Lgr5+ Stem Cells Are Indispensable for Radiation-Induced Intestinal Regeneration von Metcalfe, Ciara, Kljavin, Noelyn M., Ybarra, Ryan, de Sauvage, Frederic J.

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Parasitic helminths induce fetal-like reversion in the intestinal stem cell niche von Nusse, Ysbrand M., Savage, Adam K., Marangoni, Pauline, Rosendahl-Huber, Axel K. M., Landman, Tyler A., de Sauvage, Frederic J., Locksley, Richard M., Klein, Ophir D.

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Cellular Plasticity in Intestinal Homeostasis and Disease von de Sousa e Melo, Felipe, de Sauvage, Frederic J.

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Lgr5+ telocytes are a signaling source at the intestinal villus tip von Bahar Halpern, Keren, Massalha, Hassan, Zwick, Rachel K., Moor, Andreas E., Castillo-Azofeifa, David, Rozenberg, Milena, Farack, Lydia, Egozi, Adi, Miller, Dan R., Averbukh, Inna, Harnik, Yotam, Weinberg-Corem, Noa, de Sauvage, Frederic J., Amit, Ido, Klein, Ophir D., Shoshkes-Carmel, Michal, Itzkovitz, Shalev

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Opposing Activities of Notch and Wnt Signaling Regulate Intestinal Stem Cells and Gut Homeostasis von Tian, Hua, Biehs, Brian, Chiu, Cecilia, Siebel, Christian W., Wu, Yan, Costa, Mike, de Sauvage, Frederic J., Klein, Ophir D.

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Genomic Analysis of Smoothened Inhibitor Resistance in Basal Cell Carcinoma von Sharpe, Hayley J., Pau, Gregoire, Dijkgraaf, Gerrit J., Basset-Seguin, Nicole, Modrusan, Zora, Januario, Thomas, Tsui, Vickie, Durham, Alison B., Dlugosz, Andrzej A., Haverty, Peter M., Bourgon, Richard, Tang, Jean Y., Sarin, Kavita Y., Dirix, Luc, Fisher, David C., Rudin, Charles M., Sofen, Howard, Migden, Michael R., Yauch, Robert L., de Sauvage, Frederic J.

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Development of Th1-type immune responses requires the type I cytokine receptor TCCR von QI CHEN, GHILARDL, Nico, HUA WANG, BAKER, Thad, XIE, Ming-Hong, GURNEY, Austin, GREWAL, Iqbal S, DE SAUVAGE, Fredertc J

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The great escape: tumour cell plasticity in resistance to targeted therapy von Boumahdi, Soufiane, de Sauvage, Frederic J.

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Tissue regeneration: Reserve or reverse? von Shivdasani, Ramesh A, Clevers, Hans, de Sauvage, Frederic J

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A distinct role for Lgr5+ stem cells in primary and metastatic colon cancer von de Sousa e Melo, Felipe, Kurtova, Antonina V., Harnoss, Jonathan M., Kljavin, Noelyn, Hoeck, Joerg D., Hung, Jeffrey, Anderson, Jeffrey Eastham, Storm, Elaine E., Modrusan, Zora, Koeppen, Hartmut, Dijkgraaf, Gerrit J. P., Piskol, Robert, de Sauvage, Frederic J.

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Hedgehog Fights Back: Mechanisms of Acquired Resistance against Smoothened Antagonists von METCALFE, Ciara, DE SAUVAGE, Frederic J

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Mechanisms of Hedgehog pathway activation in cancer and implications for therapy von Scales, Suzie J, de Sauvage, Frederic J

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Distinct Mesenchymal Cell Populations Generate the Essential Intestinal BMP Signaling Gradient von McCarthy, Neil, Manieri, Elisa, Storm, Elaine E., Saadatpour, Assieh, Luoma, Adrienne M., Kapoor, Varun N., Madha, Shariq, Gaynor, Liam T., Cox, Christian, Keerthivasan, Shilpa, Wucherpfennig, Kai, Yuan, Guo-Cheng, de Sauvage, Frederic J., Turley, Shannon J., Shivdasani, Ramesh A.

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Oncogenic ERBB3 Mutations in Human Cancers von Jaiswal, Bijay S., Kljavin, Noelyn M., Stawiski, Eric W., Chan, Emily, Parikh, Chaitali, Durinck, Steffen, Chaudhuri, Subhra, Pujara, Kanan, Guillory, Joseph, Edgar, Kyle A., Janakiraman, Vasantharajan, Scholz, Rolf-Peter, Bowman, Krista K., Lorenzo, Maria, Li, Hong, Wu, Jiansheng, Yuan, Wenlin, Peters, Brock A., Kan, Zhengyan, Stinson, Jeremy, Mak, Michelle, Modrusan, Zora, Eigenbrot, Charles, Firestein, Ron, Stern, Howard M., Rajalingam, Krishnaraj, Schaefer, Gabriele, Merchant, Mark A., Sliwkowski, Mark X., de Sauvage, Frederic J., Seshagiri, Somasekar

