DNA Methylation Profiling for Diagnosing Undifferentiated Sarcoma with Capicua Transcriptional Receptor ( CIC ) Alterations von Miele, Evelina, De Vito, Rita, Ciolfi, Andrea, Pedace, Lucia, Russo, Ida, De Pasquale, Maria Debora, Di Giannatale, Angela, Crocoli, Alessandro, Angelis, Biagio De, Tartaglia, Marco, Alaggio, Rita, Milano, Giuseppe Maria

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ADAR1 is a new target of METTL3 and plays a pro-oncogenic role in glioblastoma by an editing-independent mechanism von Tassinari, Valentina, Cesarini, Valeriana, Tomaselli, Sara, Ianniello, Zaira, Silvestris, Domenico Alessandro, Ginistrelli, Lavinia Ceci, Martini, Maurizio, De Angelis, Biagio, De Luca, Gabriele, Vitiani, Lucia Ricci, Fatica, Alessandro, Locatelli, Franco, Gallo, Angela

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Human CAR NK Cells: A New Non-viral Method Allowing High Efficient Transfection and Strong Tumor Cell Killing von Ingegnere, Tiziano, Mariotti, Francesca Romana, Pelosi, Andrea, Quintarelli, Concetta, De Angelis, Biagio, Tumino, Nicola, Besi, Francesca, Cantoni, Claudia, Locatelli, Franco, Vacca, Paola, Moretta, Lorenzo

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Adoptive Immunotherapy Using PRAME-Specific T Cells in Medulloblastoma von Orlando, Domenico, Miele, Evelina, De Angelis, Biagio, Guercio, Marika, Boffa, Iolanda, Sinibaldi, Matilde, Po, Agnese, Caruana, Ignazio, Abballe, Luana, Carai, Andrea, Caruso, Simona, Camera, Antonio, Moseley, Annemarie, Hagedoorn, Renate S, Heemskerk, Mirjam H M, Giangaspero, Felice, Mastronuzzi, Angela, Ferretti, Elisabetta, Locatelli, Franco, Quintarelli, Concetta

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Choice of costimulatory domains and of cytokines determines CAR T-cell activity in neuroblastoma von Quintarelli, Concetta, Orlando, Domenico, Boffa, Iolanda, Guercio, Marika, Polito, Vinicia Assunta, Petretto, Andrea, Lavarello, Chiara, Sinibaldi, Matilde, Weber, Gerrit, Del Bufalo, Francesca, Giorda, Ezio, Scarsella, Marco, Petrini, Stefania, Pagliara, Daria, Locatelli, Franco, De Angelis, Biagio, Caruana, Ignazio

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Neutralizing IFNγ improves safety without compromising efficacy of CAR-T cell therapy in B-cell malignancies von Manni, Simona, Del Bufalo, Francesca, Merli, Pietro, Silvestris, Domenico Alessandro, Guercio, Marika, Caruso, Simona, Reddel, Sofia, Iaffaldano, Laura, Pezzella, Michele, Di Cecca, Stefano, Sinibaldi, Matilde, Ottaviani, Alessio, Quadraccia, Maria Cecilia, Aurigemma, Mariasole, Sarcinelli, Andrea, Ciccone, Roselia, Abbaszadeh, Zeinab, Ceccarelli, Manuela, De Vito, Rita, Lodi, Maria Chiara, Cefalo, Maria Giuseppina, Mastronuzzi, Angela, De Angelis, Biagio, Locatelli, Franco, Quintarelli, Concetta

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Polymorphonuclear myeloid-derived suppressor cells impair the anti-tumor efficacy of GD2.CAR T-cells in patients with neuroblastoma von Tumino, Nicola, Weber, Gerrit, Besi, Francesca, Del Bufalo, Francesca, Bertaina, Valentina, Paci, Paola, Quatrini, Linda, Antonucci, Laura, Sinibaldi, Matilde, Quintarelli, Concetta, Maggi, Enrico, De Angelis, Biagio, Locatelli, Franco, Moretta, Lorenzo, Vacca, Paola, Caruana, Ignazio

