscles in a mouse model for nebulin-based nemaline myopathy von Joureau, Barbara, de Winter, Josine M, Stam, Kelly, Granzier, Henk, Ottenheijm, Coen A.C

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Recessive MYH7-related myopathy in two families von Beecroft, Sarah J., van de Locht, Martijn, de Winter, Josine M., Ottenheijm, Coen A., Sewry, Caroline A., Mohammed, Shehla, Ryan, Monique M., Woodcock, Ian R., Sanders, Lauren, Gooding, Rebecca, Davis, Mark R., Oates, Emily C., Laing, Nigel G., Ravenscroft, Gianina, McLean, Catriona A., Jungbluth, Heinz

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Isolating Myofibrils from Skeletal Muscle Biopsies and Determining Contractile Function with a Nano-Newton Resolution Force Transducer von van de Locht, Martijn, de Winter, Josine M., Rassier, Dilson E., Helmes, Michiel H. B., Ottenheijm, Coen A. C.

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A Likely Pathogenic variant in the KBTBD13 Gene: A Case Series of Three Patients with Nemaline Myopathy Type 6 von van Kleef, Esmee S B, Bouman, Karlijn, Molenaar, Joery P F, de Winter, Josine M, Duijkers, Floor A M, Eftimov, Filip, Verschuuren-Bemelmans, Corien C, van der Laan, Tineke, Küsters, Benno, Malfatti, Edoardo, Kamsteeg, Erik-Jan, van Engelen, Baziel G M, Ottenheijm, Coen A C, Doorduin, Jonne, Voermans, Nicol C

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Muscle histopathology in nebulin-related nemaline myopathy: ultrastrastructural findings correlated to disease severity and genotype von Malfatti, Edoardo, Lehtokari, Vilma-Lotta, Böhm, Johann, De Winter, Josine M, Schäffer, Ursula, Estournet, Brigitte, Quijano-Roy, Susana, Monges, Soledad, Lubieniecki, Fabiana, Bellance, Remi, Viou, Mai Thao, Madelaine, Angéline, Wu, Bin, Taratuto, Ana Lía, Eymard, Bruno, Pelin, Katarina, Fardeau, Michel, Ottenheijm, Coen A C, Wallgren-Pettersson, Carina, Laporte, Jocelyn, Romero, Norma B

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