Fluorescein-based sensors to purify human α-cells for functional and transcriptomic analyses von Kahraman, Sevim, Shibue, Kimitaka, De Jesus, Dario F, Kim, Hyunki, Hu, Jiang, Manna, Debasish, Wagner, Bridget, Choudhary, Amit, Kulkarni, Rohit N

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RADAR: differential analysis of MeRIP-seq data with a random effect model von Zhang, Zijie, Zhan, Qi, Eckert, Mark, Zhu, Allen, Chryplewicz, Agnieszka, De Jesus, Dario F, Ren, Decheng, Kulkarni, Rohit N, Lengyel, Ernst, He, Chuan, Chen, Mengjie

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Luseogliflozin increases beta cell proliferation through humoral factors that activate an insulin receptor- and IGF-1 receptor-independent pathway von Shirakawa, Jun, Tajima, Kazuki, Okuyama, Tomoko, Kyohara, Mayu, Togashi, Yu, De Jesus, Dario F., Basile, Giorgio, Kin, Tatsuya, Shapiro, A. M. James, Kulkarni, Rohit N., Terauchi, Yasuo

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SUCNR1 regulates insulin secretion and glucose elevates the succinate response in people with prediabetes von Sabadell-Basallote, Joan, Astiarraga, Brenno, Castaño, Carlos, Ejarque, Miriam, Repollés-de-Dalmau, Maria, Quesada, Ivan, Blanco, Jordi, Nuñez-Roa, Catalina, Rodríguez-Peña, M-Mar, Martínez, Laia, De Jesus, Dario F, Marroqui, Laura, Bosch, Ramon, Montanya, Eduard, Sureda, Francesc X, Tura, Andrea, Mari, Andrea, Kulkarni, Rohit N, Vendrell, Joan, Fernández-Veledo, Sonia

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Secreted EMC10 is upregulated in human obesity and its neutralizing antibody prevents diet-induced obesity in mice von Wang, Xuanchun, Li, Yanliang, Qiang, Guifen, Wang, Kaihua, Dai, Jiarong, McCann, Maximilian, Munoz, Marcos D., Gil, Victoria, Yu, Yifei, Li, Shengxian, Yang, Zhihong, Xu, Shanshan, Cordoba-Chacon, Jose, De Jesus, Dario F., Sun, Bei, Chen, Kuangyang, Wang, Yahao, Liu, Xiaoxia, Miao, Qing, Zhou, Linuo, Hu, Renming, Ding, Qiang, Kulkarni, Rohit N., Gao, Daming, Blüher, Matthias, Liew, Chong Wee

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E2F1 transcription factor mediates a link between fat and islets to promote β cell proliferation in response to acute insulin resistance von Shirakawa, Jun, Togashi, Yu, Basile, Giorgio, Okuyama, Tomoko, Inoue, Ryota, Fernandez, Megan, Kyohara, Mayu, De Jesus, Dario F., Goto, Nozomi, Zhang, Wei, Tsuno, Takahiro, Kin, Tatsuya, Pan, Hui, Dreyfuss, Jonathan M., Shapiro, A.M. James, Yi, Peng, Terauchi, Yasuo, Kulkarni, Rohit N.

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“Omics” and “epi-omics” underlying the β-cell adaptation to insulin resistance von De Jesus, Dario F., Kulkarni, Rohit N.

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Excessive Cellular Proliferation Negatively Impacts Reprogramming Efficiency of Human Fibroblasts von Gupta, Manoj K., Teo, Adrian Kee Keong, Rao, Tata Nageswara, Bhatt, Shweta, Kleinridders, Andre, Shirakawa, Jun, Takatani, Tomozumi, Hu, Jiang, De Jesus, Dario F., Windmueller, Rebecca, Wagers, Amy J., Kulkarni, Rohit N.

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Insulin receptor-mediated signaling regulates pluripotency markers and lineage differentiation von Gupta, Manoj K., De Jesus, Dario F., Kahraman, Sevim, Valdez, Ivan A., Shamsi, Farnaz, Yi, Lian, Swensen, Adam C., Tseng, Yu-Hua, Qian, Wei-Jun, Kulkarni, Rohit N.

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NREP contributes to development of NAFLD by regulating one-carbon metabolism in primary human hepatocytes von De Jesus, Dario F., Kimura, Tomohiko, Gupta, Manoj K., Kulkarni, Rohit N.