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Comprehensive genomic analysis of malignant pleural mesothelioma identifies recurrent mutations, gene fusions and splicing alterations von Bueno, Raphael, Stawiski, Eric W, Goldstein, Leonard D, Durinck, Steffen, De Rienzo, Assunta, Modrusan, Zora, Gnad, Florian, Nguyen, Thong T, Jaiswal, Bijay S, Chirieac, Lucian R, Sciaranghella, Daniele, Dao, Nhien, Gustafson, Corinne E, Munir, Kiara J, Hackney, Jason A, Chaudhuri, Amitabha, Gupta, Ravi, Guillory, Joseph, Toy, Karen, Ha, Connie, Chen, Ying-Jiun, Stinson, Jeremy, Chaudhuri, Subhra, Zhang, Na, Wu, Thomas D, Sugarbaker, David J, de Sauvage, Frederic J, Richards, William G, Seshagiri, Somasekar

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Genomic analysis identifies new drivers and progression pathways in skin basal cell carcinoma von Bonilla, Ximena, Parmentier, Laurent, King, Bryan, Bezrukov, Fedor, Kaya, Gürkan, Zoete, Vincent, Seplyarskiy, Vladimir B, Sharpe, Hayley J, McKee, Thomas, Letourneau, Audrey, Ribaux, Pascale G, Popadin, Konstantin, Basset-Seguin, Nicole, Chaabene, Rouaa Ben, Santoni, Federico A, Andrianova, Maria A, Guipponi, Michel, Garieri, Marco, Verdan, Carole, Grosdemange, Kerstin, Sumara, Olga, Eilers, Martin, Aifantis, Iannis, Michielin, Olivier, de Sauvage, Frederic J, Antonarakis, Stylianos E, Nikolaev, Sergey I

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Gremlin 1+ fibroblastic niche maintains dendritic cell homeostasis in lymphoid tissues von Kapoor, Varun N., Müller, Sören, Keerthivasan, Shilpa, Brown, Markus, Chalouni, Cecile, Storm, Elaine E., Castiglioni, Alessandra, Lane, Ryan, Nitschke, Maximilian, Dominguez, Claudia X., Astarita, Jillian L., Krishnamurty, Akshay T., Carbone, Catherine B., Senbabaoglu, Yasin, Wang, Amber W., Wu, Xiumin, Cremasco, Viviana, Roose-Girma, Merone, Tam, Lucinda, Doerr, Jonas, Chen, Mark Z., Lee, Wyne P., Modrusan, Zora, Yang, Yeqing Angela, Bourgon, Richard, Sandoval, Wendy, Shaw, Andrey S., de Sauvage, Frederic J., Mellman, Ira, Moussion, Christine, Turley, Shannon J.

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Recurrent R-spondin fusions in colon cancer von Seshagiri, Somasekar, Stawiski, Eric W., Durinck, Steffen, Modrusan, Zora, Storm, Elaine E., Conboy, Caitlin B., Chaudhuri, Subhra, Guan, Yinghui, Janakiraman, Vasantharajan, Jaiswal, Bijay S., Guillory, Joseph, Ha, Connie, Dijkgraaf, Gerrit J. P., Stinson, Jeremy, Gnad, Florian, Huntley, Melanie A., Degenhardt, Jeremiah D., Haverty, Peter M., Bourgon, Richard, Wang, Weiru, Koeppen, Hartmut, Gentleman, Robert, Starr, Timothy K., Zhang, Zemin, Largaespada, David A., Wu, Thomas D., de Sauvage, Frederic J.

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Spectrum of diverse genomic alterations define non–clear cell renal carcinoma subtypes von Durinck, Steffen, Stawiski, Eric W, Pavía-Jiménez, Andrea, Modrusan, Zora, Kapur, Payal, Jaiswal, Bijay S, Zhang, Na, Toffessi-Tcheuyap, Vanina, Nguyen, Thong T, Pahuja, Kanika Bajaj, Chen, Ying-Jiun, Saleem, Sadia, Chaudhuri, Subhra, Heldens, Sherry, Jackson, Marlena, Peña-Llopis, Samuel, Guillory, Joseph, Toy, Karen, Ha, Connie, Harris, Corissa J, Holloman, Eboni, Hill, Haley M, Stinson, Jeremy, Rivers, Celina Sanchez, Janakiraman, Vasantharajan, Wang, Weiru, Kinch, Lisa N, Grishin, Nick V, Haverty, Peter M, Chow, Bernard, Gehring, Julian S, Reeder, Jens, Pau, Gregoire, Wu, Thomas D, Margulis, Vitaly, Lotan, Yair, Sagalowsky, Arthur, Pedrosa, Ivan, de Sauvage, Frederic J, Brugarolas, James, Seshagiri, Somasekar

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Influence of tumour micro-environment heterogeneity on therapeutic response von Junttila, Melissa R., de Sauvage, Frederic J.

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