The N‑Methylated Peptide SEN304 Powerfully Inhibits Aβ(1–42) Toxicity by Perturbing Oligomer Formation von Amijee, Hozefa, Bate, Clive, Williams, Alun, Virdee, Jasmeet, Jeggo, Ross, Spanswick, David, Scopes, David I.C, Treherne, J. Mark, Mazzitelli, Sonia, Chawner, Ross, Eyers, Claire E, Doig, Andrew J

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Orally bioavailable small molecule drug protects memory in Alzheimer's disease models von O'Hare, Eugene, Scopes, David I.C, Kim, Eun-Mee, Palmer, Philip, Jones, Martyn, Whyment, Andrew D, Spanswick, David, Amijee, Hozefa, Nerou, Edmund, McMahon, Bridgeen, Treherne, J. Mark, Jeggo, Ross

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Rhodanine-3-acetic acid derivatives as inhibitors of fungal protein mannosyl transferase 1 (PMT1) von Orchard, Michael G, Neuss, Judi C, Galley, Carl M.S, Carr, Andrew, Porter, David W, Smith, Phillip, Scopes, David I.C, Haydon, David, Vousden, Katherine, Stubberfield, Colin R, Young, Kate, Page, Martin

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Novel 5-aryloxypyrimidine SEN1576 as a candidate for the treatment of Alzheimer's disease von O'Hare, Eugene, Scopes, David I.C., Kim, Eun-Mee, Palmer, Philip, Spanswick, David, McMahon, Bridgeen, Amijee, Hozefa, Nerou, Edmund, Treherne, J. Mark, Jeggo, Ross

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Glyco- and Peptidomimetics from Three-Component Joullié−Ugi Coupling Show Selective Antiviral Activity von Chapman, Timothy M, Davies, Ieuan G, Gu, Baohua, Block, Timothy M, Scopes, David I. C, Hay, Philip A, Courtney, Stephen M, McNeill, Luke A, Schofield, Christopher J, Davis, Benjamin G

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RS-0406 Arrests Amyloid-β Oligomer-Induced Behavioural Deterioration In Vivo von O’Hare, Eugene, Scopes, David I.C., Treherne, J. Mark, Norwood, Kelly, Spanswick, David, Kim, Eun-Mee

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Dose-dependent improvements in learning and memory deficits in APPPS1-21 transgenic mice treated with the orally active Aβ toxicity inhibitor SEN1500 von Lo, Adrian C., Tesseur, Ina, Scopes, David I.C., Nerou, Edmund, Callaerts-Vegh, Zsuzsanna, Vermaercke, Ben, Treherne, J. Mark, De Strooper, Bart, D'Hooge, Rudi

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Furanyl-1,3-thiazol-2-yl and benzoxazol-5-yl acetic acid derivatives: novel classes of heparanase inhibitor von Courtney, Stephen M., Hay, Philip A., Buck, Richard T., Colville, Claire S., Phillips, David J., Scopes, David I.C., Pollard, Faye C., Page, Martin J., Bennett, James M., Hircock, Margaret L., McKenzie, Edward A., Bhaman, Maina, Felix, Robert, Stubberfield, Colin R., Turner, Paul R.

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2,3-Dihydro-1,3-dioxo-1H-isoindole-5-carboxylic acid derivatives: a novel class of small molecule heparanase inhibitors von COURTNEY, Stephen M, HAY, Philip A, MCKENZIE, Edward A, STUBBERFIELD, Colin R, TURNER, Paul R, BUCK, Richard T, COLVILLE, Claire S, PORTER, David W, SCOPES, David I. C, POLLARD, Faye C, PAGE, Martin J, BENNETT, James M, HIRCOCK, Margaret L

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A Convenient Route to Imino Sugars and Analogues of Siastatin B von Birch, Nicola J., Parsons, Phillip J., Scopes, David I.

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P2-358: SEN1269: A novel inhibitor of amyloid-beta toxicity von Scopes, David I, Amijee, Hozefa, Nerou, Edmund, Treherne, Mark, O'Hare, Eugene, Jeggo, Ross, Whyment, Andrew, Spanswick, David

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P2-295: β-amyloid aggregation inhibitors for the treatment of Alzheimer's disease von Doig, Andrew J, Amijee, Hozefa, Scopes, David I.C, Treherne, J. Mark

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In Vivo Drug Screening in C.Elegans Identifies Novel Compounds that Inhibit Aβ1-42 Toxicity von Sattelle, David B, Fraboulet, Sandrine, Moloney, Aileen M, Nussher, Anja, Jones, Andrew K, Buckingham, Stephen D, Amijee, Hozefa, Scopes, David I.C, Treherne, Mark, Link, Christopher D

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Evolution of a Novel Series of [(N,N-Dimethylamino)propyl]- and Piperazinylbenzanilides as the First Selective 5-HT1D Antagonists von Clitherow, John W, Scopes, David I. C, Skingle, Malcolm, Jordan, Christopher C, Feniuk, Wasyl, Campbell, Ian B, Carter, Malcolm C, Collington, Eric W, Connor, Helen E

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A potent new class of .kappa.-receptor agonist: 4-substituted 1-(arylacetyl)-2-[(dialkylamino)methyl]piperazines von Naylor, Alan, Judd, Duncan B, Lloyd, Jane E, Scopes, David I. C, Hayes, Ann G, Birch, Philip J

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Enantiomerically pure amines by a new method: biotransformation of oxalamic esters using the lipase from Candida antarctica von Chapman, Daniel T., Crout, David H. G., Mahmoudian, Mahmoud, Scopes, David I. C., Smith, Paul W.

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Bromobenzofuran-Based Non-peptide Antagonists of Angiotensin II: GR138950, a Potent Antihypertensive Agent with High Oral Bioavailability von Judd, Duncan B, Dowle, Michael D, Middlemiss, David, Scopes, David I. C, Ross, Barry C, Jack, Torquil I, Pass, Martin, Tranquillini, Elvira, Hobson, Julie E

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New .kappa.-receptor agonists based upon a 2-[(alkylamino)methyl]piperidine nucleus von Scopes, David I. C, Hayes, Norman F, Bays, David E, Belton, David, Brain, John, Brown, Dearg S, Judd, Duncan B, McElroy, Andrew B, Meerholz, Clive A

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RS-0406 Arrests Amyloid-b Oligomer-Induced Behavioural Deterioration In Vivo von O'Hare, Eugene, Scopes, David IC, Treherne, JMark, Norwood, Kelly, Spanswick, David, Kim, Eun-Mee

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4-[(Alkylamino)methyl]furo[3,2-c]pyridines: A New Series of Selective .kappa.-Receptor Agonists von Naylor, Alan, Judd, Duncan B, Scopes, David I. C, Hayes, Ann G, Birch, Philip J

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