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m6A mRNA methylation by METTL14 regulates early pancreatic cell differentiation von Kahraman, Sevim, De Jesus, Dario F, Wei, Jiangbo, Brown, Natalie K, Zou, Zhongyu, Hu, Jiang, Pirouz, Mehdi, Gregory, Richard I, He, Chuan, Kulkarni, Rohit N

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SerpinB1 Promotes Pancreatic β Cell Proliferation von El Ouaamari, Abdelfattah, Dirice, Ercument, Gedeon, Nicholas, Hu, Jiang, Zhou, Jian-Ying, Shirakawa, Jun, Hou, Lifei, Goodman, Jessica, Karampelias, Christos, Qiang, Guifeng, Boucher, Jeremie, Martinez, Rachael, Gritsenko, Marina A., De Jesus, Dario F., Kahraman, Sevim, Bhatt, Shweta, Smith, Richard D., Beer, Hans-Dietmar, Jungtrakoon, Prapaporn, Gong, Yanping, Goldfine, Allison B., Liew, Chong Wee, Doria, Alessandro, Andersson, Olov, Qian, Wei-Jun, Remold-O’Donnell, Eileen, Kulkarni, Rohit N.

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Parental metabolic syndrome epigenetically reprograms offspring hepatic lipid metabolism in mice von De Jesus, Dario F., Orime, Kazuki, Kaminska, Dorota, Kimura, Tomohiko, Basile, Giorgio, Wang, Chih-Hao, Haertle, Larissa, Riemens, Renzo, Brown, Natalie K., Hu, Jiang, Mannisto, Ville, Silva, Amelia M., Dirice, Ercument, Tseng, Yu-Hua, Haaf, Thomas, Pihlajamaki, Jussi, Kulkarni, Rohit N.

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Epigenetic modifiers of islet function and mass von De Jesus, Dario F, Kulkarni, Rohit N

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m6A mRNA methylation in brown fat regulates systemic insulin sensitivity via an inter-organ prostaglandin signaling axis independent of UCP1 von Xiao, Ling, De Jesus, Dario F., Ju, Cheng-Wei, Wei, Jiang Bo, Hu, Jiang, DiStefano-Forti, Ava, Tsuji, Tadataka, Cero, Cheryl, Männistö, Ville, Manninen, Suvi M., Wei, Siying, Ijaduola, Oluwaseun, Blüher, Matthias, Cypess, Aaron M., Pihlajamäki, Jussi, Tseng, Yu-Hua, He, Chuan, Kulkarni, Rohit N.

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A MAFG-lncRNA axis links systemic nutrient abundance to hepatic glucose metabolism von Pradas-Juni, Marta, Hansmeier, Nils R., Link, Jenny C., Schmidt, Elena, Larsen, Bjørk Ditlev, Klemm, Paul, Meola, Nicola, Topel, Hande, Loureiro, Rute, Dhaouadi, Ines, Kiefer, Christoph A., Schwarzer, Robin, Khani, Sajjad, Oliverio, Matteo, Awazawa, Motoharu, Frommolt, Peter, Heeren, Joerg, Scheja, Ludger, Heine, Markus, Dieterich, Christoph, Büning, Hildegard, Yang, Ling, Cao, Haiming, Jesus, Dario F. De, Kulkarni, Rohit N., Zevnik, Branko, Tröder, Simon E., Knippschild, Uwe, Edwards, Peter A., Lee, Richard G., Yamamoto, Masayuki, Ulitsky, Igor, Fernandez-Rebollo, Eduardo, Vallim, Thomas Q. de Aguiar, Kornfeld, Jan-Wilhelm

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Redox regulation of m6A methyltransferase METTL3 in β-cells controls the innate immune response in type 1 diabetes von De Jesus, Dario F., Zhang, Zijie, Brown, Natalie K., Li, Xiaolu, Xiao, Ling, Hu, Jiang, Gaffrey, Matthew J., Fogarty, Garrett, Kahraman, Sevim, Wei, Jiangbo, Basile, Giorgio, Rana, Tariq M., Mathews, Clayton, Powers, Alvin C., Parent, Audrey V., Atkinson, Mark A., Dhe-Paganon, Sirano, Eizirik, Decio L., Qian, Wei-Jun, He, Chuan, Kulkarni, Rohit N.

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Maternal insulin resistance and transient hyperglycemia impact the metabolic and endocrine phenotypes of offspring von Kahraman, Sevim, Dirice, Ercument, De Jesus, Dario F, Hu, Jiang, Kulkarni, Rohit N

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Deficiency of the metabolic enzyme SCHAD in pancreatic β-cells promotes amino acid–sensitive hypoglycemia von St-Louis, Johanna L., El Jellas, Khadija, Velasco, Kelly, Slipp, Brittany A., Hu, Jiang, Helgeland, Geir, Steine, Solrun J., De Jesus, Dario F., Kulkarni, Rohit N., Molven, Anders

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Excess pancreatic elastase alters acinar-β cell communication by impairing the mechano-signaling and the PAR2 pathways von Basile, Giorgio, Vetere, Amedeo, Hu, Jiang, Ijaduola, Oluwaseun, Zhang, Yi, Liu, Ka-Cheuk, Eltony, Amira M., De Jesus, Dario F., Fukuda, Kazuki, Doherty, Grace, Leech, Colin A., Chepurny, Oleg G., Holz, George G., Yun, Seok-Hyun, Andersson, Olov, Choudhary, Amit, Wagner, Bridget K., Kulkarni, Rohit N.

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