A Small Molecule Screen in Stem-Cell-Derived Motor Neurons Identifies a Kinase Inhibitor as a Candidate Therapeutic for ALS von Yang, Yin M., Gupta, Shailesh K., Kim, Kevin J., Powers, Berit E., Cerqueira, Antonio, Wainger, Brian J., Ngo, Hien D., Rosowski, Kathryn A., Schein, Pamela A., Ackeifi, Courtney A., Arvanites, Anthony C., Davidow, Lance S., Woolf, Clifford J., Rubin, Lee L.

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Synthetic modified Fezf2 mRNA (modRNA) with concurrent small molecule SIRT1 inhibition enhances refinement of cortical subcerebral/corticospinal neuron identity from mouse embryoni... von Sadegh, Cameron, Ebina, Wataru, Arvanites, Anthony C., Davidow, Lance S., Rubin, Lee L., Macklis, Jeffrey D.

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Large-Scale Production of Mature Neurons from Human Pluripotent Stem Cells in a Three-Dimensional Suspension Culture System von Rigamonti, Alessandra, Repetti, Giuliana G., Sun, Chicheng, Price, Feodor D., Reny, Danielle C., Rapino, Francesca, Weisinger, Karen, Benkler, Chen, Peterson, Quinn P., Davidow, Lance S., Hansson, Emil M., Rubin, Lee L.

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Reversal of β cell de-differentiation by a small molecule inhibitor of the TGFβ pathway von Blum, Barak, Roose, Adam N, Barrandon, Ornella, Maehr, René, Arvanites, Anthony C, Davidow, Lance S, Davis, Jeffrey C, Peterson, Quinn P, Rubin, Lee L, Melton, Douglas A

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A functionally characterized test set of human induced pluripotent stem cells von Wichterle, Hynek, Eggan, Kevin, Boulting, Gabriella L, Kiskinis, Evangelos, Croft, Gist F, Amoroso, Mackenzie W, Oakley, Derek H, Wainger, Brian J, Williams, Damian J, Kahler, David J, Yamaki, Mariko, Davidow, Lance, Rodolfa, Christopher T, Dimos, John T, Mikkilineni, Shravani, MacDermott, Amy B, Woolf, Clifford J, Henderson, Christopher E

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Implementation of a Drug Screening Platform to Target Gch1 Expression in Injured Mouse Dorsal Root Ganglion Neurons von Cronin, Shane J F, Davidow, Lance S, Arvanites, Anthony C, Rubin, Lee L, Penninger, Josef M, Woolf, Clifford J

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Patient hiPSCs Identify Vascular Smooth Muscle Arylacetamide Deacetylase as Protective against Atherosclerosis von Toyohara, Takafumi, Roudnicky, Filip, Florido, Mary H.C., Nakano, Toshiaki, Yu, Haojie, Katsuki, Shunsuke, Lee, Minjin, Meissner, Torsten, Friesen, Max, Davidow, Lance S., Ptaszek, Leon, Abe, Takaaki, Rubin, Lee L., Pereira, Alexandre C., Aikawa, Masanori, Cowan, Chad A.

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Single-Cell Analysis of SMN Reveals Its Broader Role in Neuromuscular Disease von Rodriguez-Muela, Natalia, Litterman, Nadia K., Norabuena, Erika M., Mull, Jesse L., Galazo, Maria José, Sun, Chicheng, Ng, Shi-Yan, Makhortova, Nina R., White, Andrew, Lynes, Maureen M., Chung, Wendy K., Davidow, Lance S., Macklis, Jeffrey D., Rubin, Lee L.

