Differentiation therapy revisited von de Thé, Hugues

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Activation of a promyelocytic leukemia–tumor protein 53 axis underlies acute promyelocytic leukemia cure von Ablain, Julien, Rice, Kim, Soilihi, Hassane, de Reynies, Aurélien, Minucci, Saverio, de Thé, Hugues

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PML is a ROS sensor activating p53 upon oxidative stress von Niwa-Kawakita, Michiko, Ferhi, Omar, Soilihi, Hassane, Le Bras, Morgane, Lallemand-Breitenbach, Valérie, de Thé, Hugues

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Oxidative stress-induced assembly of PML nuclear bodies controls sumoylation of partner proteins von Sahin, Umut, Ferhi, Omar, Jeanne, Marion, Benhenda, Shirine, Berthier, Caroline, Jollivet, Florence, Niwa-Kawakita, Michiko, Faklaris, Orestis, Setterblad, Niclas, de Thé, Hugues, Lallemand-Breitenbach, Valérie

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PML IV/ARF interaction enhances p53 SUMO-1 conjugation, activation, and senescence von Ivanschitz, Lisa, Takahashi, Yuki, Jollivet, Florence, Ayrault, Olivier, Le Bras, Morgane, de Thé, Hugues

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RING tetramerization is required for nuclear body biogenesis and PML sumoylation von Wang, Pengran, Benhenda, Shirine, Wu, Haiyan, Lallemand-Breitenbach, Valérie, Zhen, Tao, Jollivet, Florence, Peres, Laurent, Li, Yuwen, Chen, Sai-Juan, Chen, Zhu, de Thé, Hugues, Meng, Guoyu

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PML/RARA oxidation and arsenic binding initiate the antileukemia response of As2O3 von Jeanne, Marion, Lallemand-Breitenbach, Valérie, Ferhi, Omar, Koken, Marcel, Le Bras, Morgane, Duffort, Stéphanie, Peres, Laurent, Berthier, Caroline, Soilihi, Hassane, Raught, Brian, de Thé, Hugues

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Characterization of a Large Panel of Patient-Derived Tumor Xenografts Representing the Clinical Heterogeneity of Human Colorectal Cancer von JULIEN, Sylvia, MERINO-TRIGO, Ana, WEISWALD, Louis-Bastien, LANTUAS, Denis, MORGAND, Loïc, PHAM, Emmanuel, GONIN, Patrick, DANGLES-MARIE, Virginie, JOB, Bastien, DESSEN, Philippe, BRUNO, Alain, PIERRE, Alain, LACROIX, Ludovic, DE THE, Hugues, SOLIMAN, Hany, NUNES, Manoel, LARDIER, Guillaume, CALVET, Loreley, DEMERS, Brigitte, PREVOST, Gregoire, VRIGNAUD, Patricia, ROMAN-ROMAN, Sergio, DUCHAMP, Olivier, POCARD, Marc, BERTHET, Cyril, GOERE, Diane, MARIANI, Pascale, LANDRON, Sophie, BIGOT, Ludovic, NEMATI, Fariba, DARTIGUES, Peggy

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Arsenic Trioxide Controls the Fate of the PML-RARα Oncoprotein by Directly Binding PML von Zhang, Xiao-Wei, Yan, Xiao-Jing, Zhou, Zi-Ren, Yang, Fei-Fei, Wu, Zi-Yu, Sun, Hong-Bin, Liang, Wen-Xue, Song, Ai-Xin, Lallemand-Breitenbach, Valerie, Jeanne, Marion, Zhang, Qun-Ye, Yang, Huai-Yu, Huang, Qiu-Hua, Zhou, Guang-Biao, Tong, Jian-Hua, Zhang, Yan, Wu, Ji-Hui, Hu, Hong-Yu, de Thé, Hugues, Chen, Sai-Juan, Chen, Zhu

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Retinoic acid and arsenic trioxide trigger degradation of mutated NPM1, resulting in apoptosis of AML cells von El Hajj, Hiba, Dassouki, Zeina, Berthier, Caroline, Raffoux, Emmanuel, Ades, Lionel, Legrand, Olivier, Hleihel, Rita, Sahin, Umut, Tawil, Nadim, Salameh, Ala, Zibara, Kazem, Darwiche, Nadine, Mohty, Mohamad, Dombret, Hervé, Fenaux, Pierre, de Thé, Hugues, Bazarbachi, Ali