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CD28.OX40 co-stimulatory combination is associated with long in vivo persistence and high activity of CAR.CD30 T-cells von Guercio, Marika, Orlando, Domenico, Di Cecca, Stefano, Sinibaldi, Matilde, Boffa, Iolanda, Caruso, Simona, Abbaszadeh, Zeinab, Camera, Antonio, Cembrola, Biancamaria, Bovetti, Katia, Manni, Simona, Caruana, Ignazio, Ciccone, Roselia, Del Bufalo, Francesca, Merli, Pietro, Vinti, Luciana, Girardi, Katia, Ruggeri, Annalisa, De Stefanis, Cristiano, Pezzullo, Marco, Giorda, Ezio, Scarsella, Marco, De Vito, Rita, Barresi, Sabina, Ciolfi, Andrea, Tartaglia, Marco, Moretta, Lorenzo, Locatelli, Franco, Quintarelli, Concetta, De Angelis, Biagio

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Safe and effective off-the-shelf immunotherapy based on CAR.CD123-NK cells for the treatment of acute myeloid leukaemia von Caruso, Simona, De Angelis, Biagio, Del Bufalo, Francesca, Ciccone, Roselia, Donsante, Samantha, Volpe, Gabriele, Manni, Simona, Guercio, Marika, Pezzella, Michele, Iaffaldano, Laura, Silvestris, Domenico Alessandro, Sinibaldi, Matilde, Di Cecca, Stefano, Pitisci, Angela, Velardi, Enrico, Merli, Pietro, Algeri, Mattia, Lodi, Mariachiara, Paganelli, Valeria, Serafini, Marta, Riminucci, Mara, Locatelli, Franco, Quintarelli, Concetta

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Targeting cancer stem cells in medulloblastoma by inhibiting AMBRA1 dual function in autophagy and STAT3 signalling von Nazio, Francesca, Po, Agnese, Abballe, Luana, Ballabio, Claudio, Diomedi Camassei, Francesca, Bordi, Matteo, Camera, Antonio, Caruso, Simona, Caruana, Ignazio, Pezzullo, Marco, Ferraina, Caterina, Milletti, Giacomo, Gianesello, Matteo, Reddel, Sofia, De Luca, Carmen Dolores, Ceglie, Donatella, Marinelli, Sara, Campello, Silvia, Papaleo, Elena, Miele, Evelina, Cacchione, Antonella, Carai, Andrea, Vinci, Maria, Velardi, Enrico, De Angelis, Biagio, Tiberi, Luca, Quintarelli, Concetta, Mastronuzzi, Angela, Ferretti, Elisabetta, Locatelli, Franco, Cecconi, Francesco

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Bevacizumab-mediated tumor vasculature remodelling improves tumor infiltration and antitumor efficacy of GD2-CAR T cells in a human neuroblastoma preclinical model von Bocca, Paola, Di Carlo, Emma, Caruana, Ignazio, Emionite, Laura, Cilli, Michele, De Angelis, Biagio, Quintarelli, Concetta, Pezzolo, Annalisa, Raffaghello, Lizzia, Morandi, Fabio, Locatelli, Franco, Pistoia, Vito, Prigione, Ignazia

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PD‐1‐induced T cell exhaustion is controlled by a Drp1‐dependent mechanism von Simula, Luca, Antonucci, Ylenia, Scarpelli, Giorgia, Cancila, Valeria, Colamatteo, Alessandra, Manni, Simona, De Angelis, Biagio, Quintarelli, Concetta, Procaccini, Claudio, Matarese, Giuseppe, Tripodo, Claudio, Campello, Silvia

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CDK9 as a Valuable Target in Cancer: From Natural Compounds Inhibitors to Current Treatment in Pediatric Soft Tissue Sarcomas von Cassandri, Matteo, Fioravanti, Rossella, Pomella, Silvia, Valente, Sergio, Rotili, Dante, Del Baldo, Giada, De Angelis, Biagio, Rota, Rossella, Mai, Antonello

