Toward personalized treatment in multiple myeloma based on molecular characteristics von Pawlyn, Charlotte, Davies, Faith E.

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The genetic architecture of multiple myeloma von Morgan, Gareth J., Walker, Brian A., Davies, Faith E.

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Identification of novel mutational drivers reveals oncogene dependencies in multiple myeloma von Walker, Brian A., Mavrommatis, Konstantinos, Wardell, Christopher P., Ashby, T. Cody, Bauer, Michael, Davies, Faith E., Rosenthal, Adam, Wang, Hongwei, Qu, Pingping, Hoering, Antje, Samur, Mehmet, Towfic, Fadi, Ortiz, Maria, Flynt, Erin, Yu, Zhinuan, Yang, Zhihong, Rozelle, Dan, Obenauer, John, Trotter, Matthew, Auclair, Daniel, Keats, Jonathan, Bolli, Niccolo, Fulciniti, Mariateresa, Szalat, Raphael, Moreau, Philippe, Durie, Brian, Stewart, A. Keith, Goldschmidt, Hartmut, Raab, Marc S., Einsele, Hermann, Sonneveld, Pieter, San Miguel, Jesus, Lonial, Sagar, Jackson, Graham H., Anderson, Kenneth C., Avet-Loiseau, Herve, Munshi, Nikhil, Thakurta, Anjan, Morgan, Gareth J.

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From little subclones grow mighty oaks von Boyle, Eileen M., Davies, Faith E.

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Minimal Residual Disease Assessed by Multiparameter Flow Cytometry in Multiple Myeloma: Impact on Outcome in the Medical Research Council Myeloma IX Study von RAWSTRON, Andy C, CHILD, J. Anthony, ROSS, Fiona M, COOK, Gordon, JACKSON, Graham H, MORGAN, Gareth J, OWEN, Roger G, DE TUTE, Ruth M, DAVIES, Faith E, GREGORY, Walter M, BELL, Sue E, SZUBERT, Alexander J, NAVARRO-COY, Nuria, DRAYSON, Mark T, FEYLER, Sylvia

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Clonal selection and double-hit events involving tumor suppressor genes underlie relapse in myeloma von Weinhold, Niels, Ashby, Cody, Rasche, Leo, Chavan, Shweta S., Stein, Caleb, Stephens, Owen W., Tytarenko, Ruslana, Bauer, Michael A., Meissner, Tobias, Deshpande, Shayu, Patel, Purvi H., Buzder, Timea, Molnar, Gabor, Peterson, Erich A., van Rhee, Frits, Zangari, Maurizio, Thanendrarajan, Sharmilan, Schinke, Carolina, Tian, Erming, Epstein, Joshua, Barlogie, Bart, Davies, Faith E., Heuck, Christoph J., Walker, Brian A, Morgan, Gareth J.

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Chromosome 1q21 abnormalities refine outcome prediction in patients with multiple myeloma - a meta-analysis of 2,596 trial patients von Weinhold, Niels, Salwender, Hans J., Cairns, David A., Raab, Marc S., Waldron, George, Blau, Igor W., Bertsch, Uta, Hielscher, Thomas, Morgan, Gareth J., Jauch, Anna, Davies, Faith E., Hanel, Mathias, Cook, Gordon, Scheid, Christoph, Houlston, Richard, Goldschmidt, Hartmut, Jackson, Graham, Kaiser, Martin F.

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Minimal residual disease in myeloma by flow cytometry: independent prediction of survival benefit per log reduction von Rawstron, Andy C., Gregory, Walter M., de Tute, Ruth M., Davies, Faith E., Bell, Sue E., Drayson, Mark T., Cook, Gordon, Jackson, Graham H., Morgan, Gareth J., Child, J. Anthony, Owen, Roger G.

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Whole-body diffusion-weighted MR imaging for assessment of treatment response in myeloma von Giles, Sharon L, Messiou, Christina, Collins, David J, Morgan, Veronica A, Simpkin, Catherine J, West, Sharon, Davies, Faith E, Morgan, Gareth J, deSouza, Nandita M

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The molecular make up of smoldering myeloma highlights the evolutionary pathways leading to multiple myeloma von Boyle, Eileen M., Deshpande, Shayu, Tytarenko, Ruslana, Ashby, Cody, Wang, Yan, Bauer, Michael A., Johnson, Sarah K., Wardell, Christopher P., Thanendrarajan, Sharmilan, Zangari, Maurizio, Facon, Thierry, Dumontet, Charles, Barlogie, Bart, Arbini, Arnaldo, Rustad, Even H., Maura, Francesco, Landgren, Ola, Zhan, Fenghuang, van Rhee, Frits, Schinke, Carolina, Davies, Faith E., Morgan, Gareth J., Walker, Brian A.

