Precise and in situ genetic humanization of 6 Mb of mouse immunoglobulin genes von Macdonald, Lynn E., Karow, Margaret, Stevens, Sean, Auerbach, Wojtek, Poueymirou, William T., Yasenchak, Jason, Frendewey, David, Valenzuela, David M., Giallourakis, Cosmas C., Alt, Frederick W., Yancopoulos, George D., Murphy, Andrew J.

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IL-22BP is regulated by the inflammasome and modulates tumorigenesis in the intestine von Huber, Samuel, Gagliani, Nicola, Zenewicz, Lauren A., Huber, Francis J., Bosurgi, Lidia, Hu, Bo, Hedl, Matija, Zhang, Wei, O’Connor, William, Murphy, Andrew J., Valenzuela, David M., Yancopoulos, George D., Booth, Carmen J., Cho, Judy H., Ouyang, Wenjun, Abraham, Clara, Flavell, Richard A.

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Multiple knockout mouse models reveal lincRNAs are required for life and brain development von Sauvageau, Martin, Goff, Loyal A, Lodato, Simona, Bonev, Boyan, Groff, Abigail F, Gerhardinger, Chiara, Sanchez-Gomez, Diana B, Hacisuleyman, Ezgi, Li, Eric, Spence, Matthew, Liapis, Stephen C, Mallard, William, Morse, Michael, Swerdel, Mavis R, D'Ecclessis, Michael F, Moore, Jennifer C, Lai, Venus, Gong, Guochun, Yancopoulos, George D, Frendewey, David, Kellis, Manolis, Hart, Ronald P, Valenzuela, David M, Arlotta, Paola, Rinn, John L

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Innate and Adaptive Interleukin-22 Protects Mice from Inflammatory Bowel Disease von Zenewicz, Lauren A., Yancopoulos, George D., Valenzuela, David M., Murphy, Andrew J., Stevens, Sean, Flavell, Richard A.

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ANGPTL3 blockade with a human monoclonal antibody reduces plasma lipids in dyslipidemic mice and monkeys von Gusarova, Viktoria, Alexa, Corey A, Wang, Yan, Rafique, Ashique, Kim, Jee Hae, Buckler, David, Mintah, Ivory J, Shihanian, Lisa M, Cohen, Jonathan C, Hobbs, Helen H, Xin, Yurong, Valenzuela, David M, Murphy, Andrew J, Yancopoulos, George D, Gromada, Jesper

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Diverse Phenotypes and Specific Transcription Patterns in Twenty Mouse Lines with Ablated LincRNAs von Lai, Ka-Man Venus, Gong, Guochun, Atanasio, Amanda, Rojas, José, Quispe, Joseph, Posca, Julita, White, Derek, Huang, Mei, Fedorova, Daria, Grant, Craig, Miloscio, Lawrence, Droguett, Gustavo, Poueymirou, William T, Auerbach, Wojtek, Yancopoulos, George D, Frendewey, David, Rinn, John, Valenzuela, David M

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Trophic niche overlap between coyotes and gray foxes in a temperate forest in Durango, Mexico von Ricardo Rodriguez-Luna, Cesar, Servin, Jorge, Valenzuela-Galvan, David, List, Rurik

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Interleukin-22 but Not Interleukin-17 Provides Protection to Hepatocytes during Acute Liver Inflammation von Zenewicz, Lauren A., Yancopoulos, George D., Valenzuela, David M., Murphy, Andrew J., Karow, Margaret, Flavell, Richard A.

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Cleft Palate, Moderate Lung Developmental Retardation and Early Postnatal Lethality in Mice Deficient in the Kir7.1 Inwardly Rectifying K+ Channel von Villanueva, Sandra, Burgos, Johanna, López-Cayuqueo, Karen I, Lai, Ka-Man Venus, Valenzuela, David M, Cid, L Pablo, Sepúlveda, Francisco V

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Total‐evidence phylogeny and evolutionary morphology of New World pitvipers (Serpentes: Viperidae: Crotalinae) von Carrasco, Paola A., Koch, Claudia, Grazziotin, Felipe G., Venegas, Pablo J., Chaparro, Juan C., Scrocchi, Gustavo J., Salazar‐Valenzuela, David, Leynaud, Gerardo C., Mattoni, Camilo I.