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Assessing kinetics and recruitment of DNA repair factors using high content screens von Martinez-Pastor, Barbara, Silveira, Giorgia G., Clarke, Thomas L., Chung, Dudley, Gu, Yuchao, Cosentino, Claudia, Davidow, Lance S., Mata, Gadea, Hassanieh, Sylvana, Salsman, Jayme, Ciccia, Alberto, Bae, Narkhyun, Bedford, Mark T., Megias, Diego, Rubin, Lee L., Efeyan, Alejo, Dellaire, Graham, Mostoslavsky, Raul

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Patient hiPSCs Identify Vascular Smooth Muscle Arylacetamide Deacetylase as Protective against Atherosclerosis von Toyohara, Takafumi, Roudnicky, Filip, Florido, Mary H.C., Nakano, Toshiaki, Yu, Haojie, Katsuki, Shunsuke, Lee, Minjin, Meissner, Torsten, Friesen, Max, Davidow, Lance S., Ptaszek, Leon, Abe, Takaaki, Rubin, Lee L., Pereira, Alexandre C., Aikawa, Masanori, Cowan, Chad A.

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Genetic modifiers ameliorate endocytic and neuromuscular defects in a model of spinal muscular atrophy von Walsh, Melissa B., Janzen, Eva, Wingrove, Emily, Hosseinibarkooie, Seyyedmohsen, Muela, Natalia Rodriguez, Davidow, Lance, Dimitriadi, Maria, Norabuena, Erika M., Rubin, Lee L., Wirth, Brunhilde, Hart, Anne C.

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A screen for regulators of survival of motor neuron protein levels von Makhortova, Nina R, Hayhurst, Monica, Cerqueira, Antonio, Sinor-Anderson, Amy D, Zhao, Wen-Ning, Heiser, Patrick W, Arvanites, Anthony C, Davidow, Lance S, Waldon, Zachary O, Steen, Judith A, Lam, Kelvin, Ngo, Hien D, Rubin, Lee L

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Tsix , a gene antisense to Xist at the X-inactivation centre von Lee, Jeannie, Davidow, Lance S, Warshawsky, David

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Genetic circuitry of Survival motor neuron, the gene underlying spinal muscular atrophy von Sen, Anindya, Dimlich, Douglas N, Guruharsha, K G, Kankel, Mark W, Hori, Kazuya, Yokokura, Takakazu, Brachat, Sophie, Richardson, Delwood, Loureiro, Joseph, Sivasankaran, Rajeev, Curtis, Daniel, Davidow, Lance S, Rubin, Lee L, Hart, Anne C, Van Vactor, David, Artavanis-Tsakonas, Spyros

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Implementation of a Drug Screening Platform to TargetGch1 Expression in Injured Mouse Dorsal Root Ganglion Neurons von Cronin, Shane J F, Davidow, Lance S, Arvanites, Anthony C, Rubin, Lee L, Penninger, Josef M, Woolf, Clifford J

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CTCF, a Candidate Trans-Acting Factor for X-Inactivation Choice von Chao, Wendy, Huynh, Khanh D., Spencer, Rebecca J., Davidow, Lance S., Lee, Jeannie T.

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The DXPas34 Repeat Regulates Random and Imprinted X Inactivation von Cohen, Dena E., Davidow, Lance S., Erwin, Jennifer A., Xu, Na, Warshawsky, David, Lee, Jeannie T.

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Using Automated Live Cell Imaging to Reveal Early Changes during Human Motor Neuron Degeneration von Shin, Hye Young, Pfaff, Kathleen L, Davidow, Lance S, Sun, Chicheng, Uozumi, Takayuki, Yanagawa, Fumiki, Yamazaki, Yoichi, Kiyota, Yasujiro, Rubin, Lee L

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search for a marsupial XIC reveals a break with vertebrate synteny von Davidow, Lance S, Breen, Matthew, Duke, Shannon E, Samollow, Paul B, McCarrey, John R, Lee, Jeannie T

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Synthetic modified Fezf2 mRNA von Sadegh, Cameron, Ebina, Wataru, Arvanites, Anthony C, Davidow, Lance S, Rubin, Lee L, Macklis, Jeffrey D

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