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First-line treatment with zoledronic acid as compared with clodronic acid in multiple myeloma (MRC Myeloma IX): a randomised controlled trial von Morgan, Gareth J, Dr, Prof, Davies, Faith E, MD, Gregory, Walter M, Prof, Cocks, Kim, MSc, Bell, Sue E, DPhil, Szubert, Alex J, MSc, Navarro-Coy, Nuria, MPhil, Drayson, Mark T, MD, Owen, Roger G, MD, Feyler, Sylvia, MD, Ashcroft, A John, MD, Ross, Fiona, DPhil, Byrne, Jennifer, MD, Roddie, Huw, MD, Rudin, Claudius, MD, Cook, Gordon, MD, Jackson, Graham H, Prof, Child, J Anthony, Prof

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The spatio-temporal evolution of multiple myeloma from baseline to relapse-refractory states von Rasche, Leo, Schinke, Carolina, Maura, Francesco, Bauer, Michael A., Ashby, Cody, Deshpande, Shayu, Poos, Alexandra M., Zangari, Maurizio, Thanendrarajan, Sharmilan, Davies, Faith E., Walker, Brian A., Barlogie, Bart, Landgren, Ola, Morgan, Gareth J., van Rhee, Frits, Weinhold, Niels

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The presence of large focal lesions is a strong independent prognostic factor in multiple myeloma von Rasche, Leo, Angtuaco, Edgardo J., Alpe, Terri L., Gershner, Grant H., McDonald, James E., Samant, Rohan S., Kumar, Manoj, Van Hemert, Rudy, Epstein, Joshua, Deshpande, Shayu, Tytarenko, Ruslana, Yaccoby, Shmuel, Hillengass, Jens, Thanendrarajan, Sharmilan, Schinke, Carolina, van Rhee, Frits, Zangari, Maurizio, Walker, Brian A., Barlogie, Bart, Morgan, Gareth J., Davies, Faith E., Weinhold, Niels

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The role of maintenance thalidomide therapy in multiple myeloma: MRC Myeloma IX results and meta-analysis von Morgan, Gareth J., Gregory, Walter M., Davies, Faith E., Bell, Sue E., Szubert, Alexander J., Brown, Julia M., Coy, Nuria N., Cook, Gordon, Russell, Nigel H., Rudin, Claudius, Roddie, Huw, Drayson, Mark T., Owen, Roger G., Ross, Fiona M., Jackson, Graham H., Child, J. Anthony

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PIKing the next therapeutic target in multiple myeloma von Caro, Jessica L., Davies, Faith E.

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MAF protein mediates innate resistance to proteasome inhibition therapy in multiple myeloma von Qiang, Ya-Wei, Ye, Shiqiao, Chen, Yu, Buros, Amy F., Edmonson, Ricky, van Rhee, Frits, Barlogie, Bart, Epstein, Joshua, Morgan, Gareth J., Davies, Faith E.

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Global methylation analysis identifies prognostically important epigenetically inactivated tumor suppressor genes in multiple myeloma von Kaiser, Martin F., Johnson, David C., Wu, Ping, Walker, Brian A., Brioli, Annamaria, Mirabella, Fabio, Wardell, Christopher P., Melchor, Lorenzo, Davies, Faith E., Morgan, Gareth J.

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Loss of heterozygosity as a marker of homologous repair deficiency in multiple myeloma: a role for PARP inhibition? von Pawlyn, Charlotte, Loehr, Andrea, Ashby, Cody, Tytarenko, Ruslana, Deshpande, Shayu, Sun, James, Fedorchak, Kyle, Mughal, Tariq, Davies, Faith E., Walker, Brian A., Morgan, Gareth J.

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Aberrant global methylation patterns affect the molecular pathogenesis and prognosis of multiple myeloma von Walker, Brian A., Wardell, Christopher P., Chiecchio, Laura, Smith, Emma M., Boyd, Kevin D., Neri, Antonino, Davies, Faith E., Ross, Fiona M., Morgan, Gareth J.

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Clonal evolution in myeloma: the impact of maintenance lenalidomide and depth of response on the genetics and sub-clonal structure of relapsed disease in uniformly treated newly di... von Jones, John R, Weinhold, Niels, Ashby, Cody, Walker, Brian A, Wardell, Chris, Pawlyn, Charlotte, Rasche, Leo, Melchor, Lorenzo, Cairns, David A, Gregory, Walter M, Johnson, David, Begum, Dil B, Ellis, Sidra, Sherborne, Amy L, Cook, Gordon, Kaiser, Martin F, Drayson, Mark T, Owen, Roger G, Jackson, Graham H, Davies, Faith E, Greaves, Mel, Morgan, Gareth J

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