2-Aminothiazole as a Novel Kinase Inhibitor Template. Structure−Activity Relationship Studies toward the Discovery of N-(2-Chloro-6-methylphenyl)-2-[[6-[4-(2-hydroxyethyl)-1- piper... von Das, Jagabandhu, Chen, Ping, Norris, Derek, Padmanabha, Ramesh, Lin, James, Moquin, Robert V, Shen, Zhongqi, Cook, Lynda S, Doweyko, Arthur M, Pitt, Sidney, Pang, Suhong, Shen, Ding Ren, Fang, Qiong, de Fex, Henry F, McIntyre, Kim W, Shuster, David J, Gillooly, Kathleen M, Behnia, Kamelia, Schieven, Gary L, Wityak, John, Barrish, Joel C

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Discovery and initial SAR of 2-amino-5-carboxamidothiazoles as inhibitors of the Src-family kinase p56(Lck) von Wityak, John, Das, Jagabandhu, Moquin, Robert V, Shen, Zhongqi, Lin, James, Chen, Ping, Doweyko, Arthur M, Pitt, Sidney, Pang, Suhong, Shen, Ding Ren, Fang, Qiong, de Fex, Henry F, Schieven, Gary L, Kanner, Steven B, Barrish, Joel C

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Discovery of novel 2-(aminoheteroaryl)-thiazole-5-carboxamides as potent and orally active Src-family kinase p56(Lck) inhibitors von Chen, Ping, Norris, Derek, Das, Jagabandhu, Spergel, Steven H, Wityak, John, Leith, Leslie, Zhao, Rulin, Chen, Bang-Chi, Pitt, Sidney, Pang, Suhong, Shen, Ding Ren, Zhang, Rosemary, De Fex, Henry F, Doweyko, Arthur M, McIntyre, Kim W, Shuster, David J, Behnia, Kamelia, Schieven, Gary L, Barrish, Joel C

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Discovery and initial SAR of imidazoquinoxalines as inhibitors of the Src-family kinase p56(Lck) von Chen, Ping, Norris, Derek, Iwanowicz, Edwin J, Spergel, Steven H, Lin, James, Gu, Henry H, Shen, Zhongqi, Wityak, John, Lin, Tai-An, Pang, Suhong, De Fex, Henry F, Pitt, Sidney, Shen, Ding Ren, Doweyko, Arthur M, Bassolino, Donna A, Roberge, Jacques Y, Poss, Michael A, Chen, Bang-Chi, Schieven, Gary L, Barrish, Joel C

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Discovery and initial SAR of imidazoquinoxalines as inhibitors of the Src-family kinase p56Lck von PING CHEN, NORRIS, Derek, DE FEX, Henry F, PITT, Sidney, DING REN SHEN, DOWEYKO, Arthur M, BASSOLINO, Donna A, ROBERGE, Jacques Y, POSS, Michael A, CHEN, Bang-Chi, SCHIEVEN, Gary L, BARRISH, Joel C, IWANOWICZ, Edwin J, SPERGEL, Steven H, LIN, James, GU, Henry H, ZHONGQI SHEN, WITYAK, John, LIN, Tai-An, SUHONG PANG

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Discovery of novel 2-(aminoheteroaryl)-thiazole-5-carboxamides as potent and orally active Src-family kinase p56Lck inhibitors von PING CHEN, NORRIS, Derek, DING REN SHEN, ZHANG, Rosemary, DE FEX, Henry F, DOWEYKO, Arthur M, MCINTYRE, Kim W, SHUSTER, David J, BEHNIA, Kamelia, SCHIEVEN, Gary L, BARRISH, Joel C, DAS, Jagabandhu, SPERGEL, Steven H, WITYAK, John, LEITH, Leslie, RULIN ZHAO, CHEN, Bang-Chi, PITT, Sidney, SUHONG PANG

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Discovery and initial SAR of 2-amino-5-carboxamidothiazoles as inhibitors of the Src-family kinase p56Lck von WITYAK, John, DAS, Jagabandhu, QIONG FANG, DE FEX, Henry F, SCHIEVEN, Gary L, KANNER, Steven B, BARRISH, Joel C, MOQUIN, Robert V, ZHONGQI SHEN, LIN, James, PING CHEN, DOWEYKO, Arthur M, PITT, Sidney, SUHONG PANG, DING REN SHEN

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Discovery of novel 2-(aminoheteroaryl)-thiazole-5-carboxamides as potent and orally active Src-family kinase p56 Lck inhibitors von Chen, Ping, Norris, Derek, Das, Jagabandhu, Spergel, Steven H., Wityak, John, Leith, Leslie, Zhao, Rulin, Chen, Bang-Chi, Pitt, Sidney, Pang, Suhong, Shen, Ding Ren, Zhang, Rosemary, De Fex, Henry F., Doweyko, Arthur M., McIntyre, Kim W., Shuster, David J., Behnia, Kamelia, Schieven, Gary L., Barrish, Joel C.

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Discovery and initial SAR of 2-amino-5-carboxamidothiazoles as inhibitors of the Src-family kinase p56 Lck von Wityak, John, Das, Jagabandhu, Moquin, Robert V., Shen, Zhongqi, Lin, James, Chen, Ping, Doweyko, Arthur M., Pitt, Sidney, Pang, Suhong, Shen, Ding Ren, Fang, Qiong, de Fex, Henry F., Schieven, Gary L., Kanner, Steven B., Barrish, Joel C.

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Discovery and initial SAR of imidazoquinoxalines as inhibitors of the Src-family kinase p56 Lck von Chen, Ping, Norris, Derek, Iwanowicz, Edwin J., Spergel, Steven H., Lin, James, Gu, Henry H., Shen, Zhongqi, Wityak, John, Lin, Tai-An, Pang, Suhong, De Fex, Henry F., Pitt, Sidney, Shen, Ding Ren, Doweyko, Arthur M., Bassolino, Donna A., Roberge, Jacques Y., Poss, Michael A., Chen, Bang-Chi, Schieven, Gary L., Barrish, Joel C.

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