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Human thrombopoietin knockin mice efficiently support human hematopoiesis in vivo von Rongvaux, Anthony, Willinger, Tim, Takizawa, Hitoshi, Rathinam, Chozhavendan, Auerbach, Wojtek, Murphy, Andrew J., Valenzuela, David M., Yancopoulos, George D., Eynon, Elizabeth E., Stevens, Sean, Manz, Markus G., Flavell, Richard A.

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Regulation of the Germinal Center Response by MicroRNA-155 von Thai, To-Ha, Calado, Dinis Pedro, Casola, Stefano, Ansel, K. Mark, Xiao, Changchun, Xue, Yingzi, Murphy, Andrew, Frendewey, David, Valenzuela, David, Kutok, Jeffery L, Schmidt-Supprian, Marc, Rajewsky, Nikolaus, Yancopoulos, George, Rao, Anjana, Rajewsky, Klaus

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Generation of functional multipotent adult stem cells from GPR125 + germline progenitors von Falciatori, Ilaria, Yancopoulos, George D, Rafii, Shahin, Gale, Nicholas W, Hobbs, Robin M, Valenzuela, David M, James, Daylon, Torres, Richard, Zhang, Fan, Murphy, Andrew, Kim, Jiyeon, Shmelkov, Sergey V, Chavala, Sai, Scherr, Douglas S, Pandolfi, Pier Paolo, Seandel, Marco

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Postsymptomatic restoration of SMN rescues the disease phenotype in a mouse model of severe spinal muscular atrophy von Lutz, Cathleen M, Kariya, Shingo, Patruni, Sunita, Osborne, Melissa A, Liu, Don, Henderson, Christopher E, Li, Darrick K, Pellizzoni, Livio, Rojas, José, Valenzuela, David M, Murphy, Andrew J, Winberg, Margaret L, Monani, Umrao R

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SIRT4 Inhibits Glutamate Dehydrogenase and Opposes the Effects of Calorie Restriction in Pancreatic β Cells von Haigis, Marcia C., Mostoslavsky, Raul, Haigis, Kevin M., Fahie, Kamau, Christodoulou, Danos C., Murphy, Andrew J., Valenzuela, David M., Yancopoulos, George D., Karow, Margaret, Blander, Gil, Wolberger, Cynthia, Prolla, Tomas A., Weindruch, Richard, Alt, Frederick W., Guarente, Leonard

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RORγ-Expressing Th17 Cells Induce Murine Chronic Intestinal Inflammation via Redundant Effects of IL-17A and IL-17F von Leppkes, Moritz, Becker, Christoph, Ivanov, Ivaylo I, Hirth, Sebastian, Wirtz, Stefan, Neufert, Clemens, Pouly, Sandrine, Murphy, Andrew J, Valenzuela, David M, Yancopoulos, George D, Becher, Burkhard, Littman, Dan R, Neurath, Markus F

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Neurons expressing trace amine-associated receptors project to discrete glomeruli and constitute an olfactory subsystem von Johnson, Mark A., Tsai, Lulu, Roy, Dheeraj S., Valenzuela, David H., Mosley, Colleen, Magklara, Angeliki, Lomvardas, Stavros, Liberles, Stephen D., Barnea, Gilad

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Divergence of tropical pitvipers promoted by independent colonization events of dry montane Andean habitats von Salazar‐Valenzuela, David, Kuch, Ulrich, Torres‐Carvajal, Omar, Valencia, Jorge H., Gibbs, H. Lisle

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Glucagon Receptor Blockade With a Human Antibody Normalizes Blood Glucose in Diabetic Mice and Monkeys von Okamoto, Haruka, Kim, Jinrang, Aglione, JohnPaul, Lee, Joseph, Cavino, Katie, Na, Erqian, Rafique, Ashique, Kim, Jee Hae, Harp, Joyce, Valenzuela, David M, Yancopoulos, George D, Murphy, Andrew J, Gromada, Jesper

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Protective effects of angiopoietin-like 4 on cerebrovascular and functional damages in ischaemic stroke von Bouleti, Claire, Mathivet, Thomas, Coqueran, Berard, Serfaty, Jean-Michel, Lesage, Mathieu, Berland, Elodie, Ardidie-Robouant, Corinne, Kauffenstein, Gilles, Henrion, Daniel, Lapergue, Bertrand, Mazighi, Mikael, Duyckaerts, Charles, Thurston, Gavin, Valenzuela, David M, Murphy, Andrew J, Yancopoulos, George D, Monnot, Catherine, Margaill, Isabelle, Germain, Stephane

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