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Inclusion of the Inducible Caspase 9 Suicide Gene in CAR Construct Increases Safety of CAR.CD19 T Cell Therapy in B-Cell Malignancies von Guercio, Marika, Manni, Simona, Boffa, Iolanda, Caruso, Simona, Di Cecca, Stefano, Sinibaldi, Matilde, Abbaszadeh, Zeinab, Camera, Antonio, Ciccone, Roselia, Polito, Vinicia Assunta, Ferrandino, Francesca, Reddel, Sofia, Catanoso, Maria Luigia, Bocceri, Emilia, Del Bufalo, Francesca, Algeri, Mattia, De Angelis, Biagio, Quintarelli, Concetta, Locatelli, Franco

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Manipulating the Metabolism to Improve the Efficacy of CAR T-Cell Immunotherapy von Pellegrino, Marsha, Del Bufalo, Francesca, De Angelis, Biagio, Quintarelli, Concetta, Caruana, Ignazio, de Billy, Emmanuel

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The peculiar challenge of bringing CAR-T cells into the brain: Perspectives in the clinical application to the treatment of pediatric central nervous system tumors von Del Baldo, Giada, Del Bufalo, Francesca, Pinacchio, Claudia, Carai, Andrea, Quintarelli, Concetta, De Angelis, Biagio, Merli, Pietro, Cacchione, Antonella, Locatelli, Franco, Mastronuzzi, Angela

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FGFR1 is a potential therapeutic target in neuroblastoma von Cimmino, Flora, Montella, Annalaura, Tirelli, Matilde, Avitabile, Marianna, Lasorsa, Vito Alessandro, Visconte, Feliciano, Cantalupo, Sueva, Maiorino, Teresa, De Angelis, Biagio, Morini, Martina, Castellano, Aurora, Locatelli, Franco, Capasso, Mario, Iolascon, Achille

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Next-Generation Sequencing Approaches for the Identification of Pathognomonic Fusion Transcripts in Sarcomas: The Experience of the Italian ACC Sarcoma Working Group von Racanelli, Dominga, Brenca, Monica, Baldazzi, Davide, Goeman, Frauke, Casini, Beatrice, De Angelis, Biagio, Guercio, Marika, Milano, Giuseppe Maria, Tamborini, Elena, Busico, Adele, Dagrada, Gianpaolo, Garofalo, Cecilia, Caruso, Chiara, Brunello, Antonella, Pignochino, Ymera, Berrino, Enrico, Grignani, Giovanni, Scotlandi, Katia, Parra, Alessandro, Hattinger, Claudia Maria, Ibrahim, Toni, Mercatali, Laura, De Vita, Alessandro, Carriero, Maria Vincenza, Pallocca, Matteo, Loria, Rossella, Covello, Renato, Sbaraglia, Marta, Dei Tos, Angelo Paolo, Falcioni, Rita, Maestro, Roberta

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Establishment and Characterization of a Cell Line (S-RMS1) Derived from an Infantile Spindle Cell Rhabdomyosarcoma with SRF-NCOA2 Fusion Transcript von Colletti, Marta, Galardi, Angela, Miele, Evelina, Di Paolo, Virginia, Russo, Ida, De Stefanis, Cristiano, De Vito, Rita, Rinelli, Martina, Ciolfi, Andrea, De Angelis, Biagio, Zin, Angelica, Guffanti, Alessandro, Digilio, Maria Cristina, Novelli, Antonio, Alaggio, Rita, Milano, Giuseppe Maria, Di Giannatale, Angela

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Identification of New Soluble Factors Correlated With the Development of Graft Failure After Haploidentical Hematopoietic Stem Cell Transplantation von Weber, Gerrit, Strocchio, Luisa, Del Bufalo, Francesca, Algeri, Mattia, Pagliara, Daria, Arnone, Claudia Manuela, De Angelis, Biagio, Quintarelli, Concetta, Locatelli, Franco, Merli, Pietro, Caruana, Ignazio

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