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Inhibition of transcription by dactinomycin reveals a new characteristic of immunogenic cell stress von Humeau, Juliette, Sauvat, Allan, Cerrato, Giulia, Xie, Wei, Loos, Friedemann, Iannantuoni, Francesca, Bezu, Lucillia, Lévesque, Sarah, Paillet, Juliette, Pol, Jonathan, Leduc, Marion, Zitvogel, Laurence, de Thé, Hugues, Kepp, Oliver, Kroemer, Guido

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Prognostic value of TP53 gene mutations in myelodysplastic syndromes and acute myeloid leukemia treated with azacitidine von Bally, Cecile, Adès, Lionel, Renneville, Aline, Sebert, Marie, Eclache, Virginie, Preudhomme, Claude, Mozziconacci, Marie-Joelle, de The, Hugues, Lehmann-Che, Jacqueline, Fenaux, Pierre

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Interconversion between Tumorigenic and Differentiated States in Acute Myeloid Leukemia von McKenzie, Mark D., Ghisi, Margherita, Oxley, Ethan P., Ngo, Steven, Cimmino, Luisa, Esnault, Cécile, Liu, Ruijie, Salmon, Jessica M., Bell, Charles C., Ahmed, Nouraiz, Erlichster, Michael, Witkowski, Matthew T., Liu, Grace J., Chopin, Michael, Dakic, Aleksandar, Simankowicz, Emilia, Pomilio, Giovanna, Vu, Tina, Krsmanovic, Pavle, Su, Shian, Tian, Luyi, Baldwin, Tracey M., Zalcenstein, Daniela A., DiRago, Ladina, Wang, Shu, Metcalf, Donald, Johnstone, Ricky W., Croker, Ben A., Lancaster, Graeme I., Murphy, Andrew J., Naik, Shalin H., Nutt, Stephen L., Pospisil, Vitek, Schroeder, Timm, Wall, Meaghan, Dawson, Mark A., Wei, Andrew H., de Thé, Hugues, Ritchie, Matthew E., Zuber, Johannes, Dickins, Ross A.

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Exploration of nuclear body-enhanced sumoylation reveals that PML represses 2-cell features of embryonic stem cells von Tessier, Sarah, Ferhi, Omar, Geoffroy, Marie-Claude, González-Prieto, Román, Canat, Antoine, Quentin, Samuel, Pla, Marika, Niwa-Kawakita, Michiko, Bercier, Pierre, Rérolle, Domitille, Tirard, Marilyn, Therizols, Pierre, Fabre, Emmanuelle, Vertegaal, Alfred C. O., de Thé, Hugues, Lallemand-Breitenbach, Valérie

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ATL response to arsenic/interferon therapy is triggered by SUMO/PML/RNF4-dependent Tax degradation von Dassouki, Zeina, Sahin, Umut, El Hajj, Hiba, Jollivet, Florence, Kfoury, Youmna, Lallemand-Breitenbach, Valérie, Hermine, Olivier, de Thé, Hugues, Bazarbachi, Ali

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PML nuclear bodies: from architecture to function von Lallemand-Breitenbach, Valérie, de Thé, Hugues

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Dual origin of relapses in retinoic-acid resistant acute promyelocytic leukemia von Lehmann-Che, Jacqueline, Bally, Cécile, Letouzé, Eric, Berthier, Caroline, Yuan, Hao, Jollivet, Florence, Ades, Lionel, Cassinat, Bruno, Hirsch, Pierre, Pigneux, Arnaud, Mozziconacci, Marie-Joelle, Kogan, Scott, Fenaux, Pierre, de Thé, Hugues

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Exquisite sensitivity of TP53 mutant and basal breast cancers to a dose-dense epirubicin-cyclophosphamide regimen von Bertheau, Philippe, Turpin, Elisabeth, Rickman, David S, Espié, Marc, de Reyniès, Aurélien, Feugeas, Jean-Paul, Plassa, Louis-François, Soliman, Hany, Varna, Mariana, de Roquancourt, Anne, Lehmann-Che, Jacqueline, Beuzard, Yves, Marty, Michel, Misset, Jean-Louis, Janin, Anne, de Thé, Hugues

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Acute promyelocytic leukaemia: novel insights into the mechanisms of cure von de Thé, Hugues, Chen, Zhu

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Irf2bp2a regulates terminal granulopoiesis through proteasomal degradation of Gfi1aa in zebrafish von Gao, Shuo, Wang, Zixuan, Wang, Luxiang, Wang, Haihong, Yuan, Hao, Liu, Xiaohui, Chen, Saijuan, Chen, Zhu, de Thé, Hugues, Zhang, Wenqing, Zhang, Yiyue, Zhu, Jun, Zhou, Jun

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