Hallmarks of ribosomopathies von Kampen, Kim R, Sulima, Sergey O, Vereecke, Stijn, De Keersmaecker, Kim

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The ribosomal protein gene RPL5 is a haploinsufficient tumor suppressor in multiple cancer types von Fancello, Laura, Kampen, Kim R, Hofman, Isabel J F, Verbeeck, Jelle, De Keersmaecker, Kim

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Translatome analysis reveals altered serine and glycine metabolism in T-cell acute lymphoblastic leukemia cells von Kampen, Kim R., Fancello, Laura, Girardi, Tiziana, Rinaldi, Gianmarco, Planque, Mélanie, Sulima, Sergey O., Loayza-Puch, Fabricio, Verbelen, Benno, Vereecke, Stijn, Verbeeck, Jelle, Op de Beeck, Joyce, Royaert, Jonathan, Vermeersch, Pieter, Cassiman, David, Cools, Jan, Agami, Reuven, Fiers, Mark, Fendt, Sarah-Maria, De Keersmaecker, Kim

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Bypass of the pre-60S ribosomal quality control as a pathway to oncogenesis von Sulima, Sergey O., Patchett, Stephanie, Advani, Vivek M., De Keersmaecker, Kim, Johnson, Arlen W., Dinman, Jonathan D.

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Optimizing the diagnostic workflow for acute lymphoblastic leukemia by optical genome mapping von Rack, Katrina, Bie, Jolien, Ameye, Geneviève, Gielen, Olga, Demeyer, Sofie, Cools, Jan, Keersmaecker, Kim, Vermeesch, Joris R., Maertens, Johan, Segers, Heidi, Michaux, Lucienne, Dewaele, Barbara

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The ins and outs of serine and glycine metabolism in cancer von Geeraerts, Shauni L., Heylen, Elien, De Keersmaecker, Kim, Kampen, Kim R.

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Single-cell sequencing reveals the origin and the order of mutation acquisition in T-cell acute lymphoblastic leukemia von De Bie, Jolien, Demeyer, Sofie, Alberti-Servera, Llucia, Geerdens, Ellen, Segers, Heidi, Broux, Michaël, De Keersmaecker, Kim, Michaux, Lucienne, Vandenberghe, Peter, Voet, Thierry, Boeckx, Nancy, Uyttebroeck, Anne, Cools, Jan

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Exome sequencing identifies mutation in CNOT3 and ribosomal genes RPL5 and RPL10 in T-cell acute lymphoblastic leukemia von De Keersmaecker, Kim, Atak, Zeynep Kalender, Li, Ning, Vicente, Carmen, Patchett, Stephanie, Girardi, Tiziana, Gianfelici, Valentina, Geerdens, Ellen, Clappier, Emmanuelle, Porcu, Michaël, Lahortiga, Idoya, Lucà, Rossella, Yan, Jiekun, Hulselmans, Gert, Vranckx, Hilde, Vandepoel, Roel, Sweron, Bram, Jacobs, Kris, Mentens, Nicole, Wlodarska, Iwona, Cauwelier, Barbara, Cloos, Jacqueline, Soulier, Jean, Uyttebroeck, Anne, Bagni, Claudia, Hassan, Bassem A, Vandenberghe, Peter, Johnson, Arlen W, Aerts, Stein, Cools, Jan

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Ribosomopathies and the paradox of cellular hypo- to hyperproliferation von De Keersmaecker, Kim, Sulima, Sergey O., Dinman, Jonathan D.

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Genetic inactivation of the polycomb repressive complex 2 in T cell acute lymphoblastic leukemia von Ntziachristos, Panagiotis, Tsirigos, Aristotelis, Vlierberghe, Pieter Van, Nedjic, Jelena, Trimarchi, Thomas, Flaherty, Maria Sol, Ferres-Marco, Dolors, da Ros, Vanina, Tang, Zuojian, Siegle, Jasmin, Asp, Patrik, Hadler, Michael, Rigo, Isaura, Keersmaecker, Kim De, Patel, Jay, Huynh, Tien, Utro, Filippo, Poglio, Sandrine, Samon, Jeremy B, Paietta, Elisabeth, Racevskis, Janis, Rowe, Jacob M, Rabadan, Raul, Levine, Ross L, Brown, Stuart, Pflumio, Francoise, Dominguez, Maria, Ferrando, Adolfo, Aifantis, Iannis

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Repurposing the Antidepressant Sertraline as SHMT Inhibitor to Suppress Serine/Glycine Synthesis-Addicted Breast Tumor Growth von Geeraerts, Shauni Lien, Kampen, Kim Rosalie, Rinaldi, Gianmarco, Gupta, Purvi, Planque, Mélanie, Louros, Nikolaos, Heylen, Elien, De Cremer, Kaat, De Brucker, Katrijn, Vereecke, Stijn, Verbelen, Benno, Vermeersch, Pieter, Schymkowitz, Joost, Rousseau, Frederic, Cassiman, David, Fendt, Sarah-Maria, Voet, Arnout, Cammue, Bruno P A, Thevissen, Karin, De Keersmaecker, Kim

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The ribosomal RPL10 R98S mutation drives IRES-dependent BCL-2 translation in T-ALL von Kampen, Kim R., Sulima, Sergey O., Verbelen, Benno, Girardi, Tiziana, Vereecke, Stijn, Rinaldi, Gianmarco, Verbeeck, Jelle, Op de Beeck, Joyce, Uyttebroeck, Anne, Meijerink, Jules P. P., Moorman, Anthony V., Harrison, Christine J., Spincemaille, Pieter, Cools, Jan, Cassiman, David, Fendt, Sarah-Maria, Vermeersch, Pieter, De Keersmaecker, Kim

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Cancer Biogenesis in Ribosomopathies von Sulima, Sergey O, Kampen, Kim R, De Keersmaecker, Kim

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A novel mouse model provides insights into the neutropenia associated with the ribosomopathy Shwachman-Diamond syndrome von De Keersmaecker, Kim

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Ribosomal Lesions Promote Oncogenic Mutagenesis von Sulima, Sergey O, Kampen, Kim R, Vereecke, Stijn, Pepe, Daniele, Fancello, Laura, Verbeeck, Jelle, Dinman, Jonathan D, De Keersmaecker, Kim

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Comprehensive analysis of transcriptome variation uncovers known and novel driver events in T-cell acute lymphoblastic leukemia von Atak, Zeynep Kalender, Gianfelici, Valentina, Hulselmans, Gert, De Keersmaecker, Kim, Devasia, Arun George, Geerdens, Ellen, Mentens, Nicole, Chiaretti, Sabina, Durinck, Kaat, Uyttebroeck, Anne, Vandenberghe, Peter, Wlodarska, Iwona, Cloos, Jacqueline, Foà, Robin, Speleman, Frank, Cools, Jan, Aerts, Stein

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Reverse engineering of TLX oncogenic transcriptional networks identifies RUNX1 as tumor suppressor in T-ALL von Della Gatta, Giusy, Palomero, Teresa, Perez-Garcia, Arianne, Ambesi-Impiombato, Alberto, Bansal, Mukesh, Carpenter, Zachary W, De Keersmaecker, Kim, Sole, Xavier, Xu, Luyao, Paietta, Elisabeth, Racevskis, Janis, Wiernik, Peter H, Rowe, Jacob M, Meijerink, Jules P, Califano, Andrea, Ferrando, Adolfo A

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Carfilzomib-induced reticulocytosis in patients with multiple myeloma is caused by impaired terminal erythroid maturation von Kint, Nicolas G., Heylen, Elien, Pepe, Daniele, De Keersmaecker, Kim, Verfaillie, Catherine M., Delforge, Michel

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Rise of the specialized onco-ribosomes von Kampen, Kim R, Sulima, Sergey O, De Keersmaecker, Kim

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T-ALL: ALL a matter of Translation? von Girardi, Tiziana, De Keersmaecker, Kim

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