A bead-based multiplexed immunoassay to evaluate breast cancer biomarkers for early detection in pre-diagnostic serum von Opstal-van Winden, Annemieke W J, Rodenburg, Wendy, Pennings, Jeroen L A, van Oostrom, Conny T M, Beijnen, Jos H, Peeters, Petra H M, van Gils, Carla H, de Vries, Annemieke

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High Incidence of Protein-Truncating TP53 Mutations in BRCA1-Related Breast Cancer von HOLSTEGE, Henne, JOOSSE, Simon A, VAN OOSTROM, Conny Th. M, NEDERLOF, Petra M, DE VRIES, Annemieke, JONKERS, Jos

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RNA isolation for transcriptomics of human and mouse small skin biopsies von Bruning, Oskar, Rodenburg, Wendy, Radonic, Teodora, Zwinderman, Aeilko H, de Vries, Annemieke, Breit, Timo M, de Jong, Mark

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Confounding Factors in the Transcriptome Analysis of an In-Vivo Exposure Experiment von Bruning, Oskar, Rodenburg, Wendy, Wackers, Paul F K, van Oostrom, Conny, Jonker, Martijs J, Dekker, Rob J, Rauwerda, Han, Ensink, Wim A, de Vries, Annemieke, Breit, Timo M

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Activation of the p53-dependent G1 checkpoint response in mouse embryo fibroblasts depends on the specific DNA damage inducer von Attardi, Laura D, de Vries, Annemieke, Jacks, Tyler

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Mouse Models for the p53 R72P Polymorphism Mimic Human Phenotypes von FENG ZHU, DOLLE, Martijn E. T, JOHNSON, David G, BERTON, Thomas R, KUIPER, Raoul V, CAPPS, Carrie, ESPEJO, Alexsandra, MCARTHUR, Mark J, BEDFORD, Mark T, VAN STEEG, Harry, DE VRIES, Annemieke

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In vivo p53 response and immune reaction underlie highly effective low-dose radiotherapy in follicular lymphoma von Knoops, Laurent, Haas, Rick, de Kemp, Sanne, Majoor, Donné, Broeks, Annegien, Eldering, Eric, de Boer, Jan Paul, Verheij, Marcel, van Ostrom, Conny, de Vries, Annemieke, van't Veer, Laura, de Jong, Daphne

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Targeted Point Mutations of p53 Lead to Dominant-Negative Inhibition of Wild-Type p53 Function von de Vries, Annemieke, Flores, Elsa R., Miranda, Barbara, Hsieh, Harn-Mei, Conny Th. M. van Oostrom, Sage, Julien, Jacks, Tyler

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A range finding protocol to support design for transcriptomics experimentation: examples of in-vitro and in-vivo murine UV exposure von Bruning, Oskar, Rodenburg, Wendy, van Oostrom, Conny T, Jonker, Martijs J, de Jong, Mark, Dekker, Rob J, Rauwerda, Han, Ensink, Wim A, de Vries, Annemieke, Breit, Timo M

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Increased Sensitivity to UV Radiation in Mice with a p53 Point Mutation at Ser389 von Bruins, Wendy, Zwart, Edwin, Attardi, Laura D., Iwakuma, Tomoo, Hoogervorst, Esther M., Beems, Rudolf B., Miranda, Barbara, van Oostrom, Conny T. M., van den Berg, Jolanda, van den Aardweg, Gerard J., Lozano, Guillermina, van Steeg, Harry, Jacks, Tyler, de Vries, Annemieke

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Gene expression profiling in a mouse model identifies fetal liver- and placenta-derived potential biomarkers for Down Syndrome screening von Pennings, Jeroen L A, Rodenburg, Wendy, Imholz, Sandra, Koster, Maria P H, van Oostrom, Conny T M, Breit, Timo M, Schielen, Peter C J I, de Vries, Annemieke

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Lasting effects on body weight and mammary gland gene expression in female mice upon early life exposure to n-3 but not n-6 high-fat diets von Luijten, Mirjam, Singh, Amar V, Bastian, Caleb A, Westerman, Anja, Pisano, M Michele, Pennings, Jeroen L A, Verhoef, Aart, Green, Maia L, Piersma, Aldert H, de Vries, Annemieke, Knudsen, Thomas B

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Finding transcriptomics biomarkers for in vivo identification of (non-)genotoxic carcinogens using wild-type and Xpa/p53 mutant mouse models von Jonker, Martijs J., Bruning, Oskar, van Iterson, Maarten, Schaap, Mirjam M., van der Hoeven, Tessa V., Vrieling, Harry, Beems, Rudolf B., de Vries, Annemieke, van Steeg, Harry, Breit, Timo M., Luijten, Mirjam

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Overlapping gene expression profiles of model compounds provide opportunities for immunotoxicity screening von Baken, Kirsten A., Pennings, Jeroen L.A., Jonker, Martijs J., Schaap, Mirjam M., de Vries, Annemieke, van Steeg, Harry, Breit, Timo M., van Loveren, Henk

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Discovery of novel serum biomarkers for prenatal Down syndrome screening by integrative data mining von Pennings, Jeroen L A, Koster, Maria P H, Rodenburg, Wendy, Schielen, Peter C J I, de Vries, Annemieke

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The Absence of Ser389 Phosphorylation in p53 Affects the Basal Gene Expression Level of Many p53-Dependent Genes and Alters the Biphasic Response to UV Exposure in Mouse Embryonic... von Bruins, Wendy, Bruning, Oskar, Jonker, Martijs J., Zwart, Edwin, van der Hoeven, Tessa V., Pennings, Jeroen L. A., Rauwerda, Han, de Vries, Annemieke, Breit, Timo M.

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Mice expressing a mammary gland-specific R270H mutation in the p53 tumor suppressor gene mimic human breast cancer development von WIJNHOVEN, Susan W. P, ZWART, Edwin, VAN STEEG, Harry, DE VRIES, Annemieke, SPEKSNIJDER, Ewoud N, BEEMS, Rudolf B, OLIVE, Kenneth P, TUVESON, David A, JONKERS, Jos, SCHAAP, Mirjam M, VAN DEN BERG, Jolanda, JACKS, Tyler

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XPA-deficiency in hairless mice causes a shift in skin tumor types and mutational target genes after exposure to low doses of U.V.B von DE VRIES, A, BERG, R. J. W, WIJNHOVEN, S, WESTERMAN, A, WESTER, P. W, VAN KREIJL, C. F, CAPEL, P. J. A, DE GRUIJL, F. R, VAN KRANEN, H. J, VAN STEEG, H

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Increased susceptibility to ultraviolet-B and carcinogens of mice lacking the DNA excision repair gene XPA von Vries, Annemieke de, van Oostrom, Conny Th. M, Hofhuis, Frans M. A, Dortant, Paul M, Berg, Rob J. W, Gruijl, Frank R. de, Wester, Piet W, van Kreijl, Coen F, Capel, Peter J. A, Steeg, Harry van, Verbeek, Sjef J

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Mutation at p53 serine 389 does not rescue the embryonic lethality in mdm2 or mdm4 null mice von Iwakuma, Tomoo, Parant, John M, Fasulo, Mark, Zwart, Edwin, Jacks, Tyler, de Vries, Annemieke, Lozano, Guillermina

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