IRDiRC Drug Repurposing Guidebook: making better use of existing drugs to tackle rare diseases von Hechtelt Jonker, Anneliene, Day, Simon, Gabaldo, Michela, Stone, Heather, de Kort, Martin, O’Connor, Daniel J., Pasmooij, Anna Maria Gerdina

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Drug repurposing for rare: progress and opportunities for the rare disease community von Jonker, Anneliene Hechtelt, O'Connor, Daniel, Cavaller-Bellaubi, Maria, Fetro, Christine, Gogou, Maria, 't Hoen, Peter A C, de Kort, Martin, Stone, Heather, Valentine, Nivedita, Pasmooij, Anna Maria Gerdina

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Conjugation of ATIII-Binding Pentasaccharides to Extend the Half-Life of Proteins: Long-Acting Insulin von de Kort, Martin, Gianotten, Bas, Wisse, Jeffry A. J., Bos, Ebo S., Eppink, Michel H. M., Mattaar, Ellen, Vogel, Gerard M. T., Dokter, Wim H. A., Honing, Maarten, Vonsovic, Stanislava, Smit, Martin-Jan, Wijkmans, Jac C. H. M., van Boeckel, Constant A. A.

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Synthesis and Evaluation of a Series of Long-Acting Glucagon-Like Peptide-1 (GLP-1) Pentasaccharide Conjugates for the Treatment of Type 2 Diabetes von Irwin, Nigel, Patterson, Steven, de Kort, Martin, Moffett, R. Charlotte, Wisse, Jeffry A. J., Dokter, Wim H. A., Bos, Ebo S., Miltenburg, André M. M., Flatt, Peter R.

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From heparin to EP217609: The long way to a new pentasaccharide-based neutralisable anticoagulant with an unprecedented pharmacological profile von Petitou, Maurice, Nancy-Portebois, Vanessa, Dubreucq, Guy, Motte, Vincent, Meuleman, Dick, de Kort, Martin, van Boeckel, Constant A. A., Vogel, Gerard M. T., Wisse, Jeffry A. J.

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Half‐life prolongation of therapeutic proteins by conjugation to ATIII‐binding pentasaccharides: a first‐in‐human study of CarboCarrier® insulin von Miltenburg, André M. M., Prohn, Marita, Kuijk, Jacqueline H. M., Tiessen, Renger G., Kort, Martin, Berg, Rob J. W.

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In Search of System‐Wide Productivity Gains ‐ The Role of Global Collaborations in Preclinical Translation von Ussi, Anton E., Kort, Martin, Coussens, Nathan P., Aittokallio, Tero, Hajduch, Marian

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Synthetic heparin derivatives as new anticoagulant drugs von de Kort, Martin, Buijsman, Rogier C., van Boeckel, Constant A.A.

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Spirophostins: Conformationally Restricted Analogues of Adenophostin A von de Kort, Martin, Regenbogen, Anouk D., Valentijn, A. Rob P. M., Challiss, R. A. John, Iwata, Yoriko, Miyamoto, Shuichi, van der Marel, Gijs A., van Boom, Jacques H.

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Synthesis and Evaluation of a Series of Long-Acting Glucagon-Like Peptide-1 (GLP-1) Pentasaccharide Conjugates for the Treatment of Type2 Diabetes von Irwin, Nigel, Patterson, Steven, deKort, Martin, Moffett, R Charlotte, Wisse, Jeffry A J, Dokter, Wim H A, Bos, Ebo S, Miltenburg, André M M, Flatt, Peter R

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Half‐life prolongation of therapeutic proteins by conjugation to ATIII ‐binding pentasaccharides: a first‐in‐human study of C arbo C arrier ® insulin von Miltenburg, André M. M., Prohn, Marita, van Kuijk, Jacqueline H. M., Tiessen, Renger G., de Kort, Martin, Berg, Rob J. W.

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Development of a novel ionic support and its application in the ionic liquid phase assisted synthesis of a potent antithrombotic von de Kort, Martin, Tuin, Adriaan W., Kuiper, Suzanne, Overkleeft, Hermen S., van der Marel, Gijs A., Buijsman, Rogier C.

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modified base J is the target for a novel DNA-binding protein in kinetoplastid protozoans von Cross, M, Kieft, R, Sabatini, R, Wilm, M, Kort, M. de, Marel, G.A. van der, Boom, J.H. van, Leeuwen, F. van, Borst, P

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Chemical and Enzymatic Synthesis of DNA Fragments Containing 5-(β-D-Glucopyranosyloxymethyl)-2′-deoxycytidine − a Modified Nucleoside in T4 Phage DNA von de Kort, Martin, de Visser, Peter C., Kurzeck, Jürgen, Meeuwenoord, Nico J., van der Marel, Gijs A., Rüger, Wolfgang, van Boom, Jacques H.

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A Versatile Approach Towards Regioselective Platinated DNA Sequences von Heetebrij, Robert J., de Kort, Martin, Meeuwenoord, Nico J., den Dulk, Hans, van der Marel, Gijs A., van Boom, Jacques H., Reedijk, Jan

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Synthesis of Oligodeoxynucleotides Containing 5-(β-D-Glucopyranosyloxymethyl)-2′-deoxyuridine, a Modified Nucleoside in the DNA of Trypanosoma Brucei von de Kort, Martin, Ebrahimi, Edwin, Wijsman, Eric R., van der Marel, Gijs A., van Boom, Jacques H.

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Synthesis and Biological Evaluation of Cyclophostin: A 5′,6″-Tethered Analog of Adenophostin A von de Kort, Martin, Regenbogen, Anouk D., Overkleeft, Herman S., John Challiss, R.A., Iwata, Yoriko, Miyamoto, Shuichi, van der Marel, Gijs A., van Boom, Jacques H.

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Synthesis of Photoaffinity Derivatives of Adenophostin A von de Kort, Martin, Luijendijk, Jaco, van der Marel, Gijs A., van Boom, Jacques H.

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Synthesis of Potent Agonists of the d-myo-Inositol 1,4,5-Trisphosphate Receptor Based on Clustered Disaccharide Polyphosphate Analogues of Adenophostin A von DE KORT, Martin, CORREA, Vanessa, VALENTIJN, A. Rob P. M., VAN DER MAREL, Gijs A., POTTER, Barry V. L., TAYLOR, Colin W., VAN BOOM, Jacques H.

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Antitrombotiske dobbelt inhibitorer omfattende en biotin-rest von KORT MARTIN DE, BOECKEL CONSTANT ADRIAAN ANTON